Presence of prolonged dispersion of QT intervals in late survivors of childhood anthracycline therapy

Pediatric Hematology and Oncology

Volumn 19, Issue 8, 2002, Pages 533-542

  Gupta, Monesha ^a,b,c   Thaler, Howard T ^a   Steinherz, Laurel ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b NEW YORK PRESBYTERIAN HOSPITAL   (United States)

^c UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Anthracyclines; Electrocardiogram; QT dispersion; Sudden death

Indexed keywords

ANTHRACYCLINE;

ADOLESCENT; ARTICLE; CARDIOTOXICITY; CHILDHOOD CANCER; ELECTROCARDIOGRAM; FEMALE; HEART ARRHYTHMIA; HEART DEATH; HEART FAILURE; HEART MUSCLE INJURY; HEART VENTRICLE ARRHYTHMIA; HUMAN; INCIDENCE; LONG QT SYNDROME; MAJOR CLINICAL STUDY; MALE; QT INTERVAL; SCHOOL CHILD; SUDDEN DEATH; SURVIVAL; ADULT; AUTOPSY; BLOOD DISEASE; CASE CONTROL STUDY; CHEMICALLY INDUCED DISORDER; CHILD; ELECTROCARDIOGRAPHY; MIDDLE AGED; RETROSPECTIVE STUDY; RISK FACTOR; SURVIVOR;

ADOLESCENT; ADULT; ANTHRACYCLINES; ARRHYTHMIA; AUTOPSY; CASE-CONTROL STUDIES; CHILD; DEATH, SUDDEN, CARDIAC; ELECTROCARDIOGRAPHY; FEMALE; HEMATOLOGIC NEOPLASMS; HUMANS; LONG QT SYNDROME; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; RISK FACTORS; SURVIVORS;

EID: 1842865962     PISSN: 08880018     EISSN: None     Source Type: Journal    
DOI: 10.1080/08880010290097387     Document Type: Article

References (25)

1. Steinherz L, Steinherz P. Delayed cardiac toxicity from anthracycline therapy. Pediatrician. 1991; 18:49-52.
2. Steinherz LJ, Steinberz PG, Tan CTC, Heller G, Murphy L. Cardiac toxicity 4 to 20 years after completing anthracycline therapy. JAMA. 1991;266:1672-1677.
3. Bender KS, Shematek JP, Leventhal BG, Kan JS. QT interval prolongation associated with anthracycline cardiotoxicity. J Pediatr. 1984;105:442-444.
4. Schouten EG, Dekker JM, Meppelink P, Kok FJ, Vandenbrouke JP, Pool J. QT-interval prolongation predicts cardiovascular mortality in an apparently healthy population. Circulation. 1991;84:1516-1523.
5. Algra A, Tijessen JGP, Roelandt JRTC, Pool J, Lubsen J. QTc prolongation measured by standard 12 lead electrocardiogram is an independent risk factor for sudden death due to cardiac arrest. Circulation. 1991;83:1888-1894.
6. Vloka ME, Steinherg JS. QT dispersion: Current and future clinical role. J Invas Cardiol. 1996;8:363-369.
7. Buja G, Miorelli M, Turrini P, Melacini P, Nava A. Comparison of QT dispersion in hypertrophic cardiomyopathy between patients with and without ventricular arrhythmias and sudden death. Am J Cardiol. 1993;72:973-976.
8. Perkioaki JS, Koistinen MJ, Yli-Mayry S, Huikuri HV. Dispersion of QT interval in patients with and without susceptibility to ventricular tachyarrhythmias after previous myocardial infarction. J Am Coll Cardiol. 1995;26:174-179.
9. Barr CS, Naas A, Freeman M, Lang CC, Struthers AD. QT dispersion and sudden expected death in chronic heart failure. Lancet. 1994;343:327-329.
10. Zareba W, Moss AJ, le Cessie S. Dispersion of ventricular repolarization and arrhythmic cardiac death in coronary artery disease. Am J Cardiol. 1994;74:550.
11. Yamada T, Fukunami M, Shimonagata T, et al. Anatomical basis of QT dispersion in patients with dilated cardiomyopathy. Circulation. 1998;98(17):I-441 (abstract).
12. Bazett HC. An analysis of time relationships of the heart. Heart. 1920;7:353-370.
13. Moss AJ. Measurement of the QT interval and the risk associated with QTc interval prolongation: A review. Am J Cardiol. 1993;72:23B-25B.
14. Schwartz PJ, Moss AJ, Vincent GM, Crampton RS. Diagnostic criteria for the long QT syndrome - An update. Circulation. 1993;88:782-784.
15. Buja G. Comment in: Pacing Clin Electrophysiol. 1994;17(11 Pt 1):1833-1835.
16. Kautzner J, Yi G, Camm AJ, Malik M. Short- and long-term reproducibility of QT, QTc, and QT dispersion measurement in healthy subjects. PACE. 1994;17:928-937.
17. Linker NJ, Colonna P, Kekwick CA, Till J, Camm J, Ward DE. Assessment of QT dispersion in symptomatic patients with congenital long QT syndromes. Cardiol Am J Cardiol. 69:634-638.
18. Zaidi M, Robert AR, Fesler R, Derwael C, De Kock M, Brohet CR. Computer-assisted study of ECG Indices of the dispersion of ventricular repolarization. J Electrocardiol. 1996;29:199-211.
19. Steinherz LJ, Graham T, Hurwitz R, et al. Guidelines for monitoring of children during and after anthracycline therapy: Report of the cardiology committee of the Childrens Cancer Study Group. Pediatrics. 1992;89(5 Pt I):942-949.
20. Ritchie JL, Singer JW, Thorning D, Sorensen SG, Hamilton GW. Anthracycline cardiotoxicity: clinical and pathologic outcomes assessed by radionuclide ejection fraction. Cancer. 1980;46:1109-1116.
21. Couch RD, Loh KK, Sugino J. Sudden cardiac death following adriamycin therapy. Cancer. 1981;48: 38-39.
22. Nousiainen T, Vanninen E, Rantala A, Jantunen E, Hartikainen J. QT dispersion and late potentials during doxorubicin therapy for non-Hodgkin's lymphoma. J Intern Med. 1999;245:359-364.
23. Gonzalez-Juanatey JR, Garcia-Acuna JM, Pose A, et al. Reduction of QT and QTc dispersion during long-term treatment of systemic hypertension with enalapril. Am J Cardiol. 1998;81:170-174.
24. Barr CS, Naas AA, Fenwick M, Struthers AD. Enalapril reduces QTc dispersion in mild congestive heart failure secondary to coronary artery disease. Am J Cardiol. 1997;79:328-333.
25. Day CP, McComb JM, Matthews J, Campbell RWF. Reduction in QT dispersion by sotalol following myocardial infarction. Eur Heart J. 1991;12:423-427.