A stereoselective synthesis for the (5Z,9Z)-14-methyl-5,9-pentadecadienoic acid and its monounsaturated analog (Z)-14-methyl-9-pentadecenoic acid

Tetrahedron Letters

Volumn 45, Issue 19, 2004, Pages 3761-3763

  Carballeira, Néstor M ^a   Sanabria, David ^a   Ayala, Norma L ^a   Cruz, Clarisa ^a  

^a UNIVERSITY OF PUERTO RICO   (Puerto Rico)

Author keywords

Alkyne coupling; Fatty acids; Synthesis; Topoisomerase I

Indexed keywords

14 METHYL 5,9 PENTADECADIENOIC ACID; 14 METHYL 9 PENTADECENOIC ACID; ALKYNE; DECANOIC ACID DERIVATIVE; DNA TOPOISOMERASE; FATTY ACID DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG SYNTHESIS; FATTY ACID ANALYSIS; STEREOCHEMISTRY;

EID: 1842828944     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2004.03.078     Document Type: Article

References (8)

1. Carballeira N.M., Reyes E.D., Sostre A., Rodríguez A.D., Rodríguez J.L., González F.A. J. Nat. Prod. 60:1997;502.
2. Reyes E.D., Carballeira N.M. Synthesis. 1997;1195.
3. Suzuki K., Shono F., Kai H., Uno T., Uyeda M. J. Enzyme Inhib. 15:2000;357.
4. Gillan F.T., Johns R.B., Verheyen T.V., Volkman J.K., Bavor H. J. Appl. Environ. Microbiol. 41:1981;849.
5. Lee H.K., Lee D.S., Kim J., Kim J.S., Im K.S., Jung J.H. Arch. Pharm. Res. 21:1998;729.
6. The spectral data for acid 1 was reported in Ref. 2 above.
7. +, 10), 236 (5), 193 (3), 181 (9), 173 (2), 163 (7), 162 (2), 151 (4), 137 (6), 133 (3), 125 (6), 123 (9), 111 (15), 109 (10), 97 (28), 84 (27), 83 (40), 81 (25), 69 (99), 67 (32), 57 (53), 55 (100).
8. Nemoto T., Yoshino G., Ojika M., Sakagami Y. Tetrahedron. 53:1997;16699.