Identification of a massive reserve of hematopoietic progenitors in mice

Stem Cells and Development

Volumn 14, Issue 2, 2005, Pages 105-110

  Broxmeyer, Hal E ^a,b   Cooper, Scott ^a,b   Lasky, Laurence A ^c,d   De Sauvage, Frederic ^c  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WALTHER CANCER INSTITUTE   (United States)

^c GENENTECH INC   (United States)

^d Latterell Venture Partners   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; CELL SURFACE PROTEIN; PROTEIN C MPL; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BLOOD; CONTROLLED STUDY; ERYTHROID PRECURSOR CELL; HEMATOPOIETIC STEM CELL; MEGAKARYOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN; STEADY STATE; WILD TYPE;

ANIMALS; ANTIGENS, CD34; BONE MARROW; CELL DIFFERENTIATION; CELL NUCLEUS; ERYTHROID PROGENITOR CELLS; FEMUR; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HEMATOPOIETIC STEM CELLS; HUMANS; MEGAKARYOCYTES; MICE; MICE, TRANSGENIC; MYELOID PROGENITOR CELLS; SPLEEN; STEM CELLS;

EID: 18744371028     PISSN: 15473287     EISSN: None     Source Type: Journal    
DOI: 10.1089/scd.2005.14.105     Document Type: Article

References (13)

1. Broxmeyer HE. (1993). Role of cytokines in hematopoiesis. In: Clinical Aspects of Cytokines: Role in Pathogenesis, Diagnosis and Therapy. JJ Oppenheim, JL Rossio and AJH Gearing, eds. Oxford University Press, New York, pp 201-206.
2. th ed. R Hoffman, E Benz, S Shattil, B Furie, H Cohen, L Silberstein and P McGlave, eds. pp 233-265.
3. Krause DS, T Ito, MJ Fackler, OM Smith, MI Collector, SJ Sharks and WS May. (1994). Characterization of murine CD34, a marker for hematopoietic progenitor and stem cells. Blood 84:691-701.
4. Cheng J, S Baumhueter, H Thibodeaux. R Thomas, HE Broxmeyer, S Cooper, N Hague, G Cacalano, M Moore and LA Lasky. (1996). Hematopoietic defects in mice lacking the sialomucin CD34. Blood 87:479-490.
5. Suzuki A, DP Andrew, JA Gonzalo, M Fukumoto, J Spellberg, M Hashiyama, H Takimoto, N Gerwin, I Webb, G Molineux, R Amakawa, Y Tada, A Wakeham, J Brown, I McNiece, K Ley, EC Butcher, T Suda, JC Gutierrez-Ramos and T Mak. (1996). CD34-Deficient mice have reduced eosinophil accumulation after allergen exposure and show a novel crossreaction 90-kD Protein. Blood 87:3550-3562.
6. Gurney AL, K Carver-Moore, FJ de Sauvage and MW Moore. (1994). Thrombocytopenia in c-mpl-Deficient Mice. Science 265:1445-1447.
7. Carver-Moore, K., HE Broxmeyer, SM Luoh, S Cooper, J Peng, S Burstein, MW Moore and FJ de Sauvage. (1996). Low levels of erythroid and myeloid progenitors in TPO and c-mpl deficient mice. Blood 88:803-808.
8. Alexander WS, AW Roberts, NA Nicola, R Li and D Metcalf. (1996). Deficiency in progenitor cells of multiple hematopoietic lineages and defective megakaryocytopoiesis in mice lacking the thrombopoietin receptor c-Mpl. Blood 87:2162-2170.
9. Murone M, DA Carpenter and FJ de Sauvage. (1998). Hematopoietic deficiencies in c-mpl and TPO knockout mice. Stem Cells 16:1-6.
10. Cooper S and HE Broxmeyer. (1996). Measurement of interleukin-3 and other hematopoietic growth factors, such as GM-CSF, G-CSF, M-CSF, erythropoietin and the potent co-stimulating cytokines steel factor and Flt-3 ligand. In: Current Protocols in Immunology. JE Coligan, AM Kruisbeek, DH Margulies, EM Shevach, W Strober and R Coico, eds. John Wiley & Sons, Inc., New York, Suppl 18, pp 6.4.1-6.4.12.
11. Broxmeyer, HE, G Van Zant. JR Zucali, J LoBue and AS Gordon. (1974). Mechanisms of leukocyte production and release XII. A comparative assay of the leukocytosis-inducing factor (LIF) and the colony stimulating factor (CSF). Proc Soc Expl Bio Med 145:1262-1267.
12. Van Zant G, HE Broxmeyer, J LoBue and AS Gordon. (1973). Rat hind leg perfusion: correlation of bone marrow leukocyte cellularity with release. Am J Physiol 225:1327-1332.
13. Broxmeyer HE, G Van Zant, EF Schultz, J LoBue and AS Gordon. (1975). Glass wool separation of rat PMNs according to adherence and maturity. J Reticuloendothelial Soc 18:118-124.