Role for c-jun N-terminal kinase in treatment-refractory acute myeloid leukemia (AML): Signaling to multidrug-efflux and hyperproliferation

Leukemia

Volumn 16, Issue 5, 2002, Pages 799-812

  Cripe, L D ^a   Gelfanov, V M ^a   Smith, E A ^b   Spigel, D R ^a   Phillips, C A ^a   Gabig, T G ^a   Jung, S H ^a   Fyffe, J ^a   Hartman, A D ^b   Kneebone, P ^a   Mercola, D ^c   Burgess, G S ^a   Boswell, H Scott ^a,b,d  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b INDIANA UNIVERSITY   (United States)

^c SIDNEY KIMMEL CANCER CENTER   (United States)

^d RICHARD L ROUDEBUSH VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

AML; Multidrug resistance; Signaling

Indexed keywords

ABC TRANSPORTER; ACETYLCYSTEINE; ANTHRACYCLINE DERIVATIVE; CATALASE; CYTARABINE; DAUNORUBICIN; GLUTATHIONE TRANSFERASE; MULTIDRUG RESISTANCE PROTEIN 1; PROTEIN C JUN; SERINE; STRESS ACTIVATED PROTEIN KINASE; XENOBIOTIC AGENT;

ACUTE GRANULOCYTIC LEUKEMIA; ADULT; AMINO TERMINAL SEQUENCE; ARTICLE; CANCER THERAPY; CELL STRAIN HL 60; CHEMICAL ANALYSIS; CONTROLLED STUDY; CORRELATION ANALYSIS; DOWN REGULATION; DRUG SENSITIVITY; DRUG TARGETING; ENZYME ACTIVITY; GENE EXPRESSION; GENE MUTATION; GENETIC CONSERVATION; GENETIC TRANSFECTION; HOMEOSTASIS; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; LEUKOCYTOSIS; MAJOR CLINICAL STUDY; MULTIDRUG RESISTANCE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TRANSPORT; SENSITIVITY ANALYSIS; SIGNAL TRANSDUCTION; TREATMENT FAILURE; YEAST;

EID: 18444396889     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2402457     Document Type: Article

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