Increased expression and decreased activity of cytochrome P450 1A1 in a murine model of toluene diisocyanate-induced asthma

Archives of Toxicology

Volumn 76, Issue 11, 2002, Pages 621-627

  Haag, Muriel ^a   Leusink Muis, Thea ^b   Le Bouquin, Renaud ^a   Nijkamp, Frans P ^b   Lugnier, Alain ^a   Frossard, Nelly ^a   Folkerts, Gert ^b   Pons, Françoise ^a  

^a INSERM   (France)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Asthma; CYP1A1; Cytochrome P450; Lung; Toluene diisocyanate

Indexed keywords

CYTOCHROME P450 1A1; CYTOCHROME P450 2B; CYTOCHROME P450 2E1; CYTOCHROME P450 3A; ETHOXYRESORUFIN; MESSENGER RNA; TOLUENE DIISOCYANATE; 3 METHYLCHOLANTHRENE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTHMA; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; IN VITRO STUDY; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MODIFICATION; SKIN SENSITIZATION; WESTERN BLOTTING; ANIMAL; BAGG ALBINO MOUSE; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; ENZYMOLOGY; GENETICS; LIVER MICROSOME; MALE; METABOLISM;

ANIMALS; ASTHMA; CYTOCHROME P-450 CYP1A1; MALE; METHYLCHOLANTHRENE; MICE; MICE, INBRED BALB C; MICROSOMES, LIVER; RNA, MESSENGER; TOLUENE 2,4-DIISOCYANATE;

EID: 1842832486     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-002-0393-z     Document Type: Article

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