Relating the structure, activity, and physical properties of ultrashort-acting benzodiazepine receptor agonists

Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 21, 2002, Pages 3219-3222

  Pacofsky, Gregory J ^a,b   Stafford, Jeffrey A ^a,c   Cox, Richard F ^a   Cowan, Jill R ^a   Dorsey, George F ^a   Gonzales, Stephen S ^a   Kaldor, Istvan ^a   Koszalka, George W ^a   Lovell, George G ^a   McIntyre, Maggie S ^a   Tidwell, Jeffrey H ^a   Todd, Dan ^a   Whitesell, Graham ^a   Wiard, Robert P ^a   Feldman, Paul L ^a  

^a GLAXOSMITHKLINE   (United States)

^b Takeda San Diego Inc   (United States)

^c Chrysalon   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BENZODIAZEPINE RECEPTOR; BENZODIAZEPINE RECEPTOR STIMULATING AGENT;

ARTICLE; BINDING AFFINITY; CYCLIZATION; DRUG ACTIVITY; DRUG SOLUBILITY; DRUG SYNTHESIS; PHYSICAL CHEMISTRY; STRUCTURE ACTIVITY RELATION;

ANIMALS; BENZODIAZEPINES; DRUG DESIGN; INDICATORS AND REAGENTS; MOLECULAR CONFORMATION; MUSCULOSKELETAL EQUILIBRIUM; RATS; RECEPTORS, GABA-A; SOLUBILITY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 18644377334     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(02)00513-9     Document Type: Article

References (18)

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