Co-factors p300 and CBP catch Egr1 in their network

Prostate

Volumn 63, Issue 4, 2005, Pages 407-410

  Adamson, Eileen D ^a   Yu, Jianxiu ^a   Mustelin, Tomas ^a  

^a BURNHAM INSTITUTE   (United States)

Author keywords

Acetylation; Apoptosis; Coactivation; CREBBP (CBP); Early growth response gene 1; Feedback loops; Growth; p300; p53; Phosphorylation; Prostate cancer cells; Serum stimulation; UV C irradiation

Indexed keywords

EARLY GROWTH RESPONSE FACTOR 1; PROTEIN P300; TRANSCRIPTION FACTOR;

ACETYLATION; ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER CELL; CANCER GENETICS; CELL DEATH; CELL GROWTH; CELL TYPE; DOWN REGULATION; FEEDBACK SYSTEM; GENE EXPRESSION; IRRADIATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; UPREGULATION;

DNA-BINDING PROTEINS; EARLY GROWTH RESPONSE PROTEIN 1; HUMANS; IMMEDIATE-EARLY PROTEINS; MALE; NUCLEAR PROTEINS; PROSTATE; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 18644385226     PISSN: 02704137     EISSN: None     Source Type: Journal    
DOI: 10.1002/pros.20186     Document Type: Article

References (21)

1. Debes JD, Sebo TJ, Lohse CM, Murphy LM, Haugen de AL, Tindall DJ. p300 in prostate cancer proliferation and progression. Cancer Res 2003;63(22):7638- 7640.
2. Ionov YS, Matsui JK, Cowell JK. A role for p300/CREB binding protein genes in promoting cancer progression in colon cancer cell lines with microsatellite instability. Proc Natl Acad Sci USA 2004;101(5):1273-1278. E-pub 2004 Jan 19.
3. Iyer NG, Ozdag H, Caldas C. p300/CBP and cancer. Oncogene 2004;23(24):4225-4231.
4. Yu J, de Belle I, Liang H, Adaruson ED. Co-activating factors p300 and CBP are transcriptionally cross-regulated by Egr1 in prostate cells, leading to divergent responses. Mol Cell 2004;15(1):83-94.
5. Silverman ES, Du J, De Sanctis GT, Radmark O, Samuelsson B, Drazen JM, Collins T. Egr-1 and Sp1 interact functionally with the 5-lipoxygenase promoter and its naturally occurring mutants. Am J Respir Cell Mol Biol 1998;19(2):316-323.
6. Silverman ES, Du J, Williams AJ, Wadgaonkar R, Drazen JM, Collins T. cAMP-response-element-binding-protein-binding protein (CBP) and p300 are transcriptional co-activators of early growth response factor-1 (Egr-1). Biochem J 1998; 336(Pt 1):183-189.
7. Jain N, Mahendran R, Philp R, Guy GR, Tan YH, Cao X. Casein kinase II associates with Egr-1 and acts as a negative modulator of its DNA binding and transcription activities in NIH 3T3 cells. J Biol Chem 1996;271(23):13530-15336.
8. Virolle T, Adamson ED, Baron V, Birle D, Mercola D, Mustelin T, de Belle I. The Egr-1 transcription factor directly activates PTEN during irradiation-induced signalling. Nat Cell Biol 2001;3(12):1124-1128.
9. Svaren J, Sevetson BR, Apel ED, Zimonjic DB, Popescu NC, Milbrandt J. NAB2, a corepressor of NGFI-A (Egr-1) and Krox20, is induced by proliferative and differentiative stimuli. Mol Cell Biol 1996;16(7):3545-3553.
10. Abdulkadir SA, Qu ZC, Garabedian E, Song SK, Peters TJ, Svaren J, Carbone JM, Naughton CK, Catalona WJ, Ackerman JJH, Gordon JI, Humphrey PA, Milbrandt J. Impaired prostate tumorigenesis in Egr1-deficient mice. Nat Med 2001;7(1):101-107.
11. Baron V, De Gregorio G, Krones-Herzig A, Virolle T, Calogero A, Urcis R, Mercola D. Inhibition of Egr1 expression reverses transformation of prostate cancer cells in vitro and in vivo. Oncogene 2003;22:4204-4294.
12. Baron V, Duss S, Rhim J, Mercola D. Antisense to the early growth response-1 gene (Egr-1) inhibits prostate tumor development in TRAMP mice. Ann NY Acad Sci 2003;1002:197-216.
13. Huang RP, Fan Y, de Belle I, Niemeyer C, Gottardis MM, Mercola D, Adamson ED. Decreased Egr-1 expression in human, mouse, and rat mammary cells and tissues correlates with tumor formation. Int J Cancer 1997;72:102-109.
14. Levin WJ, Press MF, Gaynor RB, Sukhatme VP, Boone TC, Slamon DJ, Group, Members of the Lung Cancer Study. Expression patterns of immediate early transcription factors in human non-small cell lung cancer. The Lung Cancer Study Group. Oncogene 1995;11:1261-1269.
15. Liu J, Grogen L, Nau MM, Allegra CJ, Chu E, Wright JJ. Physical interaction between p53 and primary response gene Egr-1. Int J Oncol 2001;18(4):863-870.
16. Nair P, Muthukkumar S, Sells SF, Han SS, Sukhatme VP, Rangnekar VM. Early growth response-1-dependent apoptosis is mediated by p53. J Biol Chem 1997;272:20131-20138.
17. Ahmed MM, Venkatasubbarao K, Fruitwala SM, Muthukkumar S, Wood DP Jr, Sells SF, Mohiuddin M, Rangnekar VM. EGR-1 induction is required for maximal radiosensitivity in A375-C6 melanoma cells. J Biol Chem 1996;271(46):29231- 29237.
18. Krones-Herzig A, Adamson E, Mercola D. Early growth response 1 protein, an upstream gatekeeper of the p53 tumor suppressor, controls replicative senescence. Proc Natl Acad Sci USA 2003;100(6):3233-3238.
19. Watts GS, Oshiro MM, Junk DJ, Wozniak RJ, Watterson S, Dornann FE, Futscher BW. The acetyltransferase p300/CBP-associated factor is a p53 target gene in breast tumor cells. Neoplasia 2004;6(3):187-194.
20. Luo J, Li M, Tang Y, Laszkowska M, Roeder RG, Gu W. Acetylation of p53 augments its site-specific DNA binding both in vitro and in vivo. Proc Natl Acad Sci USA 2004;101(8):2259-2264.
21. Dornan D, Shimizu H, Perkins ND, Hupp TR. DNA-dependent acetylation of p53 by the transcription coactivator p300. J Biol Chem 2003;278(15):13431-13441.