The bZIP transcription factor ATFx binds human T-cell leukemia virus type 1 (HTLV-1) tax and represses HTLV-1 long terminal repeat-mediated transcription

Journal of Virology

Volumn 79, Issue 11, 2005, Pages 6932-6939

  Forgacs, Eva ^a   Gupta, Saurabh K ^a   Kerry, Julie A ^a   Semmes, O John ^a,b  

^a EASTERN VIRGINIA MEDICAL SCHOOL   (United States)

^b NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR X; BINDING PROTEIN; CYCLIC AMP; TAX PROTEIN; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BINDING AFFINITY; CELL CYCLE; CYCLIC AMP RESPONSIVE ELEMENT; GEL MOBILITY SHIFT ASSAY; GENETIC TRANSCRIPTION; HOMEOSTASIS; HUMAN T CELL LEUKEMIA VIRUS 1; LONG TERMINAL REPEAT; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ACTIVATING TRANSCRIPTION FACTORS; BASE SEQUENCE; BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS; BLOOD PROTEINS; CELL LINE; DNA; DNA-BINDING PROTEINS; G-BOX BINDING FACTORS; GENE PRODUCTS, TAX; HUMAN T-LYMPHOTROPIC VIRUS 1; HUMANS; PROTEIN BINDING; RECOMBINANT FUSION PROTEINS; REPRESSOR PROTEINS; RNA, MESSENGER; TERMINAL REPEAT SEQUENCES; TISSUE DISTRIBUTION; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

HTLV; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN T-LYMPHOTROPIC VIRUS 1;

EID: 18744379157     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.79.11.6932-6939.2005     Document Type: Article

References (55)

1. Adya, N., and C. Z. Giam. 1995. Distinct regions in human T-cell lymphotropic virus type I tax mediate interactions with activator protein CREB and basal transcription factors. J. Virol. 69:1834-1841.
2. Alexandre, C., and B. Verrier. 1991. Four regulatory elements in the human c-fos promoter mediate transactivation by HTLV-1 Tax protein. Oncogene 6:543-551.
3. Anderson, M. G., and W. S. Dynan. 1994. Quantitative studies of the effect of HTLV-I Tax protein on CREB protein-DNA binding. Nucleic Acids Res. 22:3194-3201.
4. Brady, J., K. T. Jeang, J. Duvall, and G. Khoury. 1987. Identification of p40x-responsive regulatory sequences within the human T-cell leukemia virus type I long terminal repeat. J. Virol. 61:2175-2181.
5. Brauweiler, A., P. Garl, A. A. Franklin, H. A. Giebler, and J. K. Nyborg. 1995. A molecular mechanism for human T-cell leukemia virus latency and Tax transactivation. J. Biol. Chem. 270:12814-12822.
6. Chau, N. H., C. D. Vanson, and J. A. Kerry. 1999. Transcriptional regulation of the human cytomegalovirus US11 early gene. J. Virol. 73:863-870.
7. Chen, I. S., D. J. Slamon, J. D. Rosenblatt, N. P. Shah, S. G. Quan, and W. Wachsman. 1985. The x gene is essential for HTLV replication. Science 229:54-58.
8. Dodon, M. D., Z. Li, S. Hamaia, and L. Gazzolo. 2004. Tax protein of human T-cell leukaemia virus type 1 induces interleukin 17 gene expression in T cells. J. Gen. Virol. 85:1921-1932.
9. Ego, T., Y. Ariumi, and K. Shimotohno. 2002. The interaction of HTLV-1 Tax with HDACl negatively regulates the viral gene expression. Oncogene 21:7241-7246.
10. Felber, B. K., H. Paskalis, C. Kleinman-Ewing, F. Wong-Staal, and G. N. Pavlakis. 1985. The pX protein of HTLV-1 is a transcriptional activator of its long terminal repeats. Science 229:675-679.
11. Franklin, A. A., M. F. Kubik, M. N. Uittenbogaard, A. Brauweiler, P. Utaisincharoen, M. A. Matthews, W. S. Dynan, J. P. Hoeffler, and J. K. Nyborg. 1993. Transactivation by the human T-cell leukemia virus Tax protein is mediated through enhanced binding of activating transcription factor-2 (ATF-2) ATF-2 response and cAMP element-binding protein (CREB). J. Biol. Chem. 268:21225-21231.
12. Fujisawa, J., M. Seiki, M. Sato, and M. Yoshida. 1986. A transcriptional enhancer sequence of HTLV-I is responsible for trans-activation mediated by p40 chi HTLV-I. EMBO J. 5:713-718.
13. Gachon, F., S. Thebault, A. Peleraux, C. Devaux, and J. M. Mesnard. 2000. Molecular interactions involved in the transactivation of the human T-cell leukemia virus type 1 promoter mediated by Tax and CREB-2 (ATF-4). Mol. Cell. Biol. 20:3470-3481.
14. Gatza, M. L., J. C. Watt, and S. J. Marriott. 2003. Cellular transformation by the HTLV-I Tax protein, a jack-of-all-trades. Oncogene 22:5141-5149.
15. Georges, S. A., W. L. Kraus, K. Luger, J. K. Nyborg, and P. J. Laybourn. 2002. p300-mediated tax transactivation from recombinant chromatin: histone tail deletion mimics coactivator function. Mol. Cell. Biol. 22:127-137.
16. Gessain, A., F. Barin, J. C. Vernant, O. Gout, L. Maurs, A. Calender, and G. de The. 1985. Antibodies to human T-lymphotropic virus type-I in patients with tropical spastic paraparesis. Lancet 2:407-410.
17. Giebler, H. A., J. E. Loring, K. van Orden, M. A. Colgin, J. E. Garnis, K. W. Escudero, A. Brauweiler, and J. K. Nyborg. 1997. Anchoring of CREB binding protein to the human T-cell leukemia virus type 1 promoter: a molecular mechanism of Tax transactivation. Mol. Cell. Biol. 17:5156-5164.
18. Goren, I., O. J. Semmes, K. T. Jeang, and K. Moelling. 1995. The amino terminus of Tax is required for interaction with the cyclic AMP response element binding protein. J. Virol. 69:5806-5811.
19. Gorman, C. M., L. F. Moffat, and B. H. Howard. 1982. Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol. Cell. Biol. 2:1044-1051.
20. Graham, F. L., and A. J. van der Eb. 1973. Transformation of rat cells by DNA of human adenovirus 5. Virology 54:536-539.
21. Haoudi, A., R. C. Daniels, E. Wong, G. Kupfer, and O. J. Semmes. 2003. Human T-cell leukemia virus-I tax oncoprotein functionally targets a subnuclear complex involved in cellular DNA damage-response. J. Biol. Chem. 278:37736-37744.
22. Harrod, R., Y. L. Kuo, Y. Tang, Y. Yao, A. Vassilev, Y. Nakatani, and C. Z. Giam. 2000. p300 and p300/cAMP-responsive element-binding protein associated factor interact with human T-cell lymphotropic virus type-1 Tax in a multi-histone acetyltransferase/activator-enhancer complex. J. Biol. Chem. 275:11852-11857.
23. Hivin, P., G. Gaudray, C. Devaux, and J. M. Mesnard. 2004. Interaction between C/EBPbeta and Tax down-regulates human T-cell leukemia virus type I transcription. Virology 318:556-565.
24. Jeang, K. T., S. G. Widen, O. J. Semmes, and S. H. Wilson. 1990. HTLV-I trans-activator protein, tax, is a trans-repressor of the human beta-polymerase gene. Science 247:1082-1084.
25. Jiang, H., H. Lu, R. L. Schiltz, C. A. Pise-Masison, V. V. Ogryzko, Y. Nakatani, and J. N. Brady. 1999. PCAF interacts with tax and stimulates tax transactivation in a histone acetyltransferase-independent manner. Mol. Cell. Biol. 19:8136-8145.
26. Kimzey, A. L., and W. S. Dynan. 1998. Specific regions of contact between human T-cell leukemia virus type I Tax protein and DNA identified by photocross-linking. J. Biol. Chem. 273:13768-13775.
27. Kwok, R. P., M. E. Laurance, J. R. Lundblad, P. S. Goldman, H. Shih, L. M. Connor, S. J. Marriott, and R. H. Goodman. 1996. Control of cAMP-regulated enhancers by the viral transactivator Tax through CREB and the coactivator CBP. Nature 380:642-646.
28. Lenzmeier, B. A., H. A. Giebler, and J. K. Nyborg. 1998. Human T-cell leukemia virus type 1 Tax requires direct access to DNA for recruitment of CREB binding protein to the viral promoter. Mol. Cell. Biol. 18:721-731.
29. Newbound, G. C., J. P. O'Rourke, N. D. Collins, J. M. Andrews, J. DeWille, and M. D. Lairmore. 2000. Repression of tax-mediated human t-lymphotropic virus type 1 transcription by inducibie cAMP early repressor (ICER) protein in peripheral blood mononuclear cells. J. Med. Virol 62:286-292.
30. Ogryzko, V. V., R. L. Schiltz, V. Russanova, B. H. Howard, and Y. Nakatani. 1996. The transcriptional coactivators p300 and CBP are histone acetyltransferases. Cell 87:953-959.
31. Osame, M., K. Usuku, S. Izumo, N. Ijichi, H. Amitani, A. Igata, M. Matsumoto, and M. Tara. 1986. HTLV-I associated myelopathy, a new clinical entity. Lancet i:1031-1032.
32. Paca-Uccaralertkun, S., L. J. Zhao, N. Adya, J. V. Cross, B. R. Cullen, I. M. Boros, and C. Z. Giam. 1994. In vitro selection of DNA elements highly responsive to the human T-cell lymphotropic virus type I transcriptional activator, Tax. Mol. Cell. Biol. 14:456-462.
33. Park, H. U., J. H. Jeong, J. H. Chung, and J. N. Brady. 2004. Human T-cell leukemia virus type 1 Tax interacts with Chk1 and attenuates DNA-damage induced G(2) arrest mediated by Chk1. Oncogene 23:4966-4974.
34. Paskalis, H., B. K. Felber, and G. N. Pavlakis. 1986. Cis-acting sequences responsible for the transcriptional activation of human T-cell leukemia virus type I constitute a conditional enhancer. Proc. Natl. Acad. Sci. USA 83: 6558-6562.
35. Pati, D., M. L. Meistrich, and S. E. Plon. 1999. Human Cdc34 and Rad6B ubiquitin-conjugating enzymes target repressors of cyclic AMP-induced transcription for proteolysis. Mol. Cell. Biol. 19:5001-5013.
36. Perini, G., S. Wagner, and M. R. Green. 1995. Recognition of bZIP proteins by the human T-cell leukaemia virus transactivator Tax. Nature 376:602-605.
37. Persengiev, S. P., L. R. Devireddy, and M. R. Green. 2002. Inhibition of apoptosis by ATFx: a novel role for a member of the ATF/CREB family of mammalian bZIP transcription factors. Genes Dev. 16:1806-1814.
38. Peters, C. S., X. Liang, S. Li, S. Kannan, Y. Peng, R. Taub, and R. H. Diamond. 2001. ATF-7, a novel bZIP protein, interacts with the PRL-1 protein-tyrosine phosphatase. J. Biol. Chem. 276:13718-13726.
39. Poiesz, B. J., F. W. Ruscetti, A. F. Gazdar, P. A. Bunn, J. D. Minna, and R. C. Gallo. 1980. Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma. Proc. Natl. Acad. Sci. USA 77:7415-7419.
40. Seiki, M., J. Inoue, T. Takeda, and M. Yoshida. 1986. Direct evidence that p40x of human T-cell leukemia virus type I is a trans-acting transcriptional activator. EMBO J. 5:561-565.
41. Semmes, O. J., J. F. Barret, C. V. Dang, and K. T. Jeang. 1996. Human T-cell leukemia virus type I tax masks c-Myc function through a cAMP-dependent pathway. J. Biol. Chem. 271:9730-9738.
42. Semmes, O. J., and K. T. Jeang. 1992. Mutational analysis of human T-cell leukemia virus type I Tax: regions necessary for function determined with 47 mutant proteins. J. Virol. 66:7183-7192.
43. Sodroski, J. G., C. A. Rosen, and W. A. Haseltine. 1984. Trans-acting transcriptional activation of the long terminal repeat of human T lymphotropic viruses in infected cells. Science 225:381-385.
44. Suzuki, T., J. I. Fujisawa, M. Toita, and M. Yoshida. 1993. The transactivator tax of human T-cell leukemia virus type 1 (HTLV-1) interacts with cAMP-responsive element (CRE) binding and CRE modulator proteins that bind to the 21-base-pair enhancer of HTLV-1. Proc. Natl. Acad. Sci. USA 90:610-614.
45. Suzuki, T., T. Narita, M. Uchida-Toita, and M. Yoshida. 1999. Down-regulation of the INK4 family of cyclin-dependent kinase inhibitors by tax protein of HTLV-1 through two distinct mechanisms. Virology 259:384-391.
46. Suzuki, T., M. Uchida-Toita, and M. Yoshida. 1999. Tax protein of HTLV-1 inhibits CBP/p300-mediated transcription by interfering with recruitment of CBP/p300 onto DNA element of E-box or p53 binding site. Oncogene 18:4137-4143.
47. Vidai, M., P. Braun, E. Chen, J. D. Boeke, and E. Harlow. 1996. Genetic characterization of a mammalian protein-protein interaction domain by using a yeast reverse two-hybrid system. Proc. Natl. Acad. Sci. USA 93:10321-10326.
48. Wagner, S., and M. R. Green. 1993. HTLV-I Tax protein stimulation of DNA binding of bZIP proteins by enhancing dimerization. Science 262:395-399.
49. Yin, M. J., and R. B. Gaynor. 1996. Complex formation between CREB and Tax enhances the binding affinity of CREB for the human T-cell leukemia virus type 1 21-base-pair repeats. Mol. Cell. Biol. 16:3156-3168.
50. Yin, M. J., E. J. Paulssen, J. S. Seeler, and R. B. Gaynor. 1995. Protein domains involved in both in vivo and in vitro interactions between human T-cell leukemia virus type I tax and CREB. J. Virol. 69:3420-3432.
51. Yoshida, M. 1994. Tenth anniversary perspectives on AIDS. Host-HTLV type I interaction at the molecular level. AIDS Res. Hum. Retroviruses. 10:1193-1197.
52. Yoshida, M., J. Inoue, J. Fujisawa, and M. Seiki. 1989. Molecular mechanisms of regulation of HTLV-1 gene expression and its association with leukemogenesis. Genome 31:662-667.
53. Yoshida, M., M. Seiki, K. Yamaguchi, and K. Takatsuki. 1984. Monoclonal integration of human T-cell leukemia provirus in all primary tumors of adult T-cell leukemia suggests causative role of human T-cell leukemia virus in the disease. Proc. Natl. Acad. Sci. USA 81:2534-2537.
54. Zhao, L. J., and C. Z. Giam. 1992. Human T-cell lymphotropic virus type I (HTLV-I) transcriptional activator, Tax, enhances CREB binding to HTLV-I 21-base-pair repeats by protein-protein interaction. Proc. Natl. Acad. Sci. USA 89:7070-7074.
55. Zhao, L. J., and C. Z. Giam. 1991. Interaction of the human T-cell lymphotrophic virus type I (HTLV-I) transcriptional activator Tax with cellular factors that bind specifically to the 21-base-pair repeats in the HTLV-I enhancer. Proc. Natl. Acad. Sci. USA 88:11445-11449.