Platinum(II)-catalyzed addition of alcohols to alkynes

Tetrahedron Letters

Volumn 45, Issue 19, 2004, Pages 3787-3788

  Hartman, John W ^a   Sperry, Luke ^a  

^a WESTERN ILLINOIS UNIVERSITY   (United States)

Author keywords

Acetal; Alcohol addition; Alkyne; Catalysis; Hydration; Platinum

Indexed keywords

ACETAL DERIVATIVE; ALCOHOL DERIVATIVE; ALKYNE; PLATINUM;

ARTICLE; CATALYSIS; STEREOCHEMISTRY; SYNTHESIS;

EID: 1842839855     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2004.03.069     Document Type: Article

References (7)

1. Hiscox W., Jennings P.W. Organometallics. 9:1990;1997.
2. Hartman J.W., Hiscox W.C., Jennings P.W. J. Org. Chem. 58:1993;7613.
3. Jennings P.W., Hartman J.W., Hiscox W.C. Inorg. Chim. Acta. 222:1994;317.
4. General procedure for alcohol addition reactions: To a flame-dried 25-mL-round bottomed flask fitted with a septum and stirbar were added 10 mL anhydrous THF, 18 mmol alcohol, 6 mmol alkyne, 1 mol % platinum(II) (as Zeise's Dimer or a simple dihalide salt), and 2 mol % co-catalyst. The reaction mixture was then allowed to stir at room temperature for at least 12 h. The product was then isolated by Kugelrohr bulb-to-bulb distillation, and the distillate analyzed by capillary gas chromatography.
5. Hartman, J. W. Ph.D. Thesis, Montana State University, 1996.
6. Appleton T.G., Berry R.D., Davis C.A., Hall J.R., Kimlin H.A. Inorg. Chem. 23:1984;3514.
7. Appleton T.G., Hall J.R., Neale D.W. Inorg. Chim. Acta. 104:1985;19.