Transvascular passage of macromolecules into the peritoneal cavity of normo- and hypothermic rats in vivo: Active or passive transport?

Journal of Vascular Research

Volumn 41, Issue 2, 2004, Pages 123-130

  Rosengren, Bert Inge ^a,b   Carlsson, Ola ^a   Venturoli, Daniele ^a   Al Rayyes, Osama ^a   Rippe, Bengt ^a  

^a LUND UNIVERSITY   (Sweden)

^b LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Capillary; Caveolae; Peritoneal dialysis; Permeability; Pores; Protein; Transcytosis

Indexed keywords

EDETATE CHROMIUM CR 51; GLUCOSE; HUMAN ALBUMIN; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; LOW DENSITY LIPOPROTEIN; RADIOISOTOPE;

ACTIVE TRANSPORT; ANIMAL EXPERIMENT; ARTICLE; BLOOD; BLOOD FLOW; BODY TEMPERATURE; CONTROLLED STUDY; COOLING; DIALYSATE; IN VIVO STUDY; INDUCED HYPOTHERMIA; ISOTOPE LABELING; MACROMOLECULE; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PASSIVE TRANSPORT; PERITONEAL CAVITY; PERITONEAL DIALYSIS; PERITONEAL FLUID; PERMEABILITY; PLASMA VISCOSITY; PRIORITY JOURNAL; PROTEIN TRANSPORT; RAT; SOLUTE; TRANSCYTOSIS; TRANSPORT KINETICS;

ALBUMINS; ANIMALS; BIOLOGICAL TRANSPORT, ACTIVE; BLOOD PRESSURE; CAPILLARY PERMEABILITY; CAVEOLAE; CHOLESTEROL, LDL; HEART RATE; HYPOTHERMIA; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; MACROMOLECULAR SUBSTANCES; MALE; MOLECULAR WEIGHT; PERITONEAL CAVITY; PERITONEAL DIALYSIS; RATS; RATS, WISTAR; REGIONAL BLOOD FLOW;

EID: 1842729355     PISSN: 10181172     EISSN: None     Source Type: Journal    
DOI: 10.1159/000077131     Document Type: Article

References (38)

1. Michel CC, Curry FE: Microvascular permeability. Physiol Rev 1999;79:703-761.
2. Rippe B, Rosengren BI, Carlsson O, Venturoli D: Transendothelial transport: The vesicle controversy. J Vasc Res 2002;39:375-390.
3. Palade GE: Transport in quanta across the endothelium of blood capillaries. Anat Rec 1960;136:254.
4. Predescu D, Horvat R, Predescu S, Palade GE: Transcytosis in the continuous endothelium of the myocardial microvasculature is inhibited by N-ethylmaleimide. Proc Natl Acad Sci USA 1994;91:3014-3018.
5. Predescu SA, Predescu DN, Palade GE: Plasmalemmal vesicles function as transcytotic carriers for small proteins in the continuous endothelium. Am J Physiol 1997;272:H937-H949.
6. Schnitzer JE, Allard J, Oh P: NEM inhibits transcytosis, endocytosis, and capillary permeability: Implication of caveolae fusion in endothelia. Am J Physiol 1995;268:H48-H55.
7. Schnitzer JE, Oh P, Pinney E, Allard J: Filipin-sensitive caveolae-mediated transport in endothelium: Reduced transcytosis, scavenger endocytosis, and capillary permeability of select macromolecules. J Cell Biol 1994;127:1217-1232.
8. Bundgaard M: The three-dimensional organization of tight junctions in a capillary endothelium revealed by serial-section electron microscopy. J Ultrastruct Res 1984;88:1-17.
9. Frokjaer-Jensen J: Three-dimensional organization of plasmalemmal vesicles in endothelial cells. An analysis by serial sectioning of frog mesenteric capillaries. J Ultrastruct Res 1980;73:9-20.
10. Rippe B, Kamiya A, Folkow B: Transcapillary passage of albumin, effects of tissue cooling and of increases in filtration and plasma colloid osmotic pressure. Acta Physiol Scand 1979;105:171-187.
11. Rutledge JC: Temperature and hydrostatic pressure-dependent pathways of low-density lipoprotein transport across microvascular barrier. Am J Physiol 1992;262:H234-H245.
12. Rutledge JC, Curry FE, Blanche P, Krauss RM: Solvent drag of LDL across mammalian endothelial barriers with increased permeability. Am J Physiol 1995;268:H1982-H1991.
13. Predescu D, Palade GE: Plasmalemmal vesicles represent the large pore system of continuous microvascular endothelium. Am J Physiol 1993;265:H725-H733.
14. Predescu D, Predescu S, McQuistan T, Palade GE: Transcytosis of alpha1-acidic glycoprotein in the continuous microvascular endothelium. Proc Natl Acad Sci USA 1998;95:6175-6180.
15. Rippe B, Taylor A: NEM and filipin increase albumin transport in lung microvessels. Am J Physiol Heart Circ Physiol 2001;280:H34-H41.
16. Carlsson O, Rosengren BI, Rippe B: Transcytosis inhibitor N-ethylmaleimide increases microvascular permeability in rat muscle. Am J Physiol Heart Circ Physiol 2001;281:H1728-H1733.
17. Rosengren BI, Al Rayyes O, Rippe B: Transendothelial transport of low-density lipoprotein and albumin across the rat peritoneum in vivo: Effects of the transcytosis inhibitors NEM and filipin. J Vasc Res 2002;39:230-237.
18. Ogawa K, Imai M, Ogawa T, Tsukamoto Y, Sasaki F: Caveolar and intercellular channels provide major transport pathways of macromolecules across vascular endothelial cells. Anat Rec 2001;264:32-42.
19. Rippe B, Rosengren BI, Venturoli D: The peritoneal microcirculation in peritoneal dialysis. Microcirculation 2001;8:303-320.
20. Zakaria ER, Rippe B: Intraperitoneal fluid volume changes during peritoneal dialysis in the rat: Indicator dilution vs. volumetric measurements. Blood Purif 1995;13:255-270.
21. Havel RJ, Eder HA, Bragdon JH: The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum. J Clin Invest 1955;34:1345-1353.
22. McFarlane AS: Efficient trace-labelling of proteins with iodine. Nature 1958;182:53.
23. Carlsson O, Nielsen S, Zakaria el-R, Rippe B: In vivo inhibition of transcellular water channels (aquaporin-1) during acute peritoneal dialysis in rats. Am J Physiol 1996;271:H2254-H2262.
24. Carlsson O, Rosengren BI, Rippe B: Effects of peritoneal hyaluronidase treatment on transperitoneal solute and fluid transport in the rat. Acta Physiol Scand 2000;168:371-376.
25. Rippe B, Krediet RT: Peritoneal physiology -Transport of solutes; in Gokal R, Nolph KD (eds): The Textbook of Peritoneal Dialysis. Dordrecht, Kluwer Academic Publishers, 1994, vol 1, pp 69-113.
26. Tveita T, Ytrehus K, Skandfer M, Oian P, Helset E, Myhre ES, Larsen TS: Changes in blood flow distribution and capillary function after deep hypothermia in rat. Can J Physiol Pharmacol 1996;74:376-381.
27. Weast RC: Handbook of Chemistry and Physics, ed 58. Cleveland, CRC Press, 1978.
28. Rosengren BI, Rippe B: Blood flow limitation in vivo of small solute transfer during peritoneal dialysis in rats. J Am Soc Nephrol 2003;14:1599-1604.
29. Renström E, Eliasson L, Bokvist K, Rorsman P: Cooling inhibits exocytosis in single mouse pancreatic B-cells by suppression of granule mobilization. J Physiol 1996;494/1:41-52.
30. Rippe B, Grega GJ: Effects of isoprenaline and cooling on histamine induced changes of capillary permeability in the rat hindquarter vascular bed. Acta Physiol Scand 1978;103:252-262.
31. Haraldsson B, Zackrisson U, Rippe B: Calcium dependence of histamine-induced increases in capillary permeability in isolated perfused rat hindquarters. Acta Physiol Scand 1986;128:247-258.
32. Bos HJ, Meyer F, de Veld JC, Beelen RH: Peritoneal dialysis fluid induces change of mononuclear phagocyte proportions. Kidney Int 1989;36:20-26.
33. Bos HJ, Struijk DG, Tuk CW, de Veld JC, Helmerhorst TJ, Hoefsmit EC, Arisz L, Beelen RH: Peritoneal dialysis induces a local sterile inflammatory state and the mesothelial cells in the effluent are related to the bacterial peritonitis incidence. Nephron 1991;59:508-509.
34. Drab M, Verkade P, Elger M, Kasper M, Lohn M, Lauterbach B, Menne J, Lindschau C, Mende F, Luft FC, Schedl A, Haller H, Kurzchalia TV: Loss of caveolae, vascular dysfunction, and pulmonary defects in caveolin-1 genedisrupted mice. Science 2001;293:2449-2452.
35. Kagan A, Bar-Khayim Y, Schafer Z, Fainaru M: Kinetics of peritoneal protein loss during CAPD. II. Lipoprotein leakage and its impact on plasma lipid levels. Kidney Int 1990;37:980-990.
36. Vermeer BJ, Reman FC, van Gent CM: The determination of lipids and proteins in suction blister fluid. J Invest Dermatol 1979;73:303-305.
37. Haraldsson B, Rippe B: Orosomucoid as one of the serum components contributing to normal capillary permselectivity in rat skeletal muscle. Acta Physiol Scand 1987;129:127-135.
38. Rosengren B-I, Venturoli D, Carlsson O, Rayyes OA, Rippe B: Passage of low-density lipoprotein (LDL), albumin and Cr-EDTA across the peritoneum in rats. Effects of hypothermia. Perit Dial Int 2001;21:S18.