Isolation of foot-and-mouth disease virus specific bovine antibody fragments from phage display libraries

Journal of Immunological Methods

Volumn 286, Issue 1-2, 2004, Pages 155-166

  Kim, Yong Joo ^a,b   Lebreton, Françoise ^a   Kaiser, Claude ^a   Crucière, Catherine ^a   Rémond, Michelle ^a  

^a INRA   (France)

^b Animal Plant and Fisheries Quarantine and Inspection Agency   (South Korea)

Author keywords

Bovine antibody VH fragment; Bovine serum albumin; BSA; CDR; Complementary determining region; FBS; Foetal bovine serum; Foot and mouth disease virus; O phenylenediamine; OD; OPD; Optical density; PCR; PFU; Phage display library; Polymerase chain reaction

Indexed keywords

BETA6 INTEGRIN; FOOT AND MOUTH DISEASE VACCINE; TRIPLE VACCINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY LIBRARY; ANTIBODY RESPONSE; ARTICLE; BACTERIUM; CATTLE; FOOT AND MOUTH DISEASE; FOOT AND MOUTH DISEASE VIRUS; IMMUNE RESPONSE; INSECT; NONHUMAN; NUCLEOTIDE SEQUENCE; PHAGE DISPLAY; PRIORITY JOURNAL; PROTEIN DOMAIN; SEQUENCE HOMOLOGY; VACCINATION; VIRUS ISOLATION;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, VIRAL; BASE SEQUENCE; BLOTTING, WESTERN; CATTLE; CATTLE DISEASES; CLONING, MOLECULAR; DNA, VIRAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPES; FOOT-AND-MOUTH DISEASE; FOOT-AND-MOUTH DISEASE VIRUS; GENE LIBRARY; IMMUNOGLOBULIN FRAGMENTS; IMMUNOGLOBULIN VARIABLE REGION; MOLECULAR SEQUENCE DATA; PEPTIDE LIBRARY; POLYMERASE CHAIN REACTION;

BACTERIA (MICROORGANISMS); BOS TAURUS; BOVINAE; FOOT-AND-MOUTH DISEASE VIRUS; INSECTA;

EID: 1842840004     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jim.2004.01.002     Document Type: Article

References (73)

1. Aggaral N., Barnett P.V. Antigenic sites of foot-and-mouth disease virus (FMDV): an analysis of the specificities of anti-FMDV antibodies after vaccination of naturally susceptible host species. J. Gen. Virol. 83:2002;775.
2. Aitken R., Hosseini A., MacDuff R. Structure and diversification of the bovine immunoglobulin repertoire. Vet. Immunol. Immunopathol. 72:1999;21.
3. Aktas S., Samuel A.R. Identification of antigenic epitopes on the foot-and-mouth disease virus isolate O1/Manisa/Turkey/69 using monoclonal antibodies. Rev. Sci. Tech.-Off. Int. Epizoot. 19:2000;744.
4. Arbabi Ghahroudi M., Desmyter A., Wyns L., Hamers R., Muyldermans S. Selection and identification of single domain antibody fragments from camel heavy-chain antibodies. FEBS Lett. 414:1997;521.
5. Bachrach H.L. Foot-and-mouth disease and its antigens. Adv. Exp. Med. Biol. 185:1985;27.
6. Baranowski E., Ruiz-Jarabo C.M., Domingo E. Evolution of cell recognition by viruses. Science. 292:2001;1102.
7. Barbas C.F. III, Amberg W., Simoncsits A., Jones T.M., Lerner R.A. Selection of human anti-hapten antibodies from semisynthetic libraries. Gene. 137:1993;57.
8. 1 serotype foot-and-mouth disease virus, from a natural bovine host, recognize similar antigenic features to those defined by the mouse. J. Gen. Virol. 79:1998;1687.
9. Belsham G.J. Distinctive features of foot-and-mouth disease virus, a member of the picornavirus family; aspects of virus protein synthesis, protein processing and structure. Prog. Biophys. Mol. Biol. 60:1993;241.
10. Berens J.S., Wylie D.E., Lopez O.J. Use of a single VH family and long CDR3s in the variable region of cattle heavy chains. Int. Immunol. 9:1997;189.
11. Borrego B., Novella I.S., Giralt E., Andreu D., Domingo E. Distinct repertoire of antigenic variants of foot-and-mouth disease virus in the presence or absence of immune selection. J. Virol. 67:1993;6071.
12. Brown F. Foot-and-mouth disease and beyond: vaccine design, past, present and future. Arch. Virol. 15:1999;179. (Suppl.).
13. Burton D.R., Barbas C.F. III, Persson M.A., Koenig S., Chanock R.M., Lerner R.A. A large array of human monoclonal antibodies to type 1 human immunodeficiency virus from combinatorial libraries of asymptomatic seropositive individuals. Proc. Natl. Acad. Sci. U. S. A. 88:1991;10134.
14. Cai X., Garen A. A melanoma-specific VH antibody cloned from a fusion phage library of a vaccinated melanoma patient. Proc. Natl. Acad. Sci. U. S. A. 93:1996;6280.
15. Cai X., Garen A. Comparison of fusion phage libraries displaying VH or single-chain Fv antibody fragments derived from the antibody repertoire of a vaccinated melanoma patient as a source of melanoma-specific targeting molecules. Proc. Natl. Acad. Sci. U. S. A. 94:1997;9261.
16. Chen J.Y.C., Delbrook K., Dealwis C., Mimms L., Mushahwar I.K., Mandecki W. Discontinuous epitopes of hepatitis B surface antigen derived from a filamentous phage peptide library. Proc. Natl. Acad. Sci. U. S. A. 93:1996;1997.
17. Chothia C., Lesk A.M. Canonical structures for the hypervariable regions of immunoglobulins. J. Mol. Biol. 196:1987;901.
18. Chothia C., Novotny J., Bruccoleri R., Karplus M. Domain association in immunoglobulin molecules. The packing of variable domains. J. Mol. Biol. 186:1985;651.
19. Clackson T., Hoogenboom H.R., Griffiths A.D., Winter G. Making antibody fragments using phage display libraries. Nature. 352:1991;624.
20. Collet T.A., Roben P., O'Kennedy R., Barbas C.F. III, Burton D.R., Lerner R.A. A binary plasmid system for shuffling combinatorial antibody libraries. Proc. Natl. Acad. Sci. U. S. A. 89:1992;10026.
21. Crowther J.R., Farias S., Carpenter W.C., Samuel A.R. Identification of a fifth neutralizable site on type O foot-and-mouth disease virus following characterization of single and quintuple monoclonal antibody escape mutants. J. Gen. Virol. 74:1993;1547.
22. Davies E.L., Smith J.S., Birkett C.R., Manser J.M., Anderson-Dear D.V., Young J.R. Selection of specific phage-display antibodies using libraries derived from chicken immunoglobulin genes. J. Immunol. Methods. 186:1995;125.
23. Duque H., Baxt B. Foot-and-mouth disease virus receptors: comparison of bovine alpha(V) integrin utilization by type A and O viruses. J. Virol. 77:2003;2500.
24. Feigelstock D.A., Mateu M.G., Valero M.L., Andreu D., Domingo E., Palma E.L. Emerging foot-and-mouth disease virus variants with antigenically critical amino acid substitutions predicted by model studies using reference viruses. Vaccine. 14:1996;97.
25. Germaschewski V., Murray K. Identification of polyclonal serum specificities with phage-display libraries. J. Virol. Methods. 58:1996;21.
26. Hamers-Casterman C., Atarhouch T., Muyldermans S., Robinson G., Hamers C., Songa E.B., Bendahman N., Hamers R. Naturally occurring antibodies devoid of light chains. Nature. 363:1993;446.
27. Hoogenboom H.R., de Bruine A.P., Hufton S.E., Hoet R.M., Arends J.W., Roovers R.C. Antibody phage display technology and its applications. Immunotechnology. 4:1998;1.
28. Holguin A., Hernandez J., Martinez M.A., Mateu M.G., Domingo E. Differential restrictions on antigenic variation among antigenic sites of foot-and-mouth disease virus in the absence of antibody selection. J. Gen. Virol. 78:1997;601-609.
29. Jackson T., Sheppard D., Denyer M., Blakemore W., King A.M. The epithelial integrin alphaV beta6 is a receptor for foot-and-mouth disease virus. J. Virol. 74:2000;4949.
30. Kabat E.A., Wu T.T., Perry H.M., Gottesman K.S., Foeller C. Sequences of Proteins of Immunological Interest. 4th edition:1991;United States Department of Health and Human Services, Washington, DC.
31. Kaushik A., Shojaei F., Saini S.S. Novel insight into antibody diversification from cattle. Vet. Immunol. Immunopathol. 87:2002;347.
32. Kay B.K., Winter J., McCafferty J. Phage Display of Peptides and Proteins, a Laboratory Manual. 1996;Academic Press, San Diego.
33. Kitching R.P., Knowles N.J., Samuel A.R., Donaldson A.I. Development of foot-and-mouth disease virus strain characterisation - a review. Trop. Anim. Health Prod. 21:1989;153.
34. Krebs O., Ahl R., Straub O.C., Marquardt O. Amino acid changes outside the G-H loop of capsid protein VP1 of type O foot-and-mouth disease virus confer resistance to neutralization by antipeptide G-H serum. Vaccine. 11:1993;359.
35. Lang I.M., Barbas C.F. III, Schleef R.R. Recombinant rabbit Fab with binding activity to type-1 plasminogen activator inhibitor derived from a phage-display library against human alpha-granules. Gene. 172:1996;295.
36. Li Y., Kilpatrick J., Whitelam G.C. Sheep monoclonal antibody fragments generated using a phage display system. J. Immunol. Methods. 236:2000;133.
37. Lopez O., Perez C., Wylie D. A single VH family and long CDR3s are the targets for hypermutation in bovine immunoglobulin heavy chains. Immunol. Rev. 162:1998;55.
38. Marks J.D., Hoogenboom H.R., Bonnert T.P., McCafferty J., Griffiths A.D., Winter G. By-passing immunization. Human antibodies from V-gene libraries displayed on phage. J. Mol. Biol. 222:1991;581.
39. Martinez M.A., Dopazo J., Hernandez J., Mateu M.G., Sobrino F., Domingo E., Knowles N.J. Evolution of the capsid protein genes of foot-and-mouth disease virus: antigenic variation without accumulation of amino acid substitutions over six decades. J. Virol. 66:1992;3557.
40. Mason P., Berinstein A., Baxt B., Parsells R., Kang A., Rieder E. Cloning and expression of a single-chain antibody fragment specific for foot-and-mouth disease virus. Virology. 224(2):1996;548.
41. Mateu M.G. Antibody recognition of picornaviruses and escape from neutralization: a structural view. Virus Res. 38:1995;1.
42. Mateu M.G., Hernandez J., Martinez M.A., Feigelstock D., Lea S., Perez J.J., Giralt E., Stuart D., Palma E.L., Domingo E. Antigenic heterogeneity of a foot-and-mouth disease virus serotype in the field is mediated by very limited sequence variation at several antigenic sites. J. Virol. 68:1994;1407.
43. Mateu M.G., Andrew D., Domingo E. Antibodies raised in a natural host and monoclonal antibodies recognize similar antigenic features of foot-and-mouth disease virus. Virology. 210:1995;120.
44. Mateu M.G., Camarero J.A., Giralt E., Andrew D., Domingo E. Direct evaluation of the immunodominance of a major antigenic site of foot-and-mouth disease virus in a natural host. Virology. 206:1995;298.
45. McCullough K.C., Crowther J.R., Butcher R.N. Alteration in antibody reactivity with foot-and-mouth disease virus (FMDV) 146S antigen before and after binding to a solid phase or complexing with specific antibody. J. Immunol. Methods. 82(1):1985;91.
46. McCullough K.C., De Simone F., Brocchi E., Capucci L., Crowther J.R., Kihm U. Protective immune response against foot-and-mouth disease. J. Virol. 66:1992;1835.
47. Muyldermans S. Single domain camel antibodies: current status. J. Biotechnol. 74:2001;277.
48. Muyldermans S., Atarhouch T., Saldanha J., Barbosa J.A., Hamers R. Sequence and structure of VH domain from naturally occurring camel heavy chain immunoglobulins lacking light chains. Protein Eng. 7:1994;1129.
49. Neff S., Mason P.W., Baxt B. High-efficiency utilization of the bovine integrin alpha V beta 3 as a receptor for foot-and-mouth disease virus is dependent on the bovine beta 3 subunit. J. Virol. 74:2000;7298.
50. Nemerow G.R., Stewart P.L. Antibody neutralization epitopes and integrin binding sites on non enveloped viruses. Virology. 288:2001;189.
51. O'Brien P.M., Aitken R., O'Neil B.W., Campo M.S. Generation of native bovine mAbs by phage display. Proc. Natl. Acad. Sci. U. S. A. 96:1999;640.
52. Padlan E.A. Anatomy of the antibody molecule. Mol. Immunol. 31:1994;169.
53. Parng C.L., Hansal S., Goldsby R.A., Osborne B.A. Gene conversion contributes to Ig light chain diversity in cattle. J. Immunol. 157(12):1996;5478.
54. Reiter Y., Schuck P., Boyd L.F., Plaksin D. An antibody single-domain phage display library of a native heavy chain variable region: isolation of functional single-domain VH molecules with a unique interface. J. Mol. Biol. 290:1999;685.
55. Rieder E., Baxt B., Lubroth J., Mason P.W. Vaccines prepared from chimeras of foot-and-mouth disease virus (FMDV) induce neutralizing antibodies and protective immunity to multiple serotypes of FMDV. J. Virol. 68:1994;7092.
56. Saini S.S., Hein W.R., Kaushik A. A single predominantly expressed polymorphic immunoglobulin VH gene family, related to mammalian group I, clan II, is identified in cattle. Mol. Immunol. 34:1997;641.
57. Sambrook J., Fritsch E.F., Maniatis T. Molecular Cloning. A Laboratory Manual. 2nd ed. 1989;Cold Spring Harbor Laboratory Press, New York.
58. 3 Resende to immunological pressure exerted in vitro by antiviral polyclonal sera. Virus Res. 36:1995;77.
59. Schmitz U., Versmold A., Kaufmann P., Frank H.G. Phage display: a molecular tool for the generation of antibodies. A review. Placenta. 21(Suppl. A):2000;S106.
60. Schofield D.J., Glamann J., Emerson S.U., Purcell R.H. Identification by phage display and characterization of two neutralizing chimpanzee monoclonal antibodies to the hepatitis E virus capsid protein. J. Virol. 74:2000;5548.
61. Sinclair M.C., Gilchrist J., Aitken R. Molecular characterization of bovine V lambda regions. J. Immunol. 155:1995;3068.
62. Sobrino F., Martinez M.A., Carillo C., Beck E. Antigenic variation of foot-and-mouth disease virus of serotype C during propagation in the field is mainly restricted to only one structural protein (VP1). Virus Res. 14:1989;273.
63. Tanha J., Dubuc G., Hirama T., Narang S.A., MacKenzie C.R. Selection by phage display of llama conventional V(H) fragments with heavy chain antibody V(H)H properties. J. Immunol. Methods. 263(1-2):2002;97.
64. Travis M.A., Humphries J.D., Humphries M.J. An unraveling tale of how integrins are activated from within. Trends Pharmacol. Sci. 4:2003;192.
65. Triantafilou M., Triantafilou K., Wilson K.M., Takada Y., Fernandez N. High affinity interactions of Coxsackievirus A9 with integrin alphavbeta3 (CD51/61) require the CYDMKTTC sequence of beta3, but do not require the RGD sequence of the CAV-9 VP1 protein. Hum. Immunol. 61(5):2000;453.
66. Verdaguer N., Fita I., Domingo E., Mateu M.G. Efficient neutralization of foot-and-mouth disease virus by monovalent antibody binding. J. Virol. 71(12):1997;9813-9816.
67. Ward E.S., Gussow D., Griffiths A.D., Jones P.T., Winter G. Binding activities of a repertoire of single immunoglobulin variable domains secreted from Escherichia coli. Nature. 341:1989;544.
68. Winter G., Griffiths A.D., Hawkins R.E., Hoogenboom H.R. Making antibodies by phage display technology. Annu. Rev. Immunol. 12:1994;433.
69. Xie Q.-C., McCahon D., Crowther J.R., Belsham G.J., Mc Cullough K.C. Neutralization of foot-and-mouth disease virus can be mediated through any of at least three separate antigenic sites. J. Gen. Virol. 68:1987;1637.
70. Xiong J.-P., Stehle T., Diefenbach B., Zhang R., Dunker R., Scott D.L., Joachimiak A., Goodman S.L., Arnaout M.A. Crystal structure of the extracellular segment of integrin αVβ3. Science. 294:2001;339.
71. Xiong J.-P., Stehle T., Zhang R., Joachimiak A., Frech M., Goodman S.L., Arnaout M.A. Crystal structure of the extracellular segment of integrin αVβ3 in complex with an Arg-Gly-Asp ligand. Science. 296:2002;151.
72. Xu J.L., Davis M.M. Diversity in the CDR3 region of V(H) is sufficient for most antibody specificities. Immunity. 13:2000;37.
73. Yamanaka H.I., Inoue T., Ikeda-Tanaka O. Chicken monoclonal antibody isolated by a phage display system. J. Immunol. 157:1996;115.