Antibodies to GAD in Japanese patients classified as Type 2 diabetes at diagnosis. High titre of GAD Ab is a predictive marker for early insulin treatment - Report of west Japan (Kyushu, Yamaguchi, Osaka) study for GAD Ab(+) diabetes

Diabetic Medicine

Volumn 19, Issue 9, 2002, Pages 730-734

  Takino, H ^a   Yamasaki, H ^a   Abiru, N ^a   Sera, Y ^a   Abe, T ^a   Kawasaki, E ^a   Yamaguchi, Y ^a   Eguchi, K ^a   Kanazawa, Y ^b   Nagataki, S ^c  

^a NAGASAKI UNIVERSITY   (Japan)

^b JICHI MEDICAL UNIVERSITY   (Japan)

^c RADIATION EFFECTS RESEARCH FOUNDATION   (Japan)

Author keywords

GAD Ab; Insulin treatment; Type 2 diabetes

Indexed keywords

GLUTAMATE DECARBOXYLASE; GLUTAMATE DECARBOXYLASE ANTIBODY; INSULIN; ORAL ANTIDIABETIC AGENT;

ADULT; ANAMNESIS; ANTIBODY TITER; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DIET THERAPY; DISEASE CLASSIFICATION; DISEASE DURATION; DISEASE MARKER; FEMALE; FOLLOW UP; HUMAN; INSULIN TREATMENT; JAPAN; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PREDICTION; TREATMENT INDICATION;

ADULT; AGE OF ONSET; AUTOANTIBODIES; BIOLOGICAL MARKERS; DIABETES MELLITUS, TYPE 2; FEMALE; FOLLOW-UP STUDIES; GLUTAMATE DECARBOXYLASE; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES;

EID: 18544379634     PISSN: 07423071     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1464-5491.2002.00646.x     Document Type: Article

References (14)

1. Molecular cloning and identification of a receptor-type protein tyrosine phosphates, IA-2, from human insulinoma
2. Immunogenetic and clinical characterisation of slowly progressive IDDM
3. Antibodies to glutamic acid decarboxylase reveal latent autoimmune diabetes mellitus in adults with a non-insulin-dependent onset of disease
4. Glutamic decarboxylase antibody level predicts rate of B-cell declining in adult-onset diabetes
5. Islet cell antibodies against glutamic acid decarboxylase in newly diagnosed adult-onset diabetes mellitus
6. Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance
7. Autoantibodies to glutamic acid decarboxylase in patients with IDDM and autoimmune thyroid disease
8. High level of concordance between assays for glutamic acid decarboxylase antibodies. The first glutamic acid decarboxylase antibody workshop
9. Autoantibodies to glutamic acid decarboxylase in patients with autoimmune thyroid disease: Relation to competitive insulin autoantibodies
10. Evaluation of islet cell antigen (ICA) 512/IA-2 autoantibody radioassay using overlapping ICA512/IA-2 constructs
11. GAD antibodies in NIDDM
12. UKPDS 25: Autoantibodies to islet-cell cytoplasm and glutamic acid decarboxylase for prediction of insulin requirement in type 2 diabetes
13. Low prevalence of autoantibodies to GAD65 in a 50- to 74 year-old general Dutch population
14. A comparison of the epidemiology of youth-onset insulin dependent diabetes mellitus between Japan and United States of America (Allerghemy county, Pensyl)