Infection detection in mice using 99mTc-labeled HYNIC and N 2S2 chelate conjugated to the antimicrobial peptide UBI 29-41

Nuclear Medicine and Biology

Volumn 31, Issue 4, 2004, Pages 503-509

  Welling, Mick M ^a   Visentin, Roberta ^b   Feitsma, Hans I J ^a   Lupetti, Antonella ^a,c   Pauwels, Ernest K J ^a   Nibbering, Peter H ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF PADOVA   (Italy)

^c UNIVERSITY OF PISA   (Italy)

Author keywords

99mTc labeling; Antimicrobial peptide; HYNIC; Infection detection; N2S2; Radiochemistry

Indexed keywords

DIAMINEDITHIOLTHREONYLGLYCYLARGINYLALANYLLYSYLARGINYLARGINYLMETHIONYLGLUTAM INYLTYROSYLASPARAGINYLARGINYLARGININE TC 99M; HYDRAZINONICOTINAMIDE THREONYLGLYCYLARGINYLALANYLLYSYLARGINYLARGINYLMETHIONYLGLUTAMINYLTYROSYLASPARAGI NYLARGINYLARGININE TC 99M; TRACER; UBI 29 41; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL INFECTION; BACTERIUM ADHERENCE; BIOACCUMULATION; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG DISTRIBUTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; KIDNEY CLEARANCE; KLEBSIELLA PNEUMONIAE; MALE; MOUSE; NONHUMAN; SCINTIGRAPHY; SERUM; STAPHYLOCOCCUS AUREUS;

ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; CHELATING AGENTS; DRUG STABILITY; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; METABOLIC CLEARANCE RATE; MICE; OLIGOPEPTIDES; ORGAN SPECIFICITY; ORGANOTECHNETIUM COMPOUNDS; RADIOPHARMACEUTICALS; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; TISSUE DISTRIBUTION;

EID: 1842861604     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2003.11.009     Document Type: Article

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