Cutting edge: The acquisition of TLR tolerance during malaria infection impacts T cell activation

Journal of Immunology

Volumn 174, Issue 10, 2005, Pages 5921-5925

  Perry, James A ^a   Olver, Christine S ^a   Burnett, Robert C ^a   Avery, Anne C ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CD11B ANTIGEN; CD19 ANTIGEN; CD3 ANTIGEN; GAMMA INTERFERON; GLYCOPROTEIN P 15095; INTERLEUKIN 10; INTERLEUKIN 12; MEROZOITE SURFACE PROTEIN 1; TOLL LIKE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DENDRITIC CELL; IMMUNE RESPONSE; IMMUNOLOGICAL TOLERANCE; INFLAMMATION; KNOCKOUT MOUSE; MALARIA; MOUSE; NONHUMAN; PARASITEMIA; PHENOTYPE; PLASMODIUM YOELII; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION; SALMONELLA TYPHI; T LYMPHOCYTE ACTIVATION;

EID: 18644373611     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.174.10.5921     Document Type: Article

References (30)

1. Breman, J. G. 2001. The ears of the hippopotamus: manifestations, determinants, and estimates of the malaria burden. Am. J. Trop. Med. Hyg. 64: 1-11.
2. Kwiatkowski, D., A. V. Hill, I. Sambou, P. Twumasi, J. Castracane, K. R. Manogue, A. Cerami, D. R. Brewster, and B. M. Greenwood. 1990. TNF concentration in fatal cerebral, non-fatal cerebral, and uncomplicated Plasmodium falciparum malaria. Lancet 336: 1201-1204.
3. Kurtzhals, J. A., V. Adabayeri, B. Q. Goka, B. D. Akanmori, J. O. Oliver-Commey, F. K. Nkrumah, C. Behr, and L. Hviid. 1998. Low plasma concentrations of interleukin 10 in severe -malarial anaemia compared with cerebral and uncomplicated malaria. Lancet 351: 1768-1772.
4. Orhoro, C., A, A. Lal, B. Nahlen, D. Koech, A. S. Orago, and V. Udhayakumar. 1999. A low interleukin-10 tumor necrosis factor-α ratio is associated with malaria anemia in children residing in a holoendemic malaria region in western Kenya. J. Infect. Dis. 1999: 279-282.
5. Langhorne, J. R., F. Albano, M. Hensmann, L. Sanni, E, Cadman, C. Voisine, and A. M. Sponaas. 2004. Dendritic cells, pro-inflammatory responses, and antigen presentation in a rodent malaria infection. Immunol. Rev. 201: 35-47.
6. Li, C., I. Corraliza, and J. Langhorne. 1999. A defect in interleukin-10 leads to enhanced malarial disease in Plasmodium chabaudi chabaudi infection in mice. Infect. Immun. 67: 4435-4442.
7. Omer, F. M., and E. M. Riley, 1998. Transforming growth factor b production is inversely correlated with severity of murine malaria infection. J. Exp. Med. 188: 39-48.
8. Tsutsui, N., and T. Kamiyama. 1999. Transforming growth factor β-induced failure of resistance to infection with blood-stage Plasmodium chabaudi in mice. Infect. Immun. 67:2306-2311.
9. Linke, A., R. Kuhn, W. Muller, N. Honarvar, C. Li, and J. Langhorne. 1996. Plasmodium chabaudi chabaudi: differential susceptibility of gene-targeted mice deficient in IL-10 to an erythrocytic-stage infection. Exp. Parasitol 84: 253-263.
10. Moser, M., and K. M. Murphy. 2000. Dendritic cell regulation of Th1-Th2 development, Nat. Immunol. 1: 199-205.
11. Perry, J. A., A. Rush, R. J. Wilson, C. S. Olver, and A. C. Avery. 2004. Dendritic cells from malaria infected mice are fully functional antigen presenting cells. J. Immunol. 172: 475-482.
12. Luyendyk, J. L., O. R. Olivas, L. A. Ginger, and A. C. Avery. 2002. Antigen-presenting cell function during Plasmodium yoelii infection. Infect. Immun. 70: 2941-2949.
13. Takeda, K., T. Kaisho, and S. Akira. 2003. Toll-like receptors. Annu. Rev. Immunol. 21: 335-376.
14. Sato, S., O. Takeuchi, T. Fujita, H. Tomizawa, K. Takeda, and S. Akira. 2002. A variety of microbial components induce tolerance to lipopolysaccharide by differentially affecting MyD88-dependent and -independent pathways. Int. Immunol. 14: 783-791.
15. Wysocka, M., S. Robertson, H. Riemann, J. Caamano, C. A. Hunter, A. Mackiewicz, L. J. Montaner, G. Trinchieri, and C. L. Karp. 2001, IL-12 suppression during experimental endotoxin tolerance: dendritic cell loss and macrophage hyporesporisiveness. J. Immunol 166:7504-7513.
16. Varma, T. K., T. E. Toliver-Kinsky, C. Y. Lin, A. P. Kourrouvelis, J. E. Nichols, and E. R. Sherwood. 2001. Cellular mechanisms that cause suppressed γ interferon secretion in endotoxin-tolerant mice. Infect. Immun. 69: 5249-5263.
17. Pulendran, B., J. Lingappa, M. K. Kennedy, J. Smith, M. Teepe, A. Rudensky, and C. R. Maliszewski. 1997. Development pathways of dendritic cells in vivo. J. Immunol. 159:2222-2231.
18. Omer, F. M., J. B. de Souza, and E. M. Riley. 2003. Differential induction of TGF-β regulates proinflammatory cytokine production and determines the outcome of lethal and nonlethal Plasmodium yoelii infections. J. Immunol. 171: 5430-5436.
19. Li, C., L. A. Sanni, F. M. Omet, E. Riley, and J. Langhorne. 2003. Pathology of Plasmodium chabaudi chabaudi infection and mortality in interleukin-10 deficient mice are meliorated by anti-tumor necrosis factor α and exacerbated by antitransforming growth factor β antibodies. Infect. Immun. 71: 4850-4856.
20. Sly, L. M., M. J. Rauh, J. Kalesnikoff, C. H. Song, and G. Krystal. 2004. LPS-induced upregulation of SHIP is essential for endotoxin tolerance. Immunity 21: 227-239.
21. Ocana-Morgner, C., M. M. Mota, and A. Rodriguez. 2003. Malaria blood stage suppression of liver stage immunity by dendritic cells. J. Exp. Med. 197: 143-151.
22. Urban, B.C., D. J. Ferguson, A. Pain, N. Willcox, M. Plebanski, J. M. Austyn, and D. J. Roberts. 1999. Plasmodium falciparum-infected erythrocytes modulate the maturation of dendritic cells. Nature 400: 73-77.
23. Leisewitz, A. L., K. A. Rockett, B. Gumede, M. Jones, B. Urban, and D. B. Kwiatkowski. 2004. Response of the splenic dendritic cell population to malaria infection. Inject. Immun. 72: 4233-4239.
24. Pouniotis, D. S., O. Proudfoot, V. Bogdanoska, V. Apostolopoulos, T. Fifis, and M. Plebanski. 2004. Dendritic cells induce immunity and long-lasting protection against blood-stage malaria despite an in vitro parasite-induced maturation defect. Infect. Immun. 72: 5331-5339.
25. Dobrovolskaia, M. A., A. E, Medvedev, K. E. Thomas, N. Cuesta, V. Toshchakov, T. Ren, M. J. Cody, S. M. Michalek, N. R. Rice, and S. N. Vogel. 2003. Induction of in vitro reprogramming by Toll-like receptor (TLR)2 and TLR4 agonists in murine macrophages; effects of TLR "homotolerance" versus "heterotolerance" on NF-κB signaling pathway components. J. Immunol. 170: 508-519.
26. Coban, C., K. J. Ishii, T. Kawai, H. Hemmi, S. Sato, S. Uematsu, M. Yamamoto, O. Takeuchi, S. Itagaki, N. Kumar, T. Horii, and S. Akira. 2005. Toll-like receptor 9 mediates innate immune activation by the malaria pigment hernoioin. J. Exp. Med. 201: 19-25.
27. Yeo, S. J., J. G. Yoon, S. C. Hong, and A. K. Yi. 2003. CpG DNA induces self and cross-hyporesponsiveness of RAW264.7 cells in response to CpG DNA and lipopolysaccharide: alterations in IL-1 receptor-associated kinase expression. J. Immunol 170: 1052-1061.
28. Rubenstein, M., J. H. Mulholland, G. M. Jeffrey, and S. M. Wolff. 1965. Malaria induced endotoxin tolerance. Proc. Soc. Exp. Biol. Med. 118: 283-287.
29. Kaisho, T., O. Takeuchi, T. Kawai, K. Hoshino, and S. Akira. 2001. Endotoxin-induced maturation of MyD88-deficient dendritic cells. J. Immunol. 166: 5688-5694.
30. Gupta, S., R. W. Snow, C. A, Donnelly, K. Marsh, and C. Newbold. 1999. Immunity to non-cerebral severe malaria is acquired after one or two infections. Nat. Med. 5: 340-343.