New insight into the pathophysiology of severe hypothyroidism in an infant with multiple hepatic hemangiomas

Journal of Pediatric Endocrinology and Metabolism

Volumn 18, Issue 5, 2005, Pages 511-514

  Ho, Josephine ^a   Kendrick, Victoria ^a   Dewey, Deborah ^a   Pacaud, Danièle ^a  

^a ALBERTA CHILDREN'S HOSPITAL   (Canada)

Author keywords

Reverse triiodothyronine; Thyroid replacement therapy; Thyroid stimulating hormone; Type 3 iodothyronine deiodinase

Indexed keywords

LIOTHYRONINE; PERTECHNETIC ACID TC 99M; PREDNISONE; THYROID HORMONE; THYROTROPIN; THYROXINE; THYROXINE DEIODINASE;

ARTICLE; CASE REPORT; CHILD BEHAVIOR; CHILD DEVELOPMENT; COMPUTER ASSISTED TOMOGRAPHY; DISEASE SEVERITY; ENZYME ACTIVITY; EUTHYROIDISM; FEMALE; HEPATOMEGALY; HORMONE SUBSTITUTION; HORMONE SYNTHESIS; HUMAN; HYPOTHYROIDISM; INFANT; INFANT DISEASE; LIVER HEMANGIOMA; MULTIPLE CANCER; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; THYROID FUNCTION TEST; THYROID SCINTISCANNING;

EID: 18444384820     PISSN: 0334018X     EISSN: None     Source Type: Journal    
DOI: 10.1515/JPEM.2005.18.5.511     Document Type: Article

References (15)

1. Huang SA, Tu HM, Harney JW, Venihaki M, Butte AJ, Kozakewich HP, Fishman SJ, Larsen PR. Severe hypothyroidism caused by type 3 iodothyronine deiodinase in infantile hemangiomas. N Engl J Med 2000; 343: 185-189.
2. Ayling RM, Davenport M, Hadzic N, Metcalfe R, Howard ER, Mieli-Vergani G. Hepatic hemangioendothelioma associated with production of humoral thyrotropin-like factor. J Pediatr 2001; 138: 932-935.
3. Drolet BA, Esterly NB, Frieden IJ. Hemangiomas in children. N Engl J Med 1999; 341: 173-181.
4. Konrad D, Ellis G, Perlman K. Spontaneous regression of severe acquired infantile hypothyroidism associated with multiple liver hemangiomas. Pediatr Res 2001; 49: 156A.
5. Bayley N. Bayley Scales of Infant Development, 2nd Ed. San Antonio, TX: Psychological Corp., 1993.
6. Fishman SJ, Muliken JB. Hemangiomas and vascular malformations of infancy and childhood. Pediatr Clin North Am 1993; 40:1177-1200.
7. Griffin JE, Ojeda SR. The Textbook of Endocrine Physiology, 2nd Ed. Oxford: Oxford University Press, 1992; 224-246.
8. Bramswig JH, Werner C, Lengerke HJ, Micke O, Hesselmann S. Successful treatment of severe hypothyroidism in hepatic hemangioma. Pediatr Res 2001; 49: 155A.
9. LaFranchi A. Congenital hypothroidism: etiologies, diagnosis and management. Thyroid 1999; 9: 735-740.
10. Derksen-Lubsem G, Verkerk PH. Neuropsychologic development in early treated congenital hypothyroidism: analysis of literature data. Pediatr Res 1996; 39: 561-566.
11. Fuggle PW, Grant DB, Smith I, Murphy G. Intelligence, motor skills and behaviour at 5 years in early-treated congential hypothroidism. Eur J Pediatr 1991; 150: 570-574.
12. Kooistra L, Laane C, Vulsma T, Schellekens J, van der Meere J, Kalverboer A. Motor and cognitive development in children with congenital hypothyroidism: a long-term evaluation of the effects of neonatal treatment. J Pediatr 1994; 124: 903-909.
13. Kooistra L, van der Meere JJ, Vulsma T, Kalverboer AF. Sustained attention problems in children with early treated congenital hypothyroidism. Acta Paediatr 1996; 85: 425-429.
14. Rovet J, Alvarez M. Thyroid hormone and attention in school-age children with congenital hypothyroidism. J Child Psychol Psychiat 1996; 37: 579-585.
15. Rovet J, Hepworth S. Attention problems in adolescents with congential hypothroidism: a multicomponential analysis. J Int Neurosychol Soc 2001; 7: 734-744.