Impaired ascorbic acid metabolism in streptozotocin-induced diabetic rats

Free Radical Biology and Medicine

Volumn 33, Issue 9, 2002, Pages 1221-1230

  Kashiba, Misato ^a   Oka, Jun ^a   Ichikawa, Rumi ^a   Kasahara, Emiko ^c   Inayama, Takayo ^a   Kageyama, Asako ^a   Kageyama, Haruaki ^a   Osaka, Toshimasa ^a   Umegaki, Keizo ^a   Matsumoto, Akiyo ^a   Ishikawa, Takahiro ^b   Nishikimi, Morimitsu ^b   Inoue, Masayasu ^c   Inoue, Shuji ^a  

^a NATIONAL INSTITUTE OF HEALTH AND NUTRITION   (Japan)

^b WAKAYAMA MEDICAL UNIVERSITY   (Japan)

^c OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Ascorbic acid; Diabetes; Free radicals; L gulono gamma lactone oxidase; Reductive regeneration

Indexed keywords

ASCORBIC ACID; GULONOLACTONE OXIDASE; OXIDOREDUCTASE; STREPTOZOCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASCORBIC ACID METABOLISM; BIOSYNTHESIS; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION; KIDNEY; KIDNEY TUBULE ABSORPTION; LIVER LEVEL; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; STREPTOZOCIN DIABETES; TIME; URINARY EXCRETION; URINE VOLUME; VITAMIN BLOOD LEVEL;

ANIMALS; ASCORBIC ACID; BLOTTING, NORTHERN; BLOTTING, WESTERN; CELLS, CULTURED; DEHYDROASCORBIC ACID; DIABETES MELLITUS, EXPERIMENTAL; DNA PRIMERS; DOSE-RESPONSE RELATIONSHIP, DRUG; KIDNEY; L-GULONOLACTONE OXIDASE; LIVER; LIVER REGENERATION; MALE; MICROSOMES, LIVER; NADP; ORGANIC ANION TRANSPORTERS, SODIUM-DEPENDENT; OXIDATIVE STRESS; OXIDOREDUCTASES; POLYMERASE CHAIN REACTION; RATS; RATS, WISTAR; RNA, MESSENGER; SUGAR ALCOHOL DEHYDROGENASES; SYMPORTERS;

EID: 18644367318     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(02)01010-9     Document Type: Article

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