Stimulation of spleen cells in vitro by nanospheric particles containing antigen

Journal of Controlled Release

Volumn 86, Issue 1, 2003, Pages 25-32

  Eyles, J E ^a   Bramwell, V W ^b   Singh, J ^b   Williamson, E D ^a   Alpar, H Oya ^b  

^a DEFENCE SCIENCE AND TECHNOLOGY LABORATORY   (United Kingdom)

^b UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Adjuvant; Immunization; Nanoparticles; Vaccine delivery systems

Indexed keywords

ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 6; NANOPARTICLE; POLYLACTIDE; TETANUS TOXOID; LACTIC ACID; MICROSPHERE; POLYGLYCOLIC ACID; POLYLACTIC ACID POLYGLYCOLIC ACID COPOLYMER; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER; POLYMER; TETANUS TOXIN;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; CELL CULTURE; CELL PROLIFERATION; CELL SUSPENSION; COCULTURE; CONTROLLED STUDY; CYTOTOXICITY; FEMALE; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN CELL; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; COMPARATIVE STUDY; CYTOLOGY; DRUG EFFECT; IMMUNOLOGY; METABOLISM; METHODOLOGY; NANOTECHNOLOGY; SPLEEN;

ANIMALS; ANTIGENS; CELLS, CULTURED; FEMALE; INTERFERON TYPE II; INTERLEUKIN-6; LACTIC ACID; MICE; MICE, INBRED BALB C; MICROSPHERES; NANOTECHNOLOGY; POLYGLYCOLIC ACID; POLYMERS; SPLEEN; TETANUS TOXIN;

EID: 1842837847     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(02)00296-1     Document Type: Article

References (14)

1. Cox J.C., Coulter A.R. Adjuvants - a classification and review of their modes of action. Vaccine. 15:1997;248-256.
2. Cox J., Coulter A. Prospects for the development of new vaccine adjuvants. Biodrugs. 12:1999;439-453.
3. Allison C. The mode of action of immunological adjuvants. Dev. Biol. Stand. 92:1998;3-11.
4. Kreuter J., Haenzel L. Mode of action of immunological adjuvants. Infect. Immun. 19:1978;667-672.
5. Lanzavecchia A. Receptor-mediated antigen uptake and its effect on antigen presentation to class II restricted T lymphocytes. Annu. Rev. Immunol. 8:1993;773-793.
6. Galelli A., Charlot B., Dériaud E., Leclerc C. Cells do not present antigen covalently linked to microspheres. Immunology. 79:1993;69-76.
7. Gengoux C., Leclerc C. In vivo induction of CD4+ T cell responses by antigens covalently linked to synthetic microspheres does not require adjuvant. Int. Immunol. 7:1995;45-53.
8. Vidard L., Kovacsovis-Bankowski M., Kraft S.-K., Chen L.B., Benacerraf B., Rock K.L. Analysis of MHC class II presentation of particulate antigens by B lymphocytes. J. Immunol. 156:1996;2809-2818.
9. Raychaudhuri S., Rock K.L. Fully mobilizing host defense: building better vaccines. Nat. Biotechnol. 16:1998;1025-1031.
10. Fraser P., Koziel H., Ezekowitz R.A.B. The serum mannose-binding protein and the macrophage mannose receptor are pattern recognition that link innate and adaptive immunity. Semin. Immunol. 10:1998;363-372.
11. Bendelac M.N., Rivera S.H., Parck J.H. Mouse CD-1 specific NK1 T cells: development, specificity and function. Annu. Rev. Immunol. 15:1997;535-562.
12. + cells. Annu. Rev. Immunol. 12:1994;635-673.
13. Mosmann T.R., Coffman R.L. Th1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu. Rev. Immunol. 7:1989;145-173.
14. Romagnani S. Lymphokine production by human T cells in disease states. Annu. Rev. Immunol. 12:1994;227-257.