-
1
-
-
2042437650
-
Initial sequencing and analysis of the human genome
-
The Genome International Sequencing Consortium. Initial sequencing and analysis of the human genome. Nature 2001; 409: 860-921
-
(2001)
Nature
, vol.409
, pp. 860-921
-
-
-
2
-
-
0040191763
-
Genomic medicine and the future of health care
-
Sander C. Genomic medicine and the future of health care. Science 2000; 287 (5460): 1977-8
-
(2000)
Science
, vol.287
, Issue.5460
, pp. 1977-1978
-
-
Sander, C.1
-
3
-
-
0034655976
-
Pharmacogenetics and future drug development and delivery
-
Roses AD. Pharmacogenetics and future drug development and delivery. Lancet 2000; 355 (9212): 1358-61
-
(2000)
Lancet
, vol.355
, Issue.9212
, pp. 1358-1361
-
-
Roses, A.D.1
-
4
-
-
0032615942
-
1998 ASHG presidential address. Making genomic medicine a reality
-
Beaudet AL. 1998 ASHG presidential address. Making genomic medicine a reality. Am J Hum Genet 1999; 64 (1): 1-13
-
(1999)
Am J Hum Genet
, vol.64
, Issue.1
, pp. 1-13
-
-
Beaudet, A.L.1
-
5
-
-
0033168459
-
Shattuck lecture: Medical and societal consequences of the Human Genome Project
-
Collins FS. Shattuck lecture: Medical and societal consequences of the Human Genome Project. N Engl J Med 1999; 341 (1): 28-37
-
(1999)
N Engl J Med
, vol.341
, Issue.1
, pp. 28-37
-
-
Collins, F.S.1
-
6
-
-
0004120124
-
-
New York: Oxford University Press
-
Weber WW. Pharmacogenetics. New York: Oxford University Press, 1997
-
(1997)
Pharmacogenetics
-
-
Weber, W.W.1
-
7
-
-
0031011356
-
Human acetyltransferase polymorphisms
-
Grant DM, Hughes NC, Janezic SA, et al. Human acetyltransferase polymorphisms. Mutat Res 1997; 376 (1-2): 61-70
-
(1997)
Mutat Res
, vol.376
, Issue.1-2
, pp. 61-70
-
-
Grant, D.M.1
Hughes, N.C.2
Janezic, S.A.3
-
8
-
-
0034105415
-
Application of genetics and genomics in drug development
-
Polymeropoulos M. Application of genetics and genomics in drug development. Drug Dev Res 2000; 49: 43-5
-
(2000)
Drug Dev Res
, vol.49
, pp. 43-45
-
-
Polymeropoulos, M.1
-
9
-
-
0032616971
-
Inventing the pharmacogenomics business
-
Regalado A. Inventing the pharmacogenomics business. Am J Health Syst Pharm 1999; 56 (1): 40-50
-
(1999)
Am J Health Syst Pharm
, vol.56
, Issue.1
, pp. 40-50
-
-
Regalado, A.1
-
10
-
-
0033569516
-
Pharmacogenomics: Translating functional genomics into rational therapeutics
-
Evans WE, Relling MV. Pharmacogenomics: Translating functional genomics into rational therapeutics. Science 1999; 286 (5439): 487-91
-
(1999)
Science
, vol.286
, Issue.5439
, pp. 487-491
-
-
Evans, W.E.1
Relling, M.V.2
-
11
-
-
0033552342
-
Pharmacogenomics
-
Sadée W. Pharmacogenomics. BMJ 1999; 319 (7220): 1286-9
-
(1999)
BMJ
, vol.319
, Issue.7220
, pp. 1286-1289
-
-
Sadée, W.1
-
13
-
-
0035338343
-
Risks in new drug development: Approval success rates for investigational drugs
-
DiMasi JA. Risks in new drug development: Approval success rates for investigational drugs. Clin Pharmacol Ther 2001; 69 (5): 297-307
-
(2001)
Clin Pharmacol Ther
, vol.69
, Issue.5
, pp. 297-307
-
-
DiMasi, J.A.1
-
14
-
-
0036161237
-
A phase I randomized, multicenter trial of CPX in adult subjects with mild cystic fibrosis
-
McCarty NA, Standaert TA, Teresi M, et al. A phase I randomized, multicenter trial of CPX in adult subjects with mild cystic fibrosis. Pediatr Pulmonol 2002; 33 (2): 90-8
-
(2002)
Pediatr Pulmonol
, vol.33
, Issue.2
, pp. 90-98
-
-
McCarty, N.A.1
Standaert, T.A.2
Teresi, M.3
-
15
-
-
0035191641
-
Pharmacological treatment of the ion transport defect in cystic fibrosis
-
Roomans GM. Pharmacological treatment of the ion transport defect in cystic fibrosis. Expert Opin Investig Drugs 2001; 10 (1): 1-19
-
(2001)
Expert Opin Investig Drugs
, vol.10
, Issue.1
, pp. 1-19
-
-
Roomans, G.M.1
-
16
-
-
0028809482
-
Informed consent for genetic research on stored tissue samples
-
Clayton EW, Steinberg KK, Khoury MJ, et al. Informed consent for genetic research on stored tissue samples. JAMA 1995; 274 (22): 1786-92
-
(1995)
JAMA
, vol.274
, Issue.22
, pp. 1786-1792
-
-
Clayton, E.W.1
Steinberg, K.K.2
Khoury, M.J.3
-
17
-
-
0032962527
-
Recommended policies for uses of human tissue in research, education, and quality control
-
Ad Hoc Committee on Stored Tissue. College of American Pathologists
-
Grizzle W, Grody WW, Noll WW, et al. Recommended policies for uses of human tissue in research, education, and quality control. Ad Hoc Committee on Stored Tissue. College of American Pathologists. Arch Pathol Lab Med 1999; 123 (4): 296-300
-
(1999)
Arch Pathol Lab Med
, vol.123
, Issue.4
, pp. 296-300
-
-
Grizzle, W.1
Grody, W.W.2
Noll, W.W.3
-
19
-
-
0031927741
-
Pharmacogenomics and diagnostics
-
Persidis A. Pharmacogenomics and diagnostics. Nat Biotechnol 1998; 16 (8): 791-2
-
(1998)
Nat Biotechnol
, vol.16
, Issue.8
, pp. 791-792
-
-
Persidis, A.1
-
20
-
-
0034682156
-
Uneasy alliance: Clinical investigators and the pharmaceutical industry
-
Bodenheimer T. Uneasy alliance: Clinical investigators and the pharmaceutical industry. N Engl J Med 2000; 342 (20): 1539-44
-
(2000)
N Engl J Med
, vol.342
, Issue.20
, pp. 1539-1544
-
-
Bodenheimer, T.1
-
21
-
-
0032091881
-
Why pharmacogenomics? Why now?
-
Housman D, Ledley FD. Why pharmacogenomics? Why now? Nat Biotechnol 1998; 16 (6): 492-3
-
(1998)
Nat Biotechnol
, vol.16
, Issue.6
, pp. 492-493
-
-
Housman, D.1
Ledley, F.D.2
-
22
-
-
0033782224
-
Prospective CYP2D6 genotyping as an exclusion criterion for enrollment of a phase III clinical trial
-
Murphy MP, Beaman ME, Clark LS, et al. Prospective CYP2D6 genotyping as an exclusion criterion for enrollment of a phase III clinical trial. Pharmacogenetics 2000; 10 (7): 583-90
-
(2000)
Pharmacogenetics
, vol.10
, Issue.7
, pp. 583-590
-
-
Murphy, M.P.1
Beaman, M.E.2
Clark, L.S.3
-
23
-
-
0035286694
-
Ethical and legal implications of pharmacogenomics
-
Rothstein MA, Epps PG. Ethical and legal implications of pharmacogenomics. Nat Rev Genet 2001; 2 (3): 228-31
-
(2001)
Nat Rev Genet
, vol.2
, Issue.3
, pp. 228-231
-
-
Rothstein, M.A.1
Epps, P.G.2
-
24
-
-
0034737962
-
What makes clinical research ethical?
-
Emanuel EJ, Wendler D, Grady C. What makes clinical research ethical? JAMA 2000; 283 (20): 2701-11
-
(2000)
JAMA
, vol.283
, Issue.20
, pp. 2701-2711
-
-
Emanuel, E.J.1
Wendler, D.2
Grady, C.3
-
25
-
-
0033744498
-
The contribution of molecular markers to the prediction of response in the treatment of breast cancer: A review of the literature on HER-2, p53 and BCL-2
-
Hamilton A, Piccart M. The contribution of molecular markers to the prediction of response in the treatment of breast cancer: A review of the literature on HER-2, p53 and BCL-2. Ann Oncol 2000; 11 (6): 647-63
-
(2000)
Ann Oncol
, vol.11
, Issue.6
, pp. 647-663
-
-
Hamilton, A.1
Piccart, M.2
-
26
-
-
0030793014
-
Eligibility of Alzheimer's disease clinic patients for clinical trials
-
Schneider LS, Olin JT, Lyness SA, et al. Eligibility of Alzheimer's disease clinic patients for clinical trials. J Am Geriatr Soc 1997; 45 (8): 923-8
-
(1997)
J Am Geriatr Soc
, vol.45
, Issue.8
, pp. 923-928
-
-
Schneider, L.S.1
Olin, J.T.2
Lyness, S.A.3
-
27
-
-
0029155843
-
Women in clinical trials: An FDA perspective
-
Sherman LA, Temple R, Merkatz RB. Women in clinical trials: An FDA perspective. Science 1995; 269 (5225): 793-5
-
(1995)
Science
, vol.269
, Issue.5225
, pp. 793-795
-
-
Sherman, L.A.1
Temple, R.2
Merkatz, R.B.3
-
28
-
-
0033659851
-
Clinical trials in children: Problems and pitfalls
-
Kauffman RE. Clinical trials in children: Problems and pitfalls. Paediatr Drugs 2000; 2 (6): 411-8
-
(2000)
Paediatr Drugs
, vol.2
, Issue.6
, pp. 411-418
-
-
Kauffman, R.E.1
-
29
-
-
0036173643
-
Orphan drug product regulation: United States
-
Haffner ME. Orphan drug product regulation: United States. Int J Clin Pharmacol Ther 2002; 40 (2): 84-8
-
(2002)
Int J Clin Pharmacol Ther
, vol.40
, Issue.2
, pp. 84-88
-
-
Haffner, M.E.1
-
30
-
-
0032151399
-
When should "riskier" subjects be excluded from research participation?
-
Wendler D. When should "riskier" subjects be excluded from research participation? Kennedy Inst Ethics J 1998; 8 (3): 307-27
-
(1998)
Kennedy Inst Ethics J
, vol.8
, Issue.3
, pp. 307-327
-
-
Wendler, D.1
-
31
-
-
0037012465
-
Association between CYP2C9 genetic variants and anticoagulation-related outcomes during warfarin therapy
-
Higashi MK, Veenstra DL, Kondo LM, et al. Association between CYP2C9 genetic variants and anticoagulation-related outcomes during warfarin therapy. JAMA 2002; 287 (13): 1690-8
-
(2002)
JAMA
, vol.287
, Issue.13
, pp. 1690-1698
-
-
Higashi, M.K.1
Veenstra, D.L.2
Kondo, L.M.3
-
32
-
-
0033549087
-
The safety of newly approved medicines: Do recent market removals mean there is a problem?
-
Friedman MA, Woodcock J, Lumpkin MM, et al. The safety of newly approved medicines: Do recent market removals mean there is a problem? JAMA 1999; 281 (18): 1728-34
-
(1999)
JAMA
, vol.281
, Issue.18
, pp. 1728-1734
-
-
Friedman, M.A.1
Woodcock, J.2
Lumpkin, M.M.3
-
33
-
-
0345493890
-
Privacy in genetics research
-
Fuller BP, Kahn MJ, Barr PA, et al. Privacy in genetics research. Science 1999; 285 (5432): 1359-61
-
(1999)
Science
, vol.285
, Issue.5432
, pp. 1359-1361
-
-
Fuller, B.P.1
Kahn, M.J.2
Barr, P.A.3
-
34
-
-
0027143872
-
National policy development for the clinical application of genetic diagnostic technologies. Lessons from cystic fibrosis
-
Wilfond BS, Nolan K. National policy development for the clinical application of genetic diagnostic technologies. Lessons from cystic fibrosis. JAMA 1993; 270: (24): 2948-54
-
(1993)
JAMA
, vol.270
, Issue.24
, pp. 2948-2954
-
-
Wilfond, B.S.1
Nolan, K.2
-
35
-
-
0004215041
-
-
Washington, DC: NIH-DOE Working Group on Ethical, Legal, and Social Implications of Human Genome Research. Task Force on Genetic Testing
-
Holtzman NA, Watson MS, editors. Promoting Safe and Effective Genetic Testing in the United States: Final Report of the Task Force on Genetic Testing. Washington, DC: NIH-DOE Working Group on Ethical, Legal, and Social Implications of Human Genome Research. Task Force on Genetic Testing, 1997: 180
-
(1997)
Promoting Safe and Effective Genetic Testing in the United States: Final Report of the Task Force on Genetic Testing
, pp. 180
-
-
Holtzman, N.A.1
Watson, M.S.2
-
36
-
-
0034660560
-
Pharmacogenetics and the practice of medicine
-
Roses AD. Pharmacogenetics and the practice of medicine. Nature 2000; 405 (6788): 857-65
-
(2000)
Nature
, vol.405
, Issue.6788
, pp. 857-865
-
-
Roses, A.D.1
-
37
-
-
0011876588
-
Huntington disease
-
Scriver CR, Sly WS, Childs B, et al., editors. New York: McGraw-Hill
-
Hayden MR, Kremer B. Huntington disease. In: Scriver CR, Sly WS, Childs B, et al., editors. The Metabolic and Molecular Bases of Inherited Disease. 8th Ed. New York: McGraw-Hill, 2001: 5677-701
-
(2001)
The Metabolic and Molecular Bases of Inherited Disease. 8th Ed.
, pp. 5677-5701
-
-
Hayden, M.R.1
Kremer, B.2
-
38
-
-
0002473638
-
Breast cancer
-
Scriver CR, Sly WS, Childs B, et al., editors. New York: McGraw-Hill
-
Couch FJ, Weber BL. Breast cancer. In: Scriver CR, Sly WS, Childs B, et al., editors. The Metabolic and Molecular Bases of Inherited Disease. 8th Ed. New York: McGraw-Hill, 2001: 999-1031
-
(2001)
The Metabolic and Molecular Bases of Inherited Disease. 8th Ed.
, pp. 999-1031
-
-
Couch, F.J.1
Weber, B.L.2
-
39
-
-
0002848852
-
Cystic fibrosis: General overview
-
Tausig LM, Landau LI, editors. Baltimore: Mosby
-
Wilfond BS, Taussig LM. Cystic fibrosis: General overview. In: Tausig LM, Landau LI, editors. Pediatric Respiratory Medicine. Baltimore: Mosby, 1999: 982-90
-
(1999)
Pediatric Respiratory Medicine
, pp. 982-990
-
-
Wilfond, B.S.1
Taussig, L.M.2
-
40
-
-
0001752544
-
Cystic fibrosis
-
Scriver CR, Sly WS, Childs B, et al., editors. New York: McGraw-Hill
-
Welsh MJ, Ramsay BW, Accurso F, et al. Cystic fibrosis. In: Scriver CR, Sly WS, Childs B, et al., editors. The Metabolic and Molecular Bases of Inherited Disease. 8th Ed. New York: McGraw-Hill, 2001: 5121-88
-
(2001)
The Metabolic and Molecular Bases of Inherited Disease. 8th Ed.
, pp. 5121-5188
-
-
Welsh, M.J.1
Ramsay, B.W.2
Accurso, F.3
-
42
-
-
0034034158
-
Genetic polymorphism of thiopurine methyltransferase and its clinical relevance for childhood acute lymphoblastic leukemia
-
McLeod HL, Krynetski EY, Relling MV, et al. Genetic polymorphism of thiopurine methyltransferase and its clinical relevance for childhood acute lymphoblastic leukemia. Leukemia 2000; 14 (4): 567-72
-
(2000)
Leukemia
, vol.14
, Issue.4
, pp. 567-572
-
-
McLeod, H.L.1
Krynetski, E.Y.2
Relling, M.V.3
-
43
-
-
0003869217
-
-
Bethesda (MD): Centers for Disease Control and Prevention. Aug
-
Reported Tuberculosis in the United States 1999. Bethesda (MD): Centers for Disease Control and Prevention. 2000 Aug; Available from URL: www.lungusa.org/advocacy/107/PP107_TB.pdf [Accessed 2002 Oct 2]
-
(2000)
Reported Tuberculosis in the United States 1999
-
-
-
44
-
-
0034723044
-
Polymorphisms in genes involved in neurotransmission in relation to smoking
-
Arinami T, Ishiguro H, Onaivi ES. Polymorphisms in genes involved in neurotransmission in relation to smoking. Eur J Pharmacol 2000; 410 (2-3): 215-26
-
(2000)
Eur J Pharmacol
, vol.410
, Issue.2-3
, pp. 215-226
-
-
Arinami, T.1
Ishiguro, H.2
Onaivi, E.S.3
-
45
-
-
0032481666
-
Case-control study of the D2 dopamine receptor gene and smoking status in lung cancer patients
-
Spitz MR, Shi H, Yang F, et al. Case-control study of the D2 dopamine receptor gene and smoking status in lung cancer patients. J Natl Cancer Inst 1998; 90 (5): 358-63
-
(1998)
J Natl Cancer Inst
, vol.90
, Issue.5
, pp. 358-363
-
-
Spitz, M.R.1
Shi, H.2
Yang, F.3
-
46
-
-
0031810031
-
Depression and self-medication with nicotine: The modifying influence of the dopamine D4 receptor gene
-
Lerman C, Caporasi N, Main D, et al. Depression and self-medication with nicotine: The modifying influence of the dopamine D4 receptor gene. Health Psychol 1998; 17 (1): 56-62
-
(1998)
Health Psychol
, vol.17
, Issue.1
, pp. 56-62
-
-
Lerman, C.1
Caporasi, N.2
Main, D.3
-
47
-
-
0032958815
-
A genetic association for cigarette smoking behavior
-
Sabol SZ, nelson ML, Fisher C, et al. A genetic association for cigarette smoking behavior. Health Psychol 1999; 18 (1): 7-13
-
(1999)
Health Psychol
, vol.18
, Issue.1
, pp. 7-13
-
-
Sabol, S.Z.1
Nelson, M.L.2
Fisher, C.3
-
48
-
-
0034612930
-
Cigarette smoking among adults: United States 1998
-
Centers for Disease Control. Cigarette smoking among adults: United States 1998. MMWR Morb Mortal Wkly Rep 2000; 49 (39): 881-4
-
(2000)
MMWR Morb Mortal Wkly Rep
, vol.49
, Issue.39
, pp. 881-884
-
-
-
49
-
-
0003987981
-
-
Washington, DC: National Academy Press
-
Andrews LB, Fullerton JE, Holtzman F, et al., editors. Assessing Genetic Risks: Implications for Health and Social Policy. Washington, DC: National Academy Press, 1994: 338
-
(1994)
Assessing Genetic Risks: Implications for Health and Social Policy
, pp. 338
-
-
Andrews, L.B.1
Fullerton, J.E.2
Holtzman, F.3
-
50
-
-
0033816359
-
Association between polymorphisms in dopamine metabolic enzymes and tobacco consumption in smokers
-
McKinney EF, Walton RT, Yudkin P, et al. Association between polymorphisms in dopamine metabolic enzymes and tobacco consumption in smokers. Pharmacogenetics 2000; 10 (6): 483-91
-
(2000)
Pharmacogenetics
, vol.10
, Issue.6
, pp. 483-491
-
-
McKinney, E.F.1
Walton, R.T.2
Yudkin, P.3
-
51
-
-
0032874324
-
Ethical issues in the use of genetic markers in occupational epidemiologic research
-
Schulte PA, Lomax GP, Ward EM, et al. Ethical issues in the use of genetic markers in occupational epidemiologic research. J Occup Environ Med 1999; 41 (8): 639-46
-
(1999)
J Occup Environ Med
, vol.41
, Issue.8
, pp. 639-646
-
-
Schulte, P.A.1
Lomax, G.P.2
Ward, E.M.3
-
52
-
-
0032748555
-
Pharmacogenetics and pharmacogenomics: Why is this relevant to the clinical geneticist?
-
Nebert DW. Pharmacogenetics and pharmacogenomics: Why is this relevant to the clinical geneticist? Clin Genet 1999; 56 (4): 247-58
-
(1999)
Clin Genet
, vol.56
, Issue.4
, pp. 247-258
-
-
Nebert, D.W.1
-
53
-
-
0035962322
-
The promise of human genetic databases
-
Lowrance WW. The promise of human genetic databases. BMJ 2001; 322 (7293): 1009-10
-
(2001)
BMJ
, vol.322
, Issue.7293
, pp. 1009-1010
-
-
Lowrance, W.W.1
-
54
-
-
0028872836
-
Report Points to consider: Ethical, legal, and psychosocial implications of genetic testing in children and adolescents
-
ASHG/ACMG. Report Points to consider: Ethical, legal, and psychosocial implications of genetic testing in children and adolescents. Am J Hum Genet 1995; 57: 1233-41
-
(1995)
Am J Hum Genet
, vol.57
, pp. 1233-1241
-
-
-
55
-
-
0027945216
-
The genetic testing of children: Working Party of the Clinical Genetics Society
-
Clarke A. The genetic testing of children: Working Party of the Clinical Genetics Society (UK). J Med Genet 1994; 31 (10): 785-97
-
(1994)
J Med Genet
, vol.31
, Issue.10
, pp. 785-797
-
-
Clarke, A.1
-
56
-
-
0033915078
-
The effect of polymorphisms of the beta (2)-adrenergic receptor on the response to regular use of albuterol in asthma
-
Israel E, Drazen JM, Liggett SB, et al. The effect of polymorphisms of the beta (2)-adrenergic receptor on the response to regular use of albuterol in asthma. Am J Respir Crit Care Med 2000; 162 (1): 75-80
-
(2000)
Am J Respir Crit Care Med
, vol.162
, Issue.1
, pp. 75-80
-
-
Israel, E.1
Drazen, J.M.2
Liggett, S.B.3
-
57
-
-
85047694198
-
Primary care and the human genome project: Into the breach
-
Doukas DJ. Primary care and the human genome project: Into the breach. Arch Fam Med 1993; 2(11): 1179-83
-
(1993)
Arch Fam Med
, vol.2
, Issue.11
, pp. 1179-1183
-
-
Doukas, D.J.1
-
58
-
-
0027179528
-
Physicians' knowledge of genetics and genetic tests
-
Hofman KJ, Tambor ES, Chase GA, et al. Physicians' knowledge of genetics and genetic tests. Acad Med 1993; 68 (8): 625-32
-
(1993)
Acad Med
, vol.68
, Issue.8
, pp. 625-632
-
-
Hofman, K.J.1
Tambor, E.S.2
Chase, G.A.3
-
59
-
-
0034940965
-
Consent and privacy in pharmacogenetic testing
-
Robertson JA. Consent and privacy in pharmacogenetic testing. Nat Genet 2001; 28 (3): 207-9
-
(2001)
Nat Genet
, vol.28
, Issue.3
, pp. 207-209
-
-
Robertson, J.A.1
-
60
-
-
0028029477
-
Increased risk of venous thrombosis in oral-contraceptive users who are carriers of factor V Leiden mutation
-
Vandenbroucke JP, Koster T, Briet E, et al. Increased risk of venous thrombosis in oral-contraceptive users who are carriers of factor V Leiden mutation. Lancet 1994; 344 (8935): 1453-7
-
(1994)
Lancet
, vol.344
, Issue.8935
, pp. 1453-1457
-
-
Vandenbroucke, J.P.1
Koster, T.2
Briet, E.3
-
61
-
-
0033214004
-
Screening for factor V Leiden mutation before prescribing combination oral contraceptives
-
Creinin MD, Lisman R, Strickler RC. Screening for factor V Leiden mutation before prescribing combination oral contraceptives. Fertil Steril 1999; 72 (4): 646-51
-
(1999)
Fertil Steril
, vol.72
, Issue.4
, pp. 646-651
-
-
Creinin, M.D.1
Lisman, R.2
Strickler, R.C.3
|