Pharmacokinetics of insulin uptake by ocular tissues and the role of cerebrospinal fluid in optic nerve insulin accumulation following topical insulin application

Optometry

Volumn 75, Issue 3, 2004, Pages 183-188

  Koevary, Steven B ^a   Lam, Vincent ^a   Patsiopoulos, Georgia ^a  

^a NEW ENGLAND COLLEGE OF OPTOMETRY   (United States)

Author keywords

Cerebrospinal fluid; Insulin; Optic nerve; Pharmacokinetics; Topical

Indexed keywords

INSULIN; EYE DROPS;

ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; CEREBROSPINAL FLUID ANALYSIS; CILIARY BODY; CISTERNA MAGNA; COHORT ANALYSIS; CONTROLLED STUDY; CORNEA; DRUG DISTRIBUTION; ENZYME LINKED IMMUNOSORBENT ASSAY; EXTRAOCULAR MUSCLE; FEMALE; IRIS; NONHUMAN; OPTIC NERVE; RAT; SCLERA; STATISTICAL SIGNIFICANCE; ANIMAL; CEREBROSPINAL FLUID; INTRASPINAL DRUG ADMINISTRATION; LEWIS RAT; METABOLISM; PHYSIOLOGY; RETINA; TISSUE DISTRIBUTION; TOPICAL DRUG ADMINISTRATION;

ADMINISTRATION, TOPICAL; ANIMALS; CEREBROSPINAL FLUID; CILIARY BODY; CORNEA; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; INJECTIONS, SPINAL; INSULIN; OPHTHALMIC SOLUTIONS; OPTIC NERVE; RATS; RATS, INBRED LEW; RETINA; SCLERA; TISSUE DISTRIBUTION;

EID: 1842855413     PISSN: 15291839     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1529-1839(04)70038-X     Document Type: Article

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