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Volumn 10, Issue 2, 2004, Pages 89-126

Current Debates in Antiphospholipid Syndrome: The Acquired Antibody-Mediated Thrombophilia

Author keywords

Anticardiolipin antibodies; Antiphospholipid antibodies; Antiphospholipid antibody syndrome; Clinical features; Laboratory investigation; Lupus anticoagulants; Management; Pathobiology; Terminology

Indexed keywords

ACETYLSALICYLIC ACID; ANTIBODY; ANTICOAGULANT AGENT; ANTIOXIDANT; AUTOANTIBODY; BETA2 GLYCOPROTEIN 1; CARDIOLIPIN ANTIBODY; CHLOROQUINE; CLOPIDOGREL; CYCLOPHOSPHAMIDE; CYCLOSPORIN A; DALTEPARIN; DANAZOL; DAPSONE; ENOXAPARIN; FIBRINOLYTIC AGENT; HEPARIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IMMUNOGLOBULIN; LJP 1082; LOW MOLECULAR WEIGHT HEPARIN; LUPUS ANTICOAGULANT; PHOSPHOLIPID ANTIBODY; PREDNISONE; RECOMBINANT TISSUE FACTOR PATHWAY INHIBITOR; STEROID; UNCLASSIFIED DRUG; WARFARIN;

EID: 1842863095     PISSN: 10760296     EISSN: None     Source Type: Journal    
DOI: 10.1177/107602960401000201     Document Type: Review
Times cited : (20)

References (385)
  • 2
    • 0033035842 scopus 로고    scopus 로고
    • Lupus anticoagulant testing in Europe: An analysis of results from the first European Concerted Action on Thrombophilia (ECAT) survey using plasmas spiked with monoclonal antibodies against human beta2-glycoprotein I
    • Arnout J, Meijer P, Vermylen J. Lupus anticoagulant testing in Europe: An analysis of results from the first European Concerted Action on Thrombophilia (ECAT) survey using plasmas spiked with monoclonal antibodies against human beta2-glycoprotein I. Thromb Haemost 1999;81:929.
    • (1999) Thromb Haemost , vol.81 , pp. 929
    • Arnout, J.1    Meijer, P.2    Vermylen, J.3
  • 3
    • 0025302635 scopus 로고
    • Anticardiolipin antibodies (ACA) directed not to cardiolipin but to a plasma protein cofactor
    • Galli M, Comfurius P, Maassen C, et al. Anticardiolipin antibodies (ACA) directed not to cardiolipin but to a plasma protein cofactor. Lancet 1990;335:1544.
    • (1990) Lancet , vol.335 , pp. 1544
    • Galli, M.1    Comfurius, P.2    Maassen, C.3
  • 4
    • 0025951058 scopus 로고
    • Lupus anticoagulant IgG's (LA) are not directed to phospholipids only, but to a complex of lipid-bound human prothrombin
    • Bevers EM, Galli M, Barbui T, et al. Lupus anticoagulant IgG's (LA) are not directed to phospholipids only, but to a complex of lipid-bound human prothrombin. Thromb Haemost 1991;66:629.
    • (1991) Thromb Haemost , vol.66 , pp. 629
    • Bevers, E.M.1    Galli, M.2    Barbui, T.3
  • 5
    • 0026726648 scopus 로고
    • Lupus anticoagulant activity of autoimmune antiphospholipid antibodies is dependent upon beta 2-glycoprotein I
    • Roubey RA, Pratt CW, Buyon JP, et al. Lupus anticoagulant activity of autoimmune antiphospholipid antibodies is dependent upon beta 2-glycoprotein I. J Clin Invest 1992;90:1100.
    • (1992) J Clin Invest , vol.90 , pp. 1100
    • Roubey, R.A.1    Pratt, C.W.2    Buyon, J.P.3
  • 6
    • 0026581189 scopus 로고
    • Lupus anticoagulant activity is frequently dependent on the presence of beta2-glycoprotein I
    • Oosting JD, Derksen RH, Entjes HT, et al. Lupus anticoagulant activity is frequently dependent on the presence of beta2-glycoprotein I. Thromb Haemost 1992;67:499.
    • (1992) Thromb Haemost , vol.67 , pp. 499
    • Oosting, J.D.1    Derksen, R.H.2    Entjes, H.T.3
  • 7
    • 0027987114 scopus 로고
    • Autoantibodies to phospholipid-binding plasma proteins: A new view of lupus anticoagulants and other "antiphospholipid" autoantibodies
    • Roubey RA. Autoantibodies to phospholipid-binding plasma proteins: A new view of lupus anticoagulants and other "antiphospholipid" autoantibodies. Blood 1994;84:2854.
    • (1994) Blood , vol.84 , pp. 2854
    • Roubey, R.A.1
  • 8
    • 0028983571 scopus 로고
    • "Anticardiolipin" autoantibodies recognize beta 2-glycoprotein I in the absence of phospholipid. Importance of Ag density and bivalent binding
    • Roubey RA, Eisenberg RA, Harper MF, et al. "Anticardiolipin" autoantibodies recognize beta 2-glycoprotein I in the absence of phospholipid. Importance of Ag density and bivalent binding. J Immunol 1995;154:954.
    • (1995) J Immunol , vol.154 , pp. 954
    • Roubey, R.A.1    Eisenberg, R.A.2    Harper, M.F.3
  • 9
    • 0028158771 scopus 로고
    • Anticardiolipin antibodies recognize beta 2-glycoprotein I structure altered by interacting with an oxygen modified solid phase surface
    • Matsuura E, Igarashi Y, Yasuda T, et al. Anticardiolipin antibodies recognize beta 2-glycoprotein I structure altered by interacting with an oxygen modified solid phase surface. J Exp Med 1994;179:457.
    • (1994) J Exp Med , vol.179 , pp. 457
    • Matsuura, E.1    Igarashi, Y.2    Yasuda, T.3
  • 10
    • 0032529194 scopus 로고    scopus 로고
    • Anti-beta 2-glycoprotein I autoantibodies from patients with the "antiphospholipid" syndrome bind to beta 2-glycoprotein I with low affinity: Dimerization of beta 2-glycoprotein I induces a significant increase in anti-beta 2-glycoprotein I antibody affinity
    • Sheng Y, Kandiah DA, Krilis SA. Anti-beta 2-glycoprotein I autoantibodies from patients with the "antiphospholipid" syndrome bind to beta 2-glycoprotein I with low affinity: Dimerization of beta 2-glycoprotein I induces a significant increase in anti-beta 2-glycoprotein I antibody affinity. J Immunol 1998;161:2038.
    • (1998) J Immunol , vol.161 , pp. 2038
    • Sheng, Y.1    Kandiah, D.A.2    Krilis, S.A.3
  • 11
    • 0028888610 scopus 로고
    • Autoimmune antiphospholipid antibodies are directed against a cryptic epitope expressed when beta 2-glycoprotein I is bound to a suitable surface
    • Pengo V, Biasiolo A, Fior MG. Autoimmune antiphospholipid antibodies are directed against a cryptic epitope expressed when beta 2-glycoprotein I is bound to a suitable surface. Thromb Haemost 1995;73:29.
    • (1995) Thromb Haemost , vol.73 , pp. 29
    • Pengo, V.1    Biasiolo, A.2    Fior, M.G.3
  • 12
    • 0033061811 scopus 로고    scopus 로고
    • Conformationally altered beta 2-glycoprotein I is the antigen for anti-cardiolipin antibodies
    • Chamley LW, Duncalf AM, Konarkowska B, et al. Conformationally altered beta 2-glycoprotein I is the antigen for anti-cardiolipin antibodies. Clin Exp Immunol 1999;11:571.
    • (1999) Clin Exp Immunol , vol.11 , pp. 571
    • Chamley, L.W.1    Duncalf, A.M.2    Konarkowska, B.3
  • 14
    • 0021749102 scopus 로고
    • Anticardiolipin antibodies and lupus anticoagulant
    • Harris EN, Loizou S, Englert H, et al. Anticardiolipin antibodies and lupus anticoagulant. Lancet 1984;ii:1099.
    • (1984) Lancet , vol.2 , pp. 1099
    • Harris, E.N.1    Loizou, S.2    Englert, H.3
  • 15
    • 0024294211 scopus 로고
    • The relationship between lupus anticoagulants and antibodies to phospholipid
    • Triplett DA, Brandt JT, Musgrave KA, et al. The relationship between lupus anticoagulants and antibodies to phospholipid. JAMA 1988;259:550.
    • (1988) JAMA , vol.259 , pp. 550
    • Triplett, D.A.1    Brandt, J.T.2    Musgrave, K.A.3
  • 16
    • 0025064328 scopus 로고
    • Correlation between lupus anticoagulants and anticardiolipin antibodies in patients with prolonged activated partial thromboplastin times
    • Alving BM, Barr CF, Tang DB. Correlation between lupus anticoagulants and anticardiolipin antibodies in patients with prolonged activated partial thromboplastin times. Am J Med 1990;88:112.
    • (1990) Am J Med , vol.88 , pp. 112
    • Alving, B.M.1    Barr, C.F.2    Tang, D.B.3
  • 17
    • 0030280337 scopus 로고    scopus 로고
    • The antiphospholipid/cofactor syndromes: A primary variant with antibodies to beta 2-glycoprotein-I but no antibodies detectable in standard antiphospholipid assays
    • Cabral AR, Amigo MC, Cabiedes J, et al. The antiphospholipid/cofactor syndromes: A primary variant with antibodies to beta 2-glycoprotein-I but no antibodies detectable in standard antiphospholipid assays. Am J Med 1996;101:472.
    • (1996) Am J Med , vol.101 , pp. 472
    • Cabral, A.R.1    Amigo, M.C.2    Cabiedes, J.3
  • 18
    • 0037322484 scopus 로고    scopus 로고
    • Antiphospholipid thrombosis syndromes
    • Bick RL. Antiphospholipid thrombosis syndromes. Hematol Oncol Clin North Am 2003;17:115.
    • (2003) Hematol Oncol Clin North Am , vol.17 , pp. 115
    • Bick, R.L.1
  • 20
    • 0030898808 scopus 로고    scopus 로고
    • Pathogenic antibodies in women with obstetric features of antiphospholipid syndrome who have negative test results for lupus anticoagulant and anticardiolipin antibodies
    • Silver RM, Pierangeli SS, Edwin SS, et al. Pathogenic antibodies in women with obstetric features of antiphospholipid syndrome who have negative test results for lupus anticoagulant and anticardiolipin antibodies. Am J Obstet Gynecol 1997;176:628.
    • (1997) Am J Obstet Gynecol , vol.176 , pp. 628
    • Silver, R.M.1    Pierangeli, S.S.2    Edwin, S.S.3
  • 21
    • 0034858553 scopus 로고    scopus 로고
    • Which antiphospholipid antibody tests are most useful?
    • Merrill JT. Which antiphospholipid antibody tests are most useful? Rheum Dis Clin North Am 2001;27:525.
    • (2001) Rheum Dis Clin North Am , vol.27 , pp. 525
    • Merrill, J.T.1
  • 22
    • 0033113371 scopus 로고    scopus 로고
    • Serum anti-beta2-glycoprotein-I and anticardiolipin antibodies during thrombosis in systemic lupus erythematosus patients
    • Gomez-Pacheco L, Villa AR, Drenkard C, et al. Serum anti-beta2-glycoprotein-I and anticardiolipin antibodies during thrombosis in systemic lupus erythematosus patients. Am J Med 1999;106:417.
    • (1999) Am J Med , vol.106 , pp. 417
    • Gomez-Pacheco, L.1    Villa, A.R.2    Drenkard, C.3
  • 23
    • 0036228886 scopus 로고    scopus 로고
    • Antiphospholipid syndrome: Clinical and immunologic manifestations and patterns of disease expression in a cohort of 1,000 patients
    • Euro-Phospholipid Project Group
    • Cervera R, Piette JC, Font J, et al. Euro-Phospholipid Project Group. Antiphospholipid syndrome: Clinical and immunologic manifestations and patterns of disease expression in a cohort of 1,000 patients. Arthritis Rheum 2002;46:1019.
    • (2002) Arthritis Rheum , vol.46 , pp. 1019
    • Cervera, R.1    Piette, J.C.2    Font, J.3
  • 24
    • 0025239836 scopus 로고
    • Antiphospholipid antibodies: Anticardiolipin and the lupus anticoagulant in systemic lupus erythematosus (SLE) and in non-SLE disorders
    • Love PE, Santoro SA. Antiphospholipid antibodies: Anticardiolipin and the lupus anticoagulant in systemic lupus erythematosus (SLE) and in non-SLE disorders. Ann Intern Med 1990;112:682.
    • (1990) Ann Intern Med , vol.112 , pp. 682
    • Love, P.E.1    Santoro, S.A.2
  • 25
    • 0024427029 scopus 로고
    • Antiphospholipid antibodies and the antiphospholipid syndrome in systemic lupus erythematosus. A prospective analysis of 500 consecutive patients
    • Alarcon-Segovia D, Deleze M, Oria CV, et al. Antiphospholipid antibodies and the antiphospholipid syndrome in systemic lupus erythematosus. A prospective analysis of 500 consecutive patients. Medicine (Baltimore) 1989;68:353.
    • (1989) Medicine (Baltimore) , vol.68 , pp. 353
    • Alarcon-Segovia, D.1    Deleze, M.2    Oria, C.V.3
  • 26
    • 0034779270 scopus 로고    scopus 로고
    • Antiphospholipid thrombosis syndromes
    • Bick RL. Antiphospholipid thrombosis syndromes. Clin Appl Thromb Hemost 2001;7:241.
    • (2001) Clin Appl Thromb Hemost , vol.7 , pp. 241
    • Bick, R.L.1
  • 27
  • 28
    • 0032769325 scopus 로고    scopus 로고
    • Antiphospholipid syndrome and thrombosis
    • Bick RL, Baker WF. Antiphospholipid syndrome and thrombosis. Semin Thromb Hemost 1999;25:333.
    • (1999) Semin Thromb Hemost , vol.25 , pp. 333
    • Bick, R.L.1    Baker, W.F.2
  • 29
    • 0025124929 scopus 로고
    • Cerebrovascular and neurologic disease associated with antiphospholipid antibodies: 48 Cases
    • Levine SR, Deegan MJ, Futrell N, et al. Cerebrovascular and neurologic disease associated with antiphospholipid antibodies: 48 cases. Neurology 1990;40:1181.
    • (1990) Neurology , vol.40 , pp. 1181
    • Levine, S.R.1    Deegan, M.J.2    Futrell, N.3
  • 30
    • 0026817042 scopus 로고
    • A phospholipid-beta 2-glycoprotein I complex is an antigen for anticardiolipin antibodies occurring in autoimmune disease but not with infection
    • Hunt JE, McNeil HP, Morgan GJ, et al. A phospholipid-beta 2-glycoprotein I complex is an antigen for anticardiolipin antibodies occurring in autoimmune disease but not with infection. Lupus 1992;1:75.
    • (1992) Lupus , vol.1 , pp. 75
    • Hunt, J.E.1    McNeil, H.P.2    Morgan, G.J.3
  • 31
    • 0035003656 scopus 로고    scopus 로고
    • Cofactor dependence and isotype distribution of anticardiolipin antibodies in viral infections
    • Guglielmone H, Vitozzi S, Elbarcha O, et al. Cofactor dependence and isotype distribution of anticardiolipin antibodies in viral infections. Ann Rheum Dis 2001;60:500.
    • (2001) Ann Rheum Dis , vol.60 , pp. 500
    • Guglielmone, H.1    Vitozzi, S.2    Elbarcha, O.3
  • 32
    • 0037405490 scopus 로고    scopus 로고
    • Antiphospholipid antibodies and infections
    • Asherson RA, Cervera R. Antiphospholipid antibodies and infections. Ann Rheum Dis 2003;62:388.
    • (2003) Ann Rheum Dis , vol.62 , pp. 388
    • Asherson, R.A.1    Cervera, R.2
  • 33
    • 0032752958 scopus 로고    scopus 로고
    • Hughes syndrome associated with cytomegalovirus infection
    • Uthman I, Tabbarah Z, Gharavi AE. Hughes syndrome associated with cytomegalovirus infection. Lupus 1999;8:775.
    • (1999) Lupus , vol.8 , pp. 775
    • Uthman, I.1    Tabbarah, Z.2    Gharavi, A.E.3
  • 34
    • 0031044766 scopus 로고    scopus 로고
    • Antiphospholipid syndrome associated with cytomegalovirus infection: Case report and review
    • Labarca JA, Rabaggliati RM, Radrigan FJ, et al. Antiphospholipid syndrome associated with cytomegalovirus infection: Case report and review. Clin Infect Dis 1997;24:197.
    • (1997) Clin Infect Dis , vol.24 , pp. 197
    • Labarca, J.A.1    Rabaggliati, R.M.2    Radrigan, F.J.3
  • 35
    • 6844236355 scopus 로고    scopus 로고
    • Autoantibodies directed against phospholipids or human beta 2-glycoprotein I in HIV-seropositive patients: Relationship with endothelial activation and antimalonic dialdehyde antibodies
    • Constans J, Guerin V, Couchouron A, et al. Autoantibodies directed against phospholipids or human beta 2-glycoprotein I in HIV-seropositive patients: Relationship with endothelial activation and antimalonic dialdehyde antibodies. Eur J Clin Invest 1998;28:115.
    • (1998) Eur J Clin Invest , vol.28 , pp. 115
    • Constans, J.1    Guerin, V.2    Couchouron, A.3
  • 36
    • 0036175471 scopus 로고    scopus 로고
    • Viral infections and antiphospholipid antibodies
    • Uthman IW, Gharavi AE. Viral infections and antiphospholipid antibodies. Semin Arthritis Rheum 2002;31:256.
    • (2002) Semin Arthritis Rheum , vol.31 , pp. 256
    • Uthman, I.W.1    Gharavi, A.E.2
  • 37
    • 0028168893 scopus 로고
    • Antiphospholipid antibodies in patients with idiopathic autoimmune haemolytic anemia
    • Guzman J, Cabral AR, Cabiedes J, et al. Antiphospholipid antibodies in patients with idiopathic autoimmune haemolytic anemia. Autoimmunity 1994;18:51.
    • (1994) Autoimmunity , vol.18 , pp. 51
    • Guzman, J.1    Cabral, A.R.2    Cabiedes, J.3
  • 38
    • 0037059463 scopus 로고    scopus 로고
    • Molecular pathogenesis of the antiphospholipid syndrome
    • Rand JH. Molecular pathogenesis of the antiphospholipid syndrome. Circ Res 2002;90:29.
    • (2002) Circ Res , vol.90 , pp. 29
    • Rand, J.H.1
  • 39
    • 0031597372 scopus 로고    scopus 로고
    • Anti-beta2-glycoprotein I, anti-prothrombin and anticardiolipin antibodies in a longitudinal study of patients with systemic lupus erythematosus and the antiphospholipid syndrome
    • Inanc M, Donohoe S, Ravirajan CT, et al. Anti-beta2-glycoprotein I, anti-prothrombin and anticardiolipin antibodies in a longitudinal study of patients with systemic lupus erythematosus and the antiphospholipid syndrome. Br J Rheumatol 1998;37:1089.
    • (1998) Br J Rheumatol , vol.37 , pp. 1089
    • Inanc, M.1    Donohoe, S.2    Ravirajan, C.T.3
  • 40
    • 0029953246 scopus 로고    scopus 로고
    • Natural history and risk factors for thrombosis in 360 patients with antiphospholipid antibodies: A four-year prospective study from the Italian Registry
    • Finazzi G, Brancaccio V, Moia M, et al. Natural history and risk factors for thrombosis in 360 patients with antiphospholipid antibodies: A four-year prospective study from the Italian Registry. Am J Med 1996;100:530.
    • (1996) Am J Med , vol.100 , pp. 530
    • Finazzi, G.1    Brancaccio, V.2    Moia, M.3
  • 41
    • 0026492990 scopus 로고
    • Anticardiolipin antibodies and the risk for ischemic stroke and venous thrombosis
    • Ginsburg KS, Liang MH, Newcomer L, et al. Anticardiolipin antibodies and the risk for ischemic stroke and venous thrombosis. Ann Intern Med 1992;117:997.
    • (1992) Ann Intern Med , vol.117 , pp. 997
    • Ginsburg, K.S.1    Liang, M.H.2    Newcomer, L.3
  • 42
    • 0027453679 scopus 로고
    • Anticardiolipin antibodies are an independent risk factor for first ischemic stroke
    • The Antiphospholipid Antibodies in Stroke Study (APASS) Group
    • Antiphospholipid Antibodies in Stroke Study Group. Anticardiolipin antibodies are an independent risk factor for first ischemic stroke. The Antiphospholipid Antibodies in Stroke Study (APASS) Group. Neurology 1993;43:2069.
    • (1993) Neurology , vol.43 , pp. 2069
  • 43
    • 0028850821 scopus 로고
    • Anti-cardiolipin antibodies and risk of myocardial infarction in a prospective cohort of middle-aged men
    • Vaarala O, Manttari M, Manninen V, et al. Anti-cardiolipin antibodies and risk of myocardial infarction in a prospective cohort of middle-aged men. Circulation 1995;91:23.
    • (1995) Circulation , vol.91 , pp. 23
    • Vaarala, O.1    Manttari, M.2    Manninen, V.3
  • 44
    • 0030874725 scopus 로고    scopus 로고
    • IgG anticardiolipin antibody titer >40 GPL and the risk of subsequent thrombo-occlusive events and death. A prospective cohort study
    • Levine SR, Salowich-Palm L, Sawaya KL, et al. IgG anticardiolipin antibody titer >40 GPL and the risk of subsequent thrombo-occlusive events and death. A prospective cohort study. Stroke 1997;28:1660.
    • (1997) Stroke , vol.28 , pp. 1660
    • Levine, S.R.1    Salowich-Palm, L.2    Sawaya, K.L.3
  • 45
    • 0029031918 scopus 로고
    • Recurrent stroke and thrombo-occlusive events in the antiphospholipid syndrome
    • Levine SR, Brey RL, Sawaya KL, et al. Recurrent stroke and thrombo-occlusive events in the antiphospholipid syndrome. Ann Neurol 1995;38:119.
    • (1995) Ann Neurol , vol.38 , pp. 119
    • Levine, S.R.1    Brey, R.L.2    Sawaya, K.L.3
  • 46
    • 0029617611 scopus 로고
    • Anticardiolipin antibodies in systemic lupus erythematosus: Clinical and laboratory correlations
    • Abu-Shakra M, Gladman DD, Urowitz MB, et al. Anticardiolipin antibodies in systemic lupus erythematosus: Clinical and laboratory correlations. Am J Med 1995;99:624.
    • (1995) Am J Med , vol.99 , pp. 624
    • Abu-Shakra, M.1    Gladman, D.D.2    Urowitz, M.B.3
  • 47
    • 0025102933 scopus 로고
    • Immunoglobulin G fractions from patients with antiphospholipid antibodies cause fetal death in Balb/c mice: A model for autoimmune fetal loss
    • Branch DW, Dudley DJ, Mitchell MD. Immunoglobulin G fractions from patients with antiphospholipid antibodies cause fetal death in Balb/c mice: A model for autoimmune fetal loss. Am J Obstet Gynecol 1990;163:210.
    • (1990) Am J Obstet Gynecol , vol.163 , pp. 210
    • Branch, D.W.1    Dudley, D.J.2    Mitchell, M.D.3
  • 48
    • 0028925978 scopus 로고
    • Placental thrombosis and fetal loss after passive transfer of mouse lupus monoclonal or human polyclonal anti-cardiolipin antibodies in pregnant naive BALB/c mice
    • Piona A, Larosa L, Tincani A, et al. Placental thrombosis and fetal loss after passive transfer of mouse lupus monoclonal or human polyclonal anti-cardiolipin antibodies in pregnant naive BALB/c mice. Scand J Immunol 1995;41:427.
    • (1995) Scand J Immunol , vol.41 , pp. 427
    • Piona, A.1    Larosa, L.2    Tincani, A.3
  • 49
    • 0026322836 scopus 로고
    • Induction of antiphospholipid syndrome in naive mice with mouse monoclonal and human polyclonal anticardiolipin antibodies
    • Blank M, Cohen J, Toder V, et al. Induction of antiphospholipid syndrome in naive mice with mouse monoclonal and human polyclonal anticardiolipin antibodies. Proc Natl Acad Sci USA 1991;88:3069.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 3069
    • Blank, M.1    Cohen, J.2    Toder, V.3
  • 50
    • 0028045047 scopus 로고
    • Induction of experimental antiphospholipid syndrome in naive mice with purified IgG antiphosphatidylserine antibodies
    • Blank M, Tincani A, Shoenfeld Y. Induction of experimental antiphospholipid syndrome in naive mice with purified IgG antiphosphatidylserine antibodies. J Rheumatol 1994;21:100.
    • (1994) J Rheumatol , vol.21 , pp. 100
    • Blank, M.1    Tincani, A.2    Shoenfeld, Y.3
  • 51
    • 0030069527 scopus 로고    scopus 로고
    • Effects of monoclonal anticardiolipin antibody in pregnant mice
    • Suzuki T, Takabayashi K, Ichikawa K, et al. Effects of monoclonal anticardiolipin antibody in pregnant mice. J Rheumatol 1996;23:83.
    • (1996) J Rheumatol , vol.23 , pp. 83
    • Suzuki, T.1    Takabayashi, K.2    Ichikawa, K.3
  • 52
    • 0028173807 scopus 로고
    • Effect of human IgG antiphospholipid antibodies on an in vivo thrombosis model in mice
    • Pierangeli SS, Barker JH, Stikovac D, et al. Effect of human IgG antiphospholipid antibodies on an in vivo thrombosis model in mice. Thromb Haemost 1994;71:670.
    • (1994) Thromb Haemost , vol.71 , pp. 670
    • Pierangeli, S.S.1    Barker, J.H.2    Stikovac, D.3
  • 53
    • 0028787634 scopus 로고
    • Induction of thrombosis in a mouse model by IgG, IgM and IgA immunoglobulins from patients with the antiphospholipid syndrome
    • Pierangeli SS, Liu X, Barker JH, et al. Induction of thrombosis in a mouse model by IgG, IgM and IgA immunoglobulins from patients with the antiphospholipid syndrome. Thromb Haemost 1995;74:1361.
    • (1995) Thromb Haemost , vol.74 , pp. 1361
    • Pierangeli, S.S.1    Liu, X.2    Barker, J.H.3
  • 54
    • 0026659095 scopus 로고
    • Antiphospholipid thrombosis: Clinical course after the first thrombotic event in 70 patients
    • Rosove MH, Brewer PM. Antiphospholipid thrombosis: Clinical course after the first thrombotic event in 70 patients. Ann Intern Med 1992;117:303.
    • (1992) Ann Intern Med , vol.117 , pp. 303
    • Rosove, M.H.1    Brewer, P.M.2
  • 55
    • 0018772977 scopus 로고
    • The binding of beta 2-glycoprotein-I to human serum lipoproteins: Distribution among density fractions
    • Polz E, Kostner GM. The binding of beta 2-glycoprotein-I to human serum lipoproteins: Distribution among density fractions. FEBS Lett 1979;102:183.
    • (1979) FEBS Lett , vol.102 , pp. 183
    • Polz, E.1    Kostner, G.M.2
  • 56
    • 0028972471 scopus 로고
    • Beta 2 glycoprotein I is a major protein associated with very rapidly cleared liposomes in vivo, suggesting a significant role in the immune clearance of "non-self" particles
    • Chonn A, Semple SC, Cullis PR. Beta 2 glycoprotein I is a major protein associated with very rapidly cleared liposomes in vivo, suggesting a significant role in the immune clearance of "non-self" particles. J Biol Chem 1995;270:25845.
    • (1995) J Biol Chem , vol.270 , pp. 25845
    • Chonn, A.1    Semple, S.C.2    Cullis, P.R.3
  • 57
    • 0031887591 scopus 로고    scopus 로고
    • Apoptotic cell clearance in systemic lupus erythematosus. II. Role of beta2-glycoprotein I
    • Manfredi AA, Rovere P, Heltai S, et al. Apoptotic cell clearance in systemic lupus erythematosus. II. Role of beta2-glycoprotein I. Arthritis Rheum 1998;41:215.
    • (1998) Arthritis Rheum , vol.41 , pp. 215
    • Manfredi, A.A.1    Rovere, P.2    Heltai, S.3
  • 58
    • 0032582647 scopus 로고    scopus 로고
    • Characterization of phosphatidylserine-dependent beta2-glycoprotein I macrophage interactions. Implications for apoptotic cell clearance by phagocytes
    • Balasubramanian K, Schroit AJ. Characterization of phosphatidylserine-dependent beta2-glycoprotein I macrophage interactions. Implications for apoptotic cell clearance by phagocytes. J Biol Chem 1998;273:29272.
    • (1998) J Biol Chem , vol.273 , pp. 29272
    • Balasubramanian, K.1    Schroit, A.J.2
  • 59
    • 0030007187 scopus 로고    scopus 로고
    • Beta 2-glycoprotein I in thrombosis: Evidence for a role as a natural anticoagulant
    • Brighton TA, Hogg PJ, Dai YP, et al. Beta 2-glycoprotein I in thrombosis: Evidence for a role as a natural anticoagulant. Br J Haematol 1996;93:185.
    • (1996) Br J Haematol , vol.93 , pp. 185
    • Brighton, T.A.1    Hogg, P.J.2    Dai, Y.P.3
  • 60
    • 0022490386 scopus 로고
    • Prothrombinase activity of human platelets is inhibited by beta2-glycoprotein-I
    • Nimpf J, Bevers EM, Bomans PH, et al. Prothrombinase activity of human platelets is inhibited by beta2-glycoprotein-I. Biochim Biophys Acta 1986;884:142.
    • (1986) Biochim Biophys Acta , vol.884 , pp. 142
    • Nimpf, J.1    Bevers, E.M.2    Bomans, P.H.3
  • 61
    • 0023132768 scopus 로고
    • Beta 2-glycoprotein-I (apo-H) inhibits the release reaction of human platelets during ADP-induced aggregation
    • Nimpf J, Wurm H, Kostner GM. Beta 2-glycoprotein-I (apo-H) inhibits the release reaction of human platelets during ADP-induced aggregation. Atherosclerosis 1987;63:109.
    • (1987) Atherosclerosis , vol.63 , pp. 109
    • Nimpf, J.1    Wurm, H.2    Kostner, G.M.3
  • 62
    • 45449125854 scopus 로고
    • Inhibition of the activation of Hageman factor (factor XII) by beta2-glycoprotein I
    • Henry ML, Everson B, Ratnoff OD. Inhibition of the activation of Hageman factor (factor XII) by beta2-glycoprotein I. J Lab Clin Med 1988;111:519.
    • (1988) J Lab Clin Med , vol.111 , pp. 519
    • Henry, M.L.1    Everson, B.2    Ratnoff, O.D.3
  • 63
    • 0022202304 scopus 로고
    • Beta 2-Glycoprotein I: A plasma inhibitor of the contact activation of the intrinsic blood coagulation pathway
    • Schousboe I. beta 2-Glycoprotein I: A plasma inhibitor of the contact activation of the intrinsic blood coagulation pathway. Blood 1985;66:1086.
    • (1985) Blood , vol.66 , pp. 1086
    • Schousboe, I.1
  • 64
    • 0032940243 scopus 로고    scopus 로고
    • Enhancement of protein S anticoagulant function by beta2-glycoprotein I, a major target antigen of antiphospholipid antibodies: Beta2-glycoprotein I interferes with binding of protein S to its plasma inhibitor, C4b-binding protein
    • Merrill JT, Zhang HW, Shen C, et al. Enhancement of protein S anticoagulant function by beta2-glycoprotein I, a major target antigen of antiphospholipid antibodies: beta2-glycoprotein I interferes with binding of protein S to its plasma inhibitor, C4b-binding protein. Thromb Haemost 1999;81:748.
    • (1999) Thromb Haemost , vol.81 , pp. 748
    • Merrill, J.T.1    Zhang, H.W.2    Shen, C.3
  • 65
    • 0031595910 scopus 로고    scopus 로고
    • The influence of beta2-glycoprotein I on tissue factor activity
    • Ieko M, Yasukouchi T, Sawada KI, et al. The influence of beta2-glycoprotein I on tissue factor activity. Semin Thromb Hemost 1998;24:211.
    • (1998) Semin Thromb Hemost , vol.24 , pp. 211
    • Ieko, M.1    Yasukouchi, T.2    Sawada, K.I.3
  • 67
    • 0034917281 scopus 로고    scopus 로고
    • Antiphospholipid syndrome: Diagnostic aspects of lupus anticoagulants
    • Arnout J. Antiphospholipid syndrome: Diagnostic aspects of lupus anticoagulants. Thromb Haemost 2001;86:83.
    • (2001) Thromb Haemost , vol.86 , pp. 83
    • Arnout, J.1
  • 68
    • 0034865785 scopus 로고    scopus 로고
    • Antiphospholipid antibodies and the coagulation cascade
    • Angles-Cano E, Guillin MC. Antiphospholipid antibodies and the coagulation cascade. Rheum Dis Clin North Am 2001;27:573.
    • (2001) Rheum Dis Clin North Am , vol.27 , pp. 573
    • Angles-Cano, E.1    Guillin, M.C.2
  • 69
    • 0030789659 scopus 로고    scopus 로고
    • Pregnancy loss in the antiphospholipid-antibody syndrome - A possible thrombogenic mechanism
    • Rand JH, Wu XX, Andree HA, et al. Pregnancy loss in the antiphospholipid-antibody syndrome - a possible thrombogenic mechanism. N Engl J Med 1997;337:154.
    • (1997) N Engl J Med , vol.337 , pp. 154
    • Rand, J.H.1    Wu, X.X.2    Andree, H.A.3
  • 70
    • 0032170963 scopus 로고    scopus 로고
    • Antiphospholipid antibodies accelerate plasma coagulation by inhibiting annexin-V binding to phospholipids: A "lupus procoagulant" phenomenon
    • Rand JH, Wu XX, Andree HA, et al. Antiphospholipid antibodies accelerate plasma coagulation by inhibiting annexin-V binding to phospholipids: A "lupus procoagulant" phenomenon. Blood 1998;92:1652.
    • (1998) Blood , vol.92 , pp. 1652
    • Rand, J.H.1    Wu, X.X.2    Andree, H.A.3
  • 71
    • 0033625340 scopus 로고    scopus 로고
    • Anti-beta2-glycoprotein I (GPI) autoantibodies, annexin V binding and the anti-phospholipid syndrome
    • Hanly JG, Smith SA. Anti-beta2-glycoprotein I (GPI) autoantibodies, annexin V binding and the anti-phospholipid syndrome. Clin Exp Immunol 2000;120:537.
    • (2000) Clin Exp Immunol , vol.120 , pp. 537
    • Hanly, J.G.1    Smith, S.A.2
  • 72
    • 0034060984 scopus 로고    scopus 로고
    • No evidence for enhanced thrombin formation through displacement of annexin V by antiphospholipid antibodies
    • Bevers EM, Janssen MP, Willems GM, et al. No evidence for enhanced thrombin formation through displacement of annexin V by antiphospholipid antibodies. Thromb Haemost 2000;83:792.
    • (2000) Thromb Haemost , vol.83 , pp. 792
    • Bevers, E.M.1    Janssen, M.P.2    Willems, G.M.3
  • 73
    • 0034728384 scopus 로고    scopus 로고
    • Competition of annexin V and anticardiolipin antibodies for binding to phosphatidylserine containing membranes
    • Willems GM, Janssen MP, Comfurius P, et al. Competition of annexin V and anticardiolipin antibodies for binding to phosphatidylserine containing membranes. Biochemistry 2000;39:1982.
    • (2000) Biochemistry , vol.39 , pp. 1982
    • Willems, G.M.1    Janssen, M.P.2    Comfurius, P.3
  • 74
    • 0033830963 scopus 로고    scopus 로고
    • The anticoagulant and anti-inflammatory roles of the protein C anticoagulant pathway
    • Esmon CT. The anticoagulant and anti-inflammatory roles of the protein C anticoagulant pathway. J Autoimmun 2000;15:113.
    • (2000) J Autoimmun , vol.15 , pp. 113
    • Esmon, C.T.1
  • 75
    • 0028827566 scopus 로고
    • The factor V Leiden mutation which predisposes to thrombosis is not common in patients with antiphospholipid syndrome
    • Dizon-Townson D, Hutchison C, Silver R, et al. The factor V Leiden mutation which predisposes to thrombosis is not common in patients with antiphospholipid syndrome. Thromb Haemost 1995;74:1029.
    • (1995) Thromb Haemost , vol.74 , pp. 1029
    • Dizon-Townson, D.1    Hutchison, C.2    Silver, R.3
  • 76
    • 0029859550 scopus 로고    scopus 로고
    • Free protein S deficiency may be found in patients with antiphospholipid antibodies who do not have systemic lupus erythematosus
    • Crowther MA, Johnston M, Weitz J, Ginsberg JS. Free protein S deficiency may be found in patients with antiphospholipid antibodies who do not have systemic lupus erythematosus. Thromb Haemost 1996;76:689.
    • (1996) Thromb Haemost , vol.76 , pp. 689
    • Crowther, M.A.1    Johnston, M.2    Weitz, J.3    Ginsberg, J.S.4
  • 77
    • 0029794426 scopus 로고    scopus 로고
    • Coagulation activation and fibrinolytic imbalance in subjects with idiopathic antiphospholipid antibodies - A crucial role for acquired free protein S deficiency
    • Ames PR, Tommasino C, Iannaccone L, et al. Coagulation activation and fibrinolytic imbalance in subjects with idiopathic antiphospholipid antibodies - a crucial role for acquired free protein S deficiency. Thromb Haemost 1996;76:190.
    • (1996) Thromb Haemost , vol.76 , pp. 190
    • Ames, P.R.1    Tommasino, C.2    Iannaccone, L.3
  • 78
    • 0026786517 scopus 로고
    • Immunoglobulin fractions isolated from patients with antiphospholipid antibodies prevent the inactivation of factor Va by activated protein C on human endothelial cells
    • Borrell M, Sala N, de Castellarnau C, et al. Immunoglobulin fractions isolated from patients with antiphospholipid antibodies prevent the inactivation of factor Va by activated protein C on human endothelial cells. Thromb Haemost 1992;68:268.
    • (1992) Thromb Haemost , vol.68 , pp. 268
    • Borrell, M.1    Sala, N.2    De Castellarnau, C.3
  • 79
    • 0025001363 scopus 로고
    • Inhibition of activated protein C and its cofactor protein S by antiphospholipid antibodies
    • Malia RG, Kitchen S, Greaves M, et al. Inhibition of activated protein C and its cofactor protein S by antiphospholipid antibodies. Br J Haematol 1990;76:101.
    • (1990) Br J Haematol , vol.76 , pp. 101
    • Malia, R.G.1    Kitchen, S.2    Greaves, M.3
  • 80
    • 0036036951 scopus 로고    scopus 로고
    • Acquired activated protein C resistance is associated with the co-existence of anti-prothrombin antibodies and lupus anticoagulant activity in patients with systemic lupus erythematosus
    • Nojima J, Kuratsune H, Suehisa E, et al. Acquired activated protein C resistance is associated with the co-existence of anti-prothrombin antibodies and lupus anticoagulant activity in patients with systemic lupus erythematosus. Br J Haematol 2002;118:577.
    • (2002) Br J Haematol , vol.118 , pp. 577
    • Nojima, J.1    Kuratsune, H.2    Suehisa, E.3
  • 81
    • 0025372355 scopus 로고
    • Lupus anticoagulant - Antiphospholipid antibodies and thrombophilia. Relation to protein C-protein S-thrombomodulin
    • Tsakiris DA, Settas L, Makris PE, et al. Lupus anticoagulant - antiphospholipid antibodies and thrombophilia. Relation to protein C - protein S - thrombomodulin. J Rheumatol 1990;17:785.
    • (1990) J Rheumatol , vol.17 , pp. 785
    • Tsakiris, D.A.1    Settas, L.2    Makris, P.E.3
  • 82
    • 0028261675 scopus 로고
    • A new variant of interaction between phospholipid antibodies and the protein C system
    • Bokarewa MI, Blomback M, Egberg N, et al. A new variant of interaction between phospholipid antibodies and the protein C system. Blood Coagul Fibrinolysis 1994;5:37.
    • (1994) Blood Coagul Fibrinolysis , vol.5 , pp. 37
    • Bokarewa, M.I.1    Blomback, M.2    Egberg, N.3
  • 83
    • 0023766962 scopus 로고
    • Effect of lupus anticoagulant on antithrombogenic properties of endothelial cells - Inhibition of thrombomodulin-dependent protein C activation
    • Cariou R, Tobelem G, Bellucci S, et al. Effect of lupus anticoagulant on antithrombogenic properties of endothelial cells - inhibition of thrombomodulin-dependent protein C activation. Thromb Haemost 1988;60:54.
    • (1988) Thromb Haemost , vol.60 , pp. 54
    • Cariou, R.1    Tobelem, G.2    Bellucci, S.3
  • 84
    • 0038015821 scopus 로고    scopus 로고
    • The concomitant presence of lupus anticoagulant, anticardiolipin and anti-beta2-glycoprotein antibodies could be associated with acquired activated protein C resistance in non-systemic lupus erythematosus patients
    • Gennari L, Blanco A, Alberto MF, et al. The concomitant presence of lupus anticoagulant, anticardiolipin and anti-beta2-glycoprotein antibodies could be associated with acquired activated protein C resistance in non-systemic lupus erythematosus patients. Br J Haematol 2003;121:527.
    • (2003) Br J Haematol , vol.121 , pp. 527
    • Gennari, L.1    Blanco, A.2    Alberto, M.F.3
  • 85
    • 0037975660 scopus 로고    scopus 로고
    • A thrombin-cross-reactive anticardiolipin antibody binds to and inhibits the anticoagulant function of activated protein C
    • Hwang KK, Yang CD, Yan W, et al. A thrombin-cross-reactive anticardiolipin antibody binds to and inhibits the anticoagulant function of activated protein C. Arthritis Rheum 2003;48:1622.
    • (2003) Arthritis Rheum , vol.48 , pp. 1622
    • Hwang, K.K.1    Yang, C.D.2    Yan, W.3
  • 86
    • 0029008870 scopus 로고
    • Inhibitory activity of anti-beta 2-glycoprotein I antibody on factor Va degradation by activated-protein C and its cofactor protein S
    • Matsuda J, Gohchi K, Kawasugi K, et al. Inhibitory activity of anti-beta 2-glycoprotein I antibody on factor Va degradation by activated-protein C and its cofactor protein S. Am J Hematol 1995;49:89.
    • (1995) Am J Hematol , vol.49 , pp. 89
    • Matsuda, J.1    Gohchi, K.2    Kawasugi, K.3
  • 87
    • 0031801589 scopus 로고    scopus 로고
    • Binding of anticardiolipin antibodies to protein C via beta2-glycoprotein I (beta2-GPI): A possible mechanism in the inhibitory effect of antiphospholipid antibodies on the protein C system
    • Atsumi T, Khamashta MA, Amengual O, et al. Binding of anticardiolipin antibodies to protein C via beta2-glycoprotein I (beta2-GPI): A possible mechanism in the inhibitory effect of antiphospholipid antibodies on the protein C system. Clin Exp Immunol 1998;112:325.
    • (1998) Clin Exp Immunol , vol.112 , pp. 325
    • Atsumi, T.1    Khamashta, M.A.2    Amengual, O.3
  • 88
    • 0027253088 scopus 로고
    • Antiphospholipid antibodies directed against a combination of phospholipids with prothrombin, protein C, or protein S: An explanation for their pathogenic mechanism?
    • Oosting JD, Derksen RH, Bobbink IW, et al. Antiphospholipid antibodies directed against a combination of phospholipids with prothrombin, protein C, or protein S: An explanation for their pathogenic mechanism? Blood 1993;81:2618.
    • (1993) Blood , vol.81 , pp. 2618
    • Oosting, J.D.1    Derksen, R.H.2    Bobbink, I.W.3
  • 89
    • 0033954611 scopus 로고    scopus 로고
    • Antibodies to thrombomodulin are found in patients with lupus anticoagulant and unexplained thrombosis
    • Carson CW, Comp PC, Rezaie AR, et al. Antibodies to thrombomodulin are found in patients with lupus anticoagulant and unexplained thrombosis. J Rheumatol 2000;27:384.
    • (2000) J Rheumatol , vol.27 , pp. 384
    • Carson, C.W.1    Comp, P.C.2    Rezaie, A.R.3
  • 90
    • 0029826217 scopus 로고    scopus 로고
    • Protein C and other cofactors involved in the binding of antiphospholipid antibodies: Relation to the pathogenesis of thrombosis
    • de Groot PG, Horbach DA, Derksen RH. Protein C and other cofactors involved in the binding of antiphospholipid antibodies: Relation to the pathogenesis of thrombosis. Lupus 1996;5:488.
    • (1996) Lupus , vol.5 , pp. 488
    • De Groot, P.G.1    Horbach, D.A.2    Derksen, R.H.3
  • 92
    • 0028804699 scopus 로고
    • On the role of phosphatidylethanolamine in the inhibition of activated protein C activity by antiphospholipid antibodies
    • Smirnov MD, Triplett DT, Comp PC, et al. On the role of phosphatidylethanolamine in the inhibition of activated protein C activity by antiphospholipid antibodies. J Clin Invest 1995;95:309.
    • (1995) J Clin Invest , vol.95 , pp. 309
    • Smirnov, M.D.1    Triplett, D.T.2    Comp, P.C.3
  • 93
    • 0033833603 scopus 로고    scopus 로고
    • Antiphospholipid antibodies and the protein C pathway
    • Esmon NL, Safa O, Smirnov MD, et al. Antiphospholipid antibodies and the protein C pathway. J Autoimmun 2000;15:221.
    • (2000) J Autoimmun , vol.15 , pp. 221
    • Esmon, N.L.1    Safa, O.2    Smirnov, M.D.3
  • 94
    • 0019960396 scopus 로고
    • "Lupus" anticoagulant and thrombosis - Possible role of inhibition of prostacyclin formation
    • Carreras LO, Vermylen JG. "Lupus" anticoagulant and thrombosis - possible role of inhibition of prostacyclin formation. Thromb Haemost 1982;48:38.
    • (1982) Thromb Haemost , vol.48 , pp. 38
    • Carreras, L.O.1    Vermylen, J.G.2
  • 95
    • 0025748059 scopus 로고
    • Imbalance of thromboxane/prostacyclin biosynthesis in patients with lupus anticoagulant
    • Lellouche F, Martinuzzo M, Said P, et al. Imbalance of thromboxane/prostacyclin biosynthesis in patients with lupus anticoagulant. Blood 1991;78:2894.
    • (1991) Blood , vol.78 , pp. 2894
    • Lellouche, F.1    Martinuzzo, M.2    Said, P.3
  • 96
    • 0028641308 scopus 로고
    • Lupus anticoagulant autoantibody induces apoptosis in umbilical vein endothelial cells: Involvement of annexin V
    • Nakamura N, Shidara Y, Kawaguchi N, et al. Lupus anticoagulant autoantibody induces apoptosis in umbilical vein endothelial cells: Involvement of annexin V. Biochem Biophys Res Commun 1994;205:1488.
    • (1994) Biochem Biophys Res Commun , vol.205 , pp. 1488
    • Nakamura, N.1    Shidara, Y.2    Kawaguchi, N.3
  • 97
    • 0032080664 scopus 로고    scopus 로고
    • Localization of the apoptosis -inducing activity of lupus anticoagulant in an annexin V-binding antibody subset
    • Nakamura N, Ban T, Yamaji K, et al. Localization of the apoptosis -inducing activity of lupus anticoagulant in an annexin V-binding antibody subset. J Clin Invest 1998;101:1951.
    • (1998) J Clin Invest , vol.101 , pp. 1951
    • Nakamura, N.1    Ban, T.2    Yamaji, K.3
  • 98
    • 0030956584 scopus 로고    scopus 로고
    • Apoptotic vascular endothelial cells become procoagulant
    • Bombeli T, Karsan A, Tait JF, et al. Apoptotic vascular endothelial cells become procoagulant. Blood 1997;89:2429.
    • (1997) Blood , vol.89 , pp. 2429
    • Bombeli, T.1    Karsan, A.2    Tait, J.F.3
  • 99
    • 0037090094 scopus 로고    scopus 로고
    • Antiphospholipid anti-bodies induce monocyte chemoattractant protein-1 in endothelial cells
    • Cho CS, Cho ML, Chen PP, et al. Antiphospholipid anti-bodies induce monocyte chemoattractant protein-1 in endothelial cells. J Immunol 2002;168:4209.
    • (2002) J Immunol , vol.168 , pp. 4209
    • Cho, C.S.1    Cho, M.L.2    Chen, P.P.3
  • 100
    • 0030897237 scopus 로고    scopus 로고
    • Endothelial cells as target for antiphospholipid antibodies. Human polyclonal and monoclonal anti-beta 2-glycoprotein I anti-bodies react in vitro with endothelial cells through adherent beta 2-glycoprotein I and induce endothelial activation
    • Del Papa N, Guidali L, Sala A, et al. Endothelial cells as target for antiphospholipid antibodies. Human polyclonal and monoclonal anti-beta 2-glycoprotein I anti-bodies react in vitro with endothelial cells through adherent beta 2-glycoprotein I and induce endothelial activation. Arthritis Rheum 1997;40:551.
    • (1997) Arthritis Rheum , vol.40 , pp. 551
    • Del Papa, N.1    Guidali, L.2    Sala, A.3
  • 101
    • 0028941808 scopus 로고
    • Relationship between anti-phospholipid and anti-endothelial cell anti-bodies III: Beta 2 glycoprotein I mediates the antibody binding to endothelial membranes and induces the expression of adhesion molecules
    • Del Papa N, Guidali L, Spatola L, et al. Relationship between anti-phospholipid and anti-endothelial cell anti-bodies III: beta 2 glycoprotein I mediates the antibody binding to endothelial membranes and induces the expression of adhesion molecules. Clin Exp Rheumatol 1995;13:179.
    • (1995) Clin Exp Rheumatol , vol.13 , pp. 179
    • Del Papa, N.1    Guidali, L.2    Spatola, L.3
  • 102
    • 0028883356 scopus 로고
    • Activation of cultured vascular endothelial cells by antiphospholipid antibodies
    • Simantov R, LaSala JM, Lo SK, et al. Activation of cultured vascular endothelial cells by antiphospholipid antibodies. J Clin Invest 1995;96:2211.
    • (1995) J Clin Invest , vol.96 , pp. 2211
    • Simantov, R.1    LaSala, J.M.2    Lo, S.K.3
  • 103
    • 0032502289 scopus 로고    scopus 로고
    • Differential effects of anti-beta2-glycoprotein I antibodies on endothelial cells and on the manifestations of experimental antiphospholipid syndrome
    • George J, Blank M, Levy Y, et al. Differential effects of anti-beta2-glycoprotein I antibodies on endothelial cells and on the manifestations of experimental antiphospholipid syndrome. Circulation 1998;97:900.
    • (1998) Circulation , vol.97 , pp. 900
    • George, J.1    Blank, M.2    Levy, Y.3
  • 104
    • 0033586656 scopus 로고    scopus 로고
    • Antiphospholipid antibodies from antiphospholipid syndrome patients activate endothelial cells in vitro and in vivo
    • Pierangeli SS, Colden-Stanfield M, Liu X, et al. Antiphospholipid antibodies from antiphospholipid syndrome patients activate endothelial cells in vitro and in vivo. Circulation 1999;99:1997.
    • (1999) Circulation , vol.99 , pp. 1997
    • Pierangeli, S.S.1    Colden-Stanfield, M.2    Liu, X.3
  • 105
    • 0034085616 scopus 로고    scopus 로고
    • Increased soluble vascular cell adhesion molecule 1 concentrations in patients with primary or systemic lupus erythematosus-related antiphospholipid syndrome: Correlations with the severity of thrombosis
    • Kaplanski G, Cacoub P, Farnarier C, et al. Increased soluble vascular cell adhesion molecule 1 concentrations in patients with primary or systemic lupus erythematosus-related antiphospholipid syndrome: Correlations with the severity of thrombosis. Arthritis Rheum 2000;43:55.
    • (2000) Arthritis Rheum , vol.43 , pp. 55
    • Kaplanski, G.1    Cacoub, P.2    Farnarier, C.3
  • 106
    • 0033834768 scopus 로고    scopus 로고
    • Experimental thrombosis and antiphospholipid antibodies: New insights
    • Pierangeli SS, Gharavi AE, Harris EN. Experimental thrombosis and antiphospholipid antibodies: New insights. J Autoimmun 2000;15:241.
    • (2000) J Autoimmun , vol.15 , pp. 241
    • Pierangeli, S.S.1    Gharavi, A.E.2    Harris, E.N.3
  • 107
    • 0030857363 scopus 로고    scopus 로고
    • Tissue factor in health and disease
    • Semeraro N, Colucci M. Tissue factor in health and disease. Thromb Haemost 1997;78:759.
    • (1997) Thromb Haemost , vol.78 , pp. 759
    • Semeraro, N.1    Colucci, M.2
  • 108
    • 0031886679 scopus 로고    scopus 로고
    • The role of the tissue factor pathway in the hypercoagulable state in patients with the antiphospholipid syndrome
    • Amengual O, Atsumi T, Khamashta MA, et al. The role of the tissue factor pathway in the hypercoagulable state in patients with the antiphospholipid syndrome. Thromb Haemost 1998;79:276.
    • (1998) Thromb Haemost , vol.79 , pp. 276
    • Amengual, O.1    Atsumi, T.2    Khamashta, M.A.3
  • 109
    • 1842413134 scopus 로고    scopus 로고
    • Thrombosis in primary antiphospholipid syndrome: A pivotal role for monocyte tissue factor expression
    • Cuadrado MJ, Lopez-Pedrera C, Khamashta MA, et al. Thrombosis in primary antiphospholipid syndrome: A pivotal role for monocyte tissue factor expression. Arthritis Rheum 1997;40:834.
    • (1997) Arthritis Rheum , vol.40 , pp. 834
    • Cuadrado, M.J.1    Lopez-Pedrera, C.2    Khamashta, M.A.3
  • 110
    • 0032700453 scopus 로고    scopus 로고
    • Increased levels of tissue factor mRNA in mononuclear blood cells of patients with primary antiphospholipid syndrome
    • Dobado-Berrios PM, Lopez-Pedrera C, Velasco F, et al. Increased levels of tissue factor mRNA in mononuclear blood cells of patients with primary antiphospholipid syndrome. Thromb Haemost 1999;82:1578.
    • (1999) Thromb Haemost , vol.82 , pp. 1578
    • Dobado-Berrios, P.M.1    Lopez-Pedrera, C.2    Velasco, F.3
  • 111
    • 0033623763 scopus 로고    scopus 로고
    • Anti-beta 2-glycoprotein I antibodies and anti-endothelial cell anti-bodies induce tissue factor in endothelial cells
    • Kornberg A, Renaudineau Y, Blank M, et al. Anti-beta 2-glycoprotein I antibodies and anti-endothelial cell anti-bodies induce tissue factor in endothelial cells. Isr Med Assoc J 2000;2 Suppl:27.
    • (2000) Isr Med Assoc J , vol.2 , Issue.SUPPL. , pp. 27
    • Kornberg, A.1    Renaudineau, Y.2    Blank, M.3
  • 112
    • 0027474773 scopus 로고
    • Induction of endothelial cell tissue factor activity by sera from patients with antiphospholipid syndrome: A possible mechanism of thrombosis
    • Branch DW, Rodgers GM. Induction of endothelial cell tissue factor activity by sera from patients with antiphospholipid syndrome: A possible mechanism of thrombosis. Am J Obstet Gynecol 1993;168:206.
    • (1993) Am J Obstet Gynecol , vol.168 , pp. 206
    • Branch, D.W.1    Rodgers, G.M.2
  • 113
    • 0028365677 scopus 로고
    • Induction of tissue factor-like activity in monocytes by anti-cardiolipin antibodies
    • Kornberg A, Blank M, Kaufman S, et al. Induction of tissue factor-like activity in monocytes by anti-cardiolipin antibodies. J Immunol 1994;153:1328.
    • (1994) J Immunol , vol.153 , pp. 1328
    • Kornberg, A.1    Blank, M.2    Kaufman, S.3
  • 114
    • 0033626575 scopus 로고    scopus 로고
    • Antibodies to beta2-glycoprotein I associated with antiphospholipid syndrome suppress the inhibitory activity of tissue factor pathway inhibitor
    • Salemink I, Blezer R, Willems GM, et al. Antibodies to beta2-glycoprotein I associated with antiphospholipid syndrome suppress the inhibitory activity of tissue factor pathway inhibitor. Thromb Haemost 2000;84:653.
    • (2000) Thromb Haemost , vol.84 , pp. 653
    • Salemink, I.1    Blezer, R.2    Willems, G.M.3
  • 115
    • 0034883353 scopus 로고    scopus 로고
    • Anti-tissue factor pathway inhibitor activity in patients with primary antiphospholipid syndrome
    • Adams MJ, Donohoe S, Mackie IJ, et al. Anti-tissue factor pathway inhibitor activity in patients with primary antiphospholipid syndrome. Br J Haematol 2001;114:375.
    • (2001) Br J Haematol , vol.114 , pp. 375
    • Adams, M.J.1    Donohoe, S.2    Mackie, I.J.3
  • 116
    • 0017267777 scopus 로고
    • Immunochemical properties of glycolipids and phospholipids
    • Marcus DM, Schwarting GA. Immunochemical properties of glycolipids and phospholipids. Adv Immunol 1976;23:203.
    • (1976) Adv Immunol , vol.23 , pp. 203
    • Marcus, D.M.1    Schwarting, G.A.2
  • 117
    • 0026726649 scopus 로고
    • Induction of antiphospholipid autoantibodies by immunization with beta 2 glycoprotein I (apolipoprotein H)
    • Gharavi AE, Sammaritano LR, Wen J, et al. Induction of antiphospholipid autoantibodies by immunization with beta 2 glycoprotein I (apolipoprotein H). J Clin Invest 1992;90:1105.
    • (1992) J Clin Invest , vol.90 , pp. 1105
    • Gharavi, A.E.1    Sammaritano, L.R.2    Wen, J.3
  • 118
    • 0028980074 scopus 로고
    • Specificities and characteristics of beta 2 glycoprotein I-induced antiphospholipid antibodies
    • Gharavi AE, Sammaritano LR, Bovastro JL Jr, et al. Specificities and characteristics of beta 2 glycoprotein I-induced antiphospholipid antibodies. J Lab Clin Med 1995;125:775.
    • (1995) J Lab Clin Med , vol.125 , pp. 775
    • Gharavi, A.E.1    Sammaritano, L.R.2    Bovastro Jr., J.L.3
  • 119
    • 0028169961 scopus 로고
    • Immunization with anticardiolipin cofactor (beta-2-glycoprotein I) induces experimental antiphospholipid syndrome in naive mice
    • Blank M, Faden D, Tincani A, et al. Immunization with anticardiolipin cofactor (beta-2-glycoprotein I) induces experimental antiphospholipid syndrome in naive mice. J Autoimmun 1994;7:441.
    • (1994) J Autoimmun , vol.7 , pp. 441
    • Blank, M.1    Faden, D.2    Tincani, A.3
  • 120
    • 0031053572 scopus 로고    scopus 로고
    • Induction of experimental antiphospholipid syndrome in PL/J mice following immunization with beta2 GPI
    • Garcia CO, Kanbour-Shakir A, Tang H, et al. Induction of experimental antiphospholipid syndrome in PL/J mice following immunization with beta2 GPI. Am J Reprod Immunol 1997;37:118.
    • (1997) Am J Reprod Immunol , vol.37 , pp. 118
    • Garcia, C.O.1    Kanbour-Shakir, A.2    Tang, H.3
  • 121
    • 0033197971 scopus 로고    scopus 로고
    • GDKV-induced antiphospholipid antibodies enhance thrombosis and activate endothelial cells in vivo and in vitro
    • Gharavi AE, Pierangeli SS, Colden-Stanfield M, et al. GDKV-induced antiphospholipid antibodies enhance thrombosis and activate endothelial cells in vivo and in vitro. J Immunol 1999;163:2922.
    • (1999) J Immunol , vol.163 , pp. 2922
    • Gharavi, A.E.1    Pierangeli, S.S.2    Colden-Stanfield, M.3
  • 122
    • 0032847566 scopus 로고    scopus 로고
    • Induction of antiphospholipid antibodies by immunization with synthetic viral and bacterial peptides
    • Gharavi EE, Chaimovich H, Cucurull E, et al. Induction of antiphospholipid antibodies by immunization with synthetic viral and bacterial peptides. Lupus 1999;8:449.
    • (1999) Lupus , vol.8 , pp. 449
    • Gharavi, E.E.1    Chaimovich, H.2    Cucurull, E.3
  • 123
    • 0036169798 scopus 로고    scopus 로고
    • Anti-phospholipid antibodies induced in mice by immunization with a cytomegalovirus-derived peptide cause thrombosis and activation of endothelial cells in vivo
    • Gharavi AE, Pierangeli SS, Espinola RG, et al. Anti-phospholipid antibodies induced in mice by immunization with a cytomegalovirus-derived peptide cause thrombosis and activation of endothelial cells in vivo. Arthritis Rheum 2002;46:545.
    • (2002) Arthritis Rheum , vol.46 , pp. 545
    • Gharavi, A.E.1    Pierangeli, S.S.2    Espinola, R.G.3
  • 125
    • 0141517177 scopus 로고    scopus 로고
    • Current status and implications of autoimmune antiphospholipid antibodies in relation to thrombotic disease
    • Arnout J, Vermylen J. Current status and implications of autoimmune antiphospholipid antibodies in relation to thrombotic disease. J Thromb Haemost 2003;1:931.
    • (2003) J Thromb Haemost , vol.1 , pp. 931
    • Arnout, J.1    Vermylen, J.2
  • 126
    • 0021047734 scopus 로고
    • Changes in membrane phospholipid distribution during platelet activation
    • Bevers EM, Comfurius P, Zwaal RF. Changes in membrane phospholipid distribution during platelet activation. Biochim Biophys Acta 1983;736:57.
    • (1983) Biochim Biophys Acta , vol.736 , pp. 57
    • Bevers, E.M.1    Comfurius, P.2    Zwaal, R.F.3
  • 127
    • 0030240765 scopus 로고    scopus 로고
    • Anti-phospholipid autoantibodies bind to apoptotic, but not viable, thymocytes in a beta 2-glycoprotein I-dependent manner
    • Price BE, Rauch J, Shia MA, et al. Anti-phospholipid autoantibodies bind to apoptotic, but not viable, thymocytes in a beta 2-glycoprotein I-dependent manner. J Immunol 1996;157:2201.
    • (1996) J Immunol , vol.157 , pp. 2201
    • Price, B.E.1    Rauch, J.2    Shia, M.A.3
  • 128
    • 0033732503 scopus 로고    scopus 로고
    • Cardiolipin on the surface of apoptotic cells as a possible trigger for antiphospholipids antibodies
    • Sorice M, Circella A, Misasi R, et al. Cardiolipin on the surface of apoptotic cells as a possible trigger for antiphospholipids antibodies. Clin Exp Immunol 2000;122:277.
    • (2000) Clin Exp Immunol , vol.122 , pp. 277
    • Sorice, M.1    Circella, A.2    Misasi, R.3
  • 129
    • 0031934896 scopus 로고    scopus 로고
    • Apoptotic cell clearance in systemic lupus erythematosus. I. Opsonization by antiphospholipid antibodies
    • Manfredi AA, Rovere P, Galati G, et al. Apoptotic cell clearance in systemic lupus erythematosus. I. Opsonization by antiphospholipid antibodies. Arthritis Rheum 1998;41:205.
    • (1998) Arthritis Rheum , vol.41 , pp. 205
    • Manfredi, A.A.1    Rovere, P.2    Galati, G.3
  • 130
    • 0032191322 scopus 로고    scopus 로고
    • Induction of antiphospholipid autoantibodies by beta2-glycoprotein I bound to apoptotic thymocytes
    • Levine JS, Subang R, Koh JS, et al. Induction of antiphospholipid autoantibodies by beta2-glycoprotein I bound to apoptotic thymocytes. J Autoimmun 1998;11:413.
    • (1998) J Autoimmun , vol.11 , pp. 413
    • Levine, J.S.1    Subang, R.2    Koh, J.S.3
  • 131
    • 0034458554 scopus 로고    scopus 로고
    • Phospholipid-bound beta 2-glycoprotein I induces the production of anti-phospholipid antibodies
    • Subang R, Levine JS, Janoff AS, et al. Phospholipid-bound beta 2-glycoprotein I induces the production of anti-phospholipid antibodies. J Autoimmun 2000;15:21,
    • (2000) J Autoimmun , vol.15 , pp. 21
    • Subang, R.1    Levine, J.S.2    Janoff, A.S.3
  • 132
    • 0034066625 scopus 로고    scopus 로고
    • Human monoclonal anti-phospholipid antibodies selectively bind to membrane phospholipid and beta2-glycoprotein I (beta2-GPI) on apoptotic cells
    • Pittoni V, Ravirajan CT, Donohoe S, et al. Human monoclonal anti-phospholipid antibodies selectively bind to membrane phospholipid and beta2-glycoprotein I (beta2-GPI) on apoptotic cells. Clin Exp Immunol 2000;119:533.
    • (2000) Clin Exp Immunol , vol.119 , pp. 533
    • Pittoni, V.1    Ravirajan, C.T.2    Donohoe, S.3
  • 133
    • 0033830514 scopus 로고    scopus 로고
    • Apoptosis and the antiphospholipid syndrome
    • Rauch J, Subang R, D'Agnillo P, et al. Apoptosis and the antiphospholipid syndrome. J Autoimmun 2000;15:231.
    • (2000) J Autoimmun , vol.15 , pp. 231
    • Rauch, J.1    Subang, R.2    D'Agnillo, P.3
  • 134
    • 0038871839 scopus 로고    scopus 로고
    • Antiphospholipid anti-bodies are directed against epitopes of oxidized phospholipids. Recognition of cardiolipin by monoclonal antibodies to epitopes of oxidized low density lipoprotein
    • Horkko S, Miller E, Dudl E, et al. Antiphospholipid anti-bodies are directed against epitopes of oxidized phospholipids. Recognition of cardiolipin by monoclonal antibodies to epitopes of oxidized low density lipoprotein. J Clin Invest 1996;98:815.
    • (1996) J Clin Invest , vol.98 , pp. 815
    • Horkko, S.1    Miller, E.2    Dudl, E.3
  • 135
    • 0030931521 scopus 로고    scopus 로고
    • The epitopes for some antiphospholipid antibodies are adducts of oxidized phospholipid and beta2 glycoprotein 1 (and other proteins)
    • Horkko S, Miller E, Branch DW, et al. The epitopes for some antiphospholipid antibodies are adducts of oxidized phospholipid and beta2 glycoprotein 1 (and other proteins). Proc Natl Acad Sci USA 1997;94:10356.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 10356
    • Horkko, S.1    Miller, E.2    Branch, D.W.3
  • 136
    • 0030999857 scopus 로고    scopus 로고
    • Bcl-2 inhibits selective oxidation and externalization of phosphatidylserine during paraquat-induced apoptosis
    • Fabisiak JP, Kagan VE, Ritov VB, et al. Bcl-2 inhibits selective oxidation and externalization of phosphatidylserine during paraquat-induced apoptosis. Am J Physiol 1997;272 (2 Pt 1):C675.
    • (1997) Am J Physiol , vol.272 , Issue.2 PART 1
    • Fabisiak, J.P.1    Kagan, V.E.2    Ritov, V.B.3
  • 137
    • 0027485461 scopus 로고
    • Bcl-2 functions in an antioxidant pathway to prevent apoptosis
    • Hockenbery DM, Oltvai ZN, Yin XM, et al. Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 1993;75:241.
    • (1993) Cell , vol.75 , pp. 241
    • Hockenbery, D.M.1    Oltvai, Z.N.2    Yin, X.M.3
  • 138
    • 0028216441 scopus 로고
    • Exposure of anionic phospholipids upon platelet activation permits binding of beta 2 glycoprotein I and through it that of IgG antiphospholipid antibodies. Studies in platelets from patients with antiphospholipid syndrome and normal subjects
    • Vazquez-Mellado J, Llorente L, Richaud-Patin Y, et al. Exposure of anionic phospholipids upon platelet activation permits binding of beta 2 glycoprotein I and through it that of IgG antiphospholipid antibodies. Studies in platelets from patients with antiphospholipid syndrome and normal subjects. J Autoimmun 1994;7:335.
    • (1994) J Autoimmun , vol.7 , pp. 335
    • Vazquez-Mellado, J.1    Llorente, L.2    Richaud-Patin, Y.3
  • 139
    • 0027408150 scopus 로고
    • β2-glycoprotein-I is a requirement for anticardiolipin antibodies binding to activated platelets: Differences with lupus anticoagulants
    • Shi W, Chong BH, Chesterman CN. β2-Glycoprotein-I is a requirement for anticardiolipin antibodies binding to activated platelets: Differences with lupus anticoagulants. Blood 1993;81:1255.
    • (1993) Blood , vol.81 , pp. 1255
    • Shi, W.1    Chong, B.H.2    Chesterman, C.N.3
  • 140
    • 0027375161 scopus 로고
    • Antiphospholipid antibodies enhance thrombin-induced platelet activation and thromboxane formation
    • Martinuzzo ME, Maclouf J, Carreras LO, et al. Antiphospholipid antibodies enhance thrombin-induced platelet activation and thromboxane formation. Thromb Haemost 1993;70:667.
    • (1993) Thromb Haemost , vol.70 , pp. 667
    • Martinuzzo, M.E.1    Maclouf, J.2    Carreras, L.O.3
  • 141
    • 0028836875 scopus 로고
    • Effect of plasma from patients with primary antiphospholipid syndrome on platelet function in a collagen rich perfusion system
    • Reverter JC, Tassies D, Escolar G, et al. Effect of plasma from patients with primary antiphospholipid syndrome on platelet function in a collagen rich perfusion system. Thromb Haemost 1995;73:132.
    • (1995) Thromb Haemost , vol.73 , pp. 132
    • Reverter, J.C.1    Tassies, D.2    Escolar, G.3
  • 142
    • 0028959014 scopus 로고
    • Comparison of the effects of anticardiolipin antibodies from patients with the antiphospholipid syndrome and with syphilis on platelet activation and aggregation
    • Campbell AL, Pierangeli SS, Wellhausen S, et al. Comparison of the effects of anticardiolipin antibodies from patients with the antiphospholipid syndrome and with syphilis on platelet activation and aggregation. Thromb Haemost 1995;73:529.
    • (1995) Thromb Haemost , vol.73 , pp. 529
    • Campbell, A.L.1    Pierangeli, S.S.2    Wellhausen, S.3
  • 143
    • 0027208613 scopus 로고
    • Platelet activating properties of murine monoclonal antibodies to beta 2-glycoprotein I
    • Arvieux J, Roussel B, Pouzol P, et al. Platelet activating properties of murine monoclonal antibodies to beta 2-glycoprotein I. Thromb Haemost 1993;70:336.
    • (1993) Thromb Haemost , vol.70 , pp. 336
    • Arvieux, J.1    Roussel, B.2    Pouzol, P.3
  • 144
    • 0032977190 scopus 로고    scopus 로고
    • Platelet activation induced by combined effects of anticardiolipin and lupus anticoagulant IgG antibodies in patients with systemic lupus erythematosus - Possible association with thrombotic and thrombocytopenic complications
    • Nojima J, Suehisa E, Kuratsune H, et al. Platelet activation induced by combined effects of anticardiolipin and lupus anticoagulant IgG antibodies in patients with systemic lupus erythematosus - possible association with thrombotic and thrombocytopenic complications. Thromb Haemost 1999;81:436.
    • (1999) Thromb Haemost , vol.81 , pp. 436
    • Nojima, J.1    Suehisa, E.2    Kuratsune, H.3
  • 145
    • 0035424065 scopus 로고    scopus 로고
    • Thromboagglutination by anticardiolipin antibody complex in the antiphospholipid syndrome: A possible mechanism of immune-mediated thrombosis
    • Wiener MH, Burke M, Fried M, et al. Thromboagglutination by anticardiolipin antibody complex in the antiphospholipid syndrome: A possible mechanism of immune-mediated thrombosis. Thromb Res 2001;103:193.
    • (2001) Thromb Res , vol.103 , pp. 193
    • Wiener, M.H.1    Burke, M.2    Fried, M.3
  • 146
    • 0030866279 scopus 로고    scopus 로고
    • Possible pathogenetic role of activated platelets in the primary antiphospholipid syndrome involving the central nervous system
    • Emmi L, Bergamini C, Spinelli A, et al. Possible pathogenetic role of activated platelets in the primary antiphospholipid syndrome involving the central nervous system. Ann NY Acad Sci 1997;823:188.
    • (1997) Ann NY Acad Sci , vol.823 , pp. 188
    • Emmi, L.1    Bergamini, C.2    Spinelli, A.3
  • 147
    • 0031838124 scopus 로고    scopus 로고
    • IgG from patients with antiphospholipid syndrome binds to platelets without induction of platelet activation
    • Ford I, Urbaniak S, Greaves M. IgG from patients with antiphospholipid syndrome binds to platelets without induction of platelet activation. Br J Haematol 1998;102:841.
    • (1998) Br J Haematol , vol.102 , pp. 841
    • Ford, I.1    Urbaniak, S.2    Greaves, M.3
  • 148
    • 0033577484 scopus 로고    scopus 로고
    • Antiphospholipid antibodies and thrombosis
    • Greaves M. Antiphospholipid antibodies and thrombosis. Lancet 1999;353:1348.
    • (1999) Lancet , vol.353 , pp. 1348
    • Greaves, M.1
  • 149
    • 0030861626 scopus 로고    scopus 로고
    • Specific anti-platelet glycoprotein autoantibodies are associated with the thrombocytopenia of primary antiphospholipid syndrome
    • Godeau B, Piette JC, Fromont P, et al. Specific anti-platelet glycoprotein autoantibodies are associated with the thrombocytopenia of primary antiphospholipid syndrome. Br J Haematol 1997;98:873.
    • (1997) Br J Haematol , vol.98 , pp. 873
    • Godeau, B.1    Piette, J.C.2    Fromont, P.3
  • 150
    • 0030763968 scopus 로고    scopus 로고
    • Anti-platelet antibodies in patients with systemic lupus erythematosus and the primary antiphospholipid-antibody syndrome: Their relationship with the observed thrombocytopenia
    • Macchi L, Rispal P, Clofent-Sanchez G, et al. Anti-platelet antibodies in patients with systemic lupus erythematosus and the primary antiphospholipid-antibody. syndrome: Their relationship with the observed thrombocytopenia. Br J Haematol 1997;98:336.
    • (1997) Br J Haematol , vol.98 , pp. 336
    • Macchi, L.1    Rispal, P.2    Clofent-Sanchez, G.3
  • 151
    • 0029918326 scopus 로고    scopus 로고
    • The pathogenesis of the antiphospholipid syndrome: A hypothesis based on parellelism with heparin-induced thrombocytopenia
    • Arnout J. The pathogenesis of the antiphospholipid syndrome: A hypothesis based on parellelism with heparin-induced thrombocytopenia. Thromb Haemost 1996; 75:536.
    • (1996) Thromb Haemost , vol.75 , pp. 536
    • Arnout, J.1
  • 152
    • 0032753799 scopus 로고    scopus 로고
    • Vascular damage correlates between heparin-induced thrombocytopenia and the antiphospholipid syndrome
    • Walenga JM, Michal K, Hoppensteadt D, et al. Vascular damage correlates between heparin-induced thrombocytopenia and the antiphospholipid syndrome. Clin Appl Thromb Hemost 1999;5 Suppl 1:S76.
    • (1999) Clin Appl Thromb Hemost , vol.5 , Issue.SUPPL. 1
    • Walenga, J.M.1    Michal, K.2    Hoppensteadt, D.3
  • 153
    • 0037217897 scopus 로고    scopus 로고
    • Thrombogenicity of beta-2-glycoprotein I dependent antiphospholipid antibodies in a photochemically induced thrombosis in the hamster
    • Jankowski M, Vreys I, Wittevrongel C, et al. Thrombogenicity of beta-2-glycoprotein I dependent antiphospholipid antibodies in a photochemically induced thrombosis in the hamster. Blood 2003;101:157.
    • (2003) Blood , vol.101 , pp. 157
    • Jankowski, M.1    Vreys, I.2    Wittevrongel, C.3
  • 154
    • 0028282987 scopus 로고
    • The immunobiology and obstetrical consequences of antiphospholipid antibodies
    • Lockwood CJ, Rand JH. The immunobiology and obstetrical consequences of antiphospholipid antibodies. Obstet Gynecol Surv 1994;49:432.
    • (1994) Obstet Gynecol Surv , vol.49 , pp. 432
    • Lockwood, C.J.1    Rand, J.H.2
  • 155
    • 0025823651 scopus 로고
    • Histopathological findings in placentae from patients with intra-uterine fetal death and anti-phospholipid antibodies
    • Out HJ, Kooijman CD, Bruinse HW, et al. Histopathological findings in placentae from patients with intra-uterine fetal death and anti-phospholipid antibodies. Eur J Obstet Gynecol Reprod Biol 1991;41:179.
    • (1991) Eur J Obstet Gynecol Reprod Biol , vol.41 , pp. 179
    • Out, H.J.1    Kooijman, C.D.2    Bruinse, H.W.3
  • 156
    • 0027933860 scopus 로고
    • The expression of the placental anticoagulant protein, annexin V, by villous trophoblasts: Immunolocalization and in vitro regulation
    • Krikun G, Lockwood CJ, Wu XX, et al. The expression of the placental anticoagulant protein, annexin V, by villous trophoblasts: Immunolocalization and in vitro regulation. Placenta 1994;15:601.
    • (1994) Placenta , vol.15 , pp. 601
    • Krikun, G.1    Lockwood, C.J.2    Wu, X.X.3
  • 157
    • 0001110232 scopus 로고    scopus 로고
    • Annexin V is critical in the maintenance of murine placental integrity
    • Wang X, Campos B, Kaetzel MA, et al. Annexin V is critical in the maintenance of murine placental integrity. Am J Obstet Gynecol 1999;180:1008.
    • (1999) Am J Obstet Gynecol , vol.180 , pp. 1008
    • Wang, X.1    Campos, B.2    Kaetzel, M.A.3
  • 158
    • 0028586742 scopus 로고
    • Reduction of annexin-V (placental anticoagulant protein-I) on placental villi of women with antiphospholipid antibodies and recurrent spontaneous abortion
    • Rand JH, Wu XX, Guller S, et al. Reduction of annexin-V (placental anticoagulant protein-I) on placental villi of women with antiphospholipid antibodies and recurrent spontaneous abortion. Am J Obstet Gynecol 1994;171:1566.
    • (1994) Am J Obstet Gynecol , vol.171 , pp. 1566
    • Rand, J.H.1    Wu, X.X.2    Guller, S.3
  • 159
    • 0031975690 scopus 로고    scopus 로고
    • The role of placental trophoblast in the pathophysiology of the antiphospholipid antibody syndrome
    • Rote NS, Vogt E, DeVere G, et al. The role of placental trophoblast in the pathophysiology of the antiphospholipid antibody syndrome. Am J Reprod Immunol 1998;39:125.
    • (1998) Am J Reprod Immunol , vol.39 , pp. 125
    • Rote, N.S.1    Vogt, E.2    DeVere, G.3
  • 160
    • 0032838106 scopus 로고    scopus 로고
    • Normal expression of tissue factor, thrombomodulin, and annexin V in placentas from women with antiphospholipid syndrome
    • Lakasing L, Campa JS, Poston R, et al. Normal expression of tissue factor, thrombomodulin, and annexin V in placentas from women with antiphospholipid syndrome. Am J Obstet Gynecol 1999;181:180.
    • (1999) Am J Obstet Gynecol , vol.181 , pp. 180
    • Lakasing, L.1    Campa, J.S.2    Poston, R.3
  • 161
    • 0036659775 scopus 로고    scopus 로고
    • Up-date on the antiphospholipid syndrome
    • Luzzana C, Gerosa M, Riboldi P, et al. Up-date on the antiphospholipid syndrome. J Nephrol 2002;15:342.
    • (2002) J Nephrol , vol.15 , pp. 342
    • Luzzana, C.1    Gerosa, M.2    Riboldi, P.3
  • 162
    • 0028883268 scopus 로고
    • In vitro effect of antiphospholipid antibody-containing sera on basal and gonadotrophin releasing hormone-dependent human chorionic gonadotrophin release by cultured trophoblast cells
    • Di Simone N, De Carolis S, Lanzone A, et al. In vitro effect of antiphospholipid antibody-containing sera on basal and gonadotrophin releasing hormone-dependent human chorionic gonadotrophin release by cultured trophoblast cells. Placenta 1995;16:75.
    • (1995) Placenta , vol.16 , pp. 75
    • Di Simone, N.1    De Carolis, S.2    Lanzone, A.3
  • 163
    • 0035179316 scopus 로고    scopus 로고
    • Monoclonal anti-annexin V antibody inhibits trophoblast gonadotropin secretion and induces syncytiotrophoblast apoptosis
    • Di Simone N, Castellani R, Caliandro D, et al. Monoclonal anti-annexin V antibody inhibits trophoblast gonadotropin secretion and induces syncytiotrophoblast apoptosis. Biol Reprod 2001;65:1766.
    • (2001) Biol Reprod , vol.65 , pp. 1766
    • Di Simone, N.1    Castellani, R.2    Caliandro, D.3
  • 164
    • 0034121236 scopus 로고    scopus 로고
    • Antiphospholipid antibodies affect trophoblast gonadotropin secretion and invasiveness by binding directly and through adhered beta2-glycoprotein I
    • Di Simone N, Meroni PL, del Papa N, et al. Antiphospholipid antibodies affect trophoblast gonadotropin secretion and invasiveness by binding directly and through adhered beta2-glycoprotein I. Arthritis Rheum 2000;43:140.
    • (2000) Arthritis Rheum , vol.43 , pp. 140
    • Di Simone, N.1    Meroni, P.L.2    Del Papa, N.3
  • 165
    • 0030922747 scopus 로고    scopus 로고
    • Human cytotrophoblasts adopt a vascular phenotype as they differentiate. A strategy for successful endovascular invasion?
    • Zhou Y, Fisher SJ, Janatpour M, et al. Human cytotrophoblasts adopt a vascular phenotype as they differentiate. A strategy for successful endovascular invasion? J Clin Invest 1997;99:2139.
    • (1997) J Clin Invest , vol.99 , pp. 2139
    • Zhou, Y.1    Fisher, S.J.2    Janatpour, M.3
  • 166
    • 0343853017 scopus 로고    scopus 로고
    • Integrins and reproductive physiology: Expression and modulation in fertilization, embryogenesis, and implantation
    • Sueoka K, Shiokawa S, Miyazaki T, et al. Integrins and reproductive physiology: Expression and modulation in fertilization, embryogenesis, and implantation. Fertil Steril 1997;67:799.
    • (1997) Fertil Steril , vol.67 , pp. 799
    • Sueoka, K.1    Shiokawa, S.2    Miyazaki, T.3
  • 167
    • 0036009815 scopus 로고    scopus 로고
    • Antiphospholid antibodies regulate the expression of trophoblast cell adhesion molecules
    • Di Simone N, Castellani R, Caliandro D, et al. Antiphospholid antibodies regulate the expression of trophoblast cell adhesion molecules. Fertil Steril 2002;77:805.
    • (2002) Fertil Steril , vol.77 , pp. 805
    • Di Simone, N.1    Castellani, R.2    Caliandro, D.3
  • 168
    • 0031955126 scopus 로고    scopus 로고
    • Familial lupus anticoagulant: A case report and review of the literature
    • Hellan M, Kuhnel E, Speiser W, et al. Familial lupus anticoagulant: A case report and review of the literature. Blood Coagul Fibrinolysis 1998;9:195.
    • (1998) Blood Coagul Fibrinolysis , vol.9 , pp. 195
    • Hellan, M.1    Kuhnel, E.2    Speiser, W.3
  • 169
    • 0033173789 scopus 로고    scopus 로고
    • Correlation between beta2-glycoprotein I valine/leucine247 polymorphism and anti-beta2-glycoproteinI antibodies in patients with primary antiphospholipid syndrome
    • Atsumi T, Tsutsumi A, Amengual O, et al. Correlation between beta2-glycoprotein I valine/leucine247 polymorphism and anti-beta2-glycoproteinI antibodies in patients with primary antiphospholipid syndrome. Rheumatology 1999;38:721.
    • (1999) Rheumatology , vol.38 , pp. 721
    • Atsumi, T.1    Tsutsumi, A.2    Amengual, O.3
  • 170
    • 0033496362 scopus 로고    scopus 로고
    • A role for the polymorphism at position 247 of the beta2-glycoprotein I gene in the generation of anti-beta2-glycoprotein I antibodies in the antiphospholipid syndrome
    • Hirose N, Williams R, Alberts AR, et al. A role for the polymorphism at position 247 of the beta2-glycoprotein I gene in the generation of anti-beta2-glycoprotein I antibodies in the antiphospholipid syndrome. Arthritis Rheum 1999;42:1655.
    • (1999) Arthritis Rheum , vol.42 , pp. 1655
    • Hirose, N.1    Williams, R.2    Alberts, A.R.3
  • 171
    • 0026487489 scopus 로고
    • Major histocompatibility complex associations with primary antiphospholipid syndrome
    • Asherson RA, Doherty DG, Vergani D, et al. Major histocompatibility complex associations with primary antiphospholipid syndrome. Arthritis Rheum 1992;35:124.
    • (1992) Arthritis Rheum , vol.35 , pp. 124
    • Asherson, R.A.1    Doherty, D.G.2    Vergani, D.3
  • 172
    • 0028982254 scopus 로고
    • Association of HLA-DR5 (possibly DRB1*1201) with the primary antiphospholipid syndrome in Mexican patients
    • Vargas-Alarcon G, Granados J, Bekker C, et al. Association of HLA-DR5 (possibly DRB1*1201) with the primary antiphospholipid syndrome in Mexican patients. Arthritis Rheum 1995;38:1340.
    • (1995) Arthritis Rheum , vol.38 , pp. 1340
    • Vargas-Alarcon, G.1    Granados, J.2    Bekker, C.3
  • 173
    • 0028922980 scopus 로고
    • Association between HLA class II antigens and primary antiphospholipid syndrome from the south of Spain
    • Camps MT, Cuadrado MJ, Ocon P, et al. Association between HLA class II antigens and primary antiphospholipid syndrome from the south of Spain. Lupus 1995;4:51.
    • (1995) Lupus , vol.4 , pp. 51
    • Camps, M.T.1    Cuadrado, M.J.2    Ocon, P.3
  • 174
    • 0029681572 scopus 로고    scopus 로고
    • MHC studies of the primary antiphospholipid antibody syndrome and of antiphospholipid antibodies in systemic lupus erythematosus
    • Goldstein R, Moulds JM, Smith CD, et al. MHC studies of the primary antiphospholipid antibody syndrome and of antiphospholipid antibodies in systemic lupus erythematosus. J Rheumatol 1996;23:1173.
    • (1996) J Rheumatol , vol.23 , pp. 1173
    • Goldstein, R.1    Moulds, J.M.2    Smith, C.D.3
  • 175
    • 0031036799 scopus 로고    scopus 로고
    • Relationship of anticardiolipin antibodies and antiphospholipid syndrome to HLA-DR7 in Mexican patients with systemic lupus erythematosus (SLE)
    • Granados J, Vargas-Alarcon G, Drenkard C, et al. Relationship of anticardiolipin antibodies and antiphospholipid syndrome to HLA-DR7 in Mexican patients with systemic lupus erythematosus (SLE). Lupus 1997;6:57.
    • (1997) Lupus , vol.6 , pp. 57
    • Granados, J.1    Vargas-Alarcon, G.2    Drenkard, C.3
  • 176
    • 0042830844 scopus 로고    scopus 로고
    • Increased fibrin polymerization rate in patients with primary antiphospholipid syndrome and systemic lupus erythematosus
    • de Pablo P, Ramirez A, Cortina E, et al. Increased fibrin polymerization rate in patients with primary antiphospholipid syndrome and systemic lupus erythematosus. Clin Appl Thromb Hemost 2003;9:221.
    • (2003) Clin Appl Thromb Hemost , vol.9 , pp. 221
    • De Pablo, P.1    Ramirez, A.2    Cortina, E.3
  • 177
    • 0036433488 scopus 로고    scopus 로고
    • Suppressed intrinsic fibrinolytic activity by monoclonal anti-beta-2 glycoprotein I autoantibodies: Possible mechanism for thrombosis in patients with antiphospholipid syndrome
    • Takeuchi R, Atsumi T, Ieko M, et al. Suppressed intrinsic fibrinolytic activity by monoclonal anti-beta-2 glycoprotein I autoantibodies: Possible mechanism for thrombosis in patients with antiphospholipid syndrome. Br J Haematol 2002;119:781.
    • (2002) Br J Haematol , vol.119 , pp. 781
    • Takeuchi, R.1    Atsumi, T.2    Ieko, M.3
  • 178
    • 0033660836 scopus 로고    scopus 로고
    • Effects of beta2-glycoprotein I and monoclonal anticardiolipin antibodies on extrinsic fibrinolysis
    • Ieko M, Ichikawa K, Atsumi T, et al. Effects of beta2-glycoprotein I and monoclonal anticardiolipin antibodies on extrinsic fibrinolysis. Semin Thromb Hemost 2000;26:85.
    • (2000) Semin Thromb Hemost , vol.26 , pp. 85
    • Ieko, M.1    Ichikawa, K.2    Atsumi, T.3
  • 179
    • 0028266134 scopus 로고
    • Autoantibodies to heparin from patients with antiphospholipid antibody syndrome inhibit formation of antithrombin III-thrombin complexes
    • Shibata S, Harpel PC, Gharavi A, et al. Autoantibodies to heparin from patients with antiphospholipid antibody syndrome inhibit formation of antithrombin III-thrombin complexes. Blood 1994;83:2532.
    • (1994) Blood , vol.83 , pp. 2532
    • Shibata, S.1    Harpel, P.C.2    Gharavi, A.3
  • 180
    • 0242524904 scopus 로고    scopus 로고
    • Recent advances in the diagnosis of antiphospholipid syndrome
    • Chi HS. Recent advances in the diagnosis of antiphospholipid syndrome. Int J Hematol 2002;76 Suppl 2:47.
    • (2002) Int J Hematol , vol.76 , Issue.SUPPL. 2 , pp. 47
    • Chi, H.S.1
  • 181
    • 0028930210 scopus 로고
    • Laboratory diagnosis of antiphospholipid syndromes
    • Reyes H, Dearing L, Bick RL, et al. Laboratory diagnosis of antiphospholipid syndromes. Clin Lab Med 1995;15:85.
    • (1995) Clin Lab Med , vol.15 , pp. 85
    • Reyes, H.1    Dearing, L.2    Bick, R.L.3
  • 182
    • 0031127267 scopus 로고    scopus 로고
    • Antiphospholipid thrombosis syndromes: Etiology, pathophysiology, diagnosis and management
    • Bick RL. Antiphospholipid thrombosis syndromes: Etiology, pathophysiology, diagnosis and management. Int J Hematol 1997;65:193.
    • (1997) Int J Hematol , vol.65 , pp. 193
    • Bick, R.L.1
  • 184
    • 0028070570 scopus 로고
    • Conclusions of the first French workshop of standardization of anticardiolipin antibody determination associated with autoimmune pathology
    • Abuaf N, Meyer O, Laperche S, et al. Conclusions of the first French workshop of standardization of anticardiolipin antibody determination associated with autoimmune pathology. Ann Biol Clin 1994;52:365.
    • (1994) Ann Biol Clin , vol.52 , pp. 365
    • Abuaf, N.1    Meyer, O.2    Laperche, S.3
  • 185
    • 0036780682 scopus 로고    scopus 로고
    • Assessing the usefulness of anticardiolipin antibody assays: A cautious approach is suggested by high variation and limited consensus in multilaboratory testing
    • Favaloro EJ, Silvestrini R. Assessing the usefulness of anticardiolipin antibody assays: A cautious approach is suggested by high variation and limited consensus in multilaboratory testing. Am J Clin Pathol 2002;118:548.
    • (2002) Am J Clin Pathol , vol.118 , pp. 548
    • Favaloro, E.J.1    Silvestrini, R.2
  • 186
    • 0025828109 scopus 로고
    • Guidelines for testing and revised criteria for lupus anticoagulants. SSC Subcommittee for the Standardization of Lupus Anticoagulants
    • Exner T, Triplett DA, Taberner D, et al. Guidelines for testing and revised criteria for lupus anticoagulants. SSC Subcommittee for the Standardization of Lupus Anticoagulants. Thromb Haemost 1991;65:320.
    • (1991) Thromb Haemost , vol.65 , pp. 320
    • Exner, T.1    Triplett, D.A.2    Taberner, D.3
  • 187
    • 0026065097 scopus 로고
    • Evaluation of different mixing study reagents and dilution effect in lupus anticoagulant testing
    • Kaczor DA, Bickford NN, Triplett DA. Evaluation of different mixing study reagents and dilution effect in lupus anticoagulant testing. Am J Clin Pathol 1991;95:408.
    • (1991) Am J Clin Pathol , vol.95 , pp. 408
    • Kaczor, D.A.1    Bickford, N.N.2    Triplett, D.A.3
  • 188
    • 0024833812 scopus 로고
    • The effect of phospholipid on the detection of lupus anticoagulants by the dilute Russell viper venom time
    • Brandt JT, Triplett DA. The effect of phospholipid on the detection of lupus anticoagulants by the dilute Russell viper venom time. Arch Pathol Lab Med 1989;113:1376.
    • (1989) Arch Pathol Lab Med , vol.113 , pp. 1376
    • Brandt, J.T.1    Triplett, D.A.2
  • 189
    • 0036112353 scopus 로고    scopus 로고
    • Reference ranges of the dilute tissue thromboplastin inhibition and dilute Russell's viper venom tests revisited
    • Gerbutavicius R, Fareed J, Messmore HL, et al. Reference ranges of the dilute tissue thromboplastin inhibition and dilute Russell's viper venom tests revisited. Clin Appl Thromb Hemost 2002;8:51.
    • (2002) Clin Appl Thromb Hemost , vol.8 , pp. 51
    • Gerbutavicius, R.1    Fareed, J.2    Messmore, H.L.3
  • 190
    • 0032915459 scopus 로고    scopus 로고
    • The sensitivity and specificity of commercial reagents for the detection of lupus anticoagulant show marked differences in performance between photo-optical and mechanical coagulometers
    • Lawrie AS, Mackie IJ, Purdy G, et al. The sensitivity and specificity of commercial reagents for the detection of lupus anticoagulant show marked differences in performance between photo-optical and mechanical coagulometers. Thromb Haemost 1999;81:758.
    • (1999) Thromb Haemost , vol.81 , pp. 758
    • Lawrie, A.S.1    Mackie, I.J.2    Purdy, G.3
  • 191
    • 0020530155 scopus 로고
    • Laboratory diagnosis of lupus inhibitors: A comparison of the tissue thromboplastin inhibition procedure with a new platelet neutralization procedure
    • Triplett DA, Brandt JT, Kaczor D, et al. Laboratory diagnosis of lupus inhibitors: A comparison of the tissue thromboplastin inhibition procedure with a new platelet neutralization procedure. Am J Clin Pathol 1983;79:678.
    • (1983) Am J Clin Pathol , vol.79 , pp. 678
    • Triplett, D.A.1    Brandt, J.T.2    Kaczor, D.3
  • 192
    • 0026578689 scopus 로고
    • A new lupus anticoagulant neutralization test based on platelet-derived vesicles
    • Arnout J, Huybrechts E, Vanrusselt M, et al. A new lupus anticoagulant neutralization test based on platelet-derived vesicles. Br J Haematol 1992;80:341.
    • (1992) Br J Haematol , vol.80 , pp. 341
    • Arnout, J.1    Huybrechts, E.2    Vanrusselt, M.3
  • 193
    • 0027750894 scopus 로고
    • The Textarin/Ecarin ratio: A confirmatory test for lupus anticoagulants
    • Triplett DA, Stocker KF, Unger GA, et al. The Textarin/Ecarin ratio: A confirmatory test for lupus anticoagulants. Thromb Haemost 1993;70:925.
    • (1993) Thromb Haemost , vol.70 , pp. 925
    • Triplett, D.A.1    Stocker, K.F.2    Unger, G.A.3
  • 194
    • 0028125876 scopus 로고
    • Comparison of a platelet neutralization procedure with a hexagonal phase phospholipid neutralization assay as confirmatory tests for the presence of lupus anticoagulants
    • Reber G, Roisin JP, Migaud M, et al. Comparison of a platelet neutralization procedure with a hexagonal phase phospholipid neutralization assay as confirmatory tests for the presence of lupus anticoagulants. Thromb Res 1994;73:131.
    • (1994) Thromb Res , vol.73 , pp. 131
    • Reber, G.1    Roisin, J.P.2    Migaud, M.3
  • 195
    • 0026697923 scopus 로고
    • Silica clotting time (SCT) as a screening and confirmatory test for detection of the lupus anticoagulants
    • Chantarangkul V, Tripodi A, Arbini A, et al. Silica clotting time (SCT) as a screening and confirmatory test for detection of the lupus anticoagulants. Thromb Res 1992;67:355.
    • (1992) Thromb Res , vol.67 , pp. 355
    • Chantarangkul, V.1    Tripodi, A.2    Arbini, A.3
  • 196
    • 0028983882 scopus 로고
    • Kaolin clotting time and dilute Russell's viper venom time distinguish between prothrombin-dependent and beta 2-glycoprotein I-dependent antiphospholipid antibodies
    • Galli M, Finazzi G, Bevers EM, et al. Kaolin clotting time and dilute Russell's viper venom time distinguish between prothrombin-dependent and beta 2-glycoprotein I-dependent antiphospholipid antibodies. Blood 1995;86:617.
    • (1995) Blood , vol.86 , pp. 617
    • Galli, M.1    Finazzi, G.2    Bevers, E.M.3
  • 197
    • 0032989305 scopus 로고    scopus 로고
    • dRVVT is more sensitive than KCT or TTI for detecting lupus anticoagulant activity of anti-beta2-glycoprotein I autoantibodies
    • Pengo V, Biasiolo A, Rampazzo P, et al. dRVVT is more sensitive than KCT or TTI for detecting lupus anticoagulant activity of anti-beta2-glycoprotein I autoantibodies. Thromb Haemost 1999;81:256.
    • (1999) Thromb Haemost , vol.81 , pp. 256
    • Pengo, V.1    Biasiolo, A.2    Rampazzo, P.3
  • 198
    • 0037087224 scopus 로고    scopus 로고
    • Dilute prothrombin time-based lupus ratio test. Integrated LA testing with recombinant tissue thromboplastin
    • Liestol S, Jacobsen EM, Wisloff F. Dilute prothrombin time-based lupus ratio test. Integrated LA testing with recombinant tissue thromboplastin. Thromb Res 2002;105:177.
    • (2002) Thromb Res , vol.105 , pp. 177
    • Liestol, S.1    Jacobsen, E.M.2    Wisloff, F.3
  • 199
    • 0027964803 scopus 로고
    • The Taipan snake venom time: A new test for lupus anticoagulant
    • Rooney AM, McNally T, Mackie IJ, et al. The Taipan snake venom time:a new test for lupus anticoagulant. J Clin Pathol 1994;47:497.
    • (1994) J Clin Pathol , vol.47 , pp. 497
    • Rooney, A.M.1    McNally, T.2    Mackie, I.J.3
  • 200
    • 0035992634 scopus 로고    scopus 로고
    • MIXCONLA: A precise, sensitive and specific aPTT-based assay for detection of lupus anticoagulant
    • Lindhoff-Last E, Humpich M, Schmitt J, et al. MIXCONLA: A precise, sensitive and specific aPTT-based assay for detection of lupus anticoagulant. Clin Appl Thromb Hemost 2002;8:163.
    • (2002) Clin Appl Thromb Hemost , vol.8 , pp. 163
    • Lindhoff-Last, E.1    Humpich, M.2    Schmitt, J.3
  • 201
    • 0033826834 scopus 로고    scopus 로고
    • Conceptions and misconceptions in testing for lupus anticoagulants
    • Exner T. Conceptions and misconceptions in testing for lupus anticoagulants. J Autoimmun 2000;15:179.
    • (2000) J Autoimmun , vol.15 , pp. 179
    • Exner, T.1
  • 202
    • 0024596105 scopus 로고
    • The laboratory diagnosis of lupus anticoagulants
    • Lazarchick J, Kizer J. The laboratory diagnosis of lupus anticoagulants. Arch Pathol Lab Med 1989;113:177.
    • (1989) Arch Pathol Lab Med , vol.113 , pp. 177
    • Lazarchick, J.1    Kizer, J.2
  • 203
    • 0036743755 scopus 로고    scopus 로고
    • Antiphospholipid antibodies in a heterogeneous group of patients: Experience from a central laboratory
    • Mader R, Ziporen L, Mader R, et al. Antiphospholipid antibodies in a heterogeneous group of patients: Experience from a central laboratory. Clin Rheumatol 2002;21:386.
    • (2002) Clin Rheumatol , vol.21 , pp. 386
    • Mader, R.1    Ziporen, L.2    Mader, R.3
  • 204
    • 0033841130 scopus 로고    scopus 로고
    • Coagulation tests and anti-phospholipid antibodies in patients positive for lupus anticoagulant
    • Sakakura M, Wada H, Watanabe R, et al. Coagulation tests and anti-phospholipid antibodies in patients positive for lupus anticoagulant. Clin Appl Thromb Hemost 2000;6:144.
    • (2000) Clin Appl Thromb Hemost , vol.6 , pp. 144
    • Sakakura, M.1    Wada, H.2    Watanabe, R.3
  • 205
    • 0036089170 scopus 로고    scopus 로고
    • Testing strategies for diagnosing lupus anticoagulant: Decision analysis
    • Segal JB, Lehmann HP, Petri M, et al. Testing strategies for diagnosing lupus anticoagulant: Decision analysis. Am J Hematol 2002;70:195.
    • (2002) Am J Hematol , vol.70 , pp. 195
    • Segal, J.B.1    Lehmann, H.P.2    Petri, M.3
  • 206
    • 0037492333 scopus 로고    scopus 로고
    • Laboratory diagnosis of the antiphospholipid syndrome
    • Wisloff F, Jacobsen EM, Liestol S. Laboratory diagnosis of the antiphospholipid syndrome. Thromb Res 2002;108:263.
    • (2002) Thromb Res , vol.108 , pp. 263
    • Wisloff, F.1    Jacobsen, E.M.2    Liestol, S.3
  • 207
    • 0030805607 scopus 로고    scopus 로고
    • Antiphospholipid antibodies: Predictive value of laboratory tests
    • Galli M, Finazzi G, Barbui T. Antiphospholipid antibodies: Predictive value of laboratory tests. Thromb Haemost 1997;78:75.
    • (1997) Thromb Haemost , vol.78 , pp. 75
    • Galli, M.1    Finazzi, G.2    Barbui, T.3
  • 208
    • 0034528912 scopus 로고    scopus 로고
    • Lupus anticoagulants and thrombosis: Clinical association of different coagulation and immunologic tests
    • Galli M, Dlott J, Norbis F, et al. Lupus anticoagulants and thrombosis: Clinical association of different coagulation and immunologic tests. Thromb Haemost 2000;84:1012.
    • (2000) Thromb Haemost , vol.84 , pp. 1012
    • Galli, M.1    Dlott, J.2    Norbis, F.3
  • 209
    • 0036092824 scopus 로고    scopus 로고
    • Phospholipid autoantibodies and the antiphospholipid antibody syndrome: Diagnostic accuracy of 23 methods studied by variation in ROC curves with number of clinical manifestations
    • Wasmuth JC, Minarro D, Homrighausen A, et al. Phospholipid autoantibodies and the antiphospholipid antibody syndrome: Diagnostic accuracy of 23 methods studied by variation in ROC curves with number of clinical manifestations. Clin Chem 2002;48:1004.
    • (2002) Clin Chem , vol.48 , pp. 1004
    • Wasmuth, J.C.1    Minarro, D.2    Homrighausen, A.3
  • 210
    • 0037402312 scopus 로고    scopus 로고
    • Antiphospholipid antibodies: Discovery, definitions, detection and disease
    • McIntyre JA, Wagenknecht DR, Faulk WP. Antiphospholipid antibodies: Discovery, definitions, detection and disease. Prog Lipid Res 2003;42:176.
    • (2003) Prog Lipid Res , vol.42 , pp. 176
    • McIntyre, J.A.1    Wagenknecht, D.R.2    Faulk, W.P.3
  • 211
    • 0034846762 scopus 로고    scopus 로고
    • Optimising testing for phospholipid antibodies
    • Helbert M, Bodger S, Cavenagh J, et al. Optimising testing for phospholipid antibodies. J Clin Pathol 2001; 54:693.
    • (2001) J Clin Pathol , vol.54 , pp. 693
    • Helbert, M.1    Bodger, S.2    Cavenagh, J.3
  • 212
    • 0037297397 scopus 로고    scopus 로고
    • Central nervous system involvement in the antiphospholipid (Hughes) syndrome
    • Sanna G, Bertolaccini ML, Cuadrado MJ, et al. Central nervous system involvement in the antiphospholipid (Hughes) syndrome. Rheumatology (Oxford) 2003; 42:200.
    • (2003) Rheumatology (Oxford) , vol.42 , pp. 200
    • Sanna, G.1    Bertolaccini, M.L.2    Cuadrado, M.J.3
  • 214
    • 0034858414 scopus 로고    scopus 로고
    • Hughes (antiphospholipid) syndrome. Clinical features
    • Cuadrado MJ, Hughes GR. Hughes (antiphospholipid) syndrome. Clinical features. Rheum Dis Clin North Am 2001;27:507.
    • (2001) Rheum Dis Clin North Am , vol.27 , pp. 507
    • Cuadrado, M.J.1    Hughes, G.R.2
  • 215
    • 0029790534 scopus 로고    scopus 로고
    • Antiphospholipid antibodies and retinal vascular disease
    • Dunn JP, Noorily SW, Petri M, et al. Antiphospholipid antibodies and retinal vascular disease. Lupus 1996;5:313.
    • (1996) Lupus , vol.5 , pp. 313
    • Dunn, J.P.1    Noorily, S.W.2    Petri, M.3
  • 216
    • 0028881545 scopus 로고
    • Ocular vasoocclusive disease in primary antiphospholipid syndrome
    • Castanon C, Amigo MC, Banales JL, et al. Ocular vasoocclusive disease in primary antiphospholipid syndrome. Ophthalmology 1995;102:256.
    • (1995) Ophthalmology , vol.102 , pp. 256
    • Castanon, C.1    Amigo, M.C.2    Banales, J.L.3
  • 217
    • 0031951492 scopus 로고    scopus 로고
    • Sudden sensorineural hearing loss in patients with systemic lupus erythematosus or lupus-like syndromes and antiphospholipid antibodies
    • Naarendorp M, Spiera H. Sudden sensorineural hearing loss in patients with systemic lupus erythematosus or lupus-like syndromes and antiphospholipid antibodies. J Rheumatol 1998;25:589.
    • (1998) J Rheumatol , vol.25 , pp. 589
    • Naarendorp, M.1    Spiera, H.2
  • 218
    • 0026438741 scopus 로고
    • Cardiac manifestations of the antiphospholipid syndrome
    • Kaplan SD, Chartash EK, Pizzarello RA, et al. Cardiac manifestations of the antiphospholipid syndrome. Am Heart J 1992;124:1331.
    • (1992) Am Heart J , vol.124 , pp. 1331
    • Kaplan, S.D.1    Chartash, E.K.2    Pizzarello, R.A.3
  • 219
    • 0026254706 scopus 로고
    • High prevalence of significant heart valve lesions in patients with the 'primary' antiphospholipid syndrome
    • Cervera R, Khamashta MA, Font J, et al. High prevalence of significant heart valve lesions in patients with the 'primary' antiphospholipid syndrome. Lupus 1991;1:43.
    • (1991) Lupus , vol.1 , pp. 43
    • Cervera, R.1    Khamashta, M.A.2    Font, J.3
  • 220
    • 0036548143 scopus 로고    scopus 로고
    • Cardiac manifestations of the antiphospholipid antibody syndrome: A review
    • Nayak AK, Komatireddy G. Cardiac manifestations of the antiphospholipid antibody syndrome: A review. Mo Med 2002;99:171.
    • (2002) Mo Med , vol.99 , pp. 171
    • Nayak, A.K.1    Komatireddy, G.2
  • 221
    • 0028362429 scopus 로고
    • Antiphospholipid antibodies in coronary artery disease: A review
    • Baker WF Jr, Bick RL. Antiphospholipid antibodies in coronary artery disease: A review. Semin Thromb Hemost 1994;20:27.
    • (1994) Semin Thromb Hemost , vol.20 , pp. 27
    • Baker Jr., W.F.1    Bick, R.L.2
  • 222
    • 0026719074 scopus 로고
    • Myocardial infarction caused by cardiac microvasculopathy in a patient with the primary antiphospholipid syndrome
    • Kattwinkel N, Villanueva AG, Labib SB, et al. Myocardial infarction caused by cardiac microvasculopathy in a patient with the primary antiphospholipid syndrome. Ann Intern Med 1992;116:974.
    • (1992) Ann Intern Med , vol.116 , pp. 974
    • Kattwinkel, N.1    Villanueva, A.G.2    Labib, S.B.3
  • 224
    • 0036177664 scopus 로고    scopus 로고
    • The lung in the antiphospholipid syndrome
    • Espinosa G, Cervera R, Font J, et al. The lung in the antiphospholipid syndrome. Ann Rheum Dis 2002;61:195.
    • (2002) Ann Rheum Dis , vol.61 , pp. 195
    • Espinosa, G.1    Cervera, R.2    Font, J.3
  • 225
    • 0033834480 scopus 로고    scopus 로고
    • Kidney involvement in the antiphospholipid syndrome
    • Nochy D, Daugas E, Huong DL, et al. Kidney involvement in the antiphospholipid syndrome. J Autoimmun 2000;15:127.
    • (2000) J Autoimmun , vol.15 , pp. 127
    • Nochy, D.1    Daugas, E.2    Huong, D.L.3
  • 226
    • 0036016093 scopus 로고    scopus 로고
    • Nephrological and obstetric complications of the antiphospholipid syndrome
    • Isom R, Nickolas TL, Radhakrishnan J. Nephrological and obstetric complications of the antiphospholipid syndrome. Expert Opin Investig Drugs 2002;11:819.
    • (2002) Expert Opin Investig Drugs , vol.11 , pp. 819
    • Isom, R.1    Nickolas, T.L.2    Radhakrishnan, J.3
  • 227
    • 0035885922 scopus 로고    scopus 로고
    • Antiphospholipid antibodies and antiphospholipid syndrome in patients presenting with immune thrombocytopenic purpura: A prospective cohort study
    • Diz-Kucukkaya R, Hacihanefioglu A, Yenerel M, et al. Antiphospholipid antibodies and antiphospholipid syndrome in patients presenting with immune thrombocytopenic purpura: A prospective cohort study. Blood 2001;98:1760.
    • (2001) Blood , vol.98 , pp. 1760
    • Diz-Kucukkaya, R.1    Hacihanefioglu, A.2    Yenerel, M.3
  • 228
    • 0037340571 scopus 로고    scopus 로고
    • Adrenal involvement in the antiphospholipid syndrome: Clinical and immunologic characteristics of 86 patients
    • Espinosa G, Santos E, Cervera R, et al. Adrenal involvement in the antiphospholipid syndrome: Clinical and immunologic characteristics of 86 patients. Medicine 2003;82:106.
    • (2003) Medicine , vol.82 , pp. 106
    • Espinosa, G.1    Santos, E.2    Cervera, R.3
  • 229
    • 0037334595 scopus 로고    scopus 로고
    • Asymptomatic avascular necrosis in patients with primary antiphospholipid syndrome in the absence of corticosteroid use: A prospective study by magnetic resonance imaging
    • Tektonidou MG, Malagari K, Vlachoyiannopoulos PG, et al. Asymptomatic avascular necrosis in patients with primary antiphospholipid syndrome in the absence of corticosteroid use: A prospective study by magnetic resonance imaging. Arthritis Rheum 2003;48:732.
    • (2003) Arthritis Rheum , vol.48 , pp. 732
    • Tektonidou, M.G.1    Malagari, K.2    Vlachoyiannopoulos, P.G.3
  • 231
    • 0033512274 scopus 로고    scopus 로고
    • International consensus statement on preliminary classification criteria for definite antiphospholipid syndrome: Report of an international workshop
    • Wilson WA, Gharavi AE, Koike T, et al. International consensus statement on preliminary classification criteria for definite antiphospholipid syndrome: Report of an international workshop. Arthritis Rheum 1999; 42:1309.
    • (1999) Arthritis Rheum , vol.42 , pp. 1309
    • Wilson, W.A.1    Gharavi, A.E.2    Koike, T.3
  • 232
    • 0031787008 scopus 로고    scopus 로고
    • The catastrophic antiphospholipid syndrome, 1998. A review of the clinical features, possible pathogenesis and treatment
    • Asherson RA. The catastrophic antiphospholipid syndrome, 1998. A review of the clinical features, possible pathogenesis and treatment. Lupus 1998;7 Suppl 2:S55.
    • (1998) Lupus , vol.7 , Issue.SUPPL. 2
    • Asherson, R.A.1
  • 233
  • 234
    • 0021029327 scopus 로고
    • Anticardiolipin antibodies: Detection by radioimmunoassay and association with thrombosis in systemic lupus erythematosus
    • Harris EN, Gharavi AE, Boey ML, et al. Anticardiolipin antibodies: Detection by radioimmunoassay and association with thrombosis in systemic lupus erythematosus. Lancet 1983;ii:1211.
    • (1983) Lancet , vol.2 , pp. 1211
    • Harris, E.N.1    Gharavi, A.E.2    Boey, M.L.3
  • 235
    • 0030457493 scopus 로고    scopus 로고
    • Lupus anticoagulant is the strongest risk factor for both venous and arterial thrombosis in patients with systemic lupus erythematosus
    • Horbach DA, Oort EV, Donders RAJM, et al. Lupus anticoagulant is the strongest risk factor for both venous and arterial thrombosis in patients with systemic lupus erythematosus. Thromb Haemost 1996;76:916.
    • (1996) Thromb Haemost , vol.76 , pp. 916
    • Horbach, D.A.1    Oort, E.V.2    Donders, R.A.J.M.3
  • 236
    • 0032776951 scopus 로고    scopus 로고
    • Elevated anticardiolipin antibody titer is a stroke risk factor in a multiethnic population independent of isotype or degree of positivity
    • Tuhrim S, Rand JH, Wu XX, et al. Elevated anticardiolipin antibody titer is a stroke risk factor in a multiethnic population independent of isotype or degree of positivity. Stroke 1999;30:1561.
    • (1999) Stroke , vol.30 , pp. 1561
    • Tuhrim, S.1    Rand, J.H.2    Wu, X.X.3
  • 237
    • 0030869155 scopus 로고    scopus 로고
    • Association between IgM anticardiolipin antibodies and deep venous thrombosis in patients without systemic lupus erythematosus
    • Oger E, Lernyer C, Dueymes M, et al. Association between IgM anticardiolipin antibodies and deep venous thrombosis in patients without systemic lupus erythematosus. Lupus 1997;6:455.
    • (1997) Lupus , vol.6 , pp. 455
    • Oger, E.1    Lernyer, C.2    Dueymes, M.3
  • 238
    • 0031919292 scopus 로고    scopus 로고
    • Anticardiolipin antibodies predict early recurrence of thromboembolism and death among patients with venous thromboembolism following anticoagulant therapy. Duration of Anticoagulation Study Group
    • Schulman S, Svenungsson E, Granqvist S. Anticardiolipin antibodies predict early recurrence of thromboembolism and death among patients with venous thromboembolism following anticoagulant therapy. Duration of Anticoagulation Study Group. Am J Med 1998;104:332.
    • (1998) Am J Med , vol.104 , pp. 332
    • Schulman, S.1    Svenungsson, E.2    Granqvist, S.3
  • 239
    • 0035347253 scopus 로고    scopus 로고
    • Relationship between antiphospholipid antibodies and progression of lower extremity arterial occlusive disease after lower extremity bypass operations
    • Lam EY, Taylor LM Jr, Landry GJ, et al. Relationship between antiphospholipid antibodies and progression of lower extremity arterial occlusive disease after lower extremity bypass operations. J Vasc Surg 2001;33:976.
    • (2001) J Vasc Surg , vol.33 , pp. 976
    • Lam, E.Y.1    Taylor Jr., L.M.2    Landry, G.J.3
  • 240
    • 0029938039 scopus 로고    scopus 로고
    • Anticardiolipin antibodies: Clinical consequences of "low titers"
    • Silver RM, Porter TF, van Leeuween I, et al. Anticardiolipin antibodies: Clinical consequences of "low titers." Obstet Gynecol 1996;87:494.
    • (1996) Obstet Gynecol , vol.87 , pp. 494
    • Silver, R.M.1    Porter, T.F.2    Van Leeuween, I.3
  • 241
    • 0037370733 scopus 로고    scopus 로고
    • Lupus anticoagulants are stronger risk factors for thrombosis than anticardiolipin antibodies in the antiphospholipid syndrome: A systematic review of the literature
    • Galli M, Luciani D, Bertolini G, et al. Lupus anticoagulants are stronger risk factors for thrombosis than anticardiolipin antibodies in the antiphospholipid syndrome: A systematic review of the literature. Blood 2003;101:1827.
    • (2003) Blood , vol.101 , pp. 1827
    • Galli, M.1    Luciani, D.2    Bertolini, G.3
  • 242
    • 0033008989 scopus 로고    scopus 로고
    • Antiphospholipid (Hughes') syndrome in African-Americans: IgA aCL and abeta2 glycoprotein-I is the most frequent isotype
    • Diri E, Cucurull E, Gharavi AE, et al. Antiphospholipid (Hughes') syndrome in African-Americans: IgA aCL and abeta2 glycoprotein-I is the most frequent isotype. Lupus 1999;8:263.
    • (1999) Lupus , vol.8 , pp. 263
    • Diri, E.1    Cucurull, E.2    Gharavi, A.E.3
  • 243
    • 0031921483 scopus 로고    scopus 로고
    • High frequency of abnormal levels of IgA anti-beta2-glycoprotein I antibodies in patients with systemic lupus erythematosus: Relationship with antiphospholipid syndrome
    • Fanopoulos D, Teodorescu MR, Varga J, et al. High frequency of abnormal levels of IgA anti-beta2-glycoprotein I antibodies in patients with systemic lupus erythematosus: Relationship with antiphospholipid syndrome. J Rheumatol 1998;25:675.
    • (1998) J Rheumatol , vol.25 , pp. 675
    • Fanopoulos, D.1    Teodorescu, M.R.2    Varga, J.3
  • 244
    • 0035204249 scopus 로고    scopus 로고
    • The value of IgA antiphospholipid testing for diagnosis of antiphospholipid (Hughes) syndrome in systemic lupus erythematosus
    • Bertolaccini ML, Atsumi T, Escudero Contreras A, et al. The value of IgA antiphospholipid testing for diagnosis of antiphospholipid (Hughes) syndrome in systemic lupus erythematosus. J Rheumatol 2001;28:2637.
    • (2001) J Rheumatol , vol.28 , pp. 2637
    • Bertolaccini, M.L.1    Atsumi, T.2    Escudero Contreras, A.3
  • 245
    • 0031886471 scopus 로고    scopus 로고
    • IgA anticardiolipin antibodies-relation with other antiphospholipid antibodies and clinical significance
    • Selva-O'Callaghan A, Ordi-Ros J, Monegal-Ferran F, et al. IgA anticardiolipin antibodies-relation with other antiphospholipid antibodies and clinical significance. Thromb Haemost 1998;79:282.
    • (1998) Thromb Haemost , vol.79 , pp. 282
    • Selva-O'Callaghan, A.1    Ordi-Ros, J.2    Monegal-Ferran, F.3
  • 246
    • 0028060343 scopus 로고
    • Anticardiolipin antibodies in an unselected stroke population
    • Muir KW, Squire IB, Alwan W, et al. Anticardiolipin antibodies in an unselected stroke population. Lancet 1994;344:452.
    • (1994) Lancet , vol.344 , pp. 452
    • Muir, K.W.1    Squire, I.B.2    Alwan, W.3
  • 247
    • 0036454495 scopus 로고    scopus 로고
    • Anticardiolipin antibodies as a risk factor for venous thromboembolism in a population-based prospective study
    • Runchey SS, Folsom AR, Tsai MY, et al. Anticardiolipin antibodies as a risk factor for venous thromboembolism in a population-based prospective study. Br J Haematol 2002;119:1005.
    • (2002) Br J Haematol , vol.119 , pp. 1005
    • Runchey, S.S.1    Folsom, A.R.2    Tsai, M.Y.3
  • 248
    • 0026597320 scopus 로고
    • Antiphospholipid antibodies after myocardial infarction and their relation to mortality, reinfarction, and non-haemorrhagic stroke
    • Sletnes KE, Smith P, Abdelnoor M, et al. Antiphospholipid antibodies after myocardial infarction and their relation to mortality, reinfarction, and non-haemorrhagic stroke. Lancet 1992;339:451.
    • (1992) Lancet , vol.339 , pp. 451
    • Sletnes, K.E.1    Smith, P.2    Abdelnoor, M.3
  • 249
    • 0030885477 scopus 로고    scopus 로고
    • Antiphospholipid syndrome without antiphospholipid antibodies at the time of the thrombotic event: Transient 'seronegative' antiphospholipid syndrome?
    • Miret C, Cervera R, Reverter JC, et al. Antiphospholipid syndrome without antiphospholipid antibodies at the time of the thrombotic event: Transient 'seronegative' antiphospholipid syndrome? Clin Exp Rheumatol 1997;15:541.
    • (1997) Clin Exp Rheumatol , vol.15 , pp. 541
    • Miret, C.1    Cervera, R.2    Reverter, J.C.3
  • 250
    • 0033830259 scopus 로고    scopus 로고
    • Which are best biological markers of the antiphospolipid syndrome?
    • Carreras LO, Forastiero RR, Martinuzzo ME. Which are best biological markers of the antiphospolipid syndrome? J Autoimmun 2000;15:163.
    • (2000) J Autoimmun , vol.15 , pp. 163
    • Carreras, L.O.1    Forastiero, R.R.2    Martinuzzo, M.E.3
  • 251
    • 0029806347 scopus 로고    scopus 로고
    • Factor V Leiden, antiphospholipid antibodies and thrombosis in systemic lupus erythematosus
    • Fijnheer R, Horbach DA, Donders RC, et al. Factor V Leiden, antiphospholipid antibodies and thrombosis in systemic lupus erythematosus. Thromb Haemost 1996;76:514.
    • (1996) Thromb Haemost , vol.76 , pp. 514
    • Fijnheer, R.1    Horbach, D.A.2    Donders, R.C.3
  • 252
    • 0028822703 scopus 로고
    • Antiphospholipid antibodies and venous thromboembolism
    • Ginsberg JS, Wells PS, Brill-Edwards P, et al. Antiphospholipid antibodies and venous thromboembolism. Blood 1995;86:3685.
    • (1995) Blood , vol.86 , pp. 3685
    • Ginsberg, J.S.1    Wells, P.S.2    Brill-Edwards, P.3
  • 253
    • 0031982693 scopus 로고    scopus 로고
    • Meta-analysis of the risk of venous thrombosis in individuals with antiphospholipid antibodies without underlying autoimmune disease or previous thrombosis
    • Wahl DG, Guillemin F, de Maistre E, et al. Meta-analysis of the risk of venous thrombosis in individuals with antiphospholipid antibodies without underlying autoimmune disease or previous thrombosis. Lupus 1998;7:15.
    • (1998) Lupus , vol.7 , pp. 15
    • Wahl, D.G.1    Guillemin, F.2    De Maistre, E.3
  • 254
    • 0030779955 scopus 로고    scopus 로고
    • Risk for venous thrombosis related to antiphospholipid antibodies in systemic lupus erythematosus-a meta-analysis
    • Wahl DG, Guillemin F, de Maistre E, et al. Risk for venous thrombosis related to antiphospholipid antibodies in systemic lupus erythematosus-a meta-analysis. Lupus 1997;6:467.
    • (1997) Lupus , vol.6 , pp. 467
    • Wahl, D.G.1    Guillemin, F.2    De Maistre, E.3
  • 255
    • 0030589375 scopus 로고    scopus 로고
    • The anti-beta2-glycoprotein I activity in human anti-phospholipid syndrome sera is due to monoreactive low-affinity autoantibodies directed to epitopes located on native beta2-glycoprotein I and preserved during species' evolution
    • Tincani A, Spatola L, Prati E, et al. The anti-beta2-glycoprotein I activity in human anti-phospholipid syndrome sera is due to monoreactive low-affinity autoantibodies directed to epitopes located on native beta2-glycoprotein I and preserved during species' evolution. J Immunol 1996;157:5732.
    • (1996) J Immunol , vol.157 , pp. 5732
    • Tincani, A.1    Spatola, L.2    Prati, E.3
  • 256
    • 0029897454 scopus 로고    scopus 로고
    • Reactivity to beta 2 glycoprotein I clearly differentiates anticardiolipin antibodies from antiphospholipid syndrome and syphilis
    • Forastiero RR, Martinuzzo ME, Kordich LC, et al. Reactivity to beta 2 glycoprotein I clearly differentiates anticardiolipin antibodies from antiphospholipid syndrome and syphilis. Thromb Haemost 1996;75:717.
    • (1996) Thromb Haemost , vol.75 , pp. 717
    • Forastiero, R.R.1    Martinuzzo, M.E.2    Kordich, L.C.3
  • 257
    • 0030878781 scopus 로고    scopus 로고
    • The antiphospholipid/cofactor syndromes. II. A variant in patients with systemic lupus erythematosus with antibodies to beta 2-glycoprotein I but no antibodies detectable in standard antiphospholipid assays
    • Alarcon-Segovia D, Mestanza M, Cabiedes J, et al. The antiphospholipid/cofactor syndromes. II. A variant in patients with systemic lupus erythematosus with antibodies to beta 2-glycoprotein I but no antibodies detectable in standard antiphospholipid assays. J Rheumatol 1997;24:1545.
    • (1997) J Rheumatol , vol.24 , pp. 1545
    • Alarcon-Segovia, D.1    Mestanza, M.2    Cabiedes, J.3
  • 258
    • 0030469470 scopus 로고    scopus 로고
    • Specificity of ELISA for antibody to beta 2-glycoprotein I in patients with antiphospholipid syndrome
    • Amengual O, Atsumi T, Khamashta MA, et al. Specificity of ELISA for antibody to beta 2-glycoprotein I in patients with antiphospholipid syndrome. Br J Rheumatol 1996;35:1239.
    • (1996) Br J Rheumatol , vol.35 , pp. 1239
    • Amengual, O.1    Atsumi, T.2    Khamashta, M.A.3
  • 259
    • 0031014695 scopus 로고    scopus 로고
    • The association of antibodies to beta 2 glycoprotein I with the antiphospholipid syndrome: A meta-analysis
    • Najmey SS, Keil LB, Adib DY, et al. The association of antibodies to beta 2 glycoprotein I with the antiphospholipid syndrome: A meta-analysis. Ann Clin Lab Sci 1997;27:41.
    • (1997) Ann Clin Lab Sci , vol.27 , pp. 41
    • Najmey, S.S.1    Keil, L.B.2    Adib, D.Y.3
  • 260
    • 0028866838 scopus 로고
    • Clinical manifestations of the antiphospholipid syndrome in patients with systemic lupus erythematosus associate more strongly with anti-beta 2-glycoprotein-I than with antiphospholipid antibodies
    • Cabiedes J, Cabral AR, Alarcon-Segovia D. Clinical manifestations of the antiphospholipid syndrome in patients with systemic lupus erythematosus associate more strongly with anti-beta 2-glycoprotein-I than with antiphospholipid antibodies. J Rheumatol 1995;22:1899.
    • (1995) J Rheumatol , vol.22 , pp. 1899
    • Cabiedes, J.1    Cabral, A.R.2    Alarcon-Segovia, D.3
  • 261
    • 0029834239 scopus 로고    scopus 로고
    • Comparison of an enzyme-linked immunosorbent assay for antibodies to beta2-glycoprotein I and a conventional anticardiolipin immunoassay
    • Roubey RA, Maldonado MA, Byrd SN. Comparison of an enzyme-linked immunosorbent assay for antibodies to beta2-glycoprotein I and a conventional anticardiolipin immunoassay. Arthritis Rheum 1996;39:1606.
    • (1996) Arthritis Rheum , vol.39 , pp. 1606
    • Roubey, R.A.1    Maldonado, M.A.2    Byrd, S.N.3
  • 262
    • 0029586037 scopus 로고
    • Increased levels of beta 2 glycoprotein-I antigen and beta 2 glycoprotein-Ibinding antibodies are associated with a history of thromboembolic complicationsin patients with SLE and primary antiphospholipid syndrome
    • McNally T, Mackie IJ, Machin SJ, et al. Increased levels of beta 2 glycoprotein-I antigen and beta 2 glycoprotein-Ibinding antibodies are associated with a history of thromboembolic complicationsin patients with SLE and primary antiphospholipid syndrome. Br J Rheumatol 1995;34:1031.
    • (1995) Br J Rheumatol , vol.34 , pp. 1031
    • McNally, T.1    Mackie, I.J.2    Machin, S.J.3
  • 263
    • 0036845613 scopus 로고    scopus 로고
    • Anti-beta2-glycoprotein I anti-prothrombin antibodies in antiphospholipid-negative patients with thrombosis: A case control study
    • Previtali S, Barbui T, Galli M. Anti-beta2-glycoprotein I and anti-prothrombin antibodies in antiphospholipid-negative patients with thrombosis: A case control study. Thromb Haemost 2002;88:729.
    • (2002) Thromb Haemost , vol.88 , pp. 729
    • Previtali, S.1    Barbui, T.2    Galli, M.3
  • 264
    • 0032588145 scopus 로고    scopus 로고
    • Do antibodies to beta2-glycoprotein 1 contribute to the better characterization of the antiphospholipid syndrome?
    • Detkova D, Gil-Aguado A, Lavilla P, et al. Do antibodies to beta2-glycoprotein 1 contribute to the better characterization of the antiphospholipid syndrome? Lupus 1999;8:430.
    • (1999) Lupus , vol.8 , pp. 430
    • Detkova, D.1    Gil-Aguado, A.2    Lavilla, P.3
  • 265
    • 0033625356 scopus 로고    scopus 로고
    • IgG anti-beta2-glycoprotein I antibodies in adult patients with systemic lupus erythematosus: Prevalence and diagnostic value for the antiphospholipid syndrome
    • Tubach F, Hayem G, Marchand JL, et al. IgG anti-beta2-glycoprotein I antibodies in adult patients with systemic lupus erythematosus: Prevalence and diagnostic value for the antiphospholipid syndrome. J Rheumatol 2000; 27:1437.
    • (2000) J Rheumatol , vol.27 , pp. 1437
    • Tubach, F.1    Hayem, G.2    Marchand, J.L.3
  • 266
    • 0033256156 scopus 로고    scopus 로고
    • Anticardiolipin and anti-beta2GPI antibodies in a large series of European patients with systemic lupus erythematosus. Prevalence and clinical associations. European Concerted Action on the Immunogenetics of SLE
    • Sebastiani GD, Galeazzi M, Tincani A, et al. Anticardiolipin and anti-beta2GPI antibodies in a large series of European patients with systemic lupus erythematosus. Prevalence and clinical associations. European Concerted Action on the Immunogenetics of SLE. Scand J Rheumatol 1999;28:344.
    • (1999) Scand J Rheumatol , vol.28 , pp. 344
    • Sebastiani, G.D.1    Galeazzi, M.2    Tincani, A.3
  • 267
    • 0141958839 scopus 로고    scopus 로고
    • Anti-β2-glycoprotein I, antiprothrombin antibodies and the risk of thrombosis in the antiphospholipid syndrome
    • Galli M, Luciani D, Bertolini G, et al. Anti-β2-glycoprotein I, antiprothrombin antibodies and the risk of thrombosis in the antiphospholipid syndrome. Blood 2003;102:2717.
    • (2003) Blood , vol.102 , pp. 2717
    • Galli, M.1    Luciani, D.2    Bertolini, G.3
  • 268
    • 0033194831 scopus 로고    scopus 로고
    • Anti-beta2-glycoprotein I antibodies in women with recurrent spontaneous abortion, unexplained fetal death, and antiphospholipid syndrome
    • Lee RM, Emlen W, Scott JR, et al. Anti-beta2-glycoprotein I antibodies in women with recurrent spontaneous abortion, unexplained fetal death, and antiphospholipid syndrome. Am J Obstet Gynecol 1999;181:642.
    • (1999) Am J Obstet Gynecol , vol.181 , pp. 642
    • Lee, R.M.1    Emlen, W.2    Scott, J.R.3
  • 269
    • 0033068141 scopus 로고    scopus 로고
    • Association of antibodies to beta2-glycoprotein 1 with pregnancy loss and pregnancy-induced hypertension: A prospective study in low-risk pregnancy
    • Lynch A, Byers T, Emlen W, et al. Association of antibodies to beta2-glycoprotein 1 with pregnancy loss and pregnancy-induced hypertension:a prospective study in low-risk pregnancy. Obstet Gynecol 1999;93:193.
    • (1999) Obstet Gynecol , vol.93 , pp. 193
    • Lynch, A.1    Byers, T.2    Emlen, W.3
  • 270
    • 0033622167 scopus 로고    scopus 로고
    • beta2-glycoprotein 1 as a marker of antiphospholipid syndrome in women with recurrent pregnancy loss
    • Franklin RD, Hollier N, Kutteh. beta2-Glycoprotein 1 as a marker of antiphospholipid syndrome in women with recurrent pregnancy loss. Fertil Steril 2000;73:531.
    • (2000) Fertil Steril , vol.73 , pp. 531
    • Franklin, R.D.1    Hollier, N.2    Kutteh3
  • 271
    • 0036267064 scopus 로고    scopus 로고
    • Value of autoantibodies to beta(2)-glycoprotein 1 in the diagnosis of antiphospholipid syndrome
    • Audrain MA, El-Kouri D, Hamidou MA, et al. Value of autoantibodies to beta(2)-glycoprotein 1 in the diagnosis of antiphospholipid syndrome. Rheumatology (Oxford) 2002;41:550.
    • (2002) Rheumatology (Oxford) , vol.41 , pp. 550
    • Audrain, M.A.1    El-Kouri, D.2    Hamidou, M.A.3
  • 272
    • 0033833598 scopus 로고    scopus 로고
    • Should we include anti-prothrombin antibodies in the screening for the antiphospholipid syndrome?
    • Galli M. Should we include anti-prothrombin antibodies in the screening for the antiphospholipid syndrome? J Autoimmun 2000;15:101.
    • (2000) J Autoimmun , vol.15 , pp. 101
    • Galli, M.1
  • 273
    • 0020604029 scopus 로고
    • A mechanism for the hypoprothrombinemia of the acquired hypoprothrombinemia-lupus anticoagulant syndrome
    • Bajaj SP, Rapaport SI, Fierer DS, et al. A mechanism for the hypoprothrombinemia of the acquired hypoprothrombinemia-lupus anticoagulant syndrome. Blood 1983;61:684.
    • (1983) Blood , vol.61 , pp. 684
    • Bajaj, S.P.1    Rapaport, S.I.2    Fierer, D.S.3
  • 274
    • 0021224002 scopus 로고
    • Abnormal prothrombin crossed immunoelectrophoresis in patients with lupus inhibitors
    • Edson JR, Vogt JM, Hasegawa DK. Abnormal prothrombin crossed immunoelectrophoresis in patients with lupus inhibitors. Blood 1984;64:807.
    • (1984) Blood , vol.64 , pp. 807
    • Edson, J.R.1    Vogt, J.M.2    Hasegawa, D.K.3
  • 275
    • 0023772539 scopus 로고
    • Anti-prothrombin antibodies and the lupus anticoagulant
    • Fleck RA, Rapaport SI, Rao LV. Anti-prothrombin antibodies and the lupus anticoagulant. Blood 1988;72:512.
    • (1988) Blood , vol.72 , pp. 512
    • Fleck, R.A.1    Rapaport, S.I.2    Rao, L.V.3
  • 276
    • 0028827568 scopus 로고
    • Development of an ELISA for autoantibodies to prothrombin showing their prevalence in patients with lupus anticoagulants
    • Arvieux J, Darnige L, Caron C, et al. Development of an ELISA for autoantibodies to prothrombin showing their prevalence in patients with lupus anticoagulants. Thromb Haemost 1995;74:1120.
    • (1995) Thromb Haemost , vol.74 , pp. 1120
    • Arvieux, J.1    Darnige, L.2    Caron, C.3
  • 277
    • 16744363823 scopus 로고    scopus 로고
    • Antiprothrombin and antiannexin V antibodies imply risk of thrombosis in patients with systemic autoimmune diseases
    • Lakos G, Kiss E, Regeczy N, et al. Antiprothrombin and antiannexin V antibodies imply risk of thrombosis in patients with systemic autoimmune diseases. J Rheumatol 2000;27:924.
    • (2000) J Rheumatol , vol.27 , pp. 924
    • Lakos, G.1    Kiss, E.2    Regeczy, N.3
  • 278
    • 0030199628 scopus 로고    scopus 로고
    • Antibodies to phospholipid-binding plasma proteins and occurrence of thrombosis in patients with systemic lupus erythematosus
    • Puurunen M, Vaarala O, Julkunen H, et al. Antibodies to phospholipid-binding plasma proteins and occurrence of thrombosis in patients with systemic lupus erythematosus. Clin Immunol Immunopathol 1996;80:16.
    • (1996) Clin Immunol Immunopathol , vol.80 , pp. 16
    • Puurunen, M.1    Vaarala, O.2    Julkunen, H.3
  • 279
    • 0031757439 scopus 로고    scopus 로고
    • Anti-prothrombin but not "pure" anti-cardiolipin antibodies are associated with the clinical features of the antiphospholipid antibody syndrome
    • Sorice M, Pittoni V, Circella A, et al. Anti-prothrombin but not "pure" anti-cardiolipin antibodies are associated with the clinical features of the antiphospholipid antibody syndrome. Thromb Haemost 1998;80:713.
    • (1998) Thromb Haemost , vol.80 , pp. 713
    • Sorice, M.1    Pittoni, V.2    Circella, A.3
  • 280
    • 0031876557 scopus 로고    scopus 로고
    • Autoantibodies to human prothrombin and clinical manifestations in 207 patients with systemic lupus erythematosus
    • Bertolaccini ML, Atsumi T, Khamashta MA, et al. Autoantibodies to human prothrombin and clinical manifestations in 207 patients with systemic lupus erythematosus. J Rheumatol 1998;25:1104.
    • (1998) J Rheumatol , vol.25 , pp. 1104
    • Bertolaccini, M.L.1    Atsumi, T.2    Khamashta, M.A.3
  • 281
    • 18844471340 scopus 로고    scopus 로고
    • Prevalence and clinical significance of antiprothrombin antibodies in patients with systemic lupus erythematosus or with primary antiphospholipid syndrome
    • Munoz-Rodriguez FJ, Reverter JC, Font J, et al. Prevalence and clinical significance of antiprothrombin antibodies in patients with systemic lupus erythematosus or with primary antiphospholipid syndrome. Haematologica 2000;85:632.
    • (2000) Haematologica , vol.85 , pp. 632
    • Munoz-Rodriguez, F.J.1    Reverter, J.C.2    Font, J.3
  • 282
    • 0034791684 scopus 로고    scopus 로고
    • Anti-prothrombin antibodies combined with lupus anti-coagulant activity is an essential risk factor for venous thromboembolism in patients with systemic lupus erythematosus
    • Nojima J, Kuratsune H, Suehisa E, et al. Anti-prothrombin antibodies combined with lupus anti-coagulant activity is an essential risk factor for venous thromboembolism in patients with systemic lupus erythematosus. Br J Haematol 2001;114:647.
    • (2001) Br J Haematol , vol.114 , pp. 647
    • Nojima, J.1    Kuratsune, H.2    Suehisa, E.3
  • 283
    • 0029896410 scopus 로고    scopus 로고
    • Autoantibodies to phospholipid-binding plasma proteins in patients with thrombosis and phospholipid-reactive antibodies
    • Pengo V, Biasiolo A, Brocco T, et al. Autoantibodies to phospholipid-binding plasma proteins in patients with thrombosis and phospholipid-reactive antibodies. Thromb Haemost 1996;75:721.
    • (1996) Thromb Haemost , vol.75 , pp. 721
    • Pengo, V.1    Biasiolo, A.2    Brocco, T.3
  • 284
    • 0030743008 scopus 로고    scopus 로고
    • Relationship of lupus anticoagulant, anticardiolipin, anti-beta2-GPI and antiprothrombin autoantibodies with history of thrombosis in patients with the clinical suspicion of APA-syndrome
    • D'Angelo A, Safa O, Crippa L, et al. Relationship of lupus anticoagulant, anticardiolipin, anti-beta2-GPI and antiprothrombin autoantibodies with history of thrombosis in patients with the clinical suspicion of APA-syndrome. Thromb Haemost 1997;78:967.
    • (1997) Thromb Haemost , vol.78 , pp. 967
    • D'Angelo, A.1    Safa, O.2    Crippa, L.3
  • 285
    • 0030608864 scopus 로고    scopus 로고
    • Relationship of anti beta2-glycoprotein I and anti prothrombin antibodies to thrombosis and pregnancy loss in patients with antiphospholipid antibodies
    • Forastiero RR, Martinuzzo ME, Cerrato GS, et al. Relationship of anti beta2-glycoprotein I and anti prothrombin antibodies to thrombosis and pregnancy loss in patients with antiphospholipid antibodies. Thromb Haemost 1997;78:1008.
    • (1997) Thromb Haemost , vol.78 , pp. 1008
    • Forastiero, R.R.1    Martinuzzo, M.E.2    Cerrato, G.S.3
  • 286
    • 0030937274 scopus 로고    scopus 로고
    • Different anticoagulant and immunological properties of anti-prothrombin antibodies in patients with antiphospholipid antibodies
    • Galli M, Beretta G, Daldossi M, et al. Different anticoagulant and immunological properties of anti-prothrombin antibodies in patients with antiphospholipid antibodies. Thromb Haemost 1997;77:486.
    • (1997) Thromb Haemost , vol.77 , pp. 486
    • Galli, M.1    Beretta, G.2    Daldossi, M.3
  • 287
    • 0033711669 scopus 로고    scopus 로고
    • Association of autoantibodies against the phosphatidylserine-prothrombin complex with manifestations of the antiphospholipid syndrome and with the presence of lupus anticoagulant
    • Atsumi T, Ieko M, Bertolaccini ML, et al. Association of autoantibodies against the phosphatidylserine-prothrombin complex with manifestations of the antiphospholipid syndrome and with the presence of lupus anticoagulant. Arthritis Rheum 2000;43:1982.
    • (2000) Arthritis Rheum , vol.43 , pp. 1982
    • Atsumi, T.1    Ieko, M.2    Bertolaccini, M.L.3
  • 288
    • 0037386632 scopus 로고    scopus 로고
    • Specificities, properties, and clinical significance of antiprothrombin antibodies
    • Amengual O, Atsumi T, Koike T. Specificities, properties, and clinical significance of antiprothrombin antibodies. Arthritis Rheum 2003;48:886.
    • (2003) Arthritis Rheum , vol.48 , pp. 886
    • Amengual, O.1    Atsumi, T.2    Koike, T.3
  • 289
    • 0029129109 scopus 로고
    • Antibody to annexin V has anti-phospholipid and lupus anticoagulant properties
    • Nakamura N, Kuragaki C, Shidara Y, et al. Antibody to annexin V has anti-phospholipid and lupus anticoagulant properties. Am J Hematol 1995;49:347.
    • (1995) Am J Hematol , vol.49 , pp. 347
    • Nakamura, N.1    Kuragaki, C.2    Shidara, Y.3
  • 290
    • 0032794523 scopus 로고    scopus 로고
    • Detection of antiannexin IV and V antibodies in patients with antiphospholipid syndrome and systemic lupus erythematosus
    • Satoh A, Suzuki K, Takayama E, et al. Detection of antiannexin IV and V antibodies in patients with antiphospholipid syndrome and systemic lupus erythematosus. J Rheumatol 1999;26:1715.
    • (1999) J Rheumatol , vol.26 , pp. 1715
    • Satoh, A.1    Suzuki, K.2    Takayama, E.3
  • 291
    • 0034424908 scopus 로고    scopus 로고
    • Elevated anti-annexin V antibody levels in antiphospholipid syndrome and their involvement in antiphospholipid antibody specificities
    • Ogawa H, Zhao D, Dlott JS, et al. Elevated anti-annexin V antibody levels in antiphospholipid syndrome and their involvement in antiphospholipid antibody specificities. Am J Clin Pathol 2000;114:619.
    • (2000) Am J Clin Pathol , vol.114 , pp. 619
    • Ogawa, H.1    Zhao, D.2    Dlott, J.S.3
  • 292
    • 0030891181 scopus 로고    scopus 로고
    • Clinical significance of anti-annexin V antibodies in patients with systemic lupus erythematosus
    • Kaburaki J, Kuwana M, Yamamoto M, et al. Clinical significance of anti-annexin V antibodies in patients with systemic lupus erythematosus. Am J Hematol 1997; 54:209.
    • (1997) Am J Hematol , vol.54 , pp. 209
    • Kaburaki, J.1    Kuwana, M.2    Yamamoto, M.3
  • 294
    • 0026333959 scopus 로고
    • Role of oxidized low density lipoprotein in atherogenesis
    • Witztum JL, Steinberg D. Role of oxidized low density lipoprotein in atherogenesis. J Clin Invest 1991;88:1785.
    • (1991) J Clin Invest , vol.88 , pp. 1785
    • Witztum, J.L.1    Steinberg, D.2
  • 295
    • 0028881323 scopus 로고
    • Autoantibodies against oxidized low density lipoproteins (oxLDL): Characterization of antibody isotype, subclass; affinity and effect on the macrophage uptake of oxLDL
    • Wu R, Lefvert AK. Autoantibodies against oxidized low density lipoproteins (oxLDL): Characterization of antibody isotype, subclass; affinity and effect on the macrophage uptake of oxLDL. Clin Exp Immunol 1995;102:174.
    • (1995) Clin Exp Immunol , vol.102 , pp. 174
    • Wu, R.1    Lefvert, A.K.2
  • 296
    • 0027971549 scopus 로고
    • Antibody against oxidized low-density lipoprotein predicting myocardial infarction
    • Puurunen M, Manttari M, Manninen V, et al. Antibody against oxidized low-density lipoprotein predicting myocardial infarction. Arch Intern Med 1994;154:2605.
    • (1994) Arch Intern Med , vol.154 , pp. 2605
    • Puurunen, M.1    Manttari, M.2    Manninen, V.3
  • 297
    • 0034652224 scopus 로고    scopus 로고
    • Cardiolipin is a normal component of human plasma lipoproteins
    • Deguchi H, Fernandez JA, Hackeng TM, et al. Cardiolipin is a normal component of human plasma lipoproteins. Proc Natl Acad Sci USA 2000;97:1743.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 1743
    • Deguchi, H.1    Fernandez, J.A.2    Hackeng, T.M.3
  • 298
    • 0035916304 scopus 로고    scopus 로고
    • Anticardiolipin antibodies from patients with the antiphospholipid antibody syndrome recognize epitopes in both beta(2)-glycoprotein 1 and oxidized low-density lipoprotein
    • Horkko S, Olee T, Mo L, et al. Anticardiolipin antibodies from patients with the antiphospholipid antibody syndrome recognize epitopes in both beta(2)-glycoprotein 1 and oxidized low-density lipoprotein. Circulation 2001;103:941.
    • (2001) Circulation , vol.103 , pp. 941
    • Horkko, S.1    Olee, T.2    Mo, L.3
  • 299
    • 0030867292 scopus 로고    scopus 로고
    • Autoantibodies against oxidized low-density lipoprotein in antiphospholipid syndrome
    • Amengual O, Atsumi T, Khamashta MA, et al. Autoantibodies against oxidized low-density lipoprotein in antiphospholipid syndrome. Br J Rheumatol 1997; 36:964.
    • (1997) Br J Rheumatol , vol.36 , pp. 964
    • Amengual, O.1    Atsumi, T.2    Khamashta, M.A.3
  • 300
    • 0035736459 scopus 로고    scopus 로고
    • Oxidized low-density lipoprotein and autoimmune antibodies in patients with antiphospholipid syndrome with a history of thrombosis
    • Zhao D, Ogawa H, Wang X, et al. Oxidized low-density lipoprotein and autoimmune antibodies in patients with antiphospholipid syndrome with a history of thrombosis. Am J Clin Pathol 2001;116:760.
    • (2001) Am J Clin Pathol , vol.116 , pp. 760
    • Zhao, D.1    Ogawa, H.2    Wang, X.3
  • 301
    • 0034993766 scopus 로고    scopus 로고
    • Anti-oxidized low-density-lipoprotein (OxLDL) antibodies in systemic lupus erythematosus with and without antiphospholipid syndrome
    • Hayem G, Nicaise-Roland P, Palazzo E, et al. Anti-oxidized low-density-lipoprotein (OxLDL) antibodies in systemic lupus erythematosus with and without antiphospholipid syndrome. Lupus 2001;10:346.
    • (2001) Lupus , vol.10 , pp. 346
    • Hayem, G.1    Nicaise-Roland, P.2    Palazzo, E.3
  • 302
    • 0031856327 scopus 로고    scopus 로고
    • Arterial disease in lupus and secondary antiphospholipid syndrome: Association with anti-beta2-glycoprotein I antibodies but not with antibodies against oxidized low-density lipoprotein
    • Romero FI, Amengual O, Atsumi T, et al. Arterial disease in lupus and secondary antiphospholipid syndrome: Association with anti-beta2-glycoprotein I antibodies but not with antibodies against oxidized low-density lipoprotein. Br J Rheumatol 1998;37:883.
    • (1998) Br J Rheumatol , vol.37 , pp. 883
    • Romero, F.I.1    Amengual, O.2    Atsumi, T.3
  • 303
    • 0026355289 scopus 로고
    • Antiendothelial cell antibodies in patients with the antiphospholipid syndrome
    • Cervera R, Khamashta MA, Font J, et al. Antiendothelial cell antibodies in patients with the antiphospholipid syndrome. Autoimmunity 1991;11:1.
    • (1991) Autoimmunity , vol.11 , pp. 1
    • Cervera, R.1    Khamashta, M.A.2    Font, J.3
  • 304
    • 0023790693 scopus 로고
    • Relationship between anti-cardiolipin and anti-endothelial cell antibodies in systemic lupus erythematosus
    • Vismara A, Meroni PL, Tincani A, et al. Relationship between anti-cardiolipin and anti-endothelial cell antibodies in systemic lupus erythematosus. Clin Exp Immunol 1988;74:247.
    • (1988) Clin Exp Immunol , vol.74 , pp. 247
    • Vismara, A.1    Meroni, P.L.2    Tincani, A.3
  • 306
    • 0026354068 scopus 로고
    • Detection of endothelial cell-reactive immunoglobulin in patients with anti-phospholipid antibodies
    • McCrae KR, DeMichele A, Samuels P, et al. Detection of endothelial cell-reactive immunoglobulin in patients with anti-phospholipid antibodies. Br J Haematol 1991;79:595.
    • (1991) Br J Haematol , vol.79 , pp. 595
    • McCrae, K.R.1    DeMichele, A.2    Samuels, P.3
  • 307
    • 0035507820 scopus 로고    scopus 로고
    • Certain autoantibodies to phosphatidylethanolamine (aPE) recognize factor XI and prekallikrein independently or in addition to the kininogens
    • Sugi T, McIntyre JA. Certain autoantibodies to phosphatidylethanolamine (aPE) recognize factor XI and prekallikrein independently or in addition to the kininogens. J Autoimmun 2001;17:207.
    • (2001) J Autoimmun , vol.17 , pp. 207
    • Sugi, T.1    McIntyre, J.A.2
  • 308
    • 0036121572 scopus 로고    scopus 로고
    • Antibodies to factor XII are distinct from antibodies to prothrombin in patients with the anti-phospholipid syndrome
    • Jone DW, Nicholls PJ, Donohoe S, et al. Antibodies to factor XII are distinct from antibodies to prothrombin in patients with the anti-phospholipid syndrome. Thromb Haemost 2002;87:426.
    • (2002) Thromb Haemost , vol.87 , pp. 426
    • Jone, D.W.1    Nicholls, P.J.2    Donohoe, S.3
  • 309
    • 0029829790 scopus 로고    scopus 로고
    • Non beta 2-glycoprotein I cofactors for antiphospholipid antibodies
    • Galli M. Non beta 2-glycoprotein I cofactors for antiphospholipid antibodies. Lupus 1996;5:388.
    • (1996) Lupus , vol.5 , pp. 388
    • Galli, M.1
  • 310
    • 0027956546 scopus 로고
    • Association of antimitochondrial antibodies type 5 and anti-beta 2 glycoprotein I antibodies in the antiphospholipid syndrome
    • Laperche S, Abuaf N, Meyer O, et al. Association of antimitochondrial antibodies type 5 and anti-beta 2 glycoprotein I antibodies in the antiphospholipid syndrome. J Rheumatol 1994;21:1678.
    • (1994) J Rheumatol , vol.21 , pp. 1678
    • Laperche, S.1    Abuaf, N.2    Meyer, O.3
  • 311
    • 0033946660 scopus 로고    scopus 로고
    • Clinical importance of antibodies against platelet activating factor in antiphospholipid syndrome manifestations
    • Tektonidou MG, Petrovas CA, Ioannidis JP, et al. Clinical importance of antibodies against platelet activating factor in antiphospholipid syndrome manifestations. Eur J Clin Invest 2000;30:646.
    • (2000) Eur J Clin Invest , vol.30 , pp. 646
    • Tektonidou, M.G.1    Petrovas, C.A.2    Ioannidis, J.P.3
  • 312
    • 0034030512 scopus 로고    scopus 로고
    • Antibodies to tissue-type plasminogen activator in plasma from patients with primary antiphospholipid syndrome
    • Cugno M, Dominguez M, Cabibbe M, et al. Antibodies to tissue-type plasminogen activator in plasma from patients with primary antiphospholipid syndrome. Br J Haematol 2000;108:871.
    • (2000) Br J Haematol , vol.108 , pp. 871
    • Cugno, M.1    Dominguez, M.2    Cabibbe, M.3
  • 313
    • 0035164974 scopus 로고    scopus 로고
    • Some patients with antiphospholipid syndrome express hitherto undescribed antibodies to cardiolipin-binding proteins
    • Rampazzo P, Biasiolo A, Garin J, et al. Some patients with antiphospholipid syndrome express hitherto undescribed antibodies to cardiolipin-binding proteins. Thromb Haemost 2001;85:57.
    • (2001) Thromb Haemost , vol.85 , pp. 57
    • Rampazzo, P.1    Biasiolo, A.2    Garin, J.3
  • 314
    • 0037327770 scopus 로고    scopus 로고
    • Factor VII/VIIa: A new antigen in the anti-phospholipid antibody syndrome
    • Bidot CJ, Jy W, Horstman LL, Huisheng H, et al. Factor VII/VIIa: A new antigen in the anti-phospholipid antibody syndrome. Br J Haematol 2003;120:618.
    • (2003) Br J Haematol , vol.120 , pp. 618
    • Bidot, C.J.1    Jy, W.2    Horstman, L.L.3    Huisheng, H.4
  • 315
    • 0033510890 scopus 로고    scopus 로고
    • Autoantibodies against malondialdehyde-modified lipoprotein(a) in antiphospholipid syndrome
    • Romero FI, Atsumi T, Tinahones FJ, et al. Autoantibodies against malondialdehyde-modified lipoprotein(a) in antiphospholipid syndrome. Arthritis Rheum 1999;42:2606.
    • (1999) Arthritis Rheum , vol.42 , pp. 2606
    • Romero, F.I.1    Atsumi, T.2    Tinahones, F.J.3
  • 316
    • 0029767835 scopus 로고    scopus 로고
    • Advantage of using both anionic and zwitterionic phospholipid antigens for the detection of antiphospholipid antibodies
    • Laroche P, Berard M, Rouquette AM, et al. Advantage of using both anionic and zwitterionic phospholipid antigens for the detection of antiphospholipid antibodies. Am J Clin Pathol 1996;106:549.
    • (1996) Am J Clin Pathol , vol.106 , pp. 549
    • Laroche, P.1    Berard, M.2    Rouquette, A.M.3
  • 317
    • 0031761048 scopus 로고    scopus 로고
    • Multiple antiphospholipid tests do not increase the diagnostic yield in antiphospholipid syndrome
    • Bertolaccini ML, Roch B, Amengual O, et al. Multiple antiphospholipid tests do not increase the diagnostic yield in antiphospholipid syndrome. Br J Rheumatol 1998;37:1229.
    • (1998) Br J Rheumatol , vol.37 , pp. 1229
    • Bertolaccini, M.L.1    Roch, B.2    Amengual, O.3
  • 319
    • 0029783366 scopus 로고    scopus 로고
    • Antiphosphatidylethanolamine antibodies as the only antiphospholipid antibodies. I. Association with thrombosis and vascular cutaneous diseases
    • Berard M, Chantome R, Marcelli A, et al. Antiphosphatidylethanolamine antibodies as the only antiphospholipid antibodies. I. Association with thrombosis and vascular cutaneous diseases. J Rheumatol 1996;23:1369.
    • (1996) J Rheumatol , vol.23 , pp. 1369
    • Berard, M.1    Chantome, R.2    Marcelli, A.3
  • 320
    • 0027248262 scopus 로고
    • Antiphosphatidylethanolamine antibodies in systemic lupus erythematosus
    • Karmochkine M, Berard M, Piette JC, et al. Antiphosphatidylethanolamine antibodies in systemic lupus erythematosus. Lupus 1993;2:157.
    • (1993) Lupus , vol.2 , pp. 157
    • Karmochkine, M.1    Berard, M.2    Piette, J.C.3
  • 321
    • 0027744020 scopus 로고
    • Prevalence and clinical significance of antiphospholipid antibodies to noncardiolipin antigens in systemic lupus erythematosus
    • Toschi V, Motta A, Castelli C, et al. Prevalence and clinical significance of antiphospholipid antibodies to noncardiolipin antigens in systemic lupus erythematosus. Haemostasis 1993;23:275.
    • (1993) Haemostasis , vol.23 , pp. 275
    • Toschi, V.1    Motta, A.2    Castelli, C.3
  • 322
    • 0031714987 scopus 로고    scopus 로고
    • High prevalence of antiphosphatidylinositol antibodies in young patients with cerebral ischemia of undetermined cause
    • Toschi V, Motta A, Castelli C, et al. High prevalence of antiphosphatidylinositol antibodies in young patients with cerebral ischemia of undetermined cause. Stroke 1998;29:1759.
    • (1998) Stroke , vol.29 , pp. 1759
    • Toschi, V.1    Motta, A.2    Castelli, C.3
  • 323
    • 0025213534 scopus 로고
    • Antiphosphatidylinositol antibodies as markers of the antiphospholipid syndrome
    • Falcon CR, Hoffer AM, Carreras LO. Antiphosphatidylinositol antibodies as markers of the antiphospholipid syndrome. Thromb Haemost 1990;63:321.
    • (1990) Thromb Haemost , vol.63 , pp. 321
    • Falcon, C.R.1    Hoffer, A.M.2    Carreras, L.O.3
  • 324
    • 15144349600 scopus 로고    scopus 로고
    • Isotype distribution and clinical significance of antibodies to cardiolipin, phosphatidic acid, phosphatidylinositol and phosphatidylserine in systemic lupus erythematosus: Prospective analysis of a series of 92 patients
    • Lopez-Soto A, Cervera R, Font J, et al. Isotype distribution and clinical significance of antibodies to cardiolipin, phosphatidic acid, phosphatidylinositol and phosphatidylserine in systemic lupus erythematosus: Prospective analysis of a series of 92 patients. Clin Exp Rheumatol 1997;15:143.
    • (1997) Clin Exp Rheumatol , vol.15 , pp. 143
    • Lopez-Soto, A.1    Cervera, R.2    Font, J.3
  • 325
    • 0023883055 scopus 로고
    • Studies of IgG, IgM and IgA antiphospholipid antibody isotypes in systemic lupus erythematosus
    • Weidmann CE, Wallace DJ, Peter JB, et al. Studies of IgG, IgM and IgA antiphospholipid antibody isotypes in systemic lupus erythematosus. J Rheumatol 1988;15:74.
    • (1988) J Rheumatol , vol.15 , pp. 74
    • Weidmann, C.E.1    Wallace, D.J.2    Peter, J.B.3
  • 326
    • 0031128310 scopus 로고    scopus 로고
    • Antiphospholipid antibodies other than lupus anticoagulant and anticardiolipin antibodies in women with recurrent pregnancy loss, fertile controls, and antiphospholipid syndrome
    • Branch DW, Silver R, Pierangeli S, et al. Antiphospholipid antibodies other than lupus anticoagulant and anticardiolipin antibodies in women with recurrent pregnancy loss, fertile controls, and antiphospholipid syndrome. Obstet Gynecol 1997;89:549.
    • (1997) Obstet Gynecol , vol.89 , pp. 549
    • Branch, D.W.1    Silver, R.2    Pierangeli, S.3
  • 327
    • 0022178199 scopus 로고
    • Measurement of anti-cardiolipin antibodies by an enzyme-linked immunosorbentassay (ELISA): Standardization and quantitation of results
    • Loizou S, McCrea JD, Rudge AC, et al. Measurement of anti-cardiolipin antibodies by an enzyme-linked immunosorbentassay (ELISA): Standardization and quantitation of results. Clin Exp Immunol 1985;62:738.
    • (1985) Clin Exp Immunol , vol.62 , pp. 738
    • Loizou, S.1    McCrea, J.D.2    Rudge, A.C.3
  • 328
    • 0027930963 scopus 로고
    • Prevalence, follow-up and clinical significance of the anticardiolipin antibodies in normal subjects
    • Vila P, Hernandez MC, Lopez-Fernandez MF, et al. Prevalence, follow-up and clinical significance of the anticardiolipin antibodies in normal subjects. Thromb Haemost 1994;72:209.
    • (1994) Thromb Haemost , vol.72 , pp. 209
    • Vila, P.1    Hernandez, M.C.2    Lopez-Fernandez, M.F.3
  • 329
    • 0034872049 scopus 로고    scopus 로고
    • Classification criteria for antiphospholipid syndrome
    • Wilson WA. Classification criteria for antiphospholipid syndrome. Rheum Dis Clin North Am 2001;27:499.
    • (2001) Rheum Dis Clin North Am , vol.27 , pp. 499
    • Wilson, W.A.1
  • 330
  • 331
    • 0034924140 scopus 로고    scopus 로고
    • International classification criteria for antiphospholipid syndrome: Synopsis of a post-conference workshop held at the Ninth International (Tours) aPL Symposium
    • Wilson WA, Gharavi AE, Piette JC. International classification criteria for antiphospholipid syndrome: Synopsis of a post-conference workshop held at the Ninth International (Tours) aPL Symposium. Lupus 2001;10:457.
    • (2001) Lupus , vol.10 , pp. 457
    • Wilson, W.A.1    Gharavi, A.E.2    Piette, J.C.3
  • 332
    • 0027131931 scopus 로고
    • Exclusion criteria for primary antiphospholipid syndrome
    • Piette JC, Wechsler B, Frances C, et al. Exclusion criteria for primary antiphospholipid syndrome. J Rheumatol 1993;20:1802.
    • (1993) J Rheumatol , vol.20 , pp. 1802
    • Piette, J.C.1    Wechsler, B.2    Frances, C.3
  • 333
    • 0026585838 scopus 로고
    • Repeated fetal losses associated with antiphospholipid antibodies: A collaborative randomized trial comparing prednisone with low-dose heparin treatment
    • Cowchock FS, Reece EA, Balaban D, et al. Repeated fetal losses associated with antiphospholipid antibodies: A collaborative randomized trial comparing prednisone with low-dose heparin treatment. Am J Obstet Gynecol 1992;166:1318.
    • (1992) Am J Obstet Gynecol , vol.166 , pp. 1318
    • Cowchock, F.S.1    Reece, E.A.2    Balaban, D.3
  • 334
    • 0027715350 scopus 로고
    • Low-dose aspirin for prevention of pregnancy losses in women with primary antiphospholipid syndrome
    • Balasch J, Carmona F, Lopez-Soto A, et al. Low-dose aspirin for prevention of pregnancy losses in women with primary antiphospholipid syndrome. Hum Reprod 1993;8:2234.
    • (1993) Hum Reprod , vol.8 , pp. 2234
    • Balasch, J.1    Carmona, F.2    Lopez-Soto, A.3
  • 335
    • 0036711316 scopus 로고    scopus 로고
    • Antiphospholipid syndrome in pregnancy: A randomized, controlled trial of treatment
    • Farquharson RG, Quenby S, Greaves M. Antiphospholipid syndrome in pregnancy: A randomized, controlled trial of treatment. Obstet Gynecol 2002;100:408.
    • (2002) Obstet Gynecol , vol.100 , pp. 408
    • Farquharson, R.G.1    Quenby, S.2    Greaves, M.3
  • 336
    • 0034971358 scopus 로고    scopus 로고
    • High thrombosis rate after fetal loss in antiphospholipid syndrome: Effective prophylaxis with aspirin
    • Erkan D, Merrill JT, Yazici Y, et al. High thrombosis rate after fetal loss in antiphospholipid syndrome: Effective prophylaxis with aspirin. Arthritis Rheum 2001;44:1466.
    • (2001) Arthritis Rheum , vol.44 , pp. 1466
    • Erkan, D.1    Merrill, J.T.2    Yazici, Y.3
  • 337
    • 0034631861 scopus 로고    scopus 로고
    • Prophylactic antithrombotic therapy for patients with systemic lupus erythematosus with or without antiphospholipid antibodies: Do the benefits outweigh the risks? A decision analysis
    • Wahl DG, Bounameaux H, de Moerloose P, et al. Prophylactic antithrombotic therapy for patients with systemic lupus erythematosus with or without antiphospholipid antibodies: Do the benefits outweigh the risks? A decision analysis. Arch Intern Med 2000;160:2042.
    • (2000) Arch Intern Med , vol.160 , pp. 2042
    • Wahl, D.G.1    Bounameaux, H.2    De Moerloose, P.3
  • 338
    • 0031910205 scopus 로고    scopus 로고
    • Hydroxychloroquine: Past, present, future
    • Petri M. Hydroxychloroquine: Past, present, future. Lupus 1998;7:65.
    • (1998) Lupus , vol.7 , pp. 65
    • Petri, M.1
  • 339
    • 0034865787 scopus 로고    scopus 로고
    • Management of thrombosis in antiphospholipid antibody syndrome
    • Petri M. Management of thrombosis in antiphospholipid antibody syndrome. Rheum Dis Clin North Am 2001; 27:633.
    • (2001) Rheum Dis Clin North Am , vol.27 , pp. 633
    • Petri, M.1
  • 340
    • 0002018090 scopus 로고    scopus 로고
    • Antiphospholipid antibody syndrome
    • Ruddy S, Harris ED, Sledge CB, eds. Philadelphia: W.B. Saunders Company
    • Lockshin MD. Antiphospholipid antibody syndrome. In: Ruddy S, Harris ED, Sledge CB, eds. Kelly's Textbook of Rheumatology. Philadelphia: W.B. Saunders Company, 2001;1145.
    • (2001) Kelly's Textbook of Rheumatology , pp. 1145
    • Lockshin, M.D.1
  • 341
    • 0034115413 scopus 로고    scopus 로고
    • The antiphospholipid syndrome: Immunologic and clinical aspects. Clinical spectrum and treatment
    • Myones BL, McCurdy D. The antiphospholipid syndrome: Immunologic and clinical aspects. Clinical spectrum and treatment. J Rheumatol 2000;27 Suppl 58:20.
    • (2000) J Rheumatol , vol.27 , Issue.SUPPL. 58 , pp. 20
    • Myones, B.L.1    McCurdy, D.2
  • 342
    • 0039466611 scopus 로고    scopus 로고
    • Treatment of hereditary and acquired thrombophilic disorders
    • Baker WF Jr, Bick RL. Treatment of hereditary and acquired thrombophilic disorders. Semin Thromb Hemost 1999;25:387.
    • (1999) Semin Thromb Hemost , vol.25 , pp. 387
    • Baker Jr., W.F.1    Bick, R.L.2
  • 343
    • 0025955648 scopus 로고
    • Successful thrombolytic therapy for acute myocardial infarction in a patient with the antiphospholipid antibody syndrome
    • Harpaz D, Glikson M, Sidi Y, et al. Successful thrombolytic therapy for acute myocardial infarction in a patient with the antiphospholipid antibody syndrome. Am Heart J 1991;122:1492.
    • (1991) Am Heart J , vol.122 , pp. 1492
    • Harpaz, D.1    Glikson, M.2    Sidi, Y.3
  • 344
    • 0029889016 scopus 로고    scopus 로고
    • Successful treatment of acute myocardial infarction by thrombolytic therapy in a patient with primary antiphospholipid antibody syndrome
    • Ho YL, Chen MF, Wu CC, et al. Successful treatment of acute myocardial infarction by thrombolytic therapy in a patient with primary antiphospholipid antibody syndrome. Cardiology 1996;87:354.
    • (1996) Cardiology , vol.87 , pp. 354
    • Ho, Y.L.1    Chen, M.F.2    Wu, C.C.3
  • 345
    • 0032465371 scopus 로고    scopus 로고
    • Successful coronary stent implantation in a patient with primary antiphospholipid syndrome
    • Jankowski M, Dudek D, Dubiel JS, et al. Successful coronary stent implantation in a patient with primary antiphospholipid syndrome. Blood Coagul Fibrinolysis 1998;9:753.
    • (1998) Blood Coagul Fibrinolysis , vol.9 , pp. 753
    • Jankowski, M.1    Dudek, D.2    Dubiel, J.S.3
  • 346
    • 0028908094 scopus 로고
    • The management of thrombosis in the antiphospholipid-antibody syndrome
    • Khamashta MA, Cuadrado MJ, Mujic F, et al. The management of thrombosis in the antiphospholipid-antibody syndrome. N Engl J Med 1995;332:993.
    • (1995) N Engl J Med , vol.332 , pp. 993
    • Khamashta, M.A.1    Cuadrado, M.J.2    Mujic, F.3
  • 347
    • 0033826979 scopus 로고    scopus 로고
    • Do we know which patients with the antiphospholipid syndrome should receive long-term high dose anti-coagulation?
    • Derksen RHWM, de Groot PG. Do we know which patients with the antiphospholipid syndrome should receive long-term high dose anti-coagulation? J Autoimmun 2000;15:255.
    • (2000) J Autoimmun , vol.15 , pp. 255
    • Derksen, R.H.W.M.1    De Groot, P.G.2
  • 348
    • 0038038390 scopus 로고    scopus 로고
    • Prophylaxis of the antiphospholipid syndrome: A consensus report
    • Alarcon-Segovia D, Boffa MC, Branch W, et al. Prophylaxis of the antiphospholipid syndrome: A consensus report. Lupus 2003;12:499.
    • (2003) Lupus , vol.12 , pp. 499
    • Alarcon-Segovia, D.1    Boffa, M.C.2    Branch, W.3
  • 349
    • 0030612094 scopus 로고    scopus 로고
    • Hemorrhagic complications of long-term anticoagulant therapy in seven patients with systemic lupus erythematosus and antiphospholipid syndrome
    • al Sayegh FA, Ensworth S, Huang S, et al. Hemorrhagic complications of long-term anticoagulant therapy in seven patients with systemic lupus erythematosus and antiphospholipid syndrome. J Rheumatol 1997;24:1716.
    • (1997) J Rheumatol , vol.24 , pp. 1716
    • Al Sayegh, F.A.1    Ensworth, S.2    Huang, S.3
  • 350
    • 0027291892 scopus 로고
    • Bleeding complications in oral anticoagulant therapy. An analysis of risk factors
    • van der Meer FJ, Rosendaal FR, Vandenbroucke JP, et al. Bleeding complications in oral anticoagulant therapy. An analysis of risk factors. Arch Intern Med 1993; 153:1557.
    • (1993) Arch Intern Med , vol.153 , pp. 1557
    • Van Der Meer, F.J.1    Rosendaal, F.R.2    Vandenbroucke, J.P.3
  • 351
    • 0032844319 scopus 로고    scopus 로고
    • The effects of low-intensity warfarin on coagulation activation in patients with antiphospholipid antibodies and systemic lupus erythematosus
    • Douketis JD, Crowther MA, Julian JA, et al. The effects of low-intensity warfarin on coagulation activation in patients with antiphospholipid antibodies and systemic lupus erythematosus. Thromb Haemost 1999;82:1028.
    • (1999) Thromb Haemost , vol.82 , pp. 1028
    • Douketis, J.D.1    Crowther, M.A.2    Julian, J.A.3
  • 352
    • 0141791073 scopus 로고    scopus 로고
    • A comparison of two intensities of warfarin for the prevention of recurrent thrombosis in patients with the antiphospholipid antibody syndrome
    • Crowther MA, Ginsberg JS, Julian J, et al. A comparison of two intensities of warfarin for the prevention of recurrent thrombosis in patients with the antiphospholipid antibody syndrome. N Engl J Med 2003;349:1133.
    • (2003) N Engl J Med , vol.349 , pp. 1133
    • Crowther, M.A.1    Ginsberg, J.S.2    Julian, J.3
  • 353
    • 0031203621 scopus 로고    scopus 로고
    • Monitoring warfarin therapy in patients with lupus anticoagulants
    • Moll S, Ortel TL. Monitoring warfarin therapy in patients with lupus anticoagulants. Ann Intern Med 1997; 127:177.
    • (1997) Ann Intern Med , vol.127 , pp. 177
    • Moll, S.1    Ortel, T.L.2
  • 354
    • 0029813875 scopus 로고    scopus 로고
    • Potential failure of the International Normalized Ratio (INR) System in the monitoring of oral anticoagulation in patients with lupus anticoagulants
    • Della Valle P, Crippa L, Safa O, et al. Potential failure of the International Normalized Ratio (INR) System in the monitoring of oral anticoagulation in patients with lupus anticoagulants. Ann Med Interne (Paris) 1996;147 Suppl 1:10.
    • (1996) Ann Med Interne (Paris) , vol.147 , Issue.SUPPL. 1 , pp. 10
    • Della Valle, P.1    Crippa, L.2    Safa, O.3
  • 355
    • 0032755971 scopus 로고    scopus 로고
    • Long-term outpatient dalteparin (fragmin) therapy for arterial and venous thrombosis: Efficacy and safety-a preliminary report
    • Bick RL, Rice J. Long-term outpatient dalteparin (fragmin) therapy for arterial and venous thrombosis: Efficacy and safety-a preliminary report. Clin Appl Thromb Hemost 1999;5 (Suppl 1):S67.
    • (1999) Clin Appl Thromb Hemost , vol.5 , Issue.SUPPL. 1
    • Bick, R.L.1    Rice, J.2
  • 356
    • 0037169563 scopus 로고    scopus 로고
    • Heparin inhibits the binding of beta 2-glycoprotein I to phospholipids and promotes the plasmin-mediated inactivation of this blood protein. Elucidation of the consequences of the two biological events in patients with the anti-phospholipid syndrome
    • Guerin J, Sheng Y, Reddel S, et al. Heparin inhibits the binding of beta 2-glycoprotein I to phospholipids and promotes the plasmin-mediated inactivation of this blood protein. Elucidation of the consequences of the two biological events in patients with the anti-phospholipid syndrome. J Biol Chem 2002;277:2644.
    • (2002) J Biol Chem , vol.277 , pp. 2644
    • Guerin, J.1    Sheng, Y.2    Reddel, S.3
  • 357
    • 0030045467 scopus 로고    scopus 로고
    • Correction of severe thrombocytopenia with chloroquine in the primary antiphospholipid syndrome
    • Suarez IM, Diaz RA, Aguayo Canela D, et al. Correction of severe thrombocytopenia with chloroquine in the primary antiphospholipid syndrome. Lupus 1996;5:81.
    • (1996) Lupus , vol.5 , pp. 81
    • Suarez, I.M.1    Diaz, R.A.2    Aguayo Canela, D.3
  • 358
    • 0024463930 scopus 로고
    • Correction of thrombocytopenia with small dose aspirin in the primary antiphospholipid syndrome
    • Alarcon-Segovia D, Sanchez-Guerrero J. Correction of thrombocytopenia with small dose aspirin in the primary antiphospholipid syndrome. J Rheumatol 1989; 16:1359.
    • (1989) J Rheumatol , vol.16 , pp. 1359
    • Alarcon-Segovia, D.1    Sanchez-Guerrero, J.2
  • 359
    • 0030669192 scopus 로고    scopus 로고
    • Successful therapy with danazol in refractory autoimmune thrombocytopenia associated with rheumatic diseases
    • Blanco R, Martinez-Taboada VM, Rodriguez-Valverde V, et al. Successful therapy with danazol in refractory autoimmune thrombocytopenia associated with rheumatic diseases. Br J Rheumatol 1997;36:1095.
    • (1997) Br J Rheumatol , vol.36 , pp. 1095
    • Blanco, R.1    Martinez-Taboada, V.M.2    Rodriguez-Valverde, V.3
  • 360
    • 0034770561 scopus 로고    scopus 로고
    • The influence of antiphospholipid antibodies on the pregnancy outcome of patients with recurrent spontaneous abortion
    • Heilmann L, von Tempelhoff GF, Kuse S. The influence of antiphospholipid antibodies on the pregnancy outcome of patients with recurrent spontaneous abortion. Clin Appl Thromb Hemost 2001;7:281.
    • (2001) Clin Appl Thromb Hemost , vol.7 , pp. 281
    • Heilmann, L.1    Von Tempelhoff, G.F.2    Kuse, S.3
  • 362
    • 0031022366 scopus 로고    scopus 로고
    • Randomised controlled trial of aspirin and aspirin plus heparin in pregnant women with recurrent miscarriage associated with phospholipid antibodies (or antiphospholipid antibodies)
    • Rai R, Cohen H, Dave M, et al. Randomised controlled trial of aspirin and aspirin plus heparin in pregnant women with recurrent miscarriage associated with phospholipid antibodies (or antiphospholipid antibodies). BMJ 1997;314:253.
    • (1997) BMJ , vol.314 , pp. 253
    • Rai, R.1    Cohen, H.2    Dave, M.3
  • 363
    • 0029934389 scopus 로고    scopus 로고
    • Antiphospholipid antibody-associated recurrent pregnancy loss-treatment with heparin and low dose aspirin is superior to low-dose aspirin alone
    • Kutteh WH. Antiphospholipid antibody-associated recurrent pregnancy loss-treatment with heparin and low dose aspirin is superior to low-dose aspirin alone. Am J Obstet Gynecol 1996;174:1584.
    • (1996) Am J Obstet Gynecol , vol.174 , pp. 1584
    • Kutteh, W.H.1
  • 364
    • 0033784643 scopus 로고    scopus 로고
    • Does aspirin have a role in improving pregnancy outcome for women with the antiphospholipid syndrome? A randomized controlled trial
    • Pattison NS, Chamley LW, Birdsall M, et al. Does aspirin have a role in improving pregnancy outcome for women with the antiphospholipid syndrome? A randomized controlled trial. Am J Obstet Gynecol 2000;183:1008.
    • (2000) Am J Obstet Gynecol , vol.183 , pp. 1008
    • Pattison, N.S.1    Chamley, L.W.2    Birdsall, M.3
  • 365
    • 0035129373 scopus 로고    scopus 로고
    • Use of antithrombotic agents during pregnancy
    • Ginsberg JS, Greer I, Hirsh J. Use of antithrombotic agents during pregnancy. Chest 2001;119 Suppl:122S.
    • (2001) Chest , vol.119 , Issue.SUPPL.
    • Ginsberg, J.S.1    Greer, I.2    Hirsh, J.3
  • 366
    • 0033836411 scopus 로고    scopus 로고
    • Recurrent miscarriage syndrome due to blood coagulation protein/platelet defects: Prevalence, treatment and outcome results
    • DRW Metroplex Recurrent Miscarriage Syndrome Cooperative Group
    • Bick RL. Recurrent miscarriage syndrome due to blood coagulation protein/platelet defects: Prevalence, treatment and outcome results. DRW Metroplex Recurrent Miscarriage Syndrome Cooperative Group. Clin Appl Thromb Hemost 2000;6:115.
    • (2000) Clin Appl Thromb Hemost , vol.6 , pp. 115
    • Bick, R.L.1
  • 367
    • 0032977127 scopus 로고    scopus 로고
    • Low-molecular weight heparin restores in-vitro trophoblast invasiveness and differentiation in presence of immunoglobulin G fractions obtained from patients with antiphospholipid syndrome
    • Di Simone N, Caliandro D, Castellani R, et al. Low-molecular weight heparin restores in-vitro trophoblast invasiveness and differentiation in presence of immunoglobulin G fractions obtained from patients with antiphospholipid syndrome. Hum Reprod 1999;14:489.
    • (1999) Hum Reprod , vol.14 , pp. 489
    • Di Simone, N.1    Caliandro, D.2    Castellani, R.3
  • 368
    • 0030730450 scopus 로고    scopus 로고
    • Heparin and low-dose aspirin restore placental human chorionic gonadotrophin secretion abolished by antiphospholipid antibody-containing sera
    • Di Simone N, Ferrazzani S, Castellani R, et al. Heparin and low-dose aspirin restore placental human chorionic gonadotrophin secretion abolished by antiphospholipid antibody-containing sera. Hum Reprod 1997;12:2061.
    • (1997) Hum Reprod , vol.12 , pp. 2061
    • Di Simone, N.1    Ferrazzani, S.2    Castellani, R.3
  • 369
    • 0027144129 scopus 로고
    • Comparative trial of prednisone plus aspirin versus aspirin alone in the treatment of anticardiolipin antibody-positive obstetric patients
    • Silver RK, MacGregor SN, Sholl JS, et al. Comparative trial of prednisone plus aspirin versus aspirin alone in the treatment of anticardiolipin antibody-positive obstetric patients. Am J Obstet Gynecol 1993;169:1411.
    • (1993) Am J Obstet Gynecol , vol.169 , pp. 1411
    • Silver, R.K.1    MacGregor, S.N.2    Sholl, J.S.3
  • 370
    • 0030746019 scopus 로고    scopus 로고
    • Prednisone and aspirin in women with autoantibodies and unexplained recurrent fetal loss
    • Laskin CA, Bombardier C, Hannah ME, et al. Prednisone and aspirin in women with autoantibodies and unexplained recurrent fetal loss. N Engl J Med 1997;337: 148.
    • (1997) N Engl J Med , vol.337 , pp. 148
    • Laskin, C.A.1    Bombardier, C.2    Hannah, M.E.3
  • 371
    • 0028898993 scopus 로고
    • Intravenous immunoglobulin therapy for the antiphospholipid syndrome in pregnancy
    • Spinnato JA, Clark AL, Pierangeli SS, et al. Intravenous immunoglobulin therapy for the antiphospholipid syndrome in pregnancy. Am J Obstet Gynecol 1995;172:690.
    • (1995) Am J Obstet Gynecol , vol.172 , pp. 690
    • Spinnato, J.A.1    Clark, A.L.2    Pierangeli, S.S.3
  • 372
    • 0027339619 scopus 로고
    • Intravenous immunoglobulin treatment of pregnant patients with recurrent pregnancy losses associated with antiphospholipid antibodies
    • Kaaja R, Julkunen H, Ammala P, et al. Intravenous immunoglobulin treatment of pregnant patients with recurrent pregnancy losses associated with antiphospholipid antibodies. Acta Obstet Gynecol Scand 1993;72:63.
    • (1993) Acta Obstet Gynecol Scand , vol.72 , pp. 63
    • Kaaja, R.1    Julkunen, H.2    Ammala, P.3
  • 373
    • 0033979270 scopus 로고    scopus 로고
    • A multicenter, placebo-controlled pilot study of intravenous immune globulin treatment of antiphospholipid syndrome during pregnancy
    • The Pregnancy Loss Study Group. Branch DW, Peaceman AM, Druzin M, et al. A multicenter, placebo-controlled pilot study of intravenous immune globulin treatment of antiphospholipid syndrome during pregnancy. Am J Obstet Gynecol 2000;182:122.
    • (2000) Am J Obstet Gynecol , vol.182 , pp. 122
    • Branch, D.W.1    Peaceman, A.M.2    Druzin, M.3
  • 374
    • 0037334440 scopus 로고    scopus 로고
    • Randomized study of subcutaneous low molecular weight heparin plus aspirin versus intravenous immunoglobulin in the treatment of recurrent fetal loss associated with antiphospholipid antibodies
    • Triolo G, Ferrante A, Ciccia F, et al. Randomized study of subcutaneous low molecular weight heparin plus aspirin versus intravenous immunoglobulin in the treatment of recurrent fetal loss associated with antiphospholipid antibodies. Arthritis Rheum 2003;48:728.
    • (2003) Arthritis Rheum , vol.48 , pp. 728
    • Triolo, G.1    Ferrante, A.2    Ciccia, F.3
  • 375
    • 0030988198 scopus 로고    scopus 로고
    • Do low-risk pregnant women with antiphospholipid antibodies need to be treated?
    • Organizing Group of the Antiphospholipid Antibody Treatment Trial
    • Cowchock S, Reece EA. Do low-risk pregnant women with antiphospholipid antibodies need to be treated? Organizing Group of the Antiphospholipid Antibody Treatment Trial. Am J Obstet Gynecol 1997;176:1099.
    • (1997) Am J Obstet Gynecol , vol.176 , pp. 1099
    • Cowchock, S.1    Reece, E.A.2
  • 376
    • 0038376616 scopus 로고    scopus 로고
    • Catastrophic antiphospholipid syndrome: International consensus statement on classification criteria and treatment guidelines
    • Catastrophic Antiphospholipid Syndrome Registry Project Group
    • Asherson RA, Cervera R, de Groot PG, et al. Catastrophic Antiphospholipid Syndrome Registry Project Group. Catastrophic antiphospholipid syndrome: International consensus statement on classification criteria and treatment guidelines. Lupus 2003;12:530.
    • (2003) Lupus , vol.12 , pp. 530
    • Asherson, R.A.1    Cervera, R.2    De Groot, P.G.3
  • 377
    • 0037334613 scopus 로고    scopus 로고
    • Identification and characterization of a peptide mimetic that may detect a species of disease-associated anticardiolipin antibodies in patients with the antiphospholipid syndrome
    • Visvanathan S, Scott JK, Hwang KK, et al. Identification and characterization of a peptide mimetic that may detect a species of disease-associated anticardiolipin antibodies in patients with the antiphospholipid syndrome. Arthritis Rheum 2003;48:737.
    • (2003) Arthritis Rheum , vol.48 , pp. 737
    • Visvanathan, S.1    Scott, J.K.2    Hwang, K.K.3
  • 378
    • 0034058651 scopus 로고    scopus 로고
    • Value of prothrombin fragment 1.2 (F 1.2) in the diagnosis of stroke in young patients with antiphospholipid antibodies
    • Ellis MH, Kesler A, Friedman Z, et al. Value of prothrombin fragment 1.2 (F 1.2) in the diagnosis of stroke in young patients with antiphospholipid antibodies. Clin Appl Thromb Hemost 2000;6:61.
    • (2000) Clin Appl Thromb Hemost , vol.6 , pp. 61
    • Ellis, M.H.1    Kesler, A.2    Friedman, Z.3
  • 379
    • 0141476180 scopus 로고    scopus 로고
    • APLASA study: Primary thrombosis prevention in asymptomatic antiphospholipid antibody (APL) patients with low dose aspirin (ASA)
    • Erkan D, Yazici Y, Harrison MJ, et al. APLASA study: Primary thrombosis prevention in asymptomatic antiphospholipid antibody (APL) patients with low dose aspirin (ASA). Lupus 2002;11:573.
    • (2002) Lupus , vol.11 , pp. 573
    • Erkan, D.1    Yazici, Y.2    Harrison, M.J.3
  • 380
    • 0038603016 scopus 로고    scopus 로고
    • The blossoming of evidence-based clinical rheumatology: The Arthritis Research Campaign's Clinical Trials Collaboration in association with the MRC Clinical Trials Unit, BSR and BOA
    • Arthritis Research Campaign's Clinical Trials Committee
    • Cooper C, Choy E, Arthritis Research Campaign's Clinical Trials Committee. The blossoming of evidence-based clinical rheumatology: The Arthritis Research Campaign's Clinical Trials Collaboration in association with the MRC Clinical Trials Unit, BSR and BOA. Rheumatology 2003;42:713.
    • (2003) Rheumatology , vol.42 , pp. 713
    • Cooper, C.1    Choy, E.2
  • 381
    • 0029830719 scopus 로고    scopus 로고
    • Feasibility of a randomized clinical trial for the prevention of recurrent thrombosis in the antiphospholipid syndrome: The WAPS project. Provisional Steering Committee of the Warfarin in Antiphospholipid Syndrome (WAPS) Study
    • Finazzi G, Barbui T. Feasibility of a randomized clinical trial for the prevention of recurrent thrombosis in the antiphospholipid syndrome:the WAPS project. Provisional Steering Committee of the Warfarin in Antiphospholipid Syndrome (WAPS) Study. Ann Med Interne (Paris) 1996;147 Suppl 1:38.
    • (1996) Ann Med Interne (Paris) , vol.147 , Issue.SUPPL. 1 , pp. 38
    • Finazzi, G.1    Barbui, T.2
  • 382
    • 0035673283 scopus 로고    scopus 로고
    • Statins prevent endothelial cell activation induced by antiphospholipid (anti-beta2-glycoprotein I) antibodies: Effect on the proadhesive and proinflammatory phenotype
    • Meroni PL, Raschi E, Testoni C, et al. Statins prevent endothelial cell activation induced by antiphospholipid (anti-beta2-glycoprotein I) antibodies: Effect on the proadhesive and proinflammatory phenotype. Arthritis Rheum 2001;44:2870.
    • (2001) Arthritis Rheum , vol.44 , pp. 2870
    • Meroni, P.L.1    Raschi, E.2    Testoni, C.3
  • 383
    • 0242721975 scopus 로고    scopus 로고
    • Inhibition of the thrombogenic and inflammatory properties of antiphospholipid antibodies by fluvastatin in an in vivo animal model
    • Ferrara DE, Liu X, Espinola RG, et al. Inhibition of the thrombogenic and inflammatory properties of antiphospholipid antibodies by fluvastatin in an in vivo animal model. Arthritis Rheum 2003;48:3272.
    • (2003) Arthritis Rheum , vol.48 , pp. 3272
    • Ferrara, D.E.1    Liu, X.2    Espinola, R.G.3
  • 384
    • 0030745177 scopus 로고    scopus 로고
    • Tissue factor pathway inhibitor: Potential therapeutic applications
    • Bajaj MS, Bajaj SP. Tissue factor pathway inhibitor: Potential therapeutic applications. Thromb Haemost 1997;78:471.
    • (1997) Thromb Haemost , vol.78 , pp. 471
    • Bajaj, M.S.1    Bajaj, S.P.2
  • 385
    • 0242410503 scopus 로고    scopus 로고
    • New approaches to prevention of thrombosis in the antiphospholipid syndrome: Hopes, trials, and tribulations
    • Roubey RAS. New approaches to prevention of thrombosis in the antiphospholipid syndrome: Hopes, trials, and tribulations. Arthritis Rheum 2003;48:3004.
    • (2003) Arthritis Rheum , vol.48 , pp. 3004
    • Roubey, R.A.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.