Synthesis and antimicrobial activity of some new pyrido[3′,2′: 4,5]thieno[3,2-d]-pyrimidine derivatives

Phosphorus, Sulfur and Silicon and the Related Elements

Volumn 179, Issue 3, 2004, Pages 513-520

  Bakhite, Etify A ^a   Abdel Rahman, Abdu E ^a   Al Taifi, Elham A ^a  

^a Assiut University   (Egypt)

Author keywords

Antimicrobial activity; Pyridothienopyrimidines; Spiro compounds; Thieno 2,3 b pyridines

Indexed keywords

8 ACETYL 2 (4 BROMOPHENACYLTHIO) 9 (4 CHLOROPHENYL) 7 METHYLPYRIDO[3',2':4,5]THIENO[3,2 D]PYRIMIDIN 4(3H) ONE; 8 ACETYL 9 (4 CHLOROPHENYL) 7 METHYL 4 OXO 1,2,3,4 TETRAHYDRO 2 THIOXOPYRIDO[3',2':4,5]THIENO[3,2 D]PYRIMIDINE; 8 ACETYL 9 (4 CHLOROPHENYL) 7 METHYLPYRIDO[3',2':4,5]THIENO[3,2 D]PYRIMIDINE 2,4(1H,3H) DIONE; 9 ACETYL 3 (4 BROMOPHENYL) 10 (4 CHLOROPHENYL) 8 METHYLTHIAZOLO[3'',2'' A]PYRIDO[3',2':4,5]THIENO[3,2 D]PYRIMIDIN 5 ONE; ALDEHYDE DERIVATIVE; AMIDE; ANTIINFECTIVE AGENT; CARBON DISULFIDE; CYCLOALKANONE; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG; UREA;

ANTIMICROBIAL ACTIVITY; ARTICLE; ASPERGILLUS FUMIGATUS; CONTROLLED STUDY; DRUG ACTIVITY; DRUG SCREENING; DRUG SYNTHESIS; ESCHERICHIA COLI; FUSARIUM OXYSPORUM; IN VITRO STUDY; MICROCOCCUS; NONHUMAN; REACTION ANALYSIS; SERRATIA;

EID: 1842861513     PISSN: 10426507     EISSN: None     Source Type: Journal    
DOI: 10.1080/10426500490422155     Document Type: Article

References (15)

1. K. Eichenberger, E. Schweizer, and P. Schmidt, U.S. Patent 2,627,76614 (1971); CA., 74, 88638w (1971).
2. A. Burger, Medicinal Chemistry (Wiley-Inter. Sciences, New York, 1970), 3rd ed., vol. 72, pp. 544, 719.
3. Z. Shraideh and A.-K.Sallal, Biomed. Lett., 54, 233 (1997).
4. M. E. Schnute, M. M. Cudahy, and A. Scott, PCT Int. Appl. WO. 00, 53, 610: C.A., 133, 222607g (2000).
5. N. Cho, M. Harada, T. Imaeda, et al., J. Med. Chem., 41(22), 4190 (1998).
6. S. Miki, K Fukuoka, M. Akita, et al., PCT Int, Appl. WO. 99, 09, 033; C.A., 130, 196644h (1999).
7. S. Furuya, N. Choh, N. Suzuki, and T. Imada, PCT Int. Appl. WO. 00,00,493; C.A., 132, 64179s (2000).
8. C. G. Dave, P. R. Shah, K. C. Dave, and V. J. Patel, J. Indian Chem. Soc., 66, 48 (1989).
9. S. Leistner, G. Wagener, M. Guestscharo, and E. Glusa, Pharmazie, 41, 54 (1986).
10. E. A. Bakhite, A. E. Abdel-Rahman, O. S. Mohamed, and E. A. Thabet, Pharmazie, 55, 577 (2000).
11. A. E. Abdel-Rahman, E. A. Bakhite, O. S. Mohamed, and E. A. Thabet, Phosphorus, Sulfur and Silicon, 166, 149 (2000).
12. A. E. Abdel-Rahman, E. A. Bakhite, and E. A. Al-Taifi, J. Chin. Chem. Soc., 49, 223 (2002).
13. L. H. Klemm, T. J. R. Weakely, R. D. Gilbertson, and Y. H. Song, J. Heterocycl. Chem., 35, 1269 (1998).
14. F. Russo, G. Romeo, S. Guccione, et al., Pharmazie, 45, 242 (1990).
15. N. Kalyoncuoglu, S. Rollas, D. Sur-Altiner, Y. Yegenoglu, and O. Ang, Pharmazie, 47, 769 (1992).