Anticonvulsant hypersensitivity syndrome from addition of lamotrigine to divalproex [3]

American Journal of Psychiatry

Volumn 162, Issue 5, 2005, Pages 1021-

  Rahman, Mohamed ^a   Haider, Nadeem ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; AMFEBUTAMONE; ASPARTATE AMINOTRANSFERASE; CLONAZEPAM; HYDROXYZINE; LAMOTRIGINE; LITHIUM; TRAZODONE; VALPROATE SEMISODIUM;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANTICONVULSANT HYPERSENSITIVITY SYNDROME; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BIPOLAR DISORDER; CASE REPORT; DIARRHEA; DRUG ERUPTION; DRUG POTENTIATION; DRUG TOLERABILITY; DRUG WITHDRAWAL; EOSINOPHILIA; FEMALE; HEADACHE; HUMAN; HYPERSENSITIVITY; LETTER; LEUKOCYTE COUNT; LIVER NECROSIS; LYMPHADENOPATHY; MALAISE; NAUSEA; PANCYTOPENIA; PHARYNGITIS; PRIORITY JOURNAL; SEIZURE; SYNDROME;

EID: 18744370771     PISSN: 0002953X     EISSN: None     Source Type: Journal    
DOI: 10.1176/appi.ajp.162.5.1021     Document Type: Letter

References (4)

1. Faught E, Morris G, Jacobson M, French J, Harden C, Montouris G, Rosenfeld W (Postmarketing Antiepileptic Drug Survey [PADS] Group): Adding lamotrigine to valproate: incidence of rash and other adverse effects. Epilepsia 1999; 40:1135-1140
2. Schlienger RG, Knowles SR, Shear NH: Lamotrigine-associated anticonvulsant hypersensitivity syndrome. Neurology 1998; 51:1172-1175
3. Calabrese JR, Sullivan JR, Bowden CL, Suppes T, Goldberg JF, Sachs GS, Shelton MD, Goodwin FK, Frye MA, Kusumakar V: Rash in multicenter trials of lamotrigine in mood disorders: clinical relevance and management. J Clin Psychiatry 2002; 63: 1012-1019
4. Guberman AH, Besag FM, Brodie MJ, Dooley JM, Duchowny MS, Pellock JM, Richens A, Stern RS, Trevathan E: Lamotrigine-associated rash: risk/benefit considerations in adults and children. Epilepsia 1999; 40:985-991