Bone marrow biopsy: Interpretive guidelines for the surgical pathologist

Advances in Anatomic Pathology

Volumn 10, Issue 1, 2003, Pages 8-26

  Cotelingam, James D ^a  

^a Louisiana State University School of Medicine Shreveport   (United States)

Author keywords

Bone marrow core biopsy; Fluorescence in situ hybridization; Immunohistochemistry; Polymerase chain reaction

Indexed keywords

DNA;

BIOPSY; BONE MARROW; BONE MARROW CELL; BONE MARROW DISEASE; DIAGNOSTIC PROCEDURE; FLOW CYTOMETRY; FLUORESCENCE IN SITU HYBRIDIZATION; GENETICS; HUMAN; IMMUNOHISTOCHEMISTRY; METABOLISM; METHODOLOGY; PATHOLOGY; POLYMERASE CHAIN REACTION; PRACTICE GUIDELINE; REVIEW; STANDARD;

BIOPSY; BONE MARROW; BONE MARROW CELLS; BONE MARROW DISEASES; DNA; FLOW CYTOMETRY; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION, FLUORESCENCE; MOLECULAR DIAGNOSTIC TECHNIQUES; PATHOLOGY, SURGICAL; POLYMERASE CHAIN REACTION; PRACTICE GUIDELINES;

EID: 1842844679     PISSN: 10724109     EISSN: 15334031     Source Type: Journal    
DOI: 10.1097/00125480-200301000-00002     Document Type: Review

References (182)

1. Neumann E. Uber die Bedetung des Knochenmarks fur die Blutbuilding. Centralblatt Med Wiss 1868;6:689.
2. Bizzozero G. Sulla fungione ematopoietica del midollo delle ossa. Zentralbl Med Wissensch 1868;6:885.
3. Mosler F. Klinische Symptome und Therapie der Medullalären Leukemi. Berl Klin Wochenschr 1876;13:233.
4. Turkel H, Bethell FH. Biopsy of bone marrow performed by a new and simple instrument. J Lab Clin Med 1943;28:1246-1251.
5. Cotelingam JD. Bone marrow interpretation: the science and the art. Pathol Case Rev 2000;5:239-251.
6. Foucar K. Bone Marrow Pathology. 2nd ed. Chicago: American Society of Clinical Pathologists Press; 2001.
7. McFarland W, Damashek W. Biopsy of the bone marrow with the Vim-Silverman needle. JAMA 1958;166:1464-1466.
8. Jamshidi K, Swaim WR. Bone marrow biopsy with unaltered architecture. A new biopsy device. J Lab Clin Med 1971;77:2335-2342.
9. Islam A. Bone marrow biopsy needle with core securing device. J Clin Pathol 1982;35:359-364. (Pubitemid 12153635)
10. MananTM bone marrow/aspiration needle MD TechR [package insert]. Gainsville, FL: Medical Device Technologies, Inc.; 1998.
11. Anderson G, Coup AJ. Effects of decalcifying agents on the staining of Mycobacterium tuberculosis. J Clin Pathol 1975;28:744-745.
12. Wong FTS, Wu PC. The influence of decalcifying fluids on the demonstration of Mycobacterium tuberculosis in paraffin sections. Med Lab Sciences 1979;36:153-157. (Pubitemid 9149729)
13. Krause JR. Zenker-glacial acidic acid treatment of bone marrow biopsies. In: Bone Marrow Biopsy. New York: Churchhill Livingston; 1981;209.
14. Arber DA, Johnson RM, Rainer PA, et al. The bone marrow agar section: a morphologic and immunohistochemical evaluation. Mod Pathol 1993;6:592-598.
15. Islam A. Proposal for a classification of acute myeloid leukemia based on plastic embedded bone marrow biopsy sections. Leuk Res 1993;17:421-427. (Pubitemid 23154355)
16. Burns WA, Yook CR. Plastic sections and ultrastructural techniques in the evaluation of bone marrow pathology. Hematol Oncol Clin North Am 1988;2:525-536.
17. Breton-Gorius J, Reyes F. Ultrastructure of human bone marrow cell maturation. Int Rev Cytol 1976;46:251-321.
18. Ghadially FN. Ultrastruct Pathol of the Cell and Matrix. 3rd ed. Boston: Butterworths; 1988.
19. Zucker-Franklin D, Greaves MF, Grossi CE, Marmont AM. Atlas of Blood Cells. 2nd ed. Philadelphia: Lea & Febiger; 1988.
20. Wickramasinghe SN. Bone marrow. In: Histology for Pathologists. 2nd ed. Philadelphia: Lippincott-Raven; 1997:707-742.
21. Barekman CL, Fair KP, Cotelingam JD. Comparative utility of diagnostic bone marrow components: a 10-year study. Am J Hematol 1997;56:37-41. (Pubitemid 27398057)
22. Aboul-Nasr R, Estey EH, Kantarjian HM, et al. Comparison of touch imprints with aspirate smears for evaluating bone marrow specimens. Am J Clin Pathol 1999;111:753-758. (Pubitemid 29250104)
23. Custer RP. An Atlas of the Blood and Bone Marrow. 2nd ed. Philadelphia: WB Saunders; 1974.
24. Beckstead JH. The bone marrow biopsy: a diagnostic strategy. Arch Pathol Lab Med 1986;110:175-179. (Pubitemid 16144930)
25. Brynes RK, McKenna RW, Sundberg RD. Bone marrow aspiration and trephine biopsy: an approach to a thorough study. Am J Clin Pathol 1987;70:753-759.
26. Hyun BH, Gulati GL, Ashton JK. Bone marrow examination: techniques and interpretation. Hematol Oncol Clin N Am 1988;2:513-523.
27. Naeim F. Atlas of Bone Marrow and Blood Pathology. Philadelphia: WB Saunders; 2001.
28. Li C-Y, Yam LT. Cytochemistry and immunohistochemistry in hematologic diagnosis. Hematol Oncol Clin North Am 1994;8:665-681.
29. Pileri SA, Roncador G, Ceccarelli C, et al. Immunohistochemistry of bone-marrow biopsy. Leuk Lymphoma 1997;26 (Suppl 1):69-75. (Pubitemid 28163660)
30. Erber WN, Willis JI, Hoffman GJ. An enhanced immunohistochemical method for staining bone marrow trephine sections. J Clin Pathol 1997;50:389-393. (Pubitemid 27278442)
31. van der Valk P, Mullink H, Huijens PC, et al. Immunohistochemistry in bone marrow diagnosis. Value of a panel of monoclonal antibodies on routinely processed bone marrow biopsies. Am J Surg Pathol 1989;13:97-106. (Pubitemid 19051194)
32. D'Onofrio G, Zini G, Tommasi M, et al. Automated analysis of bone marrow: routine implementation and differences from peripheral blood. Lab Hematol 1998;4:71-79.
33. Fan G, Alvares C, Ismail S, et al. Quantitative and qualitative bone marrow analysis by the Cell-Dyn 4000 Hematologic Analyzer. Mod Pathol 1999;12:190A.
34. Vos JA, Simurdak JH, Davis BJ, et al. Vortex disaggregation for flow cytometry: a tissue preserving method. Mod Pathol 1999;12:147A.
35. McCoy J, Keren DF. Current practices in clinical flow cytometry: a practice survey by the American Society of Clinical Pathologists. Am J Clin Pathol 1999;111:156-160.
36. Willman CL. Acute leukemias: a paradigm for the integration of new technologies in diagnosis and classification. Mod Pathol 1999;12:218-228. (Pubitemid 29093903)
37. Hartsock R, Smith EB, Petty CS. Normal variations with aging in the amount of hematopoietic tissue in bone marrow from the anterior iliac crest. Am J Clin Pathol 1965;43:326-331.
38. Gruppo RA, Lampkin BC, Granger S. Bone marrow cellularity determination: comparison of the biopsy, aspirate, and buffy coat. Blood 1977;49:29-31. (Pubitemid 8019481)
39. Fong TP, Okafor LA, Schmitz TH, et al. An evaluation of cellularity in various types of bone marrow specimens. Am J Clin Pathol 1979;72:812-816. (Pubitemid 10158899)
40. Vaquez MH, Aubertin C. L'anémie pernicieuse d'après conceptions actuelles. Bull Mem Soc Med Hop Paris 1904;21:288.
41. Osgood EE, Seaman AJ. The cellular composition of bone marrow as obtained by sternal puncture. Physiol Rev 1939;24:105-114.
42. Wickramasinghe SN. Normal hematopoiesis. Cellular composition of normal bone marrow. In: Blood and Bone Marrow. Systemic Pathology. 3rd ed. Edinburgh: Churchill Livingstone; 1991;70.
43. Perkins SL. Examination of blood and bone marrow. In: Lee GR, Foerster J, Lukens J, Paraskevas F, Greer JP, Rodgers GM, eds. Wintrobe's Clinical Hematology. 10th ed. Baltimore: Williams & Wilkins; 1999:1;9.
44. Clark P, Normansell DE, Innes DJ, et al. Lymphocyte subsets in normal bone marrow. Blood 1986;67:1600-1606. (Pubitemid 16075963)
45. Horny HP, Wehrmann M, Griesser H, et al. Investigation of bone marrow lymphocyte subsets in normal, reactive, and neoplastic states using paraffin-embedded biopsy specimens. Am J Clin Pathol 1993;99:142-149. (Pubitemid 23059029)
46. O'Donnell LR, Alder SL, Balis UJ, et al. Immunohistochemical reference ranges for B lymphocytes in bone marrow biopsy paraffin sections. Am J Clin Pathol 1995;104:517-523.
47. Algino KM, Thomason RW, King DE, et al. CD20 (Pan-B cell antigen) expression on bone marrow derived T-cells. Am J Clin Pathol 1996;106:78-81. (Pubitemid 26239325)
48. Sternberg PA, Hill RJ. Platelets and megakaryocytes. In: Lee GR, Foerster J, Lukens J, Paraskevas F, Greer JP, Rodgers GM, eds. Wintrobe's Clinical Hematology. 10th ed. Baltimore: Williams & Wilkins; 1999:1;615-660.
49. Wolf BC, Brady K, O'Murchadha MT, et al. An evaluation of immunohistologic stains for immunoglobulin light chains in bone marrow biopsies in benign and malignant plasma cell proliferations. Am J Clin Pathol 1990;94:742-746.
50. Harada H, Asaoku H, Kuramoto A, et al. Phenotypic difference of normal plasma cells from mature myeloma cells. Blood 1993;81:2658-2663. (Pubitemid 23147570)
51. Oski FA, Naiman JL. The bone marrow. In: Oski FA, Naiman JL, eds. Hematologic Problems in the Newborn. 3rd ed. Philadelphia: WB Saunders Co; 1982;20.
52. Naeim F. Pathology of Bone Marrow. 2nd ed. Baltimore: Williams & Wilkins; 1997.
53. Pinkus GS, Pinkus JL. Myeloperoxidase: a specific marker for myeloid cells in paraffin sections. Mod Pathol 1991;4:733-741.
54. Horny HP, Campbell M, Steinke B, et al. Acute myeloid leukemia: immunohistochemical findings in paraffin-embedded bone marrow specimens. Hum Pathol 1990;21:648-655. (Pubitemid 20204954)
55. Dunphy CH, Polski JM, Evans HL, et al. Evaluation of bone marrow specimens with acute myelogenous leukemia for CD34, CD15, CD117, and myeloperoxidase. Arch Pathol Lab Med 2001;125:1063-1069.
56. Warnke RA, Pulford KA, Pallesen G, et al. Diagnosis of myelomonocytic and macrophage neoplasms in routinely processed tissue biopsies with monoclonal antibody KP1. Am J Pathol 1989;135:1089-1095. (Pubitemid 20026528)
57. Horny HP, Parwaresch MR, Lennert K. Bone marrow findings in systemic mastocytosis. Hum Pathol 1985;16:808-814. (Pubitemid 15040816)
58. Li WV, Kapadia SB, Sonmez-Alpan E, et al. Immunohistochemical characterization of mast cell disease in paraffin sections using tryptase, CD68, myeloperoxidase, lysozyme, and CD20 antibodies. Mod Pathol 1996;9:982-988. (Pubitemid 26356740)
59. Horny HP, Sillaber C, Menke D, et al. Diagnostic utility of staining for tryptase in patients with mastocytosis. Am J Surg Pathol 1998;22:1132-1140. (Pubitemid 28411072)
60. Natkunam Y, Rouse RV. Utility of paraffin section immunohistochemistry for C-KIT (CD117) in the differential diagnosis of systemic mast cell disease involving the bone marrow. Am J Surg Pathol 2000;24:81-91. (Pubitemid 30033400)
61. Hanson CA, Abaza M, Sheldon S, et al. Acute biphenotypic leukemia: immunophenotype and cytogenetic analysis. Br J Haematol 1993;84:49-60. (Pubitemid 23158115)
62. Gaffney RL, Lowrey MC, Sciotto CG. Acute lymphoblastic leukemia relapsing as acute myelogenous leukemia: the role of the mixed lineage leukemia (MLL) gene. ASCP Check Sample HP-99, 1999.
63. Mangi MH, Salisbury JR, Mufti GJ. Abnormal localization of immature precursors in the bone marrow of myelodysplastic syndromes: current state of knowledge and future directions. Leuk Res 1991;15:627-639.
64. Heaney ML, Golde DW. Myelodysplasia. N Engl J Med 1999;340:1649-1660. (Pubitemid 29249435)
65. Reddey VB. Topics in bone marrow biopsy pathology: role of marrow topography in myelodysplastic syndromes and evaluation of posttreatment and postbone marrow transplant biopsies. Ann Diagn Pathol 2001;5:110-120.
66. Orazi A, Albitar M, Heerema NA, et al. Hypoplastic myelodysplastic syndromes can be distinguished from acquired aplastic anemia by CD34 and PCNA immunostaining of bone marrow biopsy specimens. Am J Clin Pathol 1997;107:268-274. (Pubitemid 27090230)
67. Brunning R. The proposed WHO classification of MDS and MDS-related acute leukemias. Mod Pathol 1999;12:102.
68. Vardiman JW. Myelodysplastic/myeloproliferative disorders. Mod Pathol 1999;12:104-105.
69. Jaffe ES, Harris NL, Stein H, et al. Tumors of Hematopoietic and Lymphoid Tissue (WHO Classification of Tumors: Pathology and Genetics). Lyon: IARC Press; 2001.
70. van Der Valden VH, te Marvelde JG, Hoogeveen PG, et al. Targeting of the CD33-calicheamicin immunoconjugate Myelotarg (CMA-676) in acute myeloid leukemia: in vivo and in vitro saturation internalization by leukemic and normal myeloid cells. Blood 2001;97:3197-3204.
71. Druker BJ, Talpaz M, Resta D, et al. Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N Eng J Med 2001;334:1031-1037. (Pubitemid 32267972)
72. Hasserjian RP, Boecklin F, Parker S, et al. ST1571 (Imatinib Mesylate) reduces bone marrow cellularity and normalizes morphologic features irrespective of cytogenetic response. Am J Clin Pathol 2002;117:360-367. (Pubitemid 34226070)
73. Applebaum FR, Downing J, Willman C. The biology and therapy of acute myelogenous leukemia. Molecular detection and monitoring of AML 1/ETO transcripts in AML with t(8;21). In: Kaushansky K, McArthur JR, eds. Hematology Education Program, American Society of Hematology. Seattle: Smith, Bucklin & Associates; 1995;23-35.
74. Kowal-Vern A, Cotelingam JD, Schumacher HR. The prognostic significance of pronormoblasts in acute leukemia. Am J Clin Pathol 1992;98:34-40.
75. Mazzella FM, Cotelingam JD, Kowal-Vern A, et al. Proposed WHO classification of acute myeloid leukemia and myelodysplastic syndromes. Mod Pathol 2000;13:101-102.
76. Strauchen JA. B19 Parvovirus infection. In: Diagnostic Histopathology of the Bone Marrow. New York: Oxford University Press; 1996;282-285.
77. Lee GR. Congenital dyserythropoietic anemias. In: Lee GR, Foerster J, Lukens J, Paraskevas F, Greer JP, Rodgers GM, eds. Wintrobe's Clinical Hematology. 10th ed. Baltimore: Williams & Wilkins; 1999:2;1489-1496.
78. Mazzela FM, Kowal-Vern A, Shrit A, et al. Erythroleukemia. Evaluation of 48 cases with reference to classification, cell proliferation, cytogenetics and prognosis. Am J Clin Pathol 1998;110:590-598. (Pubitemid 28491963)
79. Crocker J, Gyde O, Jenkins R. Demonstration of normoblasts in tissue sections by means of an immunohistochemical technique for haemoglobin. J Clin Pathol 1984;37:1312-1313. (Pubitemid 15200275)
80. Sternberg PA. Hill RJ. Platelets and megakaryocytes. In: Lee GR, Foerster J, Lukens J, Paraskevas F, Greer JP, Rodgers GM, eds. Wintrobe's Clinical Hematology. 10th ed. Baltimore: Williams & Wilkins; 1999:1;615-660.
81. Innes DJ, Mills SE, Walker GK. Megakaryocytic leukemia: identification using antifactor VIII immunoperoxidase. Am J Clin Pathol 1982;77:107-110. (Pubitemid 12207580)
82. Calapso P, Vitarelli E, Crisafulli C, et al. Immunocytochemical detection of megakaryocytes by endothelial markers: a comparative study. Pathologica 1992;84:215-223.
83. Chuang SS, Yung YC, Li CY. Von Willebrand factor is the most reliable immunohistochemical marker for megakaryocytes of myelodysplastic syndrome and chronic myeloproliferative disorders. Am J Clin Pathol 2000;113:506-511.
84. Huang MJ, Li CY, Nichols WL, et al. Acute leukemia with megakaryocytic differentiation: a study of 12 cases identified immunocytochemically. Blood 1984;64:427-439. (Pubitemid 14051330)
85. San Miguel JF, Gonzalez M, Canizo MC, et al. Leukemias with megakaryoblastic involvement: clinical, hematologic, and immunologic characteristics. Blood 1988;72:402-407.
86. Ivanyi JL, Kiss A, Telek B, et al. Megakaryocyte markers in myeloproliferative disorders. Acta Histochem 1993;95:79-88. (Pubitemid 23315987)
87. + chronic myeloid leukemia measured by flow cytometry. Am J Clin Pathol 1999;111:185-190.
88. Boultwood J, Lewis S, Waincoat JS. The 5q- syndrome. Blood 1994;84:3253-3260. (Pubitemid 24352886)
89. van den Berghe H, Michaux L. 5q-, twenty five years later:a synopsis. Cancer Genet Cytogenet 1997;94:1-7. (Pubitemid 27133494)
90. Rosse C, Kraemer MJ, Dillon TL, et al. Bone marrow cell populations of normal infants: the predominance of lymphocytes. J Lab Clin Med 1977;89:1225-1240. (Pubitemid 8130195)
91. Farhi DC. Germinal centers in bone marrow. Hematol Pathol 1989;3:133-136.
92. Lambertenghi-Deliliers G, Annaloro C, Soligo D, et al. Incidence and histologic features of bone marrow involvement in malignant lymphomas. Ann Hematol 1992;65:61-65.
93. Ben-Ezra JM, King BE, Harris AC, et al. Staining for Bcl-2 protein helps to distinguish benign from malignant lymphoid aggregates in bone marrow biopsies. Mod Pathol 1994;7:560-564.
94. O'Carroll DI, McKenna RW, Brunning RD. Bone marrow manifestations of Hodgkin's disease. Cancer 1976;38:1717-1728.
95. Bartl R, Frisch B, Burnhardt R, et al. Assessment of bone marrow histology in Hodgkin's disease: correlation with clinical factors. Br J Haematol 1982;51:345-360. (Pubitemid 12045308)
96. Karcher DS. Clinically unsuspected Hodgkin disease presenting initially in the bone marrow of patients infected with the human immunodeficiency virus. Cancer 1993;71:1235-1238. (Pubitemid 23054912)
97. Naughton MJ, Hess JL, Zutter MM, et al. Bone marrow staging in patients with nonHodgkin's lymphoma. Is flow cytometry a useful test? Cancer 1998;82:1154-1159. (Pubitemid 28136531)
98. Munker R, Hasencleaver D, Brosteanu O, et al. Bone marrow involvement in Hodgkin's disease: an analysis of 135 consecutive cases. J Clin Oncol 1995;13:403-409.
99. Schumacher HR. Acute Leukemia: Difficult, Controversial and Automated Analysis. Baltimore: Williams & Wilkins; 1997.
100. Orazi A, Cotton J, Cattoretti G, et al. Terminal deoxynucleotidyl transferase staining in acute leukemia and normal bone marrow in routinely processed paraffin sections. Am J Clin Pathol 1994;102:640-645. (Pubitemid 24337558)
101. Kheiri SA, MacKerrell T, Bonagura VR, et al. Flow cytometry with or without cytochemistry for the diagnosis of acute leukemias. Cytometry 1998;34:82-86.
102. Davis RE, Longacre TA, Cornbleet PJ. Hematogones in the bone marrow of adults. Immunophenotypic features, clinical settings and differential diagnosis. Am J Clin Pathol 1994;102:202-211. (Pubitemid 24320526)
103. Foucar K. Chronic lymphoid leukemias and lymphoproliferative disorders. Mod Pathol 1999;12:141-150. (Pubitemid 29093898)
104. Gala J-L, Guiot Y, Delannoy A, et al. Use of image analysis and immunostaining of bone marrow trephine biopsy specimens to quantify residual disease in patients with B-cell chronic lymphocytic leukemia. Mod Pathol 1999;12:391-399. (Pubitemid 29203329)
105. Shapiro JL, Miller ML, Pohlman B, et al. CD5- B-cell lymphoproliferative disorders presenting in blood and bone marrow. A clinicopathologic study of 40 patients. Am J Clin Pathol 1999;111:477-487. (Pubitemid 29153143)
106. Tworek JA, Singleton TP, Schnitzer B, et al. Flow cytometric and immunohistochemical analysis of small lymphocytic lymphoma, mantle cell lymphoma, and plasmacytoid small lymphocytic lymphoma. Am J Clin Pathol 1998;110:582-589. (Pubitemid 28491962)
107. Andriko JA, Aguilera NS, Chu WS, et al. Waldenström's macroglobulinemia: a clinicopathologic study of 22 cases. Cancer 1997;80:1926-1935. (Pubitemid 27479787)
108. Owen RG, Barrans SL, Richards SJ, et al. Waldenströms macroglobulinemia: development of diagnostic criteria and identification of prognostic factors. Am J Clin Pathol 2001;116:420-428. (Pubitemid 32851976)
109. Schlette EJ, Buesco-Ramos CE, Medeiros LJ. B-cell prolymphocytic leukemia. Pathol Case Rev 2000;5:274-280.
110. Schumacher HR, Cotelingam JD. T-Prolymphocytic leukemia. In: Chronic Leukemia: Approach to Diagnosis. New York: Igaku-Shoin; 1993;269-280.
111. Hounieu H, Chittal SM, AL Saati T, et al. Hairy cell leukemia. Diagnosis of bone marrow involvement in paraffin-embedded sections with monoclonal antibody DBA 44. Am J Clin Pathol 1992;98:26-33.
112. Pittaluga S, Tierens A, Dodoo YL, et al. How reliable is histologic examination of bone marrow trephine biopsy specimens for the staging of nonHodgkin's lymphoma? A study of hairy cell leukemia and mantle cell lymphoma involvement of the bone marrow trephine specimen by histologic immunohistochemical, and polymerase chain reaction techniques. Am J Clin Pathol 1999;111:179-184. (Pubitemid 29054944)
113. Troussard X, Valensi F, Duchayne E, et al. Splenic lymphoma with villous lymphocytes: clinical presentation, biology and prognostic factors in a series of 100 patients. Br J Haematol 1996;93:731-736. (Pubitemid 26167378)
114. McCluggage WG, Bharucha H, el-Agnaf M, et al. B-cell signet ring cell lymphoma of bone marrow. J Clin Pathol 1995;48:275-278.
115. Vasef MA, Medeiros LJ, Koo C, et al. Cyclin D1 immunohistochemical staining is useful in distinguishing mantle cell lymphoma from other low grade B-cell neoplasms in bone marrow. Am J Clin Pathol 1997;108:302-307. (Pubitemid 27371649)
116. Kent SA, Variakojis D, Peterson LC. Comparative study of margin zone lymphoma involving bone marrow. Am J Clin Pathol 2002;117:698-708. (Pubitemid 34457003)
117. Traweek ST, Sheibani K. Monocytoid B-cell lymphoma with bone marrow and peripheral blood involvement at presentation. Am J Clin Pathol 1990;94:117-118.
118. Hodges GF, Lenhardt TM, Cotelingam JD. Bone marrow involvement in large cell lymphoma. Prognostic implications of discordant disease. Am J Clin Pathol 1994;101:305-311. (Pubitemid 24089577)
119. Jones D. Large B-cell lymphoma in the bone marrow. Pathol Case Rev 2000;5:281-286.
120. Franco V. Florena AM, Campesi G. Intrasinusoidal bone marrow infiltration: a possible hallmark of splenic lymphoma. Histopathology 1996;29:571-575. (Pubitemid 26422832)
121. Tucker TJ, Bardales RH, Miranda RN. Intravascular lymphomatosis with bone marrow involvement. Arch Pathol Lab Med 1999;123:952-956.
122. Khalidi HS, Brynes RK, Browne P, et al. Intravascular large B-cell lymphoma: the CD5 antigen is expressed by a subset of cases. Mod Pathol 1998;11:983-988. (Pubitemid 28487219)
123. Estalilla OC, Koo CH, Brynes RK, et al. Intravascular large B-cell lymphoma: a report of five cases initially diagnosed by bone marrow biopsy. Am J Clin Pathol 1999;112:255.
124. Skinnider BF, Connors JM, Gascoyne RD. Bone marrow involvement in T-cell rich B-cell lymphoma. Am J Clin Pathol 1997;108:570-578. (Pubitemid 27459241)
125. Ogata M, Ogata Y, Kohno K, et al. Eosinophilia associated with adult T-cell leukemia: role of interleukin-5 and granulocyte-macrophage colony-stimulating factor. Am J Hematol 1995;59:242-245. (Pubitemid 28485507)
126. Evans HL, Burks E, Viswantatha D, et al. Utility of immunohistochemistry in bone marrow evaluation of T-lineage large granular lymphocyte leukemia. Hum Pathol 2000;31:1266-1273.
127. Hanson CA, Brunning RD, Gajl-Peczalska KJ, et al. Bone marrow manifestations of peripheral T-cell lymphoma. A study of 30 cases. Am J Clin Pathol 1986;86:449-460. (Pubitemid 16006869)
128. Gaulard P, Kanavaros P, Farcet JP, et al. Bone marrow histologic and immunohistochemical findings in peripheral T-cell lymphoma: a study of 38 cases. Hum Pathol 1991;22:331-338.
129. Graham SJ, Sharpe RW, Steinberg SM, et al. The prognostic implications of a bone marrow histopathologic classification system in mycosis fungoides and the Sézary syndrome. Cancer 1993;72:726-734. (Pubitemid 23215257)
130. Salhany KE, Greer JP, Cousar JB, et al. Marrow involvement in cutaneous T-cell lymphoma. Am J Clin Pathol 1989:92;747-754.
131. Fraga M, Brosset P, Schaifer D, et al. Bone marrow involvement in anaplastic large cell lymphoma. Immunohistochemical detection of minimal disease and it's prognostic significance. Am J Clin Pathol 1995;103:82-89.
132. Vega F, Medeiros LJ, Bueso-Ramos C, et al. Hepatosplenic gamma/delta T-cell lymphoma in bone marrow. A sinusoidal neoplasm with blastic cytologic features. Am J Clin Pathol 2001;116:410-419. (Pubitemid 32851975)
133. Coad JE, Olson DJ, Christensen DR, et al. Correlation of PCR-detected clonal gene rearrangements with bone marrow morphology in patients with B-lineage lymphoma. Am J Surg Pathol 1997;21:1047-1056. (Pubitemid 27407289)
134. Medeiros LJ, Carr J. Overview of the role of molecular methods in the diagnosis of malignant lymphoma. Arch Path Lab Med 1999;123:1189-1207.
135. Fader S, Kurzrock R, Estrov Z. Minimal residual disease in hematologic disorders. Arch Pathol Lab Med 1999;123:1030-1034. (Pubitemid 29526662)
136. Wolf BC, Brady K, O'Murchadha MT, et al. An evaluation of immunohistologic stains for immunoglobulin light chains in bone marrow biopsies in benign and malignant plasma cell proliferations. Am J Clin Pathol 1990;94:742-746.
137. Harada H, Asaoku H, Kuramoto A, et al. Phenotypic difference of normal plasma cells from mature myeloma cells. Blood 1993;81:2658-2663. (Pubitemid 23147570)
138. Thiry A, Delvenne P, Fontaine MA, et al. Comparison of bone marrow sections, smears, and immunohistologic staining for immunoglobulin light chains in the diagnosis of benign and malignant plasma cell proliferation. Histopathology 1993;22:423-428. (Pubitemid 23168582)
139. Snapper J, Schneid B. On the influence of stilbamidine upon myeloma cells. Blood 1946;1:534-536.
140. Roberts GT, Khalil SH. Multiple myeloma with bone marrow crystal deposition and marrow fibrosis. Ann Saudi Med 1998;18:432-436. (Pubitemid 29043864)
141. Singh G, Krause JR, Breitfeld V. Bone marrow examination for metastatic tumor: aspirate and biopsy. Cancer 1977;40:2317-2321. (Pubitemid 8245223)
142. Jatoi A, Dallal GE, Nguyen PL. False negative rates of tumor metastases in the histologic examination of bone marrow. Mod Pathol 1999;12:29-32. (Pubitemid 29059163)
143. Mansi JL, Berger U, Wilson P, et al. Detection of tumor cells in bone marrow of patients with prostatic carcinoma by immunocytochemical techniques. J Urol 1988;139:545-548. (Pubitemid 18082886)
144. Lazda EJ, Berry PJ. Bone marrow metastasis in Ewing's sarcoma and peripheral primitive neuroectodermal tumor: an immunohistochemical study. Pediatric & Developmental Pathol 1998;1:125-130. (Pubitemid 128542119)
145. Mathieu MC, Friedman S, Bosq J, et al. Immunohistochemical staining of bone marrow biopsies for detection of occult metastasis in breast cancer. Breast Cancer Res Treat 1990;15:21-26. (Pubitemid 20139595)
146. Dabbs DJ. Diagnostic Immunohistochemistry. New York: Churchill Livingstone; 2002.
147. Hruban RH, Kuhajda FP, Mann RB. Acute myelofibrosis. Immunohistochemical study of four cases and comparison with acute megakaryoblastic leukemia. Am J Clin Pathol 1987;88:578-588. (Pubitemid 18014616)
148. Rywlin AM. Myelofibrosis and osteosclerosis. In: Histopathology of the Bone Marrow. Boston; Little Brown & Co.; 1976;153.
149. Burthem J, Cawley JC. Bone marrow fibrosis of hairy cell leukemia is caused by synthesis and assembly of fibronectin matrix by hairy cells. Blood 1994;15:479-504.
150. Bhargava V, Farhi DC. Bone marrow granulomas. Clinicopathologic findings in 72 cases and review of the literature. Hematol Pathol 1988;2:43-50.
151. Bauermeister DE. Quantitation of bone marrow reticulin: a normal range. Am J Clin Pathol 1971;56:24-31.
152. Diebold J, Molina T, Camilleri-Broët S, et al. Bone marrow manifestations of infectious and systemic diseases observed in bone marrow trephine biopsy. Histopathology 2000;37:199-211.
153. Tefferi A, Li CY. Bone marrow granulomas associated with chronic natural killer cell lymphocytosis. Am J Hematol 1997;54:258-262. (Pubitemid 27148267)
154. Volk EE, Miller ML, Kirkley BA, et al. The diagnostic usefulness of bone marrow cultures in patients with fever of unknown origin. Am J Clin Pathol 1998;110:150-153. (Pubitemid 28357652)
155. Farhi DC, Mason III UG, Horsburgh Jr CR. The bone marrow in disseminated MAI infection. Am J Clin Pathol 1985;83:463-468.
156. Rywlin AM, Ortega R. Lipid granulomas of the bone marrow. Am J Clin Pathol 1972;57:457-462.
157. Conner DH, Chandler FW, Schwartz DA, et al. Pathology of Infectious Disease. Stamford: Appleton and Lange; 1997:1;255.
158. Strauchen JA. Interpretation of iron stores in the bone marrow. In: Diagnostic Histopathology of the Bone Marrow. Oxford: Oxford University Press; 1996;16.
159. Rywlin AM. Bone marrow hemosiderin. In: Histopathology of the Bone Marrow. Boston: Little Brown & Co.; 1976;53-58.
160. Rector JT, Cotelingam JD. Gaucher's disease. ASCP Check Path (Hematopathology) 1996; QAH 96-4.
161. Lee RE, Ellis LD. The storage cells of chronic myeloid leukemia. Lab Invest 1971;24:261-264.
162. Ulirsch RC. Sea Blue histiocytes in chronic myeloid leukemia. ASCP Check Sample 1985; H-4.
163. Brunning RD, McKenna RW. Infection associated hemophagocytic syndrome. In: Rosai J, Sobin LH, eds. Atlas of Tumor Pathology, Bone Marrow. AFIP Fasicle. Washington DC; Armed Forces Institute of Pathology; 1994;9:447-452.
164. McKenna RW, Dehner LP. Oxalosis: an unusual cause of myelophthisis in childhood. Am J Clin Pathol 1976;66:991-997.
165. Boquist L, Lindquist B, Ostberg Y, et al. Primary oxalosis. Am J Med 1973;54:673-681.
166. Gherardi G, Poggi A, Sisca S, et al. Bone oxalosis and renal osteodystrophy. Arch Pathol Lab Med 1980;104:105-111. (Pubitemid 10214721)
167. Graham SJ, Heaton RB, Garvin DF, Cotelingam JD. Whole body pathologic analysis of a patient with thorotrast induced myelodysplasia. Health Phys 1992;63:20-26.
168. Kolodny EH, Tenembaum AL. Bone marrow involvement in storage diseases. In: Nathan DG, Orkin SH, eds. Nathan and Oski's Hematology of Infancy and Childhood. 4th ed. Philadelphia: WB Saunders Co; 1992;1452-1492.
169. Wilkins BS, Jones DB. Immunophenotypic characterization of stromal cells in aspirated human bone marrow samples. Exp Hematol 1998;26:1061-1067. (Pubitemid 28477773)
170. Mehta K, Gascon P, Robboy S. The gelatinous bone marrow (serous atrophy) in patients with AIDS, evidence of excess sulphated glycosaminoglycan. Arch Pathol Lab Med 1992;116:504-508.
171. Wolf BC, Kumar A, Vera JC, et al. Bone marrow morphology and immunology in systemic amyloidosis. Am J Clin Pathol 1986;86:84-88. (Pubitemid 16033663)
172. Rosenthal NS, Farhi DC. Bone marrow findings in connective tissue disease. Am J Clin Pathol 1989;92:650-654. (Pubitemid 19272879)
173. Burkhardt R, Bartl R, Beil E, et al. Myelofibrosis-osteosclerosis syndrome: a review of literature and histomorphology. Adv Biosci 1975;16:9-56.
174. Wolf BC, Neiman RS. Myelofibrosis with myeloid metaplasia: pathophysiologic implications of the correlation between bone marrow changes and progression of splenomegaly. Blood 1985;65:803-809. (Pubitemid 15115504)
175. Vigorita VJ. The bone biopsy protocol for evaluating osteoporosis and osteomalacia. Am J Surg Pathol 1984;8:925-930. (Pubitemid 15161468)
176. Frisch B, Bartl R. Biopsy Interpretation of Bone and Bone Marrow. London: Arnold-Oxford University Press; 1999;27.
177. Teitelbaum SL. Renal osteodystrophy. Human Pathol 1984;15:306-323. (Pubitemid 15153060)
178. Wittels B. Renal osteodystrophy. In: Bennington JL, ed. Surgical Pathology of Bone Marrow: Core Biopsy Diagnosis. Philadelphia: WB Saunders Co; 1985;133-136.
179. Bain BJ, Clark DM, Lampert IA. Osteomalacia. In: Bone Marrow Pathology. London: Blackwell Scientific Publications; 1993;258-259.
180. Becks JS, Nordin BEC. Histological assessment of osteoporosis by the iliac crest biopsy. J Pathol Bacteriol 1960;80:391-397.
181. Frisch B, Lewis SM, Burkhardt R, et al. Paget's disease of bone. In: Biopsy Pathology of Bone and Bone Marrow. New York: Raven Press; 1985;97-100.
182. Milgram JW, Jasty M. Osteopetrosis. A morphologic study of twenty-one cases. J Bone Joint Surg Am 1982;64:912-929. (Pubitemid 12099978)