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Volumn 10, Issue 8, 2002, Pages 2779-2793

Synthesis and in vitro platelet aggregation and TP receptor binding studies on bicyclic 5,8-ethanooctahydroisoquinolines and 5,8-ethanotetrahydroisoquinolines

(10) Saha, Shankar L a Roche, Victoria F a Pendola, Kathleen a Kearley, Mark a Lei, Longping b Romstedt, Karl J c,d Herdman, Mark c,d Shams, Gamal c Kaisare, Vivek b Feller, Dennis R b,c

a CREIGHTON UNIVERSITY (United States)

b UNIVERSITY OF MISSISSIPPI (United States)

c OHIO STATE UNIVERSITY (United States)

d CAPITAL UNIVERSITY (United States)

Author keywords

[No Author keywords available]

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; 5,8 ETHANO 1 (3,4,5 TRIMETHOXYBENZYL) 1,2,3,4,5,6,7,8 OCTAHYDROISOQUINOLINE; 5,8 ETHANO 1 (3,4,5 TRIMETHOXYBENZYL) 5,6,7,8 TETRAHYDROISOQUINOLINE; 5,8 ETHANO 1 (4 CHLOROBENZYL) 1,2,3,4,5,6,7,8 OCTAHYDROISOQUINOLINE; 5,8 ETHANO 1 (4 CHLOROBENZYL) 2 (4 METHOXYBENZYL) 1,2,3,4,5,6,7,8 OCTAHYDROISOQUINOLINE; 5,8 ETHANO 1 (4 CHLOROBENZYL) 2 METHYL 1,2,3,4,5,6,7,8 OCTAHYDROISOQUINOLINE; 5,8 ETHANO 1 (4 CHLOROBENZYL) 2,2 DIMETHYL 1,2,3,4,5,6,7,8 OCTAHYDROISOQUINOLINE IODIDE; 5,8 ETHANO 1 (4 CHLOROBENZYL) 5,6,7,8 TETRAHYDROISOQUINOLINE; 5,8 ETHANO 1 (4 METHOXYBENZYL) 1,2,3,4,5,6,7,8 OCTAHYDROISOQUINOLINE; 5,8 ETHANO 1 (4 METHOXYBENZYL) 5,6,7,8 TETRAHYDROISOQUINOLINE; 5,8 ETHANO 1 (4 METHYLBENZYL) 1,2,3,4,5,6,7,8 OCTAHYDROISOQUINOLINE; 5,8 ETHANO 1 (4 METHYLBENZYL) 5,6,7,8 TETRAHYDROISOQUINOLINE; 5,8 ETHANO 1,2 DI (4 METHOXYBENZYL) 1,2,3,4,5,6,7,8 OCTAHYDROISOQUINOLINE; 5,8 ETHANO 2 (4 METHOXYBENZYL) 1 (3,4,5 TRIMETHOXYBENZYL) 1,2,3,4,5,6,7,8 OCTAHYDROISOQUINOLINE; 5,8 ETHANO 2 (4 METHOXYBENZYL) 1 (4 METHYLBENZYL) 1,2,3,4,5,6,7,8 OCTAHYDROISOQUINOLINE; 5,8 ETHANO 2 FORMYL 1 (4 CHLOROBENZYL) 1,2,3,4,5,6,7,8 OCTAHYDROISOQUINOLINE; 5,8 ETHANO 2 METHYL 1 (3,4,5 TRIMETHOXYBENZYL) 1,2,3,4,5,6,7,8 OCTAHYDROISOQUINOLINE; 5,8 ETHANO 2 METHYL 1 (4 METHYLBENZYL) 1,2,3,4,5,6,7,8 OCTAHYDROISOQUINOLINE; 7 [3 [(4 PHENYLSEMICARBAZIDO)METHYL] 7 OXABICYCLO[2.2.1]HEPT 2 YL] 5 HEPTENOIC ACID; ISOQUINOLINE DERIVATIVE; UNCLASSIFIED DRUG; ANTITHROMBOCYTIC AGENT; FUSED HETEROCYCLIC RINGS; PROSTAGLANDIN RECEPTOR; THROMBOXANE A2 RECEPTOR; THROMBOXANE RECEPTOR;

ARTICLE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; OXIDATION; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION; THROMBOCYTE AGGREGATION; DRUG ANTAGONISM; DRUG EFFECT; IC 50; PROTEIN BINDING; SYNTHESIS;

BICYCLO COMPOUNDS, HETEROCYCLIC; HUMANS; INHIBITORY CONCENTRATION 50; ISOQUINOLINES; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; PROTEIN BINDING; RECEPTORS, PROSTAGLANDIN; RECEPTORS, THROMBOXANE; RECEPTORS, THROMBOXANE A2, PROSTAGLANDIN H2; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 18444366474 PISSN: 09680896 EISSN: None Source Type: Journal
DOI: 10.1016/S0968-0896(02)00101-3 Document Type: Article

Times cited : (10)

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