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Volumn 5, Issue 3, 2004, Pages 175-190

Nonsense-mediated mRNA decay: A comparative analysis different species

Author keywords

Cis acting destabilizing elements; Deadenylation and 3' to 5' mRNA decay; Decapping and 5' to 3' mRNA decay; Nonsense mediated mRNA decay; Premature termination of translation; RNA surveillance; Smg proteins; Upf proteins

Indexed keywords

CIS ACTING ELEMENT; MESSENGER RNA;

EID: 1842689543     PISSN: 13892029     EISSN: None     Source Type: Journal    
DOI: 10.2174/1389202043349453     Document Type: Review
Times cited : (36)

References (160)
  • 1
    • 0002650836 scopus 로고    scopus 로고
    • Nonsense-mediated RNA decay in mammalian cells, A splicing-dependent means to down-regulate the levels of mRNAs that prematurely terminate translation
    • eds. Sonenberg, N. Hershey, J.W.B. & Mathews, M.B. Cold Spring Harbor Press
    • Maquat, L.E., Nonsense-mediated RNA decay in mammalian cells, A splicing-dependent means to down-regulate the levels of mRNAs that prematurely terminate translation. Translational Control of Gene Expression, eds. Sonenberg, N. Hershey, J.W.B. & Mathews, M.B. Cold Spring Harbor Press. 2000, 849-868.
    • (2000) Translational Control of Gene Expression , pp. 849-868
    • Maquat, L.E.1
  • 2
    • 1842693361 scopus 로고    scopus 로고
    • Nonsense-mediated mRNA decay in mammalian cells, From pre-mRNA processing to mRNA translation and degradation
    • Edited by Lapointe J, Brakier-Gingras, L. Landes Bioscience, Austin, TX. 213-222
    • Maquat, L.E., Nonsense-mediated mRNA decay in mammalian cells, From pre-mRNA processing to mRNA translation and degradation. In, Translation Mechanisms. Edited by Lapointe, J, Brakier-Gingras, L. pp. 213-222. Landes Bioscience, Austin, TX., 2003, 213-222,
    • (2003) Translation Mechanisms , pp. 213-222
    • Maquat, L.E.1
  • 3
    • 0001211084 scopus 로고    scopus 로고
    • Destabilization of nonsense-containing transcripts in Saccharomyces cerevisiae
    • Edited by Sonenberg N, Hershey, J.W.B., Mathews, M.B. pp. 827-847. Cold Spring Harbor Press, New York
    • Peltz, S.W. and Jacobson A., Destabilization of nonsense-containing transcripts in Saccharomyces cerevisiae. In, Translational Control of Gene Expression Edited by Sonenberg, N, Hershey, J.W.B., Mathews, M.B. pp. 827-847. Cold Spring Harbor Press, New York, 2000, 827-847.
    • (2000) Translational Control of Gene Expression , pp. 827-847
    • Peltz, S.W.1    Jacobson, A.2
  • 4
    • 0032006979 scopus 로고    scopus 로고
    • Nonsense surveillance in lymphocytes?
    • Li, S. and Wilkinson M.F., Nonsense surveillance in lymphocytes? Immunity, 1998, 8, 135-141.
    • (1998) Immunity , vol.8 , pp. 135-141
    • Li, S.1    Wilkinson, M.F.2
  • 5
    • 0037382643 scopus 로고    scopus 로고
    • Looking at mRNA decay pathways through the window of molecular evolution
    • Culbertson, M.R. and Leeds, P.F., Looking at mRNA decay pathways through the window of molecular evolution. Curr. Opin. Genet. Dev., 2003, 13, 207-214.
    • (2003) Curr. Opin. Genet. Dev. , vol.13 , pp. 207-214
    • Culbertson, M.R.1    Leeds, P.F.2
  • 6
    • 0032837376 scopus 로고    scopus 로고
    • Nonsense-mediated mRNA decay in health and disease
    • Frischmeyer, P.A. and Dietz, H.C., Nonsense-mediated mRNA decay in health and disease. Hum. Mol. Genet., 1999, 8, 1893-1900.
    • (1999) Hum. Mol. Genet. , vol.8 , pp. 1893-1900
    • Frischmeyer, P.A.1    Dietz, H.C.2
  • 7
    • 0033525169 scopus 로고    scopus 로고
    • A perfect message, RNA surveillance and nonsense-mediated decay
    • Hentze, M.W. and Kulozik, A.E., A perfect message, RNA surveillance and nonsense-mediated decay. Cell, 1999, 96, 307-310.
    • (1999) Cell , vol.96 , pp. 307-310
    • Hentze, M.W.1    Kulozik, A.E.2
  • 8
    • 0033375911 scopus 로고    scopus 로고
    • Mechanisms of mRNA surveillance in eukaryotes
    • Hilleren, P. and Parker, R., Mechanisms of mRNA surveillance in eukaryotes. Annu Rev Genet 1999, 33, 229-260.
    • (1999) Annu. Rev. Genet. , vol.33 , pp. 229-260
    • Hilleren, P.1    Parker, R.2
  • 9
    • 0029026714 scopus 로고
    • The stability of Escherichia coli lacZ mRNA depends upon the simultancity of its synthesis and translation
    • Iost, I. and Dreyfus, M., The stability of Escherichia coli lacZ mRNA depends upon the simultancity of its synthesis and translation. EMBO J., 1995, 14, 3252-3261.
    • (1995) EMBO J. , vol.14 , pp. 3252-3261
    • Iost, I.1    Dreyfus, M.2
  • 10
    • 0029558248 scopus 로고
    • Transcribing of Escherichia colt genes with mutant T7 RNA polymerases, stability of lacZ mRNA inversely correlates with polymerase speed
    • Makarova, O.V., Makarov, E.M., Sousa, R. and Dreyfus, M., Transcribing of Escherichia colt genes with mutant T7 RNA polymerases, stability of lacZ mRNA inversely correlates with polymerase speed. Proc. Natl. Acad. Sci. USA, 1995, 92, 12250-12254.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 12250-12254
    • Makarova, O.V.1    Makarov, E.M.2    Sousa, R.3    Dreyfus, M.4
  • 11
    • 0025786141 scopus 로고
    • The product of the yeast UPF1 gene is required for rapid turnover of mRNAs containing a premature translational termination codon
    • Leeds, P., Peltz S.W., Jacobson, A. and Culbertson, M.R., The product of the yeast UPF1 gene is required for rapid turnover of mRNAs containing a premature translational termination codon. Genes Dev., 1991, 5, 2303-2314.
    • (1991) Genes Dev. , vol.5 , pp. 2303-2314
    • Leeds, P.1    Peltz, S.W.2    Jacobson, A.3    Culbertson, M.R.4
  • 12
    • 0027382460 scopus 로고
    • mRNA surveillance by the Caenorhabditis elegans smg genes
    • Pulak, R. and Anderson, P., mRNA surveillance by the Caenorhabditis elegans smg genes, Genes Dev., 1993, 7, 1885-1897.
    • (1993) Genes Dev. , vol.7 , pp. 1885-1897
    • Pulak, R.1    Anderson, P.2
  • 13
    • 0042025014 scopus 로고    scopus 로고
    • Nonsense-mediated mRNA decay in Drosophila, at the intersection of the yeast and mammalian pathways
    • Gatfield, D., Unterholzner, L., Ciccarelli, F.D., Bork, P. and Izaurralde, E., Nonsense-mediated mRNA decay in Drosophila, at the intersection of the yeast and mammalian pathways. EMBO J., 2003, 22, 3960-3970.
    • (2003) EMBO J. , vol.22 , pp. 3960-3970
    • Gatfield, D.1    Unterholzner, L.2    Ciccarelli, F.D.3    Bork, P.4    Izaurralde, E.5
  • 14
    • 0032544062 scopus 로고    scopus 로고
    • A mutated human homologue to yeast Upf1 protein has a dominant-negative effect on the decay of nonsense-containing mRNAs in mammalian cells
    • Sun, X., Perlick H.A., Dietz, H.C. and Maquat, L.E., A mutated human homologue to yeast Upf1 protein has a dominant-negative effect on the decay of nonsense-containing mRNAs in mammalian cells. Proc. Natl. Acad. Sci. USA, 1998, 95, 10009-10014.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 10009-10014
    • Sun, X.1    Perlick, H.A.2    Dietz, H.C.3    Maquat, L.E.4
  • 15
    • 0037064145 scopus 로고    scopus 로고
    • Separable roles for rent1/hUpf1 in altered splicing and decay of nonsense transcripts
    • Mendell, J.T., ap Rhys, C.M. and Dietz, H.C., Separable roles for rent1/hUpf1 in altered splicing and decay of nonsense transcripts. Science, 2002, 298, 419-422.
    • (2002) Science , vol.298 , pp. 419-422
    • Mendell, J.T.1    ap Rhys, C.M.2    Dietz, H.C.3
  • 16
    • 0036809882 scopus 로고    scopus 로고
    • Nonsense-associated altered splicing, a frame-dependent response distinct from nonsense-mediated decay
    • Wang, J., Chang, Y.F., Hamilton, J.I. and Wilkinson, M.F., Nonsense-associated altered splicing, a frame-dependent response distinct from nonsense-mediated decay. Mol. Cell., 2002, 10, 951-957.
    • (2002) Mol. Cell , vol.10 , pp. 951-957
    • Wang, J.1    Chang, Y.F.2    Hamilton, J.I.3    Wilkinson, M.F.4
  • 17
    • 0027242173 scopus 로고
    • Stabilization and ribosome association of unspliced pre-mRNAs in a yeast upf1 mutant
    • He, F., Peltz, S.W., Donahue, J.L., Rosbash, M. and Jacobson, A., Stabilization and ribosome association of unspliced pre-mRNAs in a yeast upf1 mutant. Proc. Natl. Acad. Sci. USA, 1993, 90, 7034-7038.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 7034-7038
    • He, F.1    Peltz, S.W.2    Donahue, J.L.3    Rosbash, M.4    Jacobson, A.5
  • 18
    • 0033856880 scopus 로고    scopus 로고
    • Unproductively spliced ribosomal protein mRNAs are natural targets of mRNA surveillance in C. elegans
    • Mitrovich, Q.M. and Anderson, P., Unproductively spliced ribosomal protein mRNAs are natural targets of mRNA surveillance in C. elegans. Genes Dev., 2000, 14, 2173-2184.
    • (2000) Genes Dev. , vol.14 , pp. 2173-2184
    • Mitrovich, Q.M.1    Anderson, P.2
  • 19
    • 0030931561 scopus 로고    scopus 로고
    • smg mutants affect the expression of alternatively spliced SR protein mRNAs in Caenorhabditis elegans
    • Morrison, M., Harris, K.S. and Roth, M.B., smg mutants affect the expression of alternatively spliced SR protein mRNAs in Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA, 1997, 94, 9782-9785.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 9782-9785
    • Morrison, M.1    Harris, K.S.2    Roth, M.B.3
  • 20
    • 0032825494 scopus 로고    scopus 로고
    • Yeast Upf proteins required for RNA surveillance affect global expression of the yeast transcriptome
    • Lelivelt, M.J. and Culbertson, M.R., Yeast Upf proteins required for RNA surveillance affect global expression of the yeast transcriptome. Mol. Cell. Biol. 1999, 19, 6710-6719.
    • (1999) Mol. Cell Biol. , vol.19 , pp. 6710-6719
    • Lelivelt, M.J.1    Culbertson, M.R.2
  • 21
    • 0037422575 scopus 로고    scopus 로고
    • Evidence for the widespread coupling of alternative splicing and non sense-mediated mRNA decay in humans
    • Lewis, B.P., Green, R.E. and Brenner, S.E., Evidence for the widespread coupling of alternative splicing and non sense-mediated mRNA decay in humans. Proc. Natl. Acad. Sci. USA, 2003, 100, 189-192.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 189-192
    • Lewis, B.P.1    Green, R.E.2    Brenner, S.E.3
  • 22
    • 0031896755 scopus 로고    scopus 로고
    • Selenium deficiency reduces the abundance of mRNA for Se-dependent glutathione peroxidase 1 by a UGA-dependent mechanism likely to be nonsense codon-mediated decay of cytoplasmic mRNA
    • Moriarty, P.M., Reddy, C.C. and Maquat, L.E., Selenium deficiency reduces the abundance of mRNA for Se-dependent glutathione peroxidase 1 by a UGA-dependent mechanism likely to be nonsense codon-mediated decay of cytoplasmic mRNA. Mol. Cell. Biol., 1998, 18, 2932-2939.
    • (1998) Mol. Cell Biol. , vol.18 , pp. 2932-2939
    • Moriarty, P.M.1    Reddy, C.C.2    Maquat, L.E.3
  • 23
    • 0034282528 scopus 로고    scopus 로고
    • Nonsense-mediated decay of glutathione peroxidase 1 mRNA in the cytoplasm depends on intron position
    • Sun, X., Moriarty, P.M. and Maquat, L.E., Nonsense-mediated decay of glutathione peroxidase 1 mRNA in the cytoplasm depends on intron position. EMBO J., 2000, 19, 4734-4744.
    • (2000) EMBO J. , vol.19 , pp. 4734-4744
    • Sun, X.1    Moriarty, P.M.2    Maquat, L.E.3
  • 24
    • 0035862813 scopus 로고    scopus 로고
    • Rent1, a trans-effector of nonsense-mediated mRNA decay, is essential for mammalian embryonic viability
    • Medghalchi, S.M., Frischmeyer, P.A., Mendell, J.T., Kelly, A.G., Lawler, A.M. and Dietz, H.C., Rent1, a trans-effector of nonsense-mediated mRNA decay, is essential for mammalian embryonic viability. Hum. Mol. Genet., 2001, 10, 99-105.
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 99-105
    • Medghalchi, S.M.1    Frischmeyer, P.A.2    Mendell, J.T.3    Kelly, A.G.4    Lawler, A.M.5    Dietz, H.C.6
  • 25
    • 0009461277 scopus 로고
    • Interference of nonsense mutations with eukaryotic messenger RNA stability
    • Losson, R. and Lacroute, F., Interference of nonsense mutations with eukaryotic messenger RNA stability. Proc. Natl. Acad. Sci. USA, 1979, 76, 5134-5137.
    • (1979) Proc. Natl. Acad. Sci. USA , vol.76 , pp. 5134-5137
    • Losson, R.1    Lacroute, F.2
  • 26
    • 0019733025 scopus 로고
    • Unstable β-globin mRNA in mRNA-deficient β° thalassemia
    • Maquat, L.E., Kinniburgh, A.J., Rachmilewitz, E.A. and Ross, J. Unstable β-globin mRNA in mRNA-deficient β° thalassemia. Cell, 1981, 27, 543-553.
    • (1981) Cell , vol.27 , pp. 543-553
    • Maquat, L.E.1    Kinniburgh, A.J.2    Rachmilewitz, E.A.3    Ross, J.4
  • 28
    • 0026773782 scopus 로고
    • Gene products that promote mRNA turnover in Saccharomyces cetevisiae
    • Leeds, P., Wood, J.M., Lee, B.S. and Culbertson, M.R., Gene products that promote mRNA turnover in Saccharomyces cetevisiae. Mol. Cell. Biol., 1992, 12, 2165-2177.
    • (1992) Mol. Cell Biol. , vol.12 , pp. 2165-2177
    • Leeds, P.1    Wood, J.M.2    Lee, B.S.3    Culbertson, M.R.4
  • 29
    • 0029348072 scopus 로고
    • Purification and characterization of the Upf1 protein, a factor involved in translation and mRNA degradation
    • Czaplinski, K., Weng, Y., Hagan, K.W. and Peltz, S.W., Purification and characterization of the Upf1 protein, a factor involved in translation and mRNA degradation. RNA, 1995, 1, 610-623.
    • (1995) RNA , vol.1 , pp. 610-623
    • Czaplinski, K.1    Weng, Y.2    Hagan, K.W.3    Peltz, S.W.4
  • 30
    • 0029791449 scopus 로고    scopus 로고
    • Genetic and biochemical characterization of mutations in the ATPase and helicase regions of the Upf1 protein
    • Weng. Y., Czaplinski, K. and Peltz, S.W., Genetic and biochemical characterization of mutations in the ATPase and helicase regions of the Upf1 protein. Mol. Cell. Biol., 1996, 16, 5477-5490.
    • (1996) Mol. Cell Biol. , vol.16 , pp. 5477-5490
    • Weng, Y.1    Czaplinski, K.2    Peltz, S.W.3
  • 31
    • 0029790557 scopus 로고    scopus 로고
    • Identification and characterization of mutations in the UPF1 gene that affect nonsense suppression and the formation of the Upf protein complex but not mRNA turnover
    • Weng, Y., Czaplinski, K. and Peitz, S.W., Identification and characterization of mutations in the UPF1 gene that affect nonsense suppression and the formation of the Upf protein complex but not mRNA turnover. Mol. Cell. Biol., 1996, 16, 5491-5506.
    • (1996) Mol. Cell Biol. , vol.16 , pp. 5491-5506
    • Weng, Y.1    Czaplinski, K.2    Peitz, S.W.3
  • 32
    • 0031940931 scopus 로고    scopus 로고
    • ATP is a cofactor of the Upf1 protein that modulates its translation termination and RNA binding activities
    • Weng, Y., Czaplinski K. and Peltz S.W., ATP is a cofactor of the Upf1 protein that modulates its translation termination and RNA binding activities. RNA, 1998, 4, 205-214.
    • (1998) RNA , vol.4 , pp. 205-214
    • Weng, Y.1    Czaplinski, K.2    Peltz, S.W.3
  • 33
    • 0028934876 scopus 로고
    • Identification and characterization of genes that are required for the accelerated degradation of mRNAs containing a premature translational termination codon
    • Cui, Y., Hagan, K.W., Zhang, S. and Peltz, S.W., Identification and characterization of genes that are required for the accelerated degradation of mRNAs containing a premature translational termination codon. Genes Dev., 1995, 9, 423-436.
    • (1995) Genes Dev. , vol.9 , pp. 423-436
    • Cui, Y.1    Hagan, K.W.2    Zhang, S.3    Peltz, S.W.4
  • 34
    • 0028948708 scopus 로고
    • Identification of a novel component of the nonsense-mediated mRNA decay pathway by use of an interacting protein screen
    • He, F. and Jacobson, A., Identification of a novel component of the nonsense-mediated mRNA decay pathway by use of an interacting protein screen. Genes Dev., 1995, 9, 437-454.
    • (1995) Genes Dev. , vol.9 , pp. 437-454
    • He, F.1    Jacobson, A.2
  • 35
    • 0028862895 scopus 로고
    • Identification of an additional gene required for eukaryotic nonsense mRNA turnover
    • Lee, B.S. and Culbertson, M.R., Identification of an additional gene required for eukaryotic nonsense mRNA turnover. Proc. Natl. Acad. Sci. USA, 1995, 92, 10354-tO358.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 10354-10358
    • Lee, B.S.1    Culbertson, M.R.2
  • 36
    • 0031720742 scopus 로고    scopus 로고
    • A factor required for nonsense-mediated mRNA decay in yeast is exported from the nucleus to the cytoplasm by a nuclear export signal sequence
    • Shirley, R.L., Lelivelt, M.J., Schenkman, L.R., Dahlseid, J.N. and Culbertson, M.R., A factor required for nonsense-mediated mRNA decay in yeast is exported from the nucleus to the cytoplasm by a nuclear export signal sequence. J. Cell. Sci., 1998, 111, 3129-3143.
    • (1998) J. Cell Sci. , vol.111 , pp. 3129-3143
    • Shirley, R.L.1    Lelivelt, M.J.2    Schenkman, L.R.3    Dahlseid, J.N.4    Culbertson, M.R.5
  • 37
    • 0029006870 scopus 로고
    • The majority of yeast UPF1 co-localizes with polyribosomes in the cytoplasm
    • Atkin, A.L., Altamura, N., Leeds, P. and Culbertson, M.R., The majority of yeast UPF1 co-localizes with polyribosomes in the cytoplasm. Mol. Biol. Cell. 1995, 6, 611-625.
    • (1995) Mol. Biol. Cell , vol.6 , pp. 611-625
    • Atkin, A.L.1    Altamura, N.2    Leeds, P.3    Culbertson, M.R.4
  • 39
    • 0029842901 scopus 로고    scopus 로고
    • Interaction between Nmd2p and Upf1p is required for activity but not for dominant-negative inhibition of the nonsense-mediated mRNA decay pathway in yeast
    • He, F., Brown, A.H. and Jacobson, A., Interaction between Nmd2p and Upf1p is required for activity but not for dominant-negative inhibition of the nonsense-mediated mRNA decay pathway in yeast. RNA, 1996, 2, 153-170.
    • (1996) RNA , vol.2 , pp. 153-170
    • He, F.1    Brown, A.H.2    Jacobson, A.3
  • 40
    • 0031025296 scopus 로고    scopus 로고
    • Upf1p, Nmd2p, and Upf3p are interacting components of the yeast nonsense-mediated mRNA decay pathway
    • He, F., Brown, A.H. and Jacobson, A., Upf1p, Nmd2p, and Upf3p are interacting components of the yeast nonsense-mediated mRNA decay pathway. Mol. Cell. Biol., 1997, 17, 1580-1594.
    • (1997) Mol. Cell Biol. , vol.17 , pp. 1580-1594
    • He, F.1    Brown, A.H.2    Jacobson, A.3
  • 42
    • 0035865408 scopus 로고    scopus 로고
    • The role of Upf proteins in modulating the translation read-through of nonsense-containing transcripts
    • Wang, W., Czaplinski, K., Rao, Y. and Peltz, S.W., The role of Upf proteins in modulating the translation read-through of nonsense-containing transcripts. EMBO J., 2001, 20, 880-890.
    • (2001) EMBO J. , vol.20 , pp. 880-890
    • Wang, W.1    Czaplinski, K.2    Rao, Y.3    Peltz, S.W.4
  • 43
    • 0033942924 scopus 로고    scopus 로고
    • Nonsense-mediated decay mutants do not affect programmed-1 frameshifting
    • Bidou, L., Stahl, G., Hatin, I., Namy, O., Rousset, J.P. and Farabaugh, P.J., Nonsense-mediated decay mutants do not affect programmed-1 frameshifting. RNA, 2000, 6, 952-961.
    • (2000) RNA , vol.6 , pp. 952-961
    • Bidou, L.1    Stahl, G.2    Hatin, I.3    Namy, O.4    Rousset, J.P.5    Farabaugh, P.J.6
  • 44
    • 0035137307 scopus 로고    scopus 로고
    • Upf1p, Nmd2p, and Upf3p regulate the decapping and exonucleolytic degradation of both nonsense-containing mRNAs and wild-type mRNAs
    • He, F. and Jacobson, A., Upf1p, Nmd2p, and Upf3p regulate the decapping and exonucleolytic degradation of both nonsense-containing mRNAs and wild-type mRNAs. Mol. Cell. Biol., 2001, 21, 1515-1530.
    • (2001) Mol. Cell Biol. , vol.21 , pp. 1515-1530
    • He, F.1    Jacobson, A.2
  • 45
    • 0032741067 scopus 로고    scopus 로고
    • Recognition of yeast mRNAs as "nonsense containing" leads to both inhibition of mRNA translation and mRNA degradation, implications for the control of mRNA decapping
    • Muhlrad, D. and Parker, R., Recognition of yeast mRNAs as "nonsense containing" leads to both inhibition of mRNA translation and mRNA degradation, implications for the control of mRNA decapping. Mol. Biol. Cell., 1999, 10, 3971-3978.
    • (1999) Mol. Biol. Cell , vol.10 , pp. 3971-3978
    • Muhlrad, D.1    Parker, R.2
  • 46
    • 0037762554 scopus 로고    scopus 로고
    • An NMD pathway in yeast involving accelerated deadenylation and exosome-mediated 3′-->5′ degradation
    • Mitchell, P. and Tollervey, D., An NMD pathway in yeast involving accelerated deadenylation and exosome-mediated 3′-->5′ degradation. Mol. Cell., 2003, 11, 1405-1413.
    • (2003) Mol. Cell , vol.11 , pp. 1405-1413
    • Mitchell, P.1    Tollervey, D.2
  • 47
    • 0038402506 scopus 로고    scopus 로고
    • Computational modeling and experimental analysis of nonsense-mediated decay in yeast
    • Cao, D. and Parker, R., Computational modeling and experimental analysis of nonsense-mediated decay in yeast. Cell, 2003, 113, 533-545.
    • (2003) Cell , vol.113 , pp. 533-545
    • Cao, D.1    Parker, R.2
  • 48
    • 0027932513 scopus 로고
    • Premature translational termination triggers mRNA decapping
    • Muhlrad, D. and Parker, R., Premature translational termination triggers mRNA decapping. Nature, 1994, 370, 578-581.
    • (1994) Nature , vol.370 , pp. 578-581
    • Muhlrad, D.1    Parker, R.2
  • 49
    • 0030951767 scopus 로고    scopus 로고
    • Polysome-associated mRNAs are substrates for the nonsense-mediated mRNA decay pathway in Saccharomyces cerevisiae
    • Zhang, S., Welch, E.M., Hogan, K., Brown, A.H., Peltz, S.W. and Jacobson, A., Polysome-associated mRNAs are substrates for the nonsense-mediated mRNA decay pathway in Saccharomyces cerevisiae. RNA, 1997, 3, 234-244.
    • (1997) RNA , vol.3 , pp. 234-244
    • Zhang, S.1    Welch, E.M.2    Hogan, K.3    Brown, A.H.4    Peltz, S.W.5    Jacobson, A.6
  • 50
    • 0037304372 scopus 로고    scopus 로고
    • Nonsense-containing mRNAs that accumulate in the absence of a functional nonsense-mediated mRNA decay pathway are destabilized rapidly upon its restitution
    • Maderazo, A.B., Belk, J.P., He, F. and Jacobson, A., Nonsense-containing mRNAs that accumulate in the absence of a functional nonsense-mediated mRNA decay pathway are destabilized rapidly upon its restitution. Mol. Cell. Biol., 2003, 23, 842-851.
    • (2003) Mol. Cell Biol. , vol.23 , pp. 842-851
    • Maderazo, A.B.1    Belk, J.P.2    He, F.3    Jacobson, A.4
  • 51
    • 0034839596 scopus 로고    scopus 로고
    • Computational modeling of eukaryotic mRNA turnover
    • Cao, D. and Parker, R., Computational modeling of eukaryotic mRNA turnover. RNA, 2001, 7, 1192-1211
    • (2001) RNA , vol.7 , pp. 1192-1211
    • Cao, D.1    Parker, R.2
  • 52
    • 0041524062 scopus 로고    scopus 로고
    • Interaction between Ski7p and Upf1p is required for nonsense-mediated 3′-to-5′ mRNA decay in yeast
    • Takahashi, S., Araki, Y., Sakuno, T. and Katada, T., Interaction between Ski7p and Upf1p is required for nonsense-mediated 3′-to-5′ mRNA decay in yeast. EMBO J., 2003, 22, 3951-3959.
    • (2003) EMBO J. , vol.22 , pp. 3951-3959
    • Takahashi, S.1    Araki, Y.2    Sakuno, T.3    Katada, T.4
  • 53
    • 0036792048 scopus 로고    scopus 로고
    • mRNA decay enzymes, decappers conserved between yeast and mammals
    • Decker, C.J. and Parker, R., mRNA decay enzymes, decappers conserved between yeast and mammals. Proc. Natl. Acad. Sci. USA, 2002, 99, 12512-12514.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 12512-12514
    • Decker, C.J.1    Parker, R.2
  • 54
    • 0028945345 scopus 로고
    • Identification and characterization of a sequence motif involved in nonscrise-mediated mRNA decay
    • Zhang, S., Ruiz-Echevarria, M.J., Quan. Y. and Peltz, S.W., Identification and characterization of a sequence motif involved in nonscrise-mediated mRNA decay. Mol. Cell. Biol., 1995, 15, 2231-2244.
    • (1995) Mol. Cell Biol. , vol.15 , pp. 2231-2244
    • Zhang, S.1    Ruiz-Echevarria, M.J.2    Quan, Y.3    Peltz, S.W.4
  • 55
    • 18844463753 scopus 로고    scopus 로고
    • Identifying the right stop, determining how the surveillance complex recognizes and degrades an aberrant mRNA
    • Ruiz-Echevarria, M.J., Gonzalez, C.I. and Peltz, S.W., Identifying the right stop, determining how the surveillance complex recognizes and degrades an aberrant mRNA. EMBO J., 1998, 17, 575-589.
    • (1998) EMBO J. , vol.17 , pp. 575-589
    • Ruiz-Echevarria, M.J.1    Gonzalez, C.I.2    Peltz, S.W.3
  • 56
    • 0033016753 scopus 로고    scopus 로고
    • mRNA surveillance in eukaryotes, kinetic proofreading of proper translation termination as assessed by mRNP domain organization?
    • Hilleren, P. and Parker, R., mRNA surveillance in eukaryotes, kinetic proofreading of proper translation termination as assessed by mRNP domain organization? RNA, 1999, 5, 711-719.
    • (1999) RNA , vol.5 , pp. 711-719
    • Hilleren, P.1    Parker, R.2
  • 57
    • 0027219029 scopus 로고
    • mRNA destabilization triggered by premature translational termination depends on at least three cis-acting sequence elements and one trans-acting factor
    • Peltz, S.W., Brown, A.H. and Jacobson, A., mRNA destabilization triggered by premature translational termination depends on at least three cis-acting sequence elements and one trans-acting factor. Genes Dev., 1993, 7, 1737-1754.
    • (1993) Genes Dev. , vol.7 , pp. 1737-1754
    • Peltz, S.W.1    Brown, A.H.2    Jacobson, A.3
  • 58
    • 0033679905 scopus 로고    scopus 로고
    • The yeast hnRNP-like protein Hrp1/Nab4 marks a transcript for nonsense-mediated mRNA decay
    • Gonzalez, C.I., Ruiz-Echevarria, M.J., Vasudevan. S., Henry, M.F. and Peltz, S.W., The yeast hnRNP-like protein Hrp1/Nab4 marks a transcript for nonsense-mediated mRNA decay. Mol. Cell., 2000, 5, 489-499.
    • (2000) Mol. Cell , vol.5 , pp. 489-499
    • Gonzalez, C.I.1    Ruiz-Echevarria, M.J.2    Vasudevan, S.3    Henry, M.F.4    Peltz, S.W.5
  • 59
    • 0032880399 scopus 로고    scopus 로고
    • Aberrant mRNAs with extended 3′ UTRs are substrates for rapid degradation by mRNA surveillance
    • Muhlrad, D. and Parker, R., Aberrant mRNAs with extended 3′ UTRs are substrates for rapid degradation by mRNA surveillance. RNA, 1999, 5, 1299-1307.
    • (1999) RNA , vol.5 , pp. 1299-1307
    • Muhlrad, D.1    Parker, R.2
  • 60
    • 0037968357 scopus 로고    scopus 로고
    • Decapping and decay of messenger RNA occur in cytoplasmic processing bodies
    • Sheth, U. and Parker, R., Decapping and decay of messenger RNA occur in cytoplasmic processing bodies. Science. 2003, 300, 805-808.
    • (2003) Science , vol.300 , pp. 805-808
    • Sheth, U.1    Parker, R.2
  • 61
    • 0034705289 scopus 로고    scopus 로고
    • The RNA binding protein Pub1 modulates the stability of transcripts containing upstream open reading frames
    • Ruiz-Echevarria, M.J. and Peltz, S.W., The RNA binding protein Pub1 modulates the stability of transcripts containing upstream open reading frames. Cell, 2000, 101, 741-751.
    • (2000) Cell , vol.101 , pp. 741-751
    • Ruiz-Echevarria, M.J.1    Peltz, S.W.2
  • 62
    • 0034460323 scopus 로고    scopus 로고
    • Novel Upf2p orthologues suggest a functional link between translation initiation and nonsense surveillance complexes
    • Mendell, J.T., Medghalchi, S.M., Lake, R.G., Noensie, E.N. and Dietz, H.C., Novel Upf2p orthologues suggest a functional link between translation initiation and nonsense surveillance complexes. Mol. Cell. Biol., 2000, 20, 8944-8957.
    • (2000) Mol. Cell Biol. , vol.20 , pp. 8944-8957
    • Mendell, J.T.1    Medghalchi, S.M.2    Lake, R.G.3    Noensie, E.N.4    Dietz, H.C.5
  • 63
    • 0024444026 scopus 로고
    • A new kind of informational suppression in the nematode Caenorhabditis elegans
    • Hodgkin, J., Papp, A., Pulak, R., Ambros, V. and Anderson, P., A new kind of informational suppression in the nematode Caenorhabditis elegans. Genetics, 1989, 123, 301-313.
    • (1989) Genetics , vol.123 , pp. 301-313
    • Hodgkin, J.1    Papp, A.2    Pulak, R.3    Ambros, V.4    Anderson, P.5
  • 64
    • 0032940802 scopus 로고    scopus 로고
    • smg-7 is required for mRNA surveillance in Caenorhabditis elegans
    • Cali, B.M., Kuchma, S.L., Latham, J. and Anderson, P., smg-7 is required for mRNA surveillance in Caenorhabditis elegans. Genetics, 1999, 151, 605-616.
    • (1999) Genetics , vol.151 , pp. 605-616
    • Cali, B.M.1    Kuchma, S.L.2    Latham, J.3    Anderson, P.4
  • 65
    • 0032771414 scopus 로고    scopus 로고
    • SMG-2 is a phosphorylated protein required for mRNA surveillance in Caenorhabditis elegans and related to Upf1p of yeast
    • Page, M.F., Carr, B., Anders, K.R., Grimson, A. and Anderson, P., SMG-2 is a phosphorylated protein required for mRNA surveillance in Caenorhabditis elegans and related to Upf1p of yeast. Mol. Cell. Biol., 1999, 19, 5943-5951.
    • (1999) Mol. Cell Biol. , vol.19 , pp. 5943-5951
    • Page, M.F.1    Carr, B.2    Anders, K.R.3    Grimson, A.4    Anderson, P.5
  • 66
    • 0037415691 scopus 로고    scopus 로고
    • SMG-5, required for C.elegans nonsense-mediated mRNA decay, associates with SMG-2 and protein phosphatase 2A
    • Anders, K.R., Grimson, A. and Anderson, P., SMG-5, required for C.elegans nonsense-mediated mRNA decay, associates with SMG-2 and protein phosphatase 2A. EMBO J., 2003, 22, 641-650.
    • (2003) EMBO J. , vol.22 , pp. 641-650
    • Anders, K.R.1    Grimson, A.2    Anderson, P.3
  • 67
    • 0034649546 scopus 로고    scopus 로고
    • PIN domains in nonsense-mediated mRNA decay and RNAi
    • Clissold, P.M. and Ponting, C.P., PIN domains in nonsense-mediated mRNA decay and RNAi. Curr. Biol., 2000, 10, R888-890.
    • (2000) Curr. Biol. , vol.10
    • Clissold, P.M.1    Ponting, C.P.2
  • 68
    • 0032956684 scopus 로고    scopus 로고
    • Nonsense mutations in the alcohol dehydrogenase gene of Drosophila melanogaster correlate with an abnormal 3′ end processing of the corresponding pre-mRNA
    • Brogna, S., Nonsense mutations in the alcohol dehydrogenase gene of Drosophila melanogaster correlate with an abnormal 3′ end processing of the corresponding pre-mRNA. RNA, 1999, 5, 562-573.
    • (1999) RNA , vol.5 , pp. 562-573
    • Brogna, S.1
  • 70
    • 0024639665 scopus 로고
    • A frameshift mutation prevents Kunitz trypsin inhibitor mRNA accumulation in soybean embryos
    • Jofuku, K.D., Schipper, R.D. and Goldberg, R.B., A frameshift mutation prevents Kunitz trypsin inhibitor mRNA accumulation in soybean embryos. Plant Cell., 1989, 1, 427-435.
    • (1989) Plant. Cell , vol.1 , pp. 427-435
    • Jofuku, K.D.1    Schipper, R.D.2    Goldberg, R.B.3
  • 71
    • 0028485367 scopus 로고
    • Light modulation of ferredoxin mRNA abundance requires an open reading frame
    • Dickey, L.F., Nguyen, T.T., Allen, G.C. and Thompson, W.F., Light modulation of ferredoxin mRNA abundance requires an open reading frame. Plant Cell., 1994, 6, 1171-1176.
    • (1994) Plant. Cell , vol.6 , pp. 1171-1176
    • Dickey, L.F.1    Nguyen, T.T.2    Allen, G.C.3    Thompson, W.F.4
  • 72
    • 0000080943 scopus 로고
    • Molecular analysis of two phytohemagglutinin genes and their expression in Phaseolus vulgaris cv. Pinto, a lectin-deficient cultivar of the bean
    • Voelker, T.A., Staswick, P. and Chrispeels, M.J., Molecular analysis of two phytohemagglutinin genes and their expression in Phaseolus vulgaris cv. Pinto, a lectin-deficient cultivar of the bean. EMBO J., 1986, 5, 3075-3082.
    • (1986) EMBO J. , vol.5 , pp. 3075-3082
    • Voelker, T.A.1    Staswick, P.2    Chrispeels, M.J.3
  • 73
    • 0030238338 scopus 로고    scopus 로고
    • Premature nonsense codons decrease the stability of phytohemagglutinin in mRNA in a position-dependent manner
    • van Hoof, A. and Green, P.J., Premature nonsense codons decrease the stability of phytohemagglutinin in mRNA in a position-dependent manner. Plant J., 1996, 10, 415-424.
    • (1996) Plant. J. , vol.10 , pp. 415-424
    • van Hoof, A.1    Green, P.J.2
  • 75
    • 0033996462 scopus 로고    scopus 로고
    • Premature termination codons destabilize ferredoxin-1 mRNA when ferredoxin-1 is translated
    • Petracek, M.E., Nuygen, T., Thompson, W.F. and Dickey, L.F., Premature termination codons destabilize ferredoxin-1 mRNA when ferredoxin-1 is translated. Plant. J., 2000, 21, 563-569.
    • (2000) Plant. J. , vol.21 , pp. 563-569
    • Petracek, M.E.1    Nuygen, T.2    Thompson, W.F.3    Dickey, L.F.4
  • 76
    • 0035099557 scopus 로고    scopus 로고
    • Nonsense-mediated decay of mutant waxy mRNA in rice
    • Isshiki, M., Yamamoto, Y., Satoh, H. and Shimamoto, K., Nonsense-mediated decay of mutant waxy mRNA in rice. Plant Physiol., 2001, 125, 1388-1395.
    • (2001) Plant Physiol. , vol.125 , pp. 1388-1395
    • Isshiki, M.1    Yamamoto, Y.2    Satoh, H.3    Shimamoto, K.4
  • 77
    • 0027536976 scopus 로고
    • Nonsense codons can reduce the abundance of nuclear mRNA without affecting the abundance of pre-mRNA or the half-life of cytoplasmic mRNA
    • Cheng, J. and Maquat, L.E., Nonsense codons can reduce the abundance of nuclear mRNA without affecting the abundance of pre-mRNA or the half-life of cytoplasmic mRNA. Mol. Cell. Biol., 1993, 13, 1892-1902.
    • (1993) Mol. Cell Biol. , vol.13 , pp. 1892-1902
    • Cheng, J.1    Maquat, L.E.2
  • 78
    • 0028125262 scopus 로고
    • Mammalian nonsense codons can be cis effectors of nuclear mRNA half-life
    • Belgrader, P., Cheng, J., Zhou, X., Stephenson, L.S. and Maquat, L.E., Mammalian nonsense codons can be cis effectors of nuclear mRNA half-life. Mol. Cell. Biol., 1994, 14, 8219-9228.
    • (1994) Mol. Cell Biol. , vol.14 , pp. 8219-9228
    • Belgrader, P.1    Cheng, J.2    Zhou, X.3    Stephenson, L.S.4    Maquat, L.E.5
  • 79
    • 0141819096 scopus 로고    scopus 로고
    • Nonsense-mediated mRNA decay in mammalian cells involves decapping, deadenylating, and exonucleolytic activities
    • Lejeune, F., Li, X. and Maquat, L.E., Nonsense-mediated mRNA decay in mammalian cells involves decapping, deadenylating, and exonucleolytic activities. Mol. Cell., 2003, 12, 675-687.
    • (2003) Mol. Cell , vol.12 , pp. 675-687
    • Lejeune, F.1    Li, X.2    Maquat, L.E.3
  • 80
    • 0027410487 scopus 로고
    • T cell receptor-β mRNA splicing, regulation of unusual splicing intermediates
    • Qian, L., Theodor, L., Carter, M., Vu, M.N., Sasaki, A.W. and Wilkinson, M.F., T cell receptor-β mRNA splicing, regulation of unusual splicing intermediates. Mol. Cell. Biol., 1993, 13, 1686-1696.
    • (1993) Mol. Cell Biol. , vol.13 , pp. 1686-1696
    • Qian, L.1    Theodor, L.2    Carter, M.3    Vu, M.N.4    Sasaki, A.W.5    Wilkinson, M.F.6
  • 81
    • 0028540401 scopus 로고
    • Evidence for degradation of mRNA encoding alpha-L-iduronidase in Hurler fibroblasts with premature termination alleles
    • Menon, K.P. and Neufeld, E.F., Evidence for degradation of mRNA encoding alpha-L-iduronidase in Hurler fibroblasts with premature termination alleles. Cell. Mol. Biol., 1994, 40, 999-1005.
    • (1994) Cell Mol. Biol. , vol.40 , pp. 999-1005
    • Menon, K.P.1    Neufeld, E.F.2
  • 82
    • 0028884942 scopus 로고
    • A regulatory mechanism that detects premature nonsense codons in T-cell receptor transcripts in vivo is reversed by protein synthesis inhibitors in vitro
    • Carter, M.S., Doskow, J., Morris, P., Li, S., Nhim, R.P., Sandstedt, S. and Wilkinson, M.F., A regulatory mechanism that detects premature nonsense codons in T-cell receptor transcripts in vivo is reversed by protein synthesis inhibitors in vitro. J. Biol. Chem., 1995, 270, 28995-29003.
    • (1995) J. Biol. Chem. , vol.270 , pp. 28995-29003
    • Carter, M.S.1    Doskow, J.2    Morris, P.3    Li, S.4    Nhim, R.P.5    Sandstedt, S.6    Wilkinson, M.F.7
  • 83
    • 0032530480 scopus 로고    scopus 로고
    • Proteolysis of human eukaryotic translation initiation factor eIF4GII, but not eIF4GI, coincides with the shutoff of host protein synthesis after poliovirus infection
    • Gradi, A., Svitkin, Y.V., Imataka, H. and Sonenberg, N., Proteolysis of human eukaryotic translation initiation factor eIF4GII, but not eIF4GI, coincides with the shutoff of host protein synthesis after poliovirus infection. Proc. Natl. Acad. Sci. USA, 1998, 95, 11089-11094.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 11089-11094
    • Gradi, A.1    Svitkin, Y.V.2    Imataka, H.3    Sonenberg, N.4
  • 84
    • 0036171240 scopus 로고    scopus 로고
    • Efficient cleavage of ribosome-associated poly(A)-binding protein by enterovirus 3C protease
    • Kuyumcu-Martinez, N.M., Joachims, M. and Lloyd, R.E., Efficient cleavage of ribosome-associated poly(A)-binding protein by enterovirus 3C protease. J. Virol., 2002, 76, 2062-2074.
    • (2002) J. Virol. , vol.76 , pp. 2062-2074
    • Kuyumcu-Martinez, N.M.1    Joachims, M.2    Lloyd, R.E.3
  • 85
    • 0027388887 scopus 로고
    • Evidence to implicate translation by ribosomes in the mechanism by which nonsense codons reduce the nuclear level of human triosephosphate isomerase mRNA
    • Belgrader, P., Cheng, J. and Maquat, L.E., Evidence to implicate translation by ribosomes in the mechanism by which nonsense codons reduce the nuclear level of human triosephosphate isomerase mRNA. Proc. Natl. Acad. Sci. USA, 1993, 90, 482-486.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 482-486
    • Belgrader, P.1    Cheng, J.2    Maquat, L.E.3
  • 87
    • 0031004756 scopus 로고    scopus 로고
    • T cell receptor (TCR) mini-gene mRNA expression regulated by nonsense codons, a nuclear-associated translation-like mechanism
    • Li, S., Leonard, D. and Wilkinson M.F., T cell receptor (TCR) mini-gene mRNA expression regulated by nonsense codons, a nuclear-associated translation-like mechanism. J. Exp. Med., 1997, 185, 985-992.
    • (1997) J. Exp. Med. , vol.185 , pp. 985-992
    • Li, S.1    Leonard, D.2    Wilkinson, M.F.3
  • 88
    • 0035823036 scopus 로고    scopus 로고
    • Evidence for a pioneer round of mRNA translation, mRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20
    • Ishigaki, Y., Li, X., Serin, G. and Maquat, L.E., Evidence for a pioneer round of mRNA translation, mRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20. Cell, 2001, 106, 607-617.
    • (2001) Cell , vol.106 , pp. 607-617
    • Ishigaki, Y.1    Li, X.2    Serin, G.3    Maquat, L.E.4
  • 89
    • 0036645697 scopus 로고    scopus 로고
    • The exon junction complex is detected on CBP80-bound but not eIF4E-bound mRNA in mammalian cells, dynamics of mRNP remodeling
    • Lejeune, F., Ishigaki, Y., Li, X. and Maquat, L.E., The exon junction complex is detected on CBP80-bound but not eIF4E-bound mRNA in mammalian cells, dynamics of mRNP remodeling. EMB0 J., 2002, 21, 3536-3545.
    • (2002) EMB0 J. , vol.21 , pp. 3536-3545
    • Lejeune, F.1    Ishigaki, Y.2    Li, X.3    Maquat, L.E.4
  • 91
    • 0030753073 scopus 로고    scopus 로고
    • The role of the cap structure in RNA processing and nuclear export
    • Lewis, J.D. and Izaurralde, E., The role of the cap structure in RNA processing and nuclear export. Eur. J. Biochem., 1997, 247, 461-469.
    • (1997) Eur. J. Biochem. , vol.247 , pp. 461-469
    • Lewis, J.D.1    Izaurralde, E.2
  • 92
    • 0026705268 scopus 로고
    • A fraction of the mRNA 5′ cap-binding protein, eukaryotic initiation factor 4E, localizes to the nucleus
    • Lejbkowicz, F., Guyer, C., Darveau, A., Neron, S., Lemieux, R. and Sonenberg, N., A fraction of the mRNA 5′ cap-binding protein, eukaryotic initiation factor 4E, localizes to the nucleus. Proc. Natl. Acad. Sci. USA, 1992, 89, 9612-9616.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 9612-9616
    • Lejbkowicz, F.1    Guyer, C.2    Darveau, A.3    Neron, S.4    Lemieux, R.5    Sonenberg, N.6
  • 93
    • 0032834055 scopus 로고    scopus 로고
    • eIF4 initiation factors, effectors of mRNA recruitment to ribosomes and regulators of translation
    • Gingras, A.C., Raught, B. and Sonenberg, N., eIF4 initiation factors, effectors of mRNA recruitment to ribosomes and regulators of translation. Annu. Rev. Biochem., 1999, 68, 913-963.
    • (1999) Annu. Rev. Biochem. , vol.68 , pp. 913-963
    • Gingras, A.C.1    Raught, B.2    Sonenberg, N.3
  • 94
    • 0033636895 scopus 로고    scopus 로고
    • The yeast nuclear cap binding complex can interact with translation factor eIF4G and mediate translation initiation
    • Fortes, P., Inada, T., Preiss, T., Hentze, M.W., Mattaj, I.W. and Sachs, A.B., The yeast nuclear cap binding complex can interact with translation factor eIF4G and mediate translation initiation. Mol. Cell., 2000, 6, 191-196.
    • (2000) Mol. Cell , vol.6 , pp. 191-196
    • Fortes, P.1    Inada, T.2    Preiss, T.3    Hentze, M.W.4    Mattaj, I.W.5    Sachs, A.B.6
  • 95
    • 0033956022 scopus 로고    scopus 로고
    • mRNA surveillance in mammalian cells, the relationship between introns and translation termination
    • Sun, X. and Maquat, L.E., mRNA surveillance in mammalian cells, the relationship between introns and translation termination. RNA. 2000, 6, 1-8.
    • (2000) RNA , vol.6 , pp. 1-8
    • Sun, X.1    Maquat, L.E.2
  • 96
    • 0027993583 scopus 로고
    • Introns are cis effectors of the nonsense-codon-mediated reduction in nuclear mRNA abundance
    • Cheng, J., Belgrader, P., Zhou, X. and Maquat, L.E., Introns are cis effectors of the nonsense-codon-mediated reduction in nuclear mRNA abundance. Mol. Cell. Biol., 1994, 14, 6317-6325.
    • (1994) Mol. Cell Biol. , vol.14 , pp. 6317-6325
    • Cheng, J.1    Belgrader, P.2    Zhou, X.3    Maquat, L.E.4
  • 97
    • 0029908912 scopus 로고    scopus 로고
    • A splicing-dependent regulatory mechanism that detects translation signals
    • Carter, M.S., Li, S. and Wilkinson M.F., A splicing-dependent regulatory mechanism that detects translation signals. EMBO J., 1996, 15, 5965-5975.
    • (1996) EMBO J. , vol.15 , pp. 5965-5975
    • Carter, M.S.1    Li, S.2    Wilkinson, M.F.3
  • 98
    • 0031840487 scopus 로고    scopus 로고
    • At least one intron is required for the nonsense-mediated decay of triosephosphate isomerase mRNA, a possible link between nuclear splicing and cytoplasmic translation
    • Zhang, J., Sun, X., Qian, Y., LaDuca, J.P. and Maquat, L.E., At least one intron is required for the nonsense-mediated decay of triosephosphate isomerase mRNA, a possible link between nuclear splicing and cytoplasmic translation. Mol. Cell. Biol., 1998, 18, 5272-5283.
    • (1998) Mol. Cell Biol. , vol.18 , pp. 5272-5283
    • Zhang, J.1    Sun, X.2    Qian, Y.3    LaDuca, J.P.4    Maquat, L.E.5
  • 99
    • 0031870169 scopus 로고    scopus 로고
    • Intron function in the nonsense-mediated decay of β-globin mRNA, indications that pre-mRNA splicing in the nucleus can influence mRNA translation in the cytoplasm
    • Zhang, J., Sun, X., Qian, Y. and Maquat, L.E., Intron function in the nonsense-mediated decay of β-globin mRNA, indications that pre-mRNA splicing in the nucleus can influence mRNA translation in the cytoplasm. RNA, 1998, 4, 801-815.
    • (1998) RNA , vol.4 , pp. 801-815
    • Zhang, J.1    Sun, X.2    Qian, Y.3    Maquat, L.E.4
  • 100
    • 0032104190 scopus 로고    scopus 로고
    • A rule for termination-codon position within intron-containing genes, when nonsense affects RNA abundance
    • Nagy, E. and Maquat, L.E., A rule for termination-codon position within intron-containing genes, when nonsense affects RNA abundance. Trends Biochem. Sci., 1998, 23, 198-199.
    • (1998) Trends Biochem. Sci. , vol.23 , pp. 198-199
    • Nagy, E.1    Maquat, L.E.2
  • 101
    • 0035028094 scopus 로고    scopus 로고
    • Mammalian heat shock p70 and historic H4 transcripts, which derive from naturally intronless genes, are immune to nonsense-mediated decay
    • Maquat, L.E. and Li, X., Mammalian heat shock p70 and historic H4 transcripts, which derive from naturally intronless genes, are immune to nonsense-mediated decay. RNA, 2001, 7, 445-456.
    • (2001) RNA , vol.7 , pp. 445-456
    • Maquat, L.E.1    Li, X.2
  • 103
    • 0031046735 scopus 로고    scopus 로고
    • Evidence that translation reinitiation abrogates nonsense-mediated mRNA decay in mammalian cells
    • Zhang, J. and Maquat, L.E., Evidence that translation reinitiation abrogates nonsense-mediated mRNA decay in mammalian cells. EMBO J., 1997, 16, 826-833.
    • (1997) EMBO J. , vol.16 , pp. 826-833
    • Zhang, J.1    Maquat, L.E.2
  • 104
    • 0035254681 scopus 로고    scopus 로고
    • Splicing and 3′ end formation in the definition of nonsense-mediated decay-competent human β-globin mRNPs
    • Neu-Yilik, G., Gehring, N.H., Thermann, R., Frede, U., Hentze, M.W. and Kulozik, A.E., Splicing and 3′ end formation in the definition of nonsense-mediated decay-competent human β-globin mRNPs. EMBO J., 2001, 20, 532-540.
    • (2001) EMBO J. , vol.20 , pp. 532-540
    • Neu-Yilik, G.1    Gehring, N.H.2    Thermann, R.3    Frede, U.4    Hentze, M.W.5    Kulozik, A.E.6
  • 105
    • 0041524056 scopus 로고    scopus 로고
    • The apolipoprotein B mRNA editing complex performs a multifunctional cycle and suppresses nonsense-mediated decay
    • Chester, A., Somasekaram, A., Tzimina, M., Jarmuz, A., Gisbourne, J., O'Keefe, R., Scott, J. and Navaratnam, N., The apolipoprotein B mRNA editing complex performs a multifunctional cycle and suppresses nonsense-mediated decay. EMBO J., 2003, 22, 3971-3982.
    • (2003) EMBO J. , vol.22 , pp. 3971-3982
    • Chester, A.1    Somasekaram, A.2    Tzimina, M.3    Jarmuz, A.4    Gisbourne, J.5    O'Keefe, R.6    Scott, J.7    Navaratnam, N.8
  • 106
    • 0034672093 scopus 로고    scopus 로고
    • The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions
    • Le Hir, H., Izaurralde, E., Maqual, L.E., and Moore, M.J., The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions. EMBO J., 2000, 19, 6860-6869.
    • (2000) EMBO J. , vol.19 , pp. 6860-6869
    • Le Hir, H.1    Izaurralde, E.2    Maqual, L.E.3    Moore, M.J.4
  • 107
    • 0034193569 scopus 로고    scopus 로고
    • Pre-mRNA splicing alters mRNP composition, evidence for stable association of proteins at exon-exon junctions
    • Le Hir, H., Moore, M.J. and Maquat, L.E., Pre-mRNA splicing alters mRNP composition, evidence for stable association of proteins at exon-exon junctions. Genes Dev., 2000, 14, 1098-1108.
    • (2000) Genes Dev. , vol.14 , pp. 1098-1108
    • Le Hir, H.1    Moore, M.J.2    Maquat, L.E.3
  • 108
    • 0036826885 scopus 로고    scopus 로고
    • 5′ exon interactions within file human spliceosome establish a framework for exon junction complex structure and assembly
    • Reichert, V.L., Le Hir, H., Jurica, M.S. and Moore, M.J., 5′ exon interactions within file human spliceosome establish a framework for exon junction complex structure and assembly. Genes Dev., 2002, 16, 2778-2791.
    • (2002) Genes Dev. , vol.16 , pp. 2778-2791
    • Reichert, V.L.1    Le Hir, H.2    Jurica, M.S.3    Moore, M.J.4
  • 109
    • 0035901565 scopus 로고    scopus 로고
    • The Y14 protein communicates to the cytoplasm the position of exon-exon junctions
    • Kim, V.N., Yong, J., Kataoka, N., Abel, L., Diem, M.D. and Dreyfuss, G., The Y14 protein communicates to the cytoplasm the position of exon-exon junctions. EMBO J., 2001, 20, 2062-2068.
    • (2001) EMBO J. , vol.20 , pp. 2062-2068
    • Kim, V.N.1    Yong, J.2    Kataoka, N.3    Abel, L.4    Diem, M.D.5    Dreyfuss, G.6
  • 110
    • 0036512117 scopus 로고    scopus 로고
    • Messenger-RNA-binding proteins and the messages they carry
    • Dreyfuss, G., Kim, V.N. and Kataoka, N., Messenger-RNA-binding proteins and the messages they carry. Nat. Rev. Mol. Cell. Biol., 2002, 3, 195-205.
    • (2002) Nat. Rev. Mol. Cell Biol. , vol.3 , pp. 195-205
    • Dreyfuss, G.1    Kim, V.N.2    Kataoka, N.3
  • 111
    • 0038699144 scopus 로고    scopus 로고
    • Coupling transcription, splicing and mRNA export
    • Reed, R., Coupling transcription, splicing and mRNA export. Curr. Opin. Cell. Biol., 2003, 15, 326-331.
    • (2003) Curr. Opin. Cell Biol. , vol.15 , pp. 326-331
    • Reed, R.1
  • 112
    • 0042671357 scopus 로고    scopus 로고
    • Pre-mRNA splicing, awash in a sea of proteins
    • Jurica, M.S. and Moore, M.J., Pre-mRNA splicing, awash in a sea of proteins. Mol. Cell., 2003, 12, 5-14.
    • (2003) Mol. Cell , vol.12 , pp. 5-14
    • Jurica, M.S.1    Moore, M.J.2
  • 113
    • 0038697629 scopus 로고    scopus 로고
    • The interplay of nuclear mRNP assembly, mRNA surveillance and export
    • Stutz, F. and Izaurralde, E., The interplay of nuclear mRNP assembly, mRNA surveillance and export. Trends Cell. Biol., 2003, 13, 319-327.
    • (2003) Trends Cell Biol. , vol.13 , pp. 319-327
    • Stutz, F.1    Izaurralde, E.2
  • 114
    • 0742323558 scopus 로고    scopus 로고
    • Nonsense-mediated mRNA decay, splicing, translation and mRNP dynamics
    • in press
    • Maquat, L.E., Nonsense-mediated mRNA decay, splicing, translation and mRNP dynamics. Nat. Reviews Cell. Biol., 2004, in press.
    • (2004) Nat. Reviews Cell Biol.
    • Maquat, L.E.1
  • 115
    • 0034704201 scopus 로고    scopus 로고
    • Human, Upf proteins target an mRNA for nonsense-mediated decay when bound downstream of a termination codon
    • Lykke-Andersen, J., Shu, M.D. and Steitz, J.A., Human, Upf proteins target an mRNA for nonsense-mediated decay when bound downstream of a termination codon. Cell, 2000, 103, 1121-1131.
    • (2000) Cell , vol.103 , pp. 1121-1131
    • Lykke-Andersen, J.1    Shu, M.D.2    Steitz, J.A.3
  • 116
    • 0034751160 scopus 로고    scopus 로고
    • Identification and characterization of human orthologues to Saccharomyces cerevisiae Upf2 protein and Upf3 protein (Caenorhabditis elegans SMG-4)
    • Serin, G., Gersappe, A., Black, J.D., Aronoff, R. and Maquat, L.E., Identification and characterization of human orthologues to Saccharomyces cerevisiae Upf2 protein and Upf3 protein (Caenorhabditis elegans SMG-4). Mol. Cell. Biol., 2001, 21, 209-223.
    • (2001) Mol. Cell Biol. , vol.21 , pp. 209-223
    • Serin, G.1    Gersappe, A.2    Black, J.D.3    Aronoff, R.4    Maquat, L.E.5
  • 118
    • 0037046798 scopus 로고    scopus 로고
    • Translation is required to remove Y14 from mRNAs in the cytoplasm
    • Dostie, J. and Dreyfuss, G., Translation is required to remove Y14 from mRNAs in the cytoplasm. Curr. Biol., 2002, 12, 1060-1067.
    • (2002) Curr. Biol. , vol.12 , pp. 1060-1067
    • Dostie, J.1    Dreyfuss, G.2
  • 119
    • 0035823247 scopus 로고    scopus 로고
    • Communication of the position of exon-exon junctions to the mRNA surveillance machinery by the protein RNPSI
    • Lykke-Andersen, J., Shu, M.D. and Steitz, J.A., Communication of the position of exon-exon junctions to the mRNA surveillance machinery by the protein RNPSI. Science, 2001, 293, 1836-1839.
    • (2001) Science , vol.293 , pp. 1836-1839
    • Lykke-Andersen, J.1    Shu, M.D.2    Steitz, J.A.3
  • 120
    • 0033634824 scopus 로고    scopus 로고
    • Pre-mRNA splicing imprints mRNA in the nucleus with a novel RNA-binding protein that persists in the cytoplasm
    • Kataoka, N., Yong, J., Kim, V.N., Velazquez, F., Perkinson, R.A., Wang, F. and Dreyfuss, G., Pre-mRNA splicing imprints mRNA in the nucleus with a novel RNA-binding protein that persists in the cytoplasm. Mol. Cell., 2000, 6, 673-682.
    • (2000) Mol. Cell , vol.6 , pp. 673-682
    • Kataoka, N.1    Yong, J.2    Kim, V.N.3    Velazquez, F.4    Perkinson, R.A.5    Wang, F.6    Dreyfuss, G.7
  • 121
    • 0037197986 scopus 로고    scopus 로고
    • Intron evolution as a population-genetic process
    • Lynch, M., Intron evolution as a population-genetic process. Proc. Natl. Acad. Sci. USA, 2002, 99, 6118-6123.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 6118-6123
    • Lynch, M.1
  • 122
    • 0025098474 scopus 로고
    • Exon definition may facilitate splice site selection in RNAs with multiple exons
    • Robberson, B.L., Cote, G.J. and Berget. S.M., Exon definition may facilitate splice site selection in RNAs with multiple exons. Mol. Cell. Biol., 1990, 10, 84-94.
    • (1990) Mol. Cell Biol. , vol.10 , pp. 84-94
    • Robberson, B.L.1    Cote, G.J.2    Berget, S.M.3
  • 123
    • 0027175493 scopus 로고
    • Sequences within the last intron function in RNA 3′-end formation in cultured cells
    • Nesic, D., Cheng, J. and Maquat, L.E., Sequences within the last intron function in RNA 3′-end formation in cultured cells. Mol. Cell. Biol., 1993, 13, 3359-3369.
    • (1993) Mol. Cell Biol. , vol.13 , pp. 3359-3369
    • Nesic, D.1    Cheng, J.2    Maquat, L.E.3
  • 124
    • 0026495280 scopus 로고
    • Are vertebrate exons scanned during splice-site selection?
    • Niwa, M., MacDonald, C.C. and Berget, S.M., Are vertebrate exons scanned during splice-site selection? Nature, 1992, 360, 277-280.
    • (1992) Nature , vol.360 , pp. 277-280
    • Niwa, M.1    MacDonald, C.C.2    Berget, S.M.3
  • 125
    • 0024988383 scopus 로고
    • In vitro polyadenylation is stimulated by the presence of an upstream intron
    • Niwa, M., Rose, S.D. and Berget, S.M., In vitro polyadenylation is stimulated by the presence of an upstream intron. Genes Dev., 1990, 4, 1552-1559.
    • (1990) Genes Dev. , vol.4 , pp. 1552-1559
    • Niwa, M.1    Rose, S.D.2    Berget, S.M.3
  • 126
    • 0028010715 scopus 로고
    • Upstream introns influence the efficiency of final intron removal and RNA 3′-end formation
    • Nesic, D. and Maquat, L.E., Upstream introns influence the efficiency of final intron removal and RNA 3′-end formation. Genes Dev., 1994, 8, 363-375.
    • (1994) Genes Dev. , vol.8 , pp. 363-375
    • Nesic, D.1    Maquat, L.E.2
  • 127
    • 0033000782 scopus 로고    scopus 로고
    • Utilization of splicing elements and polyadenylation signal elements in the coupling of polyadenylation and last-intron removal
    • Cooke, C., Hans, H. and Alwine, J.C., Utilization of splicing elements and polyadenylation signal elements in the coupling of polyadenylation and last-intron removal. Mol. Cell. Biol., 1999, 19, 4971-4979.
    • (1999) Mol. Cell Biol. , vol.19 , pp. 4971-4979
    • Cooke, C.1    Hans, H.2    Alwine, J.C.3
  • 128
    • 0036132667 scopus 로고    scopus 로고
    • SRm160 splicing coactivator promotes transcript 3′-end cleavage
    • McCracken, S., Lambermon, M. and Blencowe, B.J., SRm160 splicing coactivator promotes transcript 3′-end cleavage. Mol. Cell. Biol., 2002, 22, 148-160.
    • (2002) Mol. Cell Biol. , vol.22 , pp. 148-160
    • McCracken, S.1    Lambermon, M.2    Blencowe, B.J.3
  • 129
    • 0043172414 scopus 로고    scopus 로고
    • Splicing-dependent and - Independent modes of assembly for intron-encoded box C/D snoRNPs in mammalian cells
    • Hirose, T., Shu, M.D. and Steitz, J.A., Splicing-dependent and - independent modes of assembly for intron-encoded box C/D snoRNPs in mammalian cells. Mol. Cell., 2003, 12, 113-123.
    • (2003) Mol. Cell , vol.12 , pp. 113-123
    • Hirose, T.1    Shu, M.D.2    Steitz, J.A.3
  • 130
    • 0037387431 scopus 로고    scopus 로고
    • Messenger RNA surveillance and the evolutionary proliferation of introns
    • Lynch, M. and Kewalramani, A., Messenger RNA surveillance and the evolutionary proliferation of introns. Mol. Biol. Evol., 2003, 20, 563-571.
    • (2003) Mol. Biol. Evol. , vol.20 , pp. 563-571
    • Lynch, M.1    Kewalramani, A.2
  • 132
    • 0033835231 scopus 로고    scopus 로고
    • Characterization of the biochemical properties of the human Upf1 gene product that is involved in nonsense-mediated mRNA decay
    • Bhattacharya, A., Czaplinski, K., Trifillis, P., He, F., Jacobson, A. and Peltz, S.W., Characterization of the biochemical properties of the human Upf1 gene product that is involved in nonsense-mediated mRNA decay. RNA, 2000, 6, 1226-1235.
    • (2000) RNA , vol.6 , pp. 1226-1235
    • Bhattacharya, A.1    Czaplinski, K.2    Trifillis, P.3    He, F.4    Jacobson, A.5    Peltz, S.W.6
  • 133
    • 0035038083 scopus 로고    scopus 로고
    • Evidence that phosphorylation of human Upf1 protein varies with intracellular location and is mediated by a wortmannin-sensitive and rapamycin-sensitive P1 3-kinase-related kinase signaling pathway
    • Pal, M., Ishigaki, Y., Nagy, F. and Maquat, L.E., Evidence that phosphorylation of human Upf1 protein varies with intracellular location and is mediated by a wortmannin-sensitive and rapamycin-sensitive P1 3-kinase-related kinase signaling pathway. RNA, 2001, 7, 5-15.
    • (2001) RNA , vol.7 , pp. 5-15
    • Pal, M.1    Ishigaki, Y.2    Nagy, F.3    Maquat, L.E.4
  • 134
    • 0042068262 scopus 로고    scopus 로고
    • Complexes between the nonsense-mediated mRNA decay pathway factor human Upf1 (up-frameshift protein 1 ) and essential nonsense-mediated mRNA decay factors in HeLa cells
    • Schell, T., Kocher, T., Wilm, M., Seraphin, B., Kulozik, A.E. and Hentze, M.W., Complexes between the nonsense-mediated mRNA decay pathway factor human Upf1 (up-frameshift protein 1 ) and essential nonsense-mediated mRNA decay factors in HeLa cells. Biochem. J., 2003, 373, 775-783.
    • (2003) Biochem. J. , vol.373 , pp. 775-783
    • Schell, T.1    Kocher, T.2    Wilm, M.3    Seraphin, B.4    Kulozik, A.E.5    Hentze, M.W.6
  • 135
    • 0035933889 scopus 로고    scopus 로고
    • Cloning of a novel phosphatidylinositol kinase-related kinase, characterization of the human SMG-1 RNA surveillance protein
    • Denning, G., Jamieson, L., Maquat, L.E., Thompson, E.A. and Fields, A.P., Cloning of a novel phosphatidylinositol kinase-related kinase, characterization of the human SMG-1 RNA surveillance protein. J. Biol. Chem., 2001, 276, 22709-22714.
    • (2001) J. Biol. Chem. , vol.276 , pp. 22709-22714
    • Denning, G.1    Jamieson, L.2    Maquat, L.E.3    Thompson, E.A.4    Fields, A.P.5
  • 136
    • 0035449691 scopus 로고    scopus 로고
    • Human SMG-1, a novel phosphatidylinositol 3-kinase-related protein kinase, associates with components of the mRNA surveillance complex and is involved in the regulation of nonsense-mediated mRNA decay
    • Yamashita, A., Ohnishi, T., Kashima, I., Tava, Y. and Ohno, S., Human SMG-1, a novel phosphatidylinositol 3-kinase-related protein kinase, associates with components of the mRNA surveillance complex and is involved in the regulation of nonsense-mediated mRNA decay. Genes Dev., 2001, 15, 2215-2228.
    • (2001) Genes Dev. , vol.15 , pp. 2215-2228
    • Yamashita, A.1    Ohnishi, T.2    Kashima, I.3    Tava, Y.4    Ohno, S.5
  • 137
    • 0037279012 scopus 로고    scopus 로고
    • Characterization of human Smg5/7a, a protein with similarities to Caenorhabditis elegans SMG5 and SMG7 that functions in the dephosphorylation of Upf1
    • Chiu, S.Y., Serin, G., Ohara, O. and Maquat, L.E., Characterization of human Smg5/7a, a protein with similarities to Caenorhabditis elegans SMG5 and SMG7 that functions in the dephosphorylation of Upf1. RNA, 2003, 9, 77-87.
    • (2003) RNA , vol.9 , pp. 77-87
    • Chiu, S.Y.1    Serin, G.2    Ohara, O.3    Maquat, L.E.4
  • 138
    • 0037099212 scopus 로고    scopus 로고
    • NASty effects on fibrillin pre-mRNA splicing, another case of ESE does it, but proposals for translation-dependent splice site choice live on
    • Maquat, L.E., NASty effects on fibrillin pre-mRNA splicing, another case of ESE does it, but proposals for translation-dependent splice site choice live on. Genes Dev., 2002, 16, 1743-1753.
    • (2002) Genes Dev. , vol.16 , pp. 1743-1753
    • Maquat, L.E.1
  • 139
    • 0030034421 scopus 로고    scopus 로고
    • A pre-mRNA-binding protein accompanies the RNA from the gene through the nuclear pores and into polysomes
    • Visa, N., Alzhanova-Ericsson, A.T., Sun, X., Kiseleva, E., Bjorkroth, B., Wurtz, T. and Daneholt, B., A pre-mRNA-binding protein accompanies the RNA from the gene through the nuclear pores and into polysomes. Cell, 1996, 84, 253-264.
    • (1996) Cell , vol.84 , pp. 253-264
    • Visa, N.1    Alzhanova-Ericsson, A.T.2    Sun, X.3    Kiseleva, E.4    Bjorkroth, B.5    Wurtz, T.6    Daneholt, B.7
  • 140
    • 0037275978 scopus 로고    scopus 로고
    • Nuclear translation, what is the evidence?
    • Dahlberg, J.E., Lund, E. and Goodwin, E.B., Nuclear translation, what is the evidence? RNA, 2003, 9, 1-8.
    • (2003) RNA , vol.9 , pp. 1-8
    • Dahlberg, J.E.1    Lund, E.2    Goodwin, E.B.3
  • 141
    • 0030745114 scopus 로고    scopus 로고
    • Cloning and characterization of HUPF1, a human homolog of the Saccharomyces cerevisiae nonsense mRNA-reducing UPF1 protein
    • Applequist, S.E., Selg, M., Raman, C. and Jack, H.M., Cloning and characterization of HUPF1, a human homolog of the Saccharomyces cerevisiae nonsense mRNA-reducing UPF1 protein. Nucleic Acids Res., 1997, 25, 814-821.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 814-821
    • Applequist, S.E.1    Selg, M.2    Raman, C.3    Jack, H.M.4
  • 142
    • 0035787913 scopus 로고    scopus 로고
    • Nonsense-mediated mRNA decay, insights into mechanism front the cellular abundance of human Upf1, Upf2, Upf3, and Upf3X proteins
    • Maquat, L.E. and Serin, G., Nonsense-mediated mRNA decay, insights into mechanism front the cellular abundance of human Upf1, Upf2, Upf3, and Upf3X proteins. Cold Spring Harb. Symp. Quant. Biol., 2001, 66, 313-320.
    • (2001) Cold Spring Harb. Symp. Quant. Biol. , vol.66 , pp. 313-320
    • Maquat, L.E.1    Serin, G.2
  • 143
    • 0037025175 scopus 로고    scopus 로고
    • Alternatively spliced TCR mRNA induced by disruption of reading frame
    • Wang, J., Hamilton, J.I., Carter, M.S., Li, S. and Wilkinson, M.F., Alternatively spliced TCR mRNA induced by disruption of reading frame. Science, 2002, 297, 108-110.
    • (2002) Science , vol.297 , pp. 108-110
    • Wang, J.1    Hamilton, J.I.2    Carter, M.S.3    Li, S.4    Wilkinson, M.F.5
  • 144
    • 0037080771 scopus 로고    scopus 로고
    • T-cell receptor sequences that elicit strong down-regulation of premature termination codon-bearing transcripts
    • Gudikote, J.P. and Wilkinson, M.F., T-cell receptor sequences that elicit strong down-regulation of premature termination codon-bearing transcripts. EMBO J., 2002, 21, 125-134.
    • (2002) EMBO J. , vol.21 , pp. 125-134
    • Gudikote, J.P.1    Wilkinson, M.F.2
  • 145
    • 0034667531 scopus 로고    scopus 로고
    • Nonsense mutations in the human β-globin gene lead to unexpected levels of cytoplasmic mRNA accumulation
    • Romao, L., Inacio, A., Santos, S., Avila, M., Faustino, P., Pacheco, P. and Lavinha, J., Nonsense mutations in the human β-globin gene lead to unexpected levels of cytoplasmic mRNA accumulation. Blood, 2000, 96, 2895-2901.
    • (2000) Blood , vol.96 , pp. 2895-2901
    • Romao, L.1    Inacio, A.2    Santos, S.3    Avila, M.4    Faustino, P.5    Pacheco, P.6    Lavinha, J.7
  • 146
    • 0036493774 scopus 로고    scopus 로고
    • Abnormally spliced β-globin mRNAs, a single point mutation generates transcripts sensitive and insensitive to nonsense-mediated mRNA decay
    • Danckwardt, S., Neu-Yilik, G., Thermann, R., Frede, U., Hentze, M.W. and Kulozik, A.E., Abnormally spliced β-globin mRNAs, a single point mutation generates transcripts sensitive and insensitive to nonsense-mediated mRNA decay. Blood, 2002, 99, 1811-1816.
    • (2002) Blood , vol.99 , pp. 1811-1816
    • Danckwardt, S.1    Neu-Yilik, G.2    Thermann, R.3    Frede, U.4    Hentze, M.W.5    Kulozik, A.E.6
  • 147
    • 0027478167 scopus 로고
    • Targeted modification of the apolipoprotein B gene results in hypobetalipoproteinemia and developmental abnormalities in mice
    • Homanics, G.E., Smith, T.J., Zhang, S.H., Lee, D., Young, S.G. and Maeda, N., Targeted modification of the apolipoprotein B gene results in hypobetalipoproteinemia and developmental abnormalities in mice. Proc. Natl. Acad. Sci. USA, 1993, 90, 2389-2393.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 2389-2393
    • Homanics, G.E.1    Smith, T.J.2    Zhang, S.H.3    Lee, D.4    Young, S.G.5    Maeda, N.6
  • 148
    • 0032545280 scopus 로고    scopus 로고
    • A gene-targeted mouse model for familial hypobetalipoproteinemia. Low levels of apolipoprotein B mRNA in association with a nonsense mutation in exon 26 of the apolipoprotein B gene
    • Kim, E., Ambroziak, P., Veniant, M.M., Hamilton, R.L. and Young, S.G., A gene-targeted mouse model for familial hypobetalipoproteinemia. Low levels of apolipoprotein B mRNA in association with a nonsense mutation in exon 26 of the apolipoprotein B gene. J. Biol. Chem., 1998, 273, 33977-33984.
    • (1998) J. Biol. Chem. , vol.273 , pp. 33977-33984
    • Kim, E.1    Ambroziak, P.2    Veniant, M.M.3    Hamilton, R.L.4    Young, S.G.5
  • 149
    • 0036888905 scopus 로고    scopus 로고
    • Identification of a human decapping complex associated with hUpf proteins in nonsense-mediated decay
    • Lykke-Andersen, J., Identification of a human decapping complex associated with hUpf proteins in nonsense-mediated decay. Mol. Cell. Biol., 2002, 22, 8114-8121.
    • (2002) Mol. Cell Biol. , vol.22 , pp. 8114-8121
    • Lykke-Andersen, J.1
  • 150
    • 0038112021 scopus 로고    scopus 로고
    • Rapid deadenylation triggered by a nonsense codon precedes decay of the RNA body in a mammalian cytoplasmic nonsense-mediated decay pathway
    • Chen, C.Y. and Shyu, A.B., Rapid deadenylation triggered by a nonsense codon precedes decay of the RNA body in a mammalian cytoplasmic nonsense-mediated decay pathway. Mol. Cell. Biol., 2003, 23, 4805-4813.
    • (2003) Mol. Cell Biol. , vol.23 , pp. 4805-4813
    • Chen, C.Y.1    Shyu, A.B.2
  • 151
    • 0036909093 scopus 로고    scopus 로고
    • The human LSm1-7 proteins colocalize with the mRNA-degrading enzymes Dcp1/2 and Xrnl in distinct cytoplasmic foci
    • Ingelfinger, D., Arndt-Jovin, D.J., Luhrmann, R. and Achsel, T., The human LSm1-7 proteins colocalize with the mRNA-degrading enzymes Dcp1/2 and Xrnl in distinct cytoplasmic foci. RNA, 2002, 8, 1489-1501.
    • (2002) RNA , vol.8 , pp. 1489-1501
    • Ingelfinger, D.1    Arndt-Jovin, D.J.2    Luhrmann, R.3    Achsel, T.4
  • 152
    • 0037121926 scopus 로고    scopus 로고
    • Human Dcp2, a catalytically active mRNA decapping enzyme located in specific cytoplasmic structures
    • Van Dijk, E., Cougot, N., Meyer, S., Babajko, S., Wahle, E. and Seraphin, B., Human Dcp2, a catalytically active mRNA decapping enzyme located in specific cytoplasmic structures. EMBO J., 2002, 21, 6915-6924.
    • (2002) EMBO J. , vol.21 , pp. 6915-6924
    • Van Dijk, E.1    Cougot, N.2    Meyer, S.3    Babajko, S.4    Wahle, E.5    Seraphin, B.6
  • 153
    • 0024443107 scopus 로고
    • Novel metabolism of several β°-thalassemic β-globin mRNAs in the erythroid tissues of transgenic mice
    • Lim, S., Mullins, J.J. Chen, C.M., Gross, K.W. and Maquat, L.E., Novel metabolism of several β°-thalassemic β-globin mRNAs in the erythroid tissues of transgenic mice. EMBO J., 1989, 87 2613-2619.
    • (1989) EMBO J. , vol.87 , pp. 2613-2619
    • Lim, S.1    Mullins, J.J.2    Chen, C.M.3    Gross, K.W.4    Maquat, L.E.5
  • 154
    • 0026641165 scopus 로고
    • Human β-globin mRNAs that harbor a nonsense codon are degraded in murine erythroid tissues to intermediates lacking regions of exon I or exons I and II that have a cap-like structure at the 5′ termini
    • Lim, S.K. and Maquat, L.E., Human β-globin mRNAs that harbor a nonsense codon are degraded in murine erythroid tissues to intermediates lacking regions of exon I or exons I and II that have a cap-like structure at the 5′ termini. EMBO J., 1992, 11, 3271-3278.
    • (1992) EMBO J. , vol.11 , pp. 3271-3278
    • Lim, S.K.1    Maquat, L.E.2
  • 155
    • 0026583873 scopus 로고
    • Nonsense codons in human β-globin mRNA result in the production of mRNA degradation products
    • Lim, S.K., Sigmund, C.D., Gross, K.M. and Maquat, L.E., Nonsense codons in human β-globin mRNA result in the production of mRNA degradation products. Mol. Cell. Biol., 1992, 12, 1149-1161.
    • (1992) Mol. Cell Biol. , vol.12 , pp. 1149-1161
    • Lim, S.K.1    Sigmund, C.D.2    Gross, K.M.3    Maquat, L.E.4
  • 156
    • 0036790995 scopus 로고    scopus 로고
    • β°-Globin mRNA decay in erythroid cells, UG site-preferred endonucleolytic cleavage that is augmented by a premature termination codon
    • Stevens, A., Wang, Y., Bremer, K., Zhang, J., Hoepfner, R., Antoniou, M., Schoenberg, D.R. and Maquat, L.E., β°-Globin mRNA decay in erythroid cells, UG site-preferred endonucleolytic cleavage that is augmented by a premature termination codon. Proc. Natl. Acad. Sci. USA, 2002, 99, 12741-12746.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 12741-12746
    • Stevens, A.1    Wang, Y.2    Bremer, K.3    Zhang, J.4    Hoepfner, R.5    Antoniou, M.6    Schoenberg, D.R.7    Maquat, L.E.8
  • 157
    • 0041832086 scopus 로고    scopus 로고
    • An endonuclease activity similar to Xenopus PMR1 catalyzes the degradation of normal and nonsense-containing human β-globin mRNA in erythroid cells
    • Bremer, K.A., Stevens, A. and Schoenberg, D.R., An endonuclease activity similar to Xenopus PMR1 catalyzes the degradation of normal and nonsense-containing human β-globin mRNA in erythroid cells. RNA, 2003, 9, 1157-1167.
    • (2003) RNA , vol.9 , pp. 1157-1167
    • Bremer, K.A.1    Stevens, A.2    Schoenberg, D.R.3
  • 158
    • 0026315967 scopus 로고
    • Nonsense codons within the Rous sarcoma virus gag gene decrease the stability of unspliced viral RNA
    • Barker, G.F. and Beemon, K., Nonsense codons within the Rous sarcoma virus gag gene decrease the stability of unspliced viral RNA. Mol. Cell. Biol., 1991, 11, 2760-2768.
    • (1991) Mol. Cell Biol. , vol.11 , pp. 2760-2768
    • Barker, G.F.1    Beemon, K.2
  • 159
    • 0028210434 scopus 로고
    • Rous sarcoma virus RNA stability requires an open reading frame in the gag gene and sequences downstream of the gag-pol junction
    • Barker, G.F. and Beemon, K., Rous sarcoma virus RNA stability requires an open reading frame in the gag gene and sequences downstream of the gag-pol junction. Mol. Cell. Biol., 1994, 14, 1986-1996.
    • (1994) Mol. Cell Biol. , vol.14 , pp. 1986-1996
    • Barker, G.F.1    Beemon, K.2
  • 160
    • 0028205660 scopus 로고
    • Frameshift mutations in the v-src gene of avian sarcoma virus act in cis to specifically reduce v-src mRNA levels
    • Simpson, S.B. and Stoltzfus, C.M., Frameshift mutations in the v-src gene of avian sarcoma virus act in cis to specifically reduce v-src mRNA levels. Mol. Cell. Biol., 1994, 14, 1835-1844.
    • (1994) Mol. Cell Biol. , vol.14 , pp. 1835-1844
    • Simpson, S.B.1    Stoltzfus, C.M.2


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