Transcriptional activation of the testis-specific histone H1t gene by RFX2 may require both proximal promoter X-box elements

Journal of Cellular Biochemistry

Volumn 94, Issue 2, 2005, Pages 317-326

  Grimes, Sidney R ^a,b   Prado, Susan ^a   Wolfe, Steven A ^a,b  

^a OVERTON BROOKS VA MEDICAL CENTER   (United States)

^b LOUISIANA STATE UNIVERSITY   (United States)

Author keywords

DNA binding proteins; Gene regulation; Histone H1t gene; RFX2; Tissue specific transcription

Indexed keywords

HISTONE H1; PALINDROMIC DNA; REGULATORY FACTOR X; REGULATORY FACTOR X2; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; HISTONE;

AFFINITY CHROMATOGRAPHY; ANIMAL CELL; ARTICLE; CONSENSUS SEQUENCE; CONTROLLED STUDY; GENE; GENE CONTROL; GENE MUTATION; GENETIC TRANSCRIPTION; HISTONE H1T GENE; MALE; NONHUMAN; NUCLEOTIDE REPEAT; PACHYTENE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; RAT; REPORTER GENE; SPERMATOCYTE; SPERMATOGENESIS; TESTIS; TRANSCRIPTION INITIATION; TRANSGENIC MOUSE; X BOX ELEMENT; ANIMAL; CELL CULTURE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOLECULAR GENETICS; MUTATION; NUCLEOTIDE SEQUENCE; REGULATORY SEQUENCE;

MUS MUSCULUS;

ANIMALS; BASE SEQUENCE; CELLS, CULTURED; CONSERVED SEQUENCE; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; HISTONES; MALE; MOLECULAR SEQUENCE DATA; MUTATION; PROMOTER REGIONS (GENETICS); RATS; REGULATORY SEQUENCES, NUCLEIC ACID; TESTIS; TRANSCRIPTION, GENETIC;

EID: 18444416838     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcb.20320     Document Type: Article

References (40)

1. Clare SE, Fantz DA, Kistler WS, Kistler MK. 1997. The testis-specific histone H1t gene is strongly repressed by a G/C-rich region just downstream of the TATA box. J Biol Chem 272:33028-33036.
2. Dignam JD, Lebovitz RM, Roeder RG. 1983. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res 11:1475-1489.
3. Dimberg J, Hugander A, Hall-Karlsson BM, Sirsjo A. 2002. RFX-B, a MHC class II transcription factor, suppressed in human colorectal adenocarcinomas. Int J Mol Med 9:213-216.
4. Dotzlaw H, Alkhalaf M, Murphy LC. 1992. Characterization of estrogen receptor variant mRNAs from human breast cancers. Mol Endocrinol 6:773-785.
5. Doyle J, Hoffman S, Ucla C, Reith W, Mach B, Stubbs L. 1996. Locations of human and mouse genes encoding the RFX1 and RFX2 transcription factor proteins. Genomics 35:227-230.
6. Drabent B, Doenecke D. 1997. Testis-specific expression of the mouse histone gene H1t is regulated by several promoter elements. Biol Reprod 57:1375-1383.
7. Durand B, Vandaele C, Spencer D, Pantalacci S, Couble P. 2000. Cloning and characterization of dRFX, the Drosophila member of the RFX family of transcription factors. Gene 246:285-293.
8. Emery P, Durand B, Mach B, Reith W. 1996. RFX proteins, a novel family of DNA binding proteins conserved in the eukaryotic kingdom. Nucleic Acids Res 24:803-807.
9. Gajiwala KS, Chen H, Cornille F, Roques BP, Reith W, Mach B, Burley SK. 2000. Structure of the winged-helix protein hRFX1 reveals a new mode of DNA binding. Nature 403:916-921.
10. Grimes SR. 2004. Testis-specific transcriptional control. Gene (in press).
11. Grimes SR, Wolfe SA, Anderson JV, Stein GS, Stein JL. 1990. Structural and functional analysis of the rat testis-specific histone H1t gene. J Cell Biochem 44:1-17.
12. Grimes SR, Wolfe SA, Koppel DA. 1992a. Temporal correlation between the appearance of testis-specific DNA-binding proteins and the onset of transcription of the testis-specific histone H1t gene. Exp Cell Res 201:216-224.
13. Grimes SR, Wolfe SA, Koppel DA. 1992b. Tissue-specific binding of testis nuclear proteins to a sequence element within the promoter of the testis-specific histone H1t gene. Arch Biochem Biophys 296:402-409.
14. Grimes SR, Wilkerson DC, Noss KR, Wolfe SA. 2003. Transcriptional control of the testis-specific histone H1t gene. Gene 304:13-21.
15. Hagen G, Muller S, Beato M, Suske G. 1994. Sp1-mediated transcriptional activation is repressed by Sp3. Embo J 13:3843-3851.
16. Hofmann MC, Hess RA, Goldberg E, Millan JL. 1994. Immortalized germ cells undergo meiosis in vitro. Proc Natl Acad Sci USA 91:5533-5537.
17. Hooper JD, Bowen N, Marshall H, Cullen LM, Sood R, Daniels R, Stuttgen MA, Normyle JF, Higgs DR, Kastner DL, Ogbourne SM, Pera MF, Jazwinska EC, Antalis TM. 2000. Localization, expression and genomic structure of the gene encoding the human serine protease testisin. Biochim Biophys Acta 1492:63-71.
18. Horvath GC, Kistler WS, Kistler MK. 2004. RFX2 is a potential transcriptional regulatory factor for histone H1t and other genes expressed during the meiotic phase of spermatogenesis. Biol Reprod (in press).
19. Huang M, Zhou Z, Elledge SJ. 1998. The DNA replication and damage checkpoint pathways induce transcription by inhibition of the Crt1 repressor. Cell 94:595-605.
20. Iwama A, Pan J, Zhang P, Reith W, Mach B, Tenen DG, Sun Z. 1999. Dimeric RFX proteins contribute to the activity and lineage specificity of the interleukin-5 receptor alpha promoter through activation and repression domains. Mol Cell Biol 19:3940-3950.
21. Masternak K, Reith W. 2002. Promoter-specific functions of CIITA and the MHC class II enhanceosome in transcriptional activation. Embo J 21:1379-1388.
22. Moreno CS, Rogers EM, Brown JA, Boss JM. 1997. Regulatory factor X, a bare lymphocyte syndrome transcription factor, is a multimeric phosphoprotein complex. J Immunol 158:5841-5848.
23. Morotomi-Yano K, Yano K, Saito H, Sun Z, Iwama A, Miki Y. 2002. Human regulatory factor X 4 (RFX4) is a testis-specific dimeric DNA-binding protein that cooperates with other human RFX members. J Biol Chem 277:836-842.
24. Osley MA. 1991. The regulation of histone synthesis in the cell cycle. Ann Rev Biochem 60:827-861.
25. Razin A. 1998. CpG methylation, chromatin structure and gene silencing-a three-way connection. Embo J 17:4905-4908.
26. Reith W, Ucla C, Barras E, Gaud A, Durand B, Herrero-Sanchez C, Kobr M, Mach B. 1994. RFX1, a transactivator of hepatitis B virus enhancer I, belongs to a novel family of homodimeric and heterodimeric DNA-binding proteins. Mol Cell Biol 14:1230-1244.
27. Schmitt EK, Kuck U. 2000. The fungal CPCR1 protein, which binds specifically to beta-lactam biosynthesis genes, is related to human regulatory factor X transcription factors. J Biol Chem 275:9348-9357.
28. Singal R, vanWert J, Bashambu M, Wolfe SA, Wilkerson DC, Grimes SR. 2000. Testis-specific histone H1t gene is hypermethylated in nongerminal cells in the mouse. Biol Reprod 63:1237-1244.
29. Swoboda P, Adler HT, Thomas JH. 2000. The RFX-type transcription factor DAF-19 regulates sensory neuron cilium formation in C. elegans. Mol Cell 5:411-421.
30. vanWert JM, Wolfe SA, Grimes SR. 1995. Testis-specific expression of the rat histone Hit gene in transgenic mice. Biochemistry 34:8733-8743.
31. vanWert JM, Panek HR, Wolfe SA, Grimes SR. 1998. The TE promoter element of the histone H1t gene is essential for transcription in primary spermatocytes. Biol Reprod 704-710.
32. Wade PA, Gegonne A, Jones PL, Ballestar E, Aubry F, Wolffe AP. 1999. Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacetylation. Nat Genet 23:62-66.
33. Warburg O, Christian W. 1942. Isolierung und Kristallisation des Garungsferments Enolase. Biochem Z 310:384-414.
34. Wilkerson DC, Wolfe SA, Grimes SR. 2002a. H1t/GC-box and H1t/TE1 element are essential for promoter activity of the testis-specific histone H1t gene. Biol Reprod 67:1157-1164.
35. Wilkerson DC, Wolfe SA, Grimes SR. 2002b. Sp1 and Sp3 activate the testis-specific histone H1t promoter through the H1t/GC-box. J Cell Biochem 86:716-725.
36. Wilkerson DC, Wolfe SA, Grimes SR. 2003. Functional differences in the TE1 and TE2 subelements of the testis-specific histone H1t promoter. J Cellular Biochemistry 88:1177-1187.
37. Wolfe SA, Grimes SR. 1999. Binding of nuclear proteins to an upstream element involved in transcriptional regulation of the testis-specific histone H1t gene. J Cell Biochem 75:555-565.
38. Wolfe SA, van Wert JM, Grimes SR. 1995. Expression of the testis-specific histone H1t gene: Evidence for involvement of multiple cis-acting promoter elements. Biochemistry 34:12461-12469.
39. Wolfe SA, Mottram PJ, vanWert JM, Grimes SR. 1999. Localization of upstream elements involved in transcriptional regulation of the rat testis-specific histone H1t gene in somatic cells. Biol Reprod 61:1005-1011.
40. Wolfe SA, Wilkerson DC, Prado S, Grimes SR. 2004. Regulatory factor X2 (RFX2) binds to the H1t/TE1 promoter element and activates transcription of the testis-specific histone H1t gene. J Cell Biochem 91:375-383.