A novel cytotoxic C-methylated biflavone, taiwanhomoflavone-B from the twigs of Cephalotaxus wilsoniana

Chemical and Pharmaceutical Bulletin

Volumn 50, Issue 12, 2002, Pages 1607-1608

  Kuo, Yao Haur ^a,b   Hwang, Shy Yuan ^c   Kuo, Li Ming Yang ^a   Lee, Yi Ling ^a,b   Li, Shyh Yuan ^b   Shen, Ya Ching ^d  

^a NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE   (Taiwan)

^b CHINESE CULTURE UNIVERSITY   (Taiwan)

^c ENDEMIC SPECIES RESEARCH INSTITUTE   (Taiwan)

^d NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

Author keywords

6 C methylnaringenin; 7,4 ,7 tri O methylamentoflavone; Apigen 7 O glucoside; Cephalotaxus wilsoniana; Cytotoxicity; Kamepferol; Taiwanhomoflavone B

Indexed keywords

6 C METHYLNARINGENIN; 7,4',7'' TRI O METHYLAMENTOFLAVONE; ANTINEOPLASTIC AGENT; APIGENIN 7 O BETA GLUCOSIDE; CEPHALOTAXUS WILSONIANA EXTRACT; FLAVONE DERIVATIVE; PLANT EXTRACT; TAIWANHOMOFLAVONE B; UNCLASSIFIED DRUG; FLAVONOID; TAIWANHOMOFLAVONE-B;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CEPHALOTAXUS; CEPHALOTAXUS WILSONIANA; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE RESPONSE; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG ISOLATION; DRUG STRUCTURE; HUMAN; HUMAN CELL; METHYLATION; SPECTROSCOPY; CELL CULTURE; CELL SURVIVAL; CHEMICAL STRUCTURE; CHEMISTRY; ISOLATION AND PURIFICATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PLANT; STRUCTURE ACTIVITY RELATION;

CELL SURVIVAL; CEPHALOTAXUS; FLAVONOIDS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; METHYLATION; MOLECULAR STRUCTURE; PLANT SHOOTS; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 1842832398     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.50.1607     Document Type: Article

References (12)

1. Powell R. G., Weisleder D., Smith C. R., Jr., Wolff I. A., Tetrahedron Lett., 1969, 4081-4084 (1969).
2. Powell R. G., Weisleder D., Smith C. R., Jr., Rohwedder W. K., Tetrahedron Lett., 1970, 815-818 (1970).
3. Khan N. U., Ilyas M., Rahman W., Okigawa M., Kawano N., Phytochemistry, 10, 2541-2545 (1971).
4. Powell R. G., Mikolajczak K. L., Weisleder D., Smith C. R., Jr., Phytochemistry, 11, 3317-3320 (1972).
5. Sun N., Xue Z., Liang S., Huang L., Acta Pharmaceut. Sinica, 1, 39-43 (1979).
6. Qiu M., Lu B. M. X., Nie R., Acta Botanica Yunnanica, 1, 97-99 (1997).
7. Furukawa H., Itoigawa M., Haruna M., Jinno Y., Ito K., Lu S. T., Yakugaku Zasshi, 96, 1373-1377 (1976).
8. Kuo Y. H., Lin C. H., Hwang S. Y., Shen Y. C., Lee Y. L., Li S. Y., Chem. Pharm. Bull., 48, 440-441 (2000).
9. Markham K. R., Sheppard C., Geiger H., Phytochemistry, 26, 3335-3337 (1987).
10. Silva G. L., Chai H., Gupta M. P., Farnsworth N. R., Cordell G. A., Pezzuto J. M., Beecher C. W. W., Kinghorn A. D., Phytochemistry, 40, 129-134 (1995).
11. Sun N., Zhao Z., Chen R., Lin W., Zhou Y., Acta Pharmaceut. Sinica, 16, 233-234 (1981).
12. Kuo Y. H., Huang H. C., Kuo Yang L. M., Chen C. F., J. Org. Chem., 64, 7023-7027 (1999).