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Volumn 3, Issue 1, 2004, Pages

Using importance sampling to improve simulation in linkage analysis

Author keywords

Change of probability measure; Cost adjusted relative efficiency; Exponential tilting; Genome wide significance; Importance sampling; Marker information; Nonparametric linkage analysis; Variance reduction

Indexed keywords

ARTICLE; GENE LOCUS; GENOME; LINKAGE ANALYSIS; PROBABILITY; SAMPLING; SIMULATION; COST; HYPOTHESIS; NONPARAMETRIC TEST; STATISTICAL MODEL; VARIANCE;

EID: 18544367812     PISSN: 15446115     EISSN: 15446115     Source Type: Journal    
DOI: 10.2202/1544-6115.1049     Document Type: Article
Times cited : (9)

References (33)
  • 1
    • 0036338150 scopus 로고    scopus 로고
    • Merlin - Rapid analysis of dense genetic maps using sparse gene flow trees
    • Abecasis, G. R., Cherny, S. S., Cookson, W. O. and Cardon, L. R. (2002). Merlin - rapid analysis of dense genetic maps using sparse gene flow trees. Nature Genetics, 30, 97-101.
    • (2002) Nature Genetics , vol.30 , pp. 97-101
    • Abecasis, G.R.1    Cherny, S.S.2    Cookson, W.O.3    Cardon, L.R.4
  • 4
    • 0022792421 scopus 로고
    • Estimating the power of a proposed linkage study: A practical computer simulation approach
    • Boehnke, M. (1986). Estimating the power of a proposed linkage study: A practical computer simulation approach. American Journal of Human Genetics, 39, 513-527.
    • (1986) American Journal of Human Genetics , vol.39 , pp. 513-527
    • Boehnke, M.1
  • 6
    • 0029112753 scopus 로고
    • Two-locus maximum lod score analysis of a multifactorial trait: Joint consideration of IDDM2 and IDDM4 with IDDM1 in type 1 diabetes
    • Cordell, H. J., Todd, J. A., Bennett, S. T., Kawaguchi, Y. and Farrall, M. (1995). Two-locus maximum lod score analysis of a multifactorial trait: Joint consideration of IDDM2 and IDDM4 with IDDM1 in type 1 diabetes. American Journal of Human Genetics, 57, 920-934.
    • (1995) American Journal of Human Genetics , vol.57 , pp. 920-934
    • Cordell, H.J.1    Todd, J.A.2    Bennett, S.T.3    Kawaguchi, Y.4    Farrall, M.5
  • 7
    • 0020711374 scopus 로고
    • The probability that related individuals share some section of the genome identical by descent
    • Donnelly, K. P. (1983). The probability that related individuals share some section of the genome identical by descent. Theoretical Population Biology, 23, 34-64.
    • (1983) Theoretical Population Biology , vol.23 , pp. 34-64
    • Donnelly, K.P.1
  • 8
    • 0027487931 scopus 로고
    • Gaussian models for genetic linkage analysis using complete high-resolution maps of identity by descent
    • Feingold, E., Brown, P. O. and Siegmund, D. (1993). Gaussian models for genetic linkage analysis using complete high-resolution maps of identity by descent. American Journal of Human Genetics, 53, 234-251.
    • (1993) American Journal of Human Genetics , vol.53 , pp. 234-251
    • Feingold, E.1    Brown, P.O.2    Siegmund, D.3
  • 9
    • 51249172774 scopus 로고
    • An analysis of Monte Carlo algorithms for counting problems
    • Frigessi, A. and Vercellis, C. (1985). An analysis of Monte Carlo algorithms for counting problems. Calcolo, 22(4), 413-428.
    • (1985) Calcolo , vol.22 , Issue.4 , pp. 413-428
    • Frigessi, A.1    Vercellis, C.2
  • 10
    • 0034098774 scopus 로고    scopus 로고
    • Allegro, a new computer program for multipoint linkage analysis
    • Gudbjartsson, D. F., Jonasson, K., Frigge, M. and Kong, A. (2000). Allegro, a new computer program for multipoint linkage analysis. Nature Genetics, 25, 12-13.
    • (2000) Nature Genetics , vol.25 , pp. 12-13
    • Gudbjartsson, D.F.1    Jonasson, K.2    Frigge, M.3    Kong, A.4
  • 12
    • 0141574406 scopus 로고    scopus 로고
    • Asymptotic estimation theory of multipoint linkage analysis under perfect marker information
    • Hössjer, O. (2003a). Asymptotic estimation theory of multipoint linkage analysis under perfect marker information. Annals of Statistics, 31(4), 1075-1109.
    • (2003) Annals of Statistics , vol.31 , Issue.4 , pp. 1075-1109
    • Hössjer, O.1
  • 13
    • 14644436877 scopus 로고    scopus 로고
    • (Tech. Rep. No. 2003:21). Stockholm: Department of Mathematical Statistics, Stockholm University
    • Hössjer, O. (2003b). Spectral decomposition of score functions in linkage analysis (Tech. Rep. No. 2003:21). Stockholm: Department of Mathematical Statistics, Stockholm University.
    • (2003) Spectral Decomposition of Score Functions in Linkage Analysis
    • Hössjer, O.1
  • 14
    • 0030728925 scopus 로고    scopus 로고
    • Allele-sharing models: Lod scores and accurate linkage tests
    • Kong, A. and Cox, N. (1997). Allele-sharing models: Lod scores and accurate linkage tests. American Journal of Human Genetics, 61, 1179-1188.
    • (1997) American Journal of Human Genetics , vol.61 , pp. 1179-1188
    • Kong, A.1    Cox, N.2
  • 15
    • 0026685858 scopus 로고
    • Importance sampling. I. Computing multimodal p-values in linkage analysis
    • Kong, A., Frigge, M., Irwin, M. and Cox, N. (1992). Importance sampling. I. Computing multimodal p-values in linkage analysis. American Journal of Human Genetics, 51, 1413-1429.
    • (1992) American Journal of Human Genetics , vol.51 , pp. 1413-1429
    • Kong, A.1    Frigge, M.2    Irwin, M.3    Cox, N.4
  • 16
    • 14644425091 scopus 로고
    • Importance sampling
    • S. Kotz and N. L. Johnson (Eds.), A Wiley-Interscience Publication: John Wiley & Sons
    • Kotz, S. and Johnson, N. L. (1983). Importance sampling. In S. Kotz and N. L. Johnson (Eds.), Encyclopedia in statistical sciences (Vol. 4, p. 25). A Wiley-Interscience Publication: John Wiley & Sons.
    • (1983) Encyclopedia in Statistical Sciences , vol.4 , pp. 25
    • Kotz, S.1    Johnson, N.L.2
  • 17
    • 14644404135 scopus 로고
    • Tukey's inequality for optimal weights
    • S. Kotz and N. L. Johnson (Eds.), A Wiley-Interscience Publication: John Wiley & Sons
    • Kotz, S. and Johnson, N. L. (1988). Tukey's inequality for optimal weights. In S. Kotz and N. L. Johnson (Eds.), Encyclopedia in statistical sciences (Vol. 9, pp. 361-362). A Wiley-Interscience Publication: John Wiley & Sons.
    • (1988) Encyclopedia in Statistical Sciences , vol.9 , pp. 361-362
    • Kotz, S.1    Johnson, N.L.2
  • 19
    • 0028877463 scopus 로고
    • Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results
    • Lander, E. and Kruglyak, L. (1995). Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results. Nature Genetics, 11, 241-247.
    • (1995) Nature Genetics , vol.11 , pp. 241-247
    • Lander, E.1    Kruglyak, L.2
  • 20
    • 0024508964 scopus 로고
    • Mapping Mendelian factors underlying quantitative traits using RFLP linkage maps
    • Lander, E. S. and Botstein, D. (1989). Mapping Mendelian factors underlying quantitative traits using RFLP linkage maps. Genetics, 121, 185-199.
    • (1989) Genetics , vol.121 , pp. 185-199
    • Lander, E.S.1    Botstein, D.2
  • 22
    • 0032969483 scopus 로고    scopus 로고
    • Optimal allele-sharing statistics for genetic mapping using affected relatives
    • McPeek, M. S. (1999). Optimal allele-sharing statistics for genetic mapping using affected relatives. Genetic Epidemiology, 16, 225-249.
    • (1999) Genetic Epidemiology , vol.16 , pp. 225-249
    • McPeek, M.S.1
  • 23
    • 0035638121 scopus 로고    scopus 로고
    • Computing scan statistic p-values using importance sampling, with applications to genetics and medical image analysis
    • Naiman, D. Q. and Priebe, C. (2001). Computing scan statistic p-values using importance sampling, with applications to genetics and medical image analysis. Journal of Computational and Graphical Statistics, 10(2), 296-328.
    • (2001) Journal of Computational and Graphical Statistics , vol.10 , Issue.2 , pp. 296-328
    • Naiman, D.Q.1    Priebe, C.2
  • 26
    • 0024602536 scopus 로고
    • Estimating the power of a proposed linkage study for a complex genetic trait
    • Ploughman, L. M. and Boehnke, M. (1989). Estimating the power of a proposed linkage study for a complex genetic trait. American Journal of Human Genetics, 44, 543-551.
    • (1989) American Journal of Human Genetics , vol.44 , pp. 543-551
    • Ploughman, L.M.1    Boehnke, M.2
  • 28
    • 0034972488 scopus 로고    scopus 로고
    • A survey of affected-sibship statistics for nonparametric linkage analysis
    • Sengul, H., Weeks, D. E. and Feingold, E. (2001). A survey of affected-sibship statistics for nonparametric linkage analysis. American Journal of Human Genetics, 69, 179-190.
    • (2001) American Journal of Human Genetics , vol.69 , pp. 179-190
    • Sengul, H.1    Weeks, D.E.2    Feingold, E.3
  • 29
    • 0031047461 scopus 로고    scopus 로고
    • Optimal weighting scheme for affected sib-pair analysis of sibship data
    • Sham, P., Zhao, J. and Curtis, D. (1997). Optimal weighting scheme for affected sib-pair analysis of sibship data. Annals of Human Genetics, 61, 61-69.
    • (1997) Annals of Human Genetics , vol.61 , pp. 61-69
    • Sham, P.1    Zhao, J.2    Curtis, D.3
  • 30
    • 0000726013 scopus 로고    scopus 로고
    • Mapping quantitative trait loci in oligogenic models
    • Tang, H. K. and Siegmund, D. (2001). Mapping quantitative trait loci in oligogenic models. Biostatistics, 2, 147-162.
    • (2001) Biostatistics , vol.2 , pp. 147-162
    • Tang, H.K.1    Siegmund, D.2
  • 31
    • 0032447006 scopus 로고    scopus 로고
    • Multipoint linkage analysis using affected relative pairs and partially informative markers
    • Teng, J. and Siegmund, D. (1998). Multipoint linkage analysis using affected relative pairs and partially informative markers. Biometrics, 54, 1247-1265.
    • (1998) Biometrics , vol.54 , pp. 1247-1265
    • Teng, J.1    Siegmund, D.2
  • 32
    • 0027213849 scopus 로고
    • Chromosome-based method for rapid computer simulation in human genetic linkage analysis
    • Terwilliger, J. D., Speer, M. and Ott, J. (1993). Chromosome-based method for rapid computer simulation in human genetic linkage analysis. Genetic Epidemiology, 10, 217-224.
    • (1993) Genetic Epidemiology , vol.10 , pp. 217-224
    • Terwilliger, J.D.1    Speer, M.2    Ott, J.3
  • 33
    • 0028301661 scopus 로고
    • A class of tests for linkage using affected pedigree members
    • Whittemore, A. S. and Halpern, J. (1994). A class of tests for linkage using affected pedigree members. Biometrics, 50, 118-127.
    • (1994) Biometrics , vol.50 , pp. 118-127
    • Whittemore, A.S.1    Halpern, J.2


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