Anti-nociceptive effect of synthesized di-hydroxy flavones: Possible mechanism

Indian Journal of Experimental Biology

Volumn 40, Issue 11, 2002, Pages 1314-1316

  Girija, K ^a   Kannappa Reddy, M ^a   Viswanathan, S ^a  

^a MADRAS MEDICAL COLLEGE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID; SYNTHESIS (CHEMICAL);

ANTI-NOCICEPTIVE EFFECTS;

BIOCHEMISTRY;

ACETIC ACID DERIVATIVE; ANALGESIC AGENT; FLAVONOID; NALOXONE; NARCOTIC ANTAGONIST; OPIATE RECEPTOR; POTASSIUM CHANNEL;

ANIMAL; ARTICLE; DRUG EFFECT; MALE; METABOLISM; MOUSE; NOCICEPTIVE RECEPTOR; PAIN ASSESSMENT; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ACETIC ACIDS; ANALGESICS; ANIMALS; FLAVONOIDS; MALE; MICE; NALOXONE; NARCOTIC ANTAGONISTS; NOCICEPTORS; PAIN MEASUREMENT; POTASSIUM CHANNELS; RECEPTORS, OPIOID; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 1842853572     PISSN: 00195189     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Ramaswamy S, Padmanabha Pillai N, Gopalakrishnan V & Parmar N S, Analgesic activity of bioflavonoid in mice. Indian J Pharmacol, 12 (1980) 33.
2. Viswanathan S, Thirugnanasambantham P, Bapna J S & Kameswaran L, Flavonoid induced delay of small intestinal transit. Possible mechanism of action. Arch Int Pharmacodyn, 270 (1984) 151.
3. Viswanathan S, Thirugnanasambantham P, Ramaswamy S & Kameswaran L, Studies on the possible tolerance and mechanism of gossypin analgesia. Indian J Exp Biol, 23 (1985) 525.
4. Viswanathan S, Thirugnanasambantham P, Ramaswamy S & Bapna J S, A study on the role of cholinergic and gamma aminobutyric acid systems in the anti-nociceptive effect of gossypin. Clin Exp Physiol Pharmacol, 20 (1993) 193.
5. Thirugnanasambantham P, Viswanathan S, Krishnamurthy V, Mythirayee C, Ramachandran S & Kameswaran L, Analgesic activity of certain flavone derivatives: A structure-activity study. J Ethnopharmacol, 28 (1990) 207.
6. Koster R, Anderson M & De Beer E J, Acetic acid for analgesic screening. Fed Proc, 18 (1959) 412.
7. Shewade D G & Ramaswamy S, Prolactin induced analgesia is dependent on ATP sensitive potassium channels. Clin Exp Pharmacol Physiol, 22 (1995) 635.
8. Berridge T L, Doxey J C & Roach A G, Comparison of the effects of efaroxan and glibenclamide on plasma glucose and insulin levels in rats. Eur J Pharmacol, 213 (1992) 213.
9. Rajendran N N, Thirugnanasambantham P, Parvathavarthini S, Viswanathan S & Ramaswamy S, Modulation by insulin rather than blood glucose of the pain threshold and flavone induced anti-nociception in mice. Indian J Exp Biol, 39 (2001) 1009.