Criteria for risk assessment of botanical food supplements

Toxicology Letters

Volumn 149, Issue 1-3, 2004, Pages 187-195

  Walker, R ^a  

^a UNIVERSITY OF SURREY   (United Kingdom)

Author keywords

Botanical supplements; Decision tree; Guidelines; Risk assessment

Indexed keywords

ESSENTIAL OIL; FOOD ADDITIVE; HERBACEOUS AGENT; HYPERFORIN; HYPERICIN; LIMONENE; PHYTOSTEROL; STEVIOSIDE;

ACUTE TOXICITY; ANTIOXIDANT ACTIVITY; CHRONIC TOXICITY; CITRUS FRUIT; CONFERENCE PAPER; DIET SUPPLEMENTATION; ENZYME INDUCTION; ENZYME INHIBITION; EXPOSURE; FOOD COMPOSITION; FOOD CONTAMINATION; FOOD INTAKE; FRACTIONATION; HERB; HUMAN; HYPERICUM PERFORATUM; NONHUMAN; NUTRITIONAL REQUIREMENT; NUTRITIONAL STATUS; PRIORITY JOURNAL; RISK ASSESSMENT; RISK MANAGEMENT; SPICE; STEVIA; TOXICITY TESTING; TOXICOKINETICS;

ANIMALS; DIETARY SUPPLEMENTS; HUMANS; PLANTS, MEDICINAL; RISK ASSESSMENT;

EID: 1842817412     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2004.03.001     Document Type: Conference Paper

References (9)

1. Betz J.M., Eppley R.M., Taylor W.C., Andrzejewski D. Determination of pyrrolizidine alkaloids in commercial comfrey products (Symphytum sp.). J. Pharmacol. Sci. 83(5):1994;649-653.
2. Chambolle M. Assessment of extreme levels of chronic food intakes. Reg. Toxicol. Pharmacol. 30:1999;S13-S18.
3. Ernst E. The risk-benefit profile of commonly used herbal therapies: Ginkgo, St. John's Wort, Ginseng, Echinacea, Saw Palmetto, and Kava. Ann. Int. Med. 136:2002;42-53.
4. European Commission, 1997a. Recommendations concerning the scientific aspects of information necessary to support applications for the placing on the market of novel foods and novel ingredients. Official J. Eur. Commun. L253/1-L253/36.
5. Harkey M.R., Henderson G.L., Gershwin M.E., Stern J.S., Hackman R.M. Variability in commercial ginseng products: an analysis of 25 preparations. Am. J. Clin. Nutr. 76:2001;1101-1106.
6. Nortier J.L., Muniz Martinez M.-C., Schmeiser H.H., Arlt V.M., Bieler C.A., Petein M., Depierreux M.F., De Paw L., Abramowicz D., Vereerstraeten P., Vanherwegheim J.-L. Urothelial carcinoma associated with the use of a Chinese herb (Aristolochia fanghi). New Engl. J. Med. 342:2000;1686-1692.
7. Renwick A.G., Lazarus N.R. Human variability and noncancer risk assessment - an analysis of the default uncertainty factor. Reg. Toxicol. Pharmacol. 27:1998;3-20.
8. WHO (World Health organization), 1987. Principles for the safety assessment of food additives and contaminants in food. IPCS Environmental Health Criteria 70. World Health Organization, Geneva.
9. WHO (World Health organization), 1990. Principles for the toxicological assessment of pesticide residues in food. IPCS Environmental Health Criteria 104. World Health Organization, Geneva.