How fast are UV-dimers repaired in human skin DNA in situ?

Journal of Investigative Dermatology

Volumn 119, Issue 3, 2002, Pages 699-

  Hemminki, Kari ^a   Snellman, Erna ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

DIMER; DNA; NUCLEOTIDE; THYMIDINE;

ARTICLE; CONTROLLED STUDY; CROSS LINKING; DNA DAMAGE; DNA REPAIR; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RADIATION DOSE; ULTRAVIOLET IRRADIATION;

EID: 18544375779     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1747.2002.00289.x     Document Type: Article

References (8)

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2. Bykov VJ, Sheehan JM, Hemminki K, Young AR: In situ repair of cyclobutane dimers and 6-4 photoproducts in human skin exposed to solar simulating radiation. J Invest Dermatol 112:326-331, 1999
3. Fichtinger-Schepman AM, Baan RA, Berends F: Influence of the degree of DNA modification on the immunochemical determination of cisplatin-DNA adduct levels. Carcinogenesis 10:2367-2369, 1989
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5. Hemminki K, Xu G, Kause L, Koulu LM, Zhao C, Jansen CT: Demonstration of UV-dimers in human skin DNA in situ 3 weeks after exposure. Carcinogenesis 23:605-609, 2002
6. Sheehan JM, Cragg N, Chadwick CA, Potten CS, Young AR: Repeated ultraviolet exposure affords the same protection against DNA photodamage and erythema in human skin types II and IV but is associated with faster DNA repair in skin type IV. J Invest Dermatol 118:825-829, 2002
7. Xu G, Marcusson JA, Hemminki K: DNA photodamage induced by UV phototherapy lamps and sunlamps in human skin in situ and its potential importance for skin cancer. J Invest Dermatol 116:194-195, 2001
8. Zhao C, Snellman E, Jansen CT, Hemminki K: In situ repair of cyclobutane pyrimidine dimers in skin and melanocytic nevi of cutaneous melanoma patients. Int J Cancer 98:331-334, 2002