Functional Analysis of the Interface Regions Involved in Interactions between the Central Cytoplasmic Loop and the C-terminal Tail of Adenylyl Cyclase

Journal of Biological Chemistry

Volumn 279, Issue 14, 2004, Pages 13925-13933

  Yoo, Barney ^a   Iyengar, Ravi ^a   Chen, Yibang ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BIOLOGICAL MEMBRANES; CATALYSIS; CRYSTAL STRUCTURE;

CYTOPLASMIC LOOPS; PEPTIDES;

ENZYMES;

ADENYLATE CYCLASE; ADENYLATE CYCLASE 2; ADENYLATE CYCLASE 6; FORSKOLIN; MANGANESE; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME ANALYSIS; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION;

ADENYLATE CYCLASE; AMINO ACID SEQUENCE; ANIMALS; CYTOPLASM; ENZYME ACTIVATION; FORSKOLIN; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; MAMMALS; MANGANESE; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PROTEIN STRUCTURE, TERTIARY;

ANIMALIA; INSECTA; MAMMALIA;

EID: 1842790972     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M314334200     Document Type: Article

References (20)

1. Hanoune, J., and Defer, N. (2001) Ann. Rev. Pharmacol. Toxicol 41, 145-174
2. Smit, M. J., and Iyengar, R. (1998) Adv. Second Messenger Phosphoprotein Res. 32, 1-21
3. Tesmer, J. J. G., Sunahara, R., Gilman, A. G., and Sprang, S. R. (1997) Science 278, 1907-1916
4. Tang, W. J., Stancel, M., and Gilman, A. G. (1995) Biochemistry 34, 14563-14572
5. Yan, S.-Z., Huang, Z.-H., Rao, V.-D., Hurley, J.-H., and Tang, W.-J. (1997) J. Biol. Chem. 272, 18849-18854
6. Hatley, M. E., Benton, B. K., Xu, J., Manfredi, J. P., Gilman, A. G., and Sunahara, R. K. (2000) J. Biol. Chem. 275, 38626-38632
7. Graziano, M. P., Freissmuth, M., and Gliman, A. G. (1991) Methods Enzymol. 195, 192-215
8. Pieroni, J. P., Harry, A., Chen, J., Jacobowitz, O., Magnusson, R. P., and Iyengar, R. (1995) J. Biol. Chem. 270, 21368-21373
9. Harry, A., Chen, Y., Magnusson, R. P., Iyengar, R., and Weng, G. (1997) J. Biol. Chem. 272, 19017-19021
10. Chen, Y., Yoo, B., Lee, J. B., Weng, G., and Iyengar R. (2001) J. Biol. Chem. 276, 45751-45754
11. Tang, W. J., and Gilman, A. G. (1995) Science 268, 1769-1772
12. Dessauer, C. W., and Gilman, A. G. (1997) J. Biol. Chem. 272, 27787-27795
13. Dessauer, C. W., Scully, T. T., and Gilman, A. G. (1997) J. Biol. Chem. 272, 27772-27777
14. Tesmer, J. G. J., Sunahara, R., Johnson, R. A., Gosselin, G., Gilman, A. G., and Sprang, S. R. (1999) Science 285, 756-760
15. Tesmer, J. G. J., and Sprang, S. R. (1998) Curr. Opin. Struct. Biol. 8, 713-719
16. Skiba, N. P., and Hamm, H. E. (1998) Nat. Struct. Biol. 5, 88-92
17. Wittpoth, C., Scholich, K., Yigzaw, Y., Stringfield, T. M., and Patel, T. B. (1999) Proc. Natl. Acad. Sci. 96, 9551-9556
18. Parent, C. A., Borleis, J., and Devereotes, P. N. (2002) J. Biol. Chem. 277, 1354-1360
19. Dessauer, C. W., Chen-Goodspeed, M., and Chen, J. (2002) J. Biol. Chem. 277, 28823-28829
20. Hildebrandt, J. D., and Birnbaumer, L. (1983) J. Biol. Chem. 258, 13141-13147