Effect of isoproterenol on the regulation of rabbit airway ciliary beat frequency measured with high-speed digital and fluorescence microscopy

Annals of Otology, Rhinology and Laryngology

Volumn 114, Issue 5, 2005, Pages 399-403

  Zhang, Luo ^a   Han, Demin ^b,c   Sanderson, Michael J ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b BEIJING INSTITUTE OF OTOLARYNGOLOGY   (China)

^c CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Calcium; Cilia; Epithelium; Protein kinase A; Trachea

Indexed keywords

CALCIUM; CYCLIC AMP DEPENDENT PROTEIN KINASE; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; ISOPRENALINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CILIARY MOTILITY; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVATION; FLUORESCENCE MICROSCOPY; NONHUMAN; PRIORITY JOURNAL; RABBIT; RESPIRATORY EPITHELIUM;

EID: 18744364439     PISSN: 00034894     EISSN: None     Source Type: Journal    
DOI: 10.1177/000348940511400512     Document Type: Article

References (27)

1. Tamaoki J, Kobayashi K, Sakai N, et al. Atrial natriuretic factor inhibits ciliary motility in cultured rabbit tracheal epithelium. Am J Physiol 1991;260:C201-C205.
2. + and cAMP. Am J Physiol 1992;263:L232-L242.
3. Jain B, Rubinstein I, Robbins RA, Leise KL, Sisson JH. Modulation of airway epithelial cell ciliary beat frequency by nitric oxide. Biochem Biophys Res Commun 1993;191:83-8.
4. Geary CA, Davis CW, Paradiso AM, Boucher RC. Role of CNP in human airways: cGMP-mediated stimulation of ciliary beat frequency. Am J Physiol 1995;268:L1021-L1028.
5. Runer T, Lindberg S. Ciliostimulatory effects mediated by nitric oxide. Acta Otolaryngol (Stockh) 1999;119:821-5.
6. Yang B, Schlosser RJ, McCaffrey TV. Signal transduction pathways in modulation of ciliary beat frequency by methacholine. Ann Otol Rhinol Laryngol 1997;106:230-6.
7. Wyatt TA, Spurzem JR, May K, Sisson JH. Regulation of ciliary beat frequency by both PKA and PKG in bovine airway epithelial cells. Am J Physiol 1998;275:L827-L835.
8. +]i enhances ciliary activity in rabbit trachea. J Physiol 1999;516:179-90.
9. Li D, Shirakami G, Zhan X, Johns RA. Regulation of ciliary beat frequency by the nitric oxide-cyclic guanosine monophosphate signaling pathway in rat airway epithelial cells. Am J Respir Cell Mol Biol 2000;23:175-81.
10. Shirakami G, Li D, Zhan X, Johns RA. Propofol stimulates ciliary motility via the nitric oxide-cyclic GMP pathway in cultured rat tracheal epithelial cells. Anesthesiology 2000;93: 482-8.
11. Braiman A, Uzlaner N, Priel Z. Enhancement of CBF is dominantly controlled by PKG and/or PKA. In: Salathe M, ed. Cilia and mucus. From development to respiratory defense. New York, NY: Marcel Dekker, 2001:67-79.
12. Zagoory O, Braiman A, Priel Z. The mechanism of ciliary stimulation by acetylcholine: roles of calcium, PKA, and PKG. J Gen Physiol 2002;119:329-39.
13. Zhang L, Sanderson MJ. The role of cGMP in the regulation of rabbit airway ciliary beat frequency. J Physiol 2003; 551:765-76.
14. Sanderson MJ, Dirksen ER. Mechanosensitive and beta-adrenergic control of the ciliary beat frequency of mammalian respiratory tract cells in culture. Am Rev Respir Dis 1989;139: 432-40.
15. Yang B, Schlosser RJ, McCaffrey TV. Dual signal transduction mechanisms modulate ciliary beat frequency in upper airway epithelium. Am J Physiol 1996;270:L745-L751.
16. Frohock JI, Wijkstrom-Frei C, Salathe M. Effects of albuterol enantiomers on ciliary beat frequency in ovine tracheal epithelial cells. J Appl Physiol 2002;92:2396-402.
17. Porter ME, Sale WS. The 9 + 2 axoneme anchors multiple inner arm dyneins and a network of kinases and phosphatases that control motility. J Cell Biol 2000;151:F37-F42.
18. Walczak CE, Nelson DL. In vitro phosphorylation of ciliary dyneins by protein kinases from Paramecium. J Cell Sci 1993;106:1369-76.
19. Zhang L, Sanderson MJ. Oscillations in ciliary beat frequency and intracellular calcium concentration in rabbit tracheal epithelial cells induced by ATP. J Physiol 2003;546:733-49.
20. Dirksen ER, Felix JA, Sanderson MJ. Preparation of explant and organ cultures and single cells from airway epithelium. Methods Cell Biol 1995;47:65-74.
21. Leybaert L, Sneyd J, Sanderson MJ. A simple method for high temporal resolution calcium imaging with dual excitation dyes. Biophys J 1998;75:2025-9.
22. Korngreen A, Priel Z. Simultaneous measurement of ciliary beating and intracellular calcium. Biophys J 1994;67:377-80.
23. Sisson JH, Stoner JA, Ammons BA, Wyatt TA. All-digital image capture and whole-field analysis of ciliary beat frequency. J Microsc 2003;211:103-11.
24. Sanderson MJ, Dirksen ER. A versatile and quantitative computer-assisted photoelectronic technique used for the analysis of ciliary beat cycles. Cell Motil 1985;5:267-92.
25. Bennett WD. Effect of beta-adrenergic agonists on mucociliary clearance. J Allergy Clin Immunol 2002;110(suppl): S291-S297.
26. Salathe M. Effects of beta-agonists on airway epithelial cells. J Allergy Clin Immunol 2002;110(suppl):S275-S281.
27. Cooper DM, Mons N, Karpen JW. Adenylyl cyclases and the interaction between calcium and cAMP signalling. Nature 1995;374:421-4.