Betulinic acid and its derivatives as anti-angiogenic agents

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 9, 2004, Pages 2181-2184

  Mukherjee, Rama ^a   Jaggi, Manu ^a   Rajendran, Praveen ^a   Siddiqui, Mohammad J A ^a   Srivastava, Sanjay K ^a   Vardhan, Anand ^a   Burman, Anand C ^a  

^a DABUR RESEARCH FOUNDATION   (India)

Author keywords

[No Author keywords available]

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ANGIOGENESIS INHIBITOR; BETULIC ACID; MATRIGEL;

ANTIANGIOGENIC ACTIVITY; ARTICLE; CELL ASSAY; CELL LINE; CONTROLLED STUDY; CYTOTOXICITY; DRUG POTENCY; DRUG SPECIFICITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENDOTHELIUM CELL; FEMALE; HUMAN; HUMAN CELL; IC 50; MALE; STRUCTURE ACTIVITY RELATION; TUMOR CELL LINE;

ANGIOGENESIS INHIBITORS; CELL LINE, TUMOR; HUMANS; STRUCTURE-ACTIVITY RELATIONSHIP; TRITERPENES;

EID: 1842690141     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.02.044     Document Type: Article

References (12)

1. Anderson, B.M.; Musser, H.J. WO 95/04526
2. Cichewicz R.H., Kouzi S.A. Med. Res. Rev. 24:2004;90.
3. Pisha E., Chai H., Lee I.S., Chagwedera T.E., Farnsworth N.R., Cordell G.A., Beecher C.W.W., Fong H.H.S., Kinghorn A.D., Brown D.M., Wani M.C., Wall M.E., Hieken T.J., Das Gupta T.K., Pezzuto J.M. Nat. Med. 1:1995;1046.
4. Steiner R. EXS. 61:1992;449.
5. Dordunoo S.K., Jackson J.K., Arsenault A.L., Oktaba A.M., Hunter W.L., Burt H.M. Cancer Chemother. Pharmacol. 36:1995;279.
6. Burt H.M., Jackson J.K., Bains S.K., Liggins R.T., Oktaba A.M., Arsenault A.L., Hunter W.L. Cancer Lett. 88:1995;73.
7. Ramadoss, S.; Jaggi, M.; Siddiqui, M. J. A.; Khanna, A. B. U.S. Patent 6,048,847, 2000
8. Ramadoss, S.; Jaggi, M.; Siddiqui, M. J. A.; Khanna, A. B. U.S. Patent 6,214,814, 2001
9. Jaggi, M.; Ramadoss, S.; Rajendran, P.; Siddiqui, M. J. A. U.S. Patent 6,228,850, 2001
10. Folkman J. Antiangiogenic therapy. Vincent T.D. Jr., Hellman S., Steven R. Cancer: Principles & Practice of Oncology. 5th ed. 1997;3075-3085 Lippincott-Raven, Philadelphia.
11. Mosmann T. J. Immunol. Meth. 65:1983;55.
12. Shinji S., Yoshiaki S., Hiroshi S. Biol. Pharm. Bull. 20:1997;1131.