Chemo-enzymatic synthesis of both enantiomers of the anti-anginal drug ranolazine

Biocatalysis and Biotransformation

Volumn 23, Issue 1, 2005, Pages 45-51

  Moen, Anders Riise ^a   Karstad, Rasmus ^a   Anthonsen, Thorleif ^a  

^a NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

Author keywords

Angina; Candida antarctica; Capillary electrophoresis; Chiral analysis; Highly sulfated cyklodextrins; Kinetic resolution; Ranexa; Ranolazine; Rhizomucor miehei; Stereoinversion

Indexed keywords

ALCOHOLS; CATALYSIS; DRUG PRODUCTS; SYNTHESIS (CHEMICAL);

ANTI-ANGINAL DRUG RANOLAZINE; CHEMO-ENZYMATIC SYNTHESIS; ENANTIOMERS; KINETIC RESOLUTION; STEREOINVERSION REACTIONS;

ENZYMES;

ANTIANGINA PECTORIS AGENT; CYCLODEXTRIN; LIPASE B; RANOLAZINE; TRIACYLGLYCEROL LIPASE;

ANGINA PECTORIS; ARTICLE; CANDIDA ANTARCTICA; CAPILLARY ELECTROPHORESIS; CARBON NUCLEAR MAGNETIC RESONANCE; CATALYST; CHIRAL CHROMATOGRAPHY; DRUG INHIBITION; DRUG MECHANISM; DRUG POTENTIATION; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOMER; FATTY ACID OXIDATION; HUMAN; HYDROLYSIS; KINETICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RACEMIC MIXTURE; RHIZOMUCOR; RHIZOMUCOR MIEHEI; TRANSESTERIFICATION;

ANGINA; CANDIDA ANTARCTICA; RHIZOMUCOR MIEHEI;

EID: 18444378456     PISSN: 10242422     EISSN: None     Source Type: Journal    
DOI: 10.1080/10242420500067357     Document Type: Article

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