Susceptibility to IVM in a field strain of Haemonchus contortus subjected to four treatments in a closed sheep-goat flock in Kenya

Veterinary Parasitology

Volumn 110, Issue 3-4, 2003, Pages 235-240

  Gatongi, P M ^a   Njoroge, J M ^b,c   Scott, M E ^b   Ranjan, S ^b,d   Gathuma, J M ^e   Munyua, W K ^e   Cheruiyot, H ^a   Prichard, Roger K ^b  

^a KENYA AGRICULTURAL RESEARCH INSTITUTE   (Kenya)

^b MCGILL UNIVERSITY   (Canada)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

^d ZOETIS   (United States)

^e UNIVERSITY OF NAIROBI   (Kenya)

Author keywords

Faecal egg count reduction; Goats; Haemonchus contortus; IVM; Larval migration inhibition; Resistance; Sheep; Susceptibility; Total worm count

Indexed keywords

IVERMECTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC SENSITIVITY; ARTICLE; DOSE RESPONSE; GOAT; HAEMONCHUS CONTORTUS; HERD; KENYA; LARVA; LD 50; NONHUMAN; PARASITE IDENTIFICATION; PARASITE SURVIVAL; SHEEP; STRAIN DIFFERENCE; WORM; ANIMAL; CLINICAL TRIAL; DISEASE PREDISPOSITION; DRUG EFFECT; DRUG RESISTANCE; FECES; FEMALE; GOAT DISEASE; HAEMONCHUS; MALE; PARASITOLOGY; SHEEP DISEASE; SURVIVAL RATE; TRICHOSTRONGYLOSIS;

ANIMALIA; CAPRA HIRCUS; HAEMONCHUS CONTORTUS; OVIS ARIES;

ANIMALS; DISEASE SUSCEPTIBILITY; DRUG RESISTANCE; FECES; FEMALE; GOAT DISEASES; GOATS; HAEMONCHIASIS; HAEMONCHUS; IVERMECTIN; KENYA; LETHAL DOSE 50; MALE; SHEEP DISEASES; SHEEP, DOMESTIC; SURVIVAL RATE;

EID: 1842837063     PISSN: 03044017     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-4017(02)00318-7     Document Type: Article

References (17)

1. Bjorn H., Monrad J., Kassuku A.A., Nansen P. Resistance of benzimidazoles in Haemonchus contortus of sheep in Tanzania. Acta Trop. 48:1991;59-67.
2. Coles G.C., Bauer C., Borgsteede F.H.M., Geerts S., Klei T.R., Taylor M.A., Waller P.J. World association for the advancement of veterinary parasitology (WAAVP) methods for the detection of anthelmintic resistance in nematodes of veterinary importance. Vet. Parasitol. 44:1992;35-44.
3. Conder G.A., Campbell R.K. Chemotherapy of nematode infections of veterinary importance with special reference to drug resistance. Adv. Parasitol. 35:1995;2-84.
4. Gatongi P.M., Scott M.E., Ranjan S., Gathuma J.M., Munyua W.K., Cheruiyot H., Prichard R.K. Effects of three nematode anthelmintic treatment regimes on flock performance of sheep and goats under extensive management in semi-arid Kenya. Vet. Parasitol. 68:1997;323-336.
5. Jackson F. Anthelmintic resistance - the state of play. Br. Vet. J. 149:1993;123-138.
6. Keith R.K. The differentiation of the infective larvae of some common nematode parasites. Aust. J. Zool. 1:1953;223-235.
7. Kelly J.D., Whitlock H.V., Thompson H.G., Hall C.A., Martin I.C.A., LeJambre L.F. Physiological characteristics of free-living and parasitic stages of strains of Haemonchus contortus susceptible or resistant to benzimidazole anthelmintics. Res. Vet. Sci. 25:1978;376-385.
8. Maingi N. Resistance to thiabendazole, fenbendazole and levamisole in Haemonchus and Trichostrongylus species in sheep on a Kenyan farm. Vet. Parasitol. 39:1991;285-291.
9. Maingi N., Scott M.E., Prichard R.K. Effects of selection pressure for thiabendazole resistance on fitness of Haemonchus contortus in sheep. Parasitology. 100:1990;327-335.
10. Ministry of Agriculture, Fisheries and Food, 1986. Manual of Veterinary Parasitological Laboratory Techniques, Her Majesty's Stationery Office, London, p. 159.
11. Mwamachi D.M., Audho J.O., Thorpe W., Baker R.L. Evidence for multiple anthelmintic resistance in sheep and goats reared under the same management in coastal Kenya. Vet. Parasitol. 60:1995;303-313.
12. Njanja J.C., Wescott R.B., Ruvuna F. Comparison of ivermectin and thiabendazole for treatment of naturally occurring nematode infections of goats in Kenya. Vet. Parasitol. 23:1987;205.
13. Shoop W.L. Ivermectin resistance. Parasitol. Today. 9:1993;154-159.
14. Wagland B.M., Jones W.O., Hribar L., Bendixsen T., Emery D.L. A new simplified assay for larval migration inhibition. Int. J. Parasitol. 22:1992;1183-1185.
15. Waller, P.J., Prichard, R.K., 1986. Drug resistance in nematodes. In: Campbell, W.C., Rew, R.S. (Eds.), Chemotherapy of Parasitic Diseases. Plenum Press, New York, pp. 337-362.
16. Waruiru R.M., Maingi N., Gicanga E.J. The prevalence of anthelmintic resistance in sheep in three districts of Kenya. Bull. Anim. Health Prod. Afr. 39:1991;423-428.
17. Waruiru R.M., Kogi J.K., Weda E.H., Ngotho J.W. Multiple anthelmintic resistance on a goat farm in Kenya. Vet. Parasitol. 75:1998;191-197.