Pharmacokinetics of ketotifen fumarate after intravenous, intranasal, oral and rectal administration in rabbits

Biological and Pharmaceutical Bulletin

Volumn 25, Issue 12, 2002, Pages 1614-1618

  Yagi, Naomi ^a   Taniuchi, Yoshikuni ^a   Hamada, Keinosuke ^a   Sudo, Jun Ichi ^a   Sekikawa, Hitoshi ^a  

^a HEALTH SCIENCES UNIVERSITY OF HOKKAIDO   (Japan)

Author keywords

HPLC analysis; Intranasal administration; Ketotifen fumarate; Oral administration; Pharmacokinetic; Rectal administration

Indexed keywords

KETOTIFEN FUMARATE; KETOTIFEN;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; COMPARTMENT MODEL; CONTROLLED STUDY; DOSE RESPONSE; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG LIVER LEVEL; DRUG METABOLISM; FIRST PASS EFFECT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIVER METABOLISM; NONHUMAN; RABBIT; ANIMAL; BLOOD; COMPARATIVE STUDY; INTRANASAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MALE; ORAL DRUG ADMINISTRATION; RECTAL DRUG ADMINISTRATION;

ADMINISTRATION, INTRANASAL; ADMINISTRATION, ORAL; ADMINISTRATION, RECTAL; ANIMALS; AREA UNDER CURVE; INJECTIONS, INTRAVENOUS; KETOTIFEN; MALE; RABBITS;

EID: 1842859829     PISSN: 09186158     EISSN: None     Source Type: Journal    
DOI: 10.1248/bpb.25.1614     Document Type: Article

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