Protein-kinase a and human disease: The core of cAMP-dependent signaling in health and disease

Hormone and Metabolic Research

Volumn 34, Issue 4, 2002, Pages 169-175

  Stratakis, C A ^a   Miller, W R ^a   Severin, E ^a   Chin, K V ^a   Bertherat, J ^a   Amieux, P S ^a   Eng, C ^a   Kammer, G M ^a   Dumont, J E ^a   Tortora, G ^a   Beaven, M A ^a   Puck, T T ^a   Jan de Beur, S M ^a   Weistein, L S ^a   Cho Chung, Y S ^a  

^a Building 10   (United States)

Author keywords

Carney Complex; Chromosome 17; Endocrine Tumors; G Proteins; Multiple Endocrine Neoplasia; Oncogene; Protein Kinase A; Regulatory Subunits; Tumor Suppressor Gene

Indexed keywords

CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; GUANINE NUCLEOTIDE BINDING PROTEIN;

CARCINOGENESIS; CARNEY COMPLEX; ENZYME MECHANISM; GENE CONTROL; GENE FUNCTION; GENETIC CODE; HUMAN; INHERITANCE; MULTIPLE ENDOCRINE NEOPLASIA; ONCOGENE; PATHOGENESIS; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR GENE;

EID: 18444408096     PISSN: 00185043     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2002-26710     Document Type: Review

References (6)

1. The role of cAMP in regulating tumour cell growth
2. The cyclic AMP-mediated stimulation of cell proliferation
3. An essential role for cyclic AMP in growth control: The case for yeast
4. Clinical and molecular features of the Carney complex: Diagnostic criteria and recommendations for patient evaluation
5. Genetic heterogeneity and spectrum of mutations of the PRKAR1A gene in patients with the Carney complex
6. Mutations of the gene encoding the protein kinase A type 1-alpha regulatory subunit in patients with the Carney complex