메뉴 건너뛰기




Volumn 4, Issue 2, 2004, Pages 189-195

Epirubicin as adjuvant therapy in breast cancer

Author keywords

Adjuvant chemotherapy; Anthracyclines; Early breast cancer; Epirubicin; Survival

Indexed keywords

ALKYLATING AGENT; ANTHRACYCLINE; CYCLOPHOSPHAMIDE; DAUNORUBICIN; DOXORUBICIN; DOXORUBICIN DERIVATIVE; EPIRUBICIN; FLUOROURACIL; METHOTREXATE;

EID: 1842689603     PISSN: 14737140     EISSN: None     Source Type: Journal    
DOI: 10.1586/14737140.4.2.189     Document Type: Review
Times cited : (12)

References (29)
  • 2
    • 0035884636 scopus 로고    scopus 로고
    • Meeting highlights: International Consensus Panel on the Treatment of Primary Breast Cancer
    • Goldhirsch A, Glick JH, Gelber RD et al. Meeting highlights: International Consensus Panel on the Treatment of Primary Breast Cancer. J. Clin. Oncol. 19, 3817-3827 (2001).
    • (2001) J. Clin. Oncol. , vol.19 , pp. 3817-3827
    • Goldhirsch, A.1    Glick, J.H.2    Gelber, R.D.3
  • 3
    • 0028909867 scopus 로고
    • Adjuvant cyclophosphamide, methotrexate and fluorouracil in node-positive breast cancer, the results of 20 years of follow-up
    • Bonadonna G, Valagussa P, Moliterni A et al. Adjuvant cyclophosphamide, methotrexate and fluorouracil in node-positive breast cancer, the results of 20 years of follow-up. N. Engl. J. Med. 332, 901-906 (1995).
    • (1995) N. Engl. J. Med. , vol.332 , pp. 901-906
    • Bonadonna, G.1    Valagussa, P.2    Moliterni, A.3
  • 4
    • 0032547564 scopus 로고    scopus 로고
    • Poly-chemotherapy for early breast cancer: An overview of the randomized trials
    • Early Breast Cancer Trialists' Collaborative Group (EBCTC)
    • Early Breast Cancer Trialists' Collaborative Group (EBCTC). Poly-chemotherapy for early breast cancer: An overview of the randomized trials. Lancet 352, 930-942 (1998).
    • (1998) Lancet , vol.352 , pp. 930-942
  • 5
    • 0027932577 scopus 로고
    • Multilevel therapeutic targeting by topoisomerase inhibitors
    • Smith PJ, Soues S. Multilevel therapeutic targeting by topoisomerase inhibitors. Br. J. Cancer 23, S47 (1994).
    • (1994) Br. J. Cancer , vol.23
    • Smith, P.J.1    Soues, S.2
  • 6
    • 0028284366 scopus 로고
    • Clinical pharmacokinetics of epirubicin
    • Robert J. Clinical pharmacokinetics of epirubicin. Clin. Pharmacokinet. 26, 428-438 (1994).
    • (1994) Clin. Pharmacokinet. , vol.26 , pp. 428-438
    • Robert, J.1
  • 7
    • 0023934166 scopus 로고
    • A prospective randomized Phase III trial comparing combination chemotherapy with cyclophosphamide, fluorouracil and either doxorubicin or epirubicin
    • French Epirubicin Study Group
    • French Epirubicin Study Group. A prospective randomized Phase III trial comparing combination chemotherapy with cyclophosphamide, fluorouracil and either doxorubicin or epirubicin. J. Clin. Oncol. 6, 679-688 (1988).
    • (1988) J. Clin. Oncol. , vol.6 , pp. 679-688
  • 8
    • 0023924386 scopus 로고
    • Phase III randomized study of fluorouracil, epirubicin and cyclophosphamide vs. fluorouracil, doxorubicin and cyclophosphamide in advanced breast cancer: An Italian multicenter trial
    • Italian Multicenter Breast Study with Epirubicin Group
    • Italian Multicenter Breast Study with Epirubicin Group. Phase III randomized study of fluorouracil, epirubicin and cyclophosphamide vs. fluorouracil, doxorubicin and cyclophosphamide in advanced breast cancer: an Italian multicenter trial. J. Clin. Oncol. 6, 976-982 (1988).
    • (1988) J. Clin. Oncol. , vol.6 , pp. 976-982
  • 9
    • 0024553598 scopus 로고
    • 5-Fluorouracil, adriamycin, cyclophosphamide (FAC) vs. 5-fluorouracil, epirubicin, cyclophosphamide (FEC) in metastatic breast cancer
    • Lopez M, Papaldo O, Di Lauro L et al. 5-Fluorouracil, adriamycin, cyclophosphamide (FAC) vs. 5-fluorouracil, epirubicin, cyclophosphamide (FEC) in metastatic breast cancer. Oncology 46, 1-5 (1989).
    • (1989) Oncology , vol.46 , pp. 1-5
    • Lopez, M.1    Papaldo, O.2    Di Lauro, L.3
  • 10
    • 0025274858 scopus 로고
    • Randomized clinical trial comparing mitoxantrone with epirubicin and with doxorubicin, each combined with cyclophosphamide in the first-line treatment of patients with metastatic breast cancer
    • Heidemann E, Steinke B, Harlapp J et al. Randomized clinical trial comparing mitoxantrone with epirubicin and with doxorubicin, each combined with cyclophosphamide in the first-line treatment of patients with metastatic breast cancer. Onkologie 13, 24-27 (1990).
    • (1990) Onkologie , vol.13 , pp. 24-27
    • Heidemann, E.1    Steinke, B.2    Harlapp, J.3
  • 11
    • 0027322924 scopus 로고
    • A comparison of doxorubicin, epirubicin and mitoxantrone as single agents in advanced breast carcinoma
    • Lawton PA, Spittle MF, Ostrowski MJ et al. A comparison of doxorubicin, epirubicin and mitoxantrone as single agents in advanced breast carcinoma. J. Clin. Oncol. 5, 80-44 (1993).
    • (1993) J. Clin. Oncol. , vol.5 , pp. 44-80
    • Lawton, P.A.1    Spittle, M.F.2    Ostrowski, M.J.3
  • 12
    • 0141475108 scopus 로고    scopus 로고
    • NEAT (National Epirubicin Adjuvant Trial) and SCTBG BR 9601 (Scottish Cancer Trials breast group) Phase III adjuvant breast trials show a significant relapse-free and overall survival advantage for sequential ECMF
    • (Abstract 13)
    • Poole CJ, Earl HM, Dunn JA et al. NEAT (National Epirubicin Adjuvant Trial) and SCTBG BR 9601 (Scottish Cancer Trials breast group) Phase III adjuvant breast trials show a significant relapse-free and overall survival advantage for sequential ECMF. Proc. Am. Soc. Clin. Oncol. 22, 4 (2003) (Abstract 13).
    • (2003) Proc. Am. Soc. Clin. Oncol. , vol.22 , pp. 4
    • Poole, C.J.1    Earl, H.M.2    Dunn, J.A.3
  • 13
    • 0030068274 scopus 로고    scopus 로고
    • Adjuvant cyclophosphamide, methotrexate and fluorouracil versus fluorouracil, epirubicin and cyclophosphamide chemotherapy in premenopausal women with axillary node-positive operable breast cancer: Results of a randomized trial
    • The International Collaborative Cancer Group
    • Coombes RC, Bliss JM, Wils J et al. Adjuvant cyclophosphamide, methotrexate and fluorouracil versus fluorouracil, epirubicin and cyclophosphamide chemotherapy in premenopausal women with axillary node-positive operable breast cancer: Results of a randomized trial. The International Collaborative Cancer Group. J. Clin. Oncol. 14, 35-45 (1996).
    • (1996) J. Clin. Oncol. , vol.14 , pp. 35-45
    • Coombes, R.C.1    Bliss, J.M.2    Wils, J.3
  • 14
    • 0031927983 scopus 로고    scopus 로고
    • Randomized trial of intensive cyclophosphamide, epirubicin and fluorouracil chemotherapy compared with cyclophosphamide, methotrexate and fluorouracil in premenopausal women with node-positive breast cancer
    • National Cancer Institute of Canada Clinical Trials Group
    • Levine MN, Bramwell VH, Pritchard KI et al. Randomized trial of intensive cyclophosphamide, epirubicin and fluorouracil chemotherapy compared with cyclophosphamide, methotrexate and fluorouracil in premenopausal women with node-positive breast cancer. National Cancer Institute of Canada Clinical Trials Group. J. Clin. Oncol. 16, 2651-2658 (1998).
    • (1998) J. Clin. Oncol. , vol.16 , pp. 2651-2658
    • Levine, M.N.1    Bramwell, V.H.2    Pritchard, K.I.3
  • 15
    • 0001003284 scopus 로고    scopus 로고
    • Adjuvant anthracycline in breast cancer. Improved outcome in premenopausal patients following substitution of methotrexate in the CMF combination with epirubicin
    • (Abstract 254)
    • Mouridsen HT, Andersen J, Andersson M et al. Adjuvant anthracycline in breast cancer. Improved outcome in premenopausal patients following substitution of methotrexate in the CMF combination with epirubicin. Proc. Am. Soc. Clin. Oncol. 18, 68a (1999) (Abstract 254).
    • (1999) Proc. Am. Soc. Clin. Oncol. , vol.18
    • Mouridsen, H.T.1    Andersen, J.2    Andersson, M.3
  • 16
    • 0035875815 scopus 로고    scopus 로고
    • Phase III trial comparing two dose levels of epirubicin combined with epirubicin, with cyclophosphamide, methotrexate and fluorouracil in node-positive breast cancer
    • Piccart MJ, Di Leo A, Beauduin M et al. Phase III trial comparing two dose levels of epirubicin combined with epirubicin, with cyclophosphamide, methotrexate and fluorouracil in node-positive breast cancer. J. Clin. Oncol. 19, 3103-3110 (2001).
    • (2001) J. Clin. Oncol. , vol.19 , pp. 3103-3110
    • Piccart, M.J.1    Di Leo, A.2    Beauduin, M.3
  • 17
    • 0035253733 scopus 로고    scopus 로고
    • Benefit of a high-dose epirubicin regimen in adjuvant chemotherapy for node-positive breast cancer patients with poor prognostic factors: 5-year follow-up results of French Adjuvant Study Group 05 randomized trial
    • French Adjuvant Study Group
    • French Adjuvant Study Group. Benefit of a high-dose epirubicin regimen in adjuvant chemotherapy for node-positive breast cancer patients with poor prognostic factors: 5-year follow-up results of French Adjuvant Study Group 05 randomized trial. J. Clin. Oncol. 19, 602-611 (2001).
    • (2001) J. Clin. Oncol. , vol.19 , pp. 602-611
  • 18
    • 0037440048 scopus 로고    scopus 로고
    • Randomized trial comparing six versus three cycles of epirubicin-based adjuvant chemotherapy in premenopausal, node positive breast cancer patients: 10 year follow-up results of the FASG 01 trial
    • Fumoleau P, Kerbrat P, Romestaing P et al. Randomized trial comparing six versus three cycles of epirubicin-based adjuvant chemotherapy in premenopausal, node positive breast cancer patients: 10 year follow-up results of the FASG 01 trial. J. Clin. Oncol. 21, 298-305 (2003).
    • (2003) J. Clin. Oncol. , vol.21 , pp. 298-305
    • Fumoleau, P.1    Kerbrat, P.2    Romestaing, P.3
  • 19
    • 0029966673 scopus 로고    scopus 로고
    • Dose-response relationship of epirubicin in the treatment of postmenopausal patients with metastatic breast cancer: A randomized study of epirubicin at four different dose levels performed by the Danish Breast Cancer Co-operative Group
    • Basholt L, Dalmark M, Gjedde SB et al. Dose-response relationship of epirubicin in the treatment of postmenopausal patients with metastatic breast cancer: A randomized study of epirubicin at four different dose levels performed by the Danish Breast Cancer Co-operative Group. J. Clin. Oncol. 4, 1146-1155 (1996).
    • (1996) J. Clin. Oncol. , vol.4 , pp. 1146-1155
    • Basholt, L.1    Dalmark, M.2    Gjedde, S.B.3
  • 20
    • 85039520355 scopus 로고    scopus 로고
    • Tolerability (toxicity, dose intensity and quality adjusted survival (QAS)) of ECMF versus CMF in the National Epirubicin Adjuvant Trial (NEAT) in moderate risk early breast cancer
    • on behalf of the NEAT Steering Committee
    • Earl HM, Poole CJ, Dunn JA et al. on behalf of the NEAT Steering Cominittee. Tolerability (toxicity, dose intensity and quality adjusted survival (QAS)) of ECMF versus CMF in the National Epirubicin Adjuvant Trial (NEAT) in moderate risk early breast cancer. Breast Cancer Res. Treat. 76(1), 647 (2002).
    • (2002) Breast Cancer Res. Treat. , vol.76 , Issue.1 , pp. 647
    • Earl, H.M.1    Poole, C.J.2    Dunn, J.A.3
  • 21
    • 0025365942 scopus 로고
    • Current status of epirubicin (Farmourubicin) in the treatment of solid tumors
    • Mouridsen HT, Alfthan C, Bastholt L et al. Current status of epirubicin (Farmourubicin) in the treatment of solid tumors. Acta Oncol. 29, 257-285 (1990).
    • (1990) Acta Oncol. , vol.29 , pp. 257-285
    • Mouridsen, H.T.1    Alfthan, C.2    Bastholt, L.3
  • 22
    • 0036175343 scopus 로고    scopus 로고
    • Multiple interference of anthracyclines with mitochondrial creatine kinases: Preferential damage of the cardiac isoenzyme and its implications for drug cardiotoxicity
    • Tokarska-Schlattner M, Wallimann T, Schlattner U. Multiple interference of anthracyclines with mitochondrial creatine kinases: preferential damage of the cardiac isoenzyme and its implications for drug cardiotoxicity. Mol. Pharm. 61(3), 516-523 (2002).
    • (2002) Mol. Pharm. , vol.61 , Issue.3 , pp. 516-523
    • Tokarska-Schlattner, M.1    Wallimann, T.2    Schlattner, U.3
  • 23
    • 0026686337 scopus 로고
    • Early assessment of a new anticancer drug analogue: Are the historical comparisons obsolete? The French experience with pirarubicin
    • Herait P, Poutignat N, Martyn M et al. Early assessment of a new anticancer drug analogue: Are the historical comparisons obsolete? The French experience with pirarubicin. Eur. J. Cancer 28A, 1670-1676 (1992).
    • (1992) Eur. J. Cancer , vol.28 A , pp. 1670-1676
    • Herait, P.1    Poutignat, N.2    Martyn, M.3
  • 24
    • 0031734394 scopus 로고    scopus 로고
    • Epirubicin cardiotoxicity: An analysis of 469 patients with metastatic breast cancer
    • Ryberg M, Nielsen D, Skovsgaard T et al. Epirubicin cardiotoxicity: An analysis of 469 patients with metastatic breast cancer. J. Clin. Oncol. 6(11), 3502-3508 (1998).
    • (1998) J. Clin. Oncol. , vol.6 , Issue.11 , pp. 3502-3508
    • Ryberg, M.1    Nielsen, D.2    Skovsgaard, T.3
  • 25
    • 0026697096 scopus 로고
    • Risk of leukemia after chemotherapy and radiation treatment for breast cancer
    • Curtis RE, Boice JD, Stovall M et al. Risk of leukemia after chemotherapy and radiation treatment for breast cancer. N. Engl. J. Med. 326, 1745-1751 (1992).
    • (1992) N. Engl. J. Med. , vol.326 , pp. 1745-1751
    • Curtis, R.E.1    Boice, J.D.2    Stovall, M.3
  • 26
    • 0035949708 scopus 로고    scopus 로고
    • Polymorphisms in glutathione S-transferase Pl is associated with susceptibility to chemotherapy-induced leukemia
    • Allan JM, Wild CP, Rollinson S et al. Polymorphisms in glutathione S-transferase Pl is associated with susceptibility to chemotherapy-induced leukemia. Proc. Natl Acad. Sci. US4 98(20), 11592-11597 (2001).
    • (2001) Proc. Natl. Acad. Sci. US4 , vol.98 , Issue.20 , pp. 11592-11597
    • Allan, J.M.1    Wild, C.P.2    Rollinson, S.3
  • 27
    • 0042914714 scopus 로고    scopus 로고
    • Risk of acute leukemia following epirubicin-based adjuvant chemotherapy: A report from the National Cancer Institute of Canada Clinical Trials Group
    • Crump M, Tu D, Shepherd L et al. Risk of acute leukemia following epirubicin-based adjuvant chemotherapy: A report from the National Cancer Institute of Canada Clinical Trials Group. J. Clin. Oncol. 21, 3066-3071 (2003).
    • (2003) J. Clin. Oncol. , vol.21 , pp. 3066-3071
    • Crump, M.1    Tu, D.2    Shepherd, L.3
  • 28
    • 0029782022 scopus 로고    scopus 로고
    • Treatment-related leukemia in breast cancer patients treated with fluorouracil-doxorubicin-cyclophosphamide combination adjuvant chemotherapy: The University of Texas MD Anderson Cancer Center Experience
    • Diamandidou E, Buzdar AU, Smith TL et al. Treatment-related leukemia in breast cancer patients treated with fluorouracil-doxorubicin-cyclophosphamide combination adjuvant chemotherapy: The University of Texas MD Anderson Cancer Center Experience. J. Clin. Oncol. 12, 2722-2730 (1996).
    • (1996) J. Clin. Oncol. , vol.12 , pp. 2722-2730
    • Diamandidou, E.1    Buzdar, A.U.2    Smith, T.L.3
  • 29
    • 0037900002 scopus 로고    scopus 로고
    • Second malignancies following chemothrapy: 6-year results from the Belgian randomized study comparing cyclophosphamide, methotrexate and 5-flourouracil (CMF) with anthracycline-based regimen in adjuvant treatment of node-positive breast cancer patients
    • Bernard-Marty C, Mano M, Paesmans M et al. Second malignancies following chemothrapy: 6-year results from the Belgian randomized study comparing cyclophosphamide, methotrexate and 5-flourouracil (CMF) with anthracycline-based regimen in adjuvant treatment of node-positive breast cancer patients. Ann. Oncol. 14, 693-698 (2003).
    • (2003) Ann. Oncol. , vol.14 , pp. 693-698
    • Bernard-Marty, C.1    Mano, M.2    Paesmans, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.