Antisense inhibition of Flk-1 by oligonucleotides composed of 2′-deoxy-2′-fluoro-β-D-arabino- and 2′-deoxy-nucleosides

Canadian Journal of Physiology and Pharmacology

Volumn 80, Issue 10, 2002, Pages 951-961

  Lacombe, Julie ^a,b   Viazovkina, Ekaterina ^c   Bernatchez, Pascal N ^a,b   Galarneau, Annie ^c   Damha, Masad J ^c   Sirois, Martin G ^a,b  

^a MONTREAL HEART INSTITUTE   (Canada)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

2 F ANA nucleosides; Antisense DNA; Flk 1; Mixed backbone antisense; VEGF

Indexed keywords

2' DEOXY 2' FLUORO BETA DEXTRO ARABINOSE; ANTISENSE OLIGONUCLEOTIDE; ARABINOSE DERIVATIVE; CARBOHYDRATE DERIVATIVE; COMPLEMENTARY RNA; OLIGOMER; PHOSPHOROTHIOIC ACID DERIVATIVE; RIBONUCLEASE H; THROMBOCYTE ACTIVATING FACTOR; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN RECEPTOR; VASCULOTROPIN RECEPTOR 2; ANTISENSE OLIGODEOXYNUCLEOTIDE; ARABINONUCLEOSIDE; ENDOTHELIAL CELL GROWTH FACTOR; LYMPHOKINE; SIGNAL PEPTIDE; VASCULOTROPIN A;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; ENDOTHELIUM CELL; ENZYME ACTIVITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; PROTEIN SYNTHESIS INHIBITION; RNA BINDING; THROMBOCYTE ACTIVATION; ANIMAL; AORTA; BIOSYNTHESIS; CATTLE; CELL CULTURE; CELL DIVISION; CHEMISTRY; CHEMOTAXIS; CYTOLOGY; DRUG ANTAGONISM; HUMAN; METABOLISM; PHOSPHORYLATION; SYNTHESIS; VASCULAR ENDOTHELIUM;

ANIMALS; AORTA; ARABINONUCLEOSIDES; CATTLE; CELL DIVISION; CELLS, CULTURED; CHEMOTAXIS; ENDOTHELIAL GROWTH FACTORS; ENDOTHELIUM, VASCULAR; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LYMPHOKINES; OLIGODEOXYRIBONUCLEOTIDES, ANTISENSE; PHOSPHORYLATION; PLATELET ACTIVATING FACTOR; RIBONUCLEASE H, CALF THYMUS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 1842833037     PISSN: 00084212     EISSN: None     Source Type: Journal    
DOI: 10.1139/y02-123     Document Type: Article

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