MK-801 prevents the increased NMDA-NR1 and NR2B subunits mRNA expression observed in the hippocampus of rats tolerant to diazepam

Brain Research

Volumn 1008, Issue 1, 2004, Pages 54-60

  Almirón, Romina S ^a   Pérez, Mariela F ^a   Ramírez, Oscar A ^a  

^a UNIVERSIDAD NACIONAL DE CÓRDOBA   (Argentina)

Author keywords

Diazepam; Drugs of abuse: alcohol, barbiturates and benzodiazepines; Glutamate receptor subunit; Hippocampal synaptic plasticity; MK 801; Neural basis of behavior; Tolerance

Indexed keywords

DIAZEPAM; DIZOCILPINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PROTEIN SUBUNIT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONDITIONING; CONTROLLED STUDY; DRUG TOLERANCE; GLUTAMATERGIC TRANSMISSION; HIPPOCAMPUS; LOCOMOTION; MALE; NERVE CELL PLASTICITY; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; PROPHYLAXIS; PROTEIN EXPRESSION; RAT;

ANALYSIS OF VARIANCE; ANIMALS; BEHAVIOR, ANIMAL; CELL COUNT; DIAZEPAM; DIZOCILPINE MALEATE; DRUG INTERACTIONS; DRUG TOLERANCE; ELECTRIC STIMULATION; ELECTROPHYSIOLOGY; EVOKED POTENTIALS; EXCITATORY AMINO ACID ANTAGONISTS; GABA MODULATORS; GENE EXPRESSION REGULATION; HIPPOCAMPUS; IN SITU HYBRIDIZATION; LONG-TERM POTENTIATION; MALE; MOTOR ACTIVITY; RANDOM ALLOCATION; RATS; RATS, WISTAR; RECEPTORS, N-METHYL-D-ASPARTATE; RNA, MESSENGER;

EID: 1842815264     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2004.01.080     Document Type: Article

References (35)

1. Andrés M.E., Gysling K., Araneda S., Venegas A., Bustos G. NMDA-NR1 receptor subunit mRNA expression in rat brain after 6-OH-Dopamine induced lesions: a non-isotopic in situ hybridization study. J. Neurosci. Res. 46:1996;375-384.
2. Cook L., Sepinwall J. Behavioral analysis of the effects and mechanisms of action of benzodiazepines. Costa E., Greengard P. Advances in Biochemical Psychopharmacology. Mechanism of Action of Benzodiazepines. vol. 14:1975;Raven Press, New York.
3. De Montis M.G., Devoto P., Meloni D., Gambarana C., Giorgi G., Tagliamonte A. NMDA receptor inhibition prevents tolerance to cocaine. Pharmacol. Biochem. Behav. 42:1992;179-182.
4. Douglas R.M., Goddard G.V. Long-term-potentiation of the perforant path-granule cell synapse in the rat hippocampus. Brain Res. 86:1975;205-215.
5. File S.E. Rapid development of tolerance to the sedative effects of lorazepam and triazolam in rats. Psychopharmacology (Berlin). 73:1981;240-245.
6. File S.E. Tolerance to the behavioral actions of benzodazepines. Neurosci. Biobehav. Rev. 9:1985;113-121.
7. File S.E., Fernandez C. Dizocilpine prevents the development of tolerance to the sedative effects of diazepam in rats. Pharmacol. Biochem. Behav. 47:1994;823-826.
8. Harris E.W., Ganong A.H., Cotman C.W. Long-term potentiation in the hippocampus involves activation of N-methyl-D-aspartate receptors. Brain Res. 323:1984;132-137.
9. Khanna J.M., Mihic S.J., Weiner J., Shah G., Wu P.H., Kalant H. Effect of NMDA receptor antagonists on rapid tolerance to ethanol. Eur. J. Pharmacol. 230:1993;23-31.
10. Lomo T. Potentiation of monosynaptic EPSPs in the perforant path-dentate granule cells synapse. Exp. Brain Res. 12:1971;46-67.
11. Marek P., Ben-Eliyahu S., Gold M., Liebeskind J.C. Excitatory amino acid antagonists (kinurenic acid and MK-801) attenuate the development of morphine tolerance in rat. Brain Res. 547:1991;77-81.
12. Marín R.H., Salvatierra N.A., Ramirez O.A. Rapid tolerance to benzodiazepine modifies rat hippocampal synaptic plasticity. Neurosci. Lett. 215:1996;149-152.
13. Marín R.H., Pérez M.F., Duero D.G., Ramírez O.A. Pre-exposition to drug administration context blocks the development to tolerance to sedative effects of diazepam. Pharmacol. Biochem. Behav. 64:1999;473-477.
14. Monyer H., Spregel R., Schoepfer R., Herb A., Higuchi M., Lomeli H., Burnasher N., Sakmann B., Seeburg P.H. Heteromeric NMDA receptors: molecular and functional distinction of subtypes. Science. 256:1992;1217-1221.
15. Moriyoshi K., Masu M., Ishii T., Shigemoto R., Mizuno N., Nakanishi S. Molecular cloning and characterization of the rat NMDA receptors. Nature. 354:1991;31-37.
16. Morris R.G.M., Anderson E., Lynch G.S., Baudry M. Selective impairment of learning and blockade of long-term potentiation by N-methyl-D-aspartate receptor antagonist APV. Nature. 319:1986;774-776.
17. Nestler E.J. Molecular basis of addictive states. The Neuroscientist. 1(4):1995;212-220.
18. Nestler E.J. Molecular basis of long-term plasticity underlying addiction. Nat. Rev., Neurosci. 2(2):2001;119-128.
19. Nestler E.J. Common molecular and cellular substrates of addiction and memory. Neurobiol. Learn. Mem. 78(3):2002;637-647.
20. Pérez M.F., Maglio L.E., Marchesini G.R., Molina J.C., Ramírez O.A. Environmental changes modify the expression of diazepam withdrawal. Behav. Brain Res. 136:2002;75-81.
21. Pérez M.F., Almirón R.S., Ramírez O.A. NMDA-NR1 and -NR2B subunits mRNA expression in the hippocampus of rats tolerant to diazepam. Behav. Brain Res. 144:2003;119-124.
22. Robinson G.B., Reed G.D. Effect of MK-801 on the induction and subsequent decay of long-term potentiation in the unanesthetized rabbit hippocampal dentate gyrus. Brain Res. 569:1992;78-85.
23. Rosenberg H.C., Chiu T.H. Time course for development of benzodiazepine tolerance and physical dependence. Neurosci. Biobehav. Rev. 9:1985;123-131.
24. Rosenblum K., Dudai Y., Ritcher-Levin G. Long-term potentiation increases tyrosine phosphorylation in the N-methyl-D-aspartate receptor subunit 2B in rat dentate gyrus in vivo. Proc. Natl. Acad. Sci. U. S. A. 93:1996;10457-10460.
25. Rostas J.A., Brent V.A., Voss K., Errington C., Bliss T.V., Gurd J.W. Enhanced tyrosine phosphorylation of the 2B subunit of the N-methyl-D-aspartate receptor in long-term potentiation. Proc. Natl. Acad. Sci. U. S. A. 93:1996;10452-10456.
26. Siegel S. Pharmacological conditioning and drug effects. Goudie A.I., Emmett-Oglesby M.W. Psychoactive Drugs: Tolerance and Sensitization. 1989;115-169 Humana Press, New Jersey.
27. Steppuhn K.G., Turski L. Diazepam dependence prevented by glutamate antagonists. Proc. Natl. Acad. Sci. U. S. A. 90:1993;6889-6993.
28. Tayler T.J., Discena P. Long-term potentiation as a candidate mnemonic device. Brain Res. Rev. 7:1984;15-28.
29. Tayler T.J., Di Scenna P. Long-term potentiation. Annu. Rev. Neurosci. 10:1987;131-161.
30. Thompson A.M., Gosnell B.A., Wagner J.J. Enhancement of long-term potentiation in the rat hippocampus following cocaine exposure. Neuropharmacology. 42(8):2002;1039-1042.
31. Trujillo K.A., Akil H. Inhibition of morphine tolerance by the NMDA receptor antagonist MK-801. Science. 251:1991;85-87.
32. Winder D.G., Egli R.E., Schramm N.L., Matthews R.T. Synaptic plasticity in drug reward circuitry. Curr. Mol. Med. 2(7):2002;667-676.
33. Woodroff G.N., Foster A.C., Gill R., Kemp J.A., Wong E.H.F., Iversen L.L. The interaction between MK-801 and receptors for N-methyl-D-aspartate. Neuropharmacology. 26:1987;903-909.
34. Wu P.H., Mihic S.J., Liu J.F., Le A.D., Kalant H. Blockade of chronic tolerance to ethanol by the NMDA antagonist, (+)-MK-801. Eur. J. Pharmacol. 231:1993;157-164.
35. Ya-ping T., Eiji S., Dube G., Rampon C., Kerchner G., Min Z., Guosong L., Tsien J. Genetic enhancement of learning and memory in mice. Nature. 401:1999;63-69.