PCR-SSCP Analysis of p53 Gene in Human Primary Brain Tumor

Journal of West China University of Medical Sciences

Volumn 28, Issue 1, 1997, Pages 45-49

  Tan, Deyong ^a   Sun, Zhilin ^a  

^a SCHOOL OF BASIC MEDICAL SCIENCES   (China)

Author keywords

Human primary brain tumor; P53 gene; Pcr sscp analysis

Indexed keywords

ARTICLE; ASTROCYTOMA; BRAIN TUMOR; EXON; GENETICS; GLIOBLASTOMA; HUMAN; MENINGIOMA; POINT MUTATION; POLYMERASE CHAIN REACTION; SINGLE STRAND CONFORMATION POLYMORPHISM; TUMOR SUPPRESSOR GENE;

ASTROCYTOMA; BRAIN NEOPLASMS; EXONS; GENES, P53; GLIOBLASTOMA; HUMANS; MENINGEAL NEOPLASMS; MENINGIOMA; POINT MUTATION; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL;

EID: 1842680843     PISSN: 02577712     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. Baker SJ, Markowitz S, Fearon ER, et al. Suppression of human colorectal carcinoma cell growth by wild-typy p53. Science, 1990; 249 : 912
2. Diller L, Kassel J, Nelson CE, et al. p53 function as a cell cycle contol portein in osteosarcomas. Mol Cell Biol, 1990; 10 : 5772
3. Xiong Y, Hannon GJ, Zhang H, et al. p21 is a universal inhibitor of cyclin Kinases. Nature, 1993; 366 : 701
4. Cheng J, Hass M. Frequent mutations in the p53 tumor suppressor gene in human leukemia t-cell liness. Mol Cell Biol. 1990; 10 : 5502
5. Baker SJ, Fearon ER, Nigro JM, et al. Chromosome 17 detection and p53 gene mutations in colorectal carcinomas. Science, 1989; 244 : 217
6. Hus I C, Metcalf R A, et al. Mutation hostspot in the p53 gene in human hepatocellular carcinomas. Nature, 1991; 350 : 427
7. Malkin D, Li FD, Strong LC, et al. Germ line p53 mutation in a familial syndrome of breast cancer, sarcoma, and other neoplaems. Science, 1990; 250 : 1233
8. Srivastava S, Zou Z, Pirollo K, et al. Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-fraumeni syndrome. Nature, 1990; 348 : 747
9. Sidranasky D, Mikkelson T, Schwechhemar K, et al. Clonal expenssion of p53 mutaut cells is associated with brain tumor propression. Nature, 1992; 355 : 846
10. Orita M, Iwahana H, Kanazana H, et al. Detection of polymorphisms of hum an DNA by gel electrophoresis as a single-strand conformation polymorophisms. Proc Natl Acad USA, 1989; 86 : 2766
11. Sambrook J, Fritsch EF, Maniatis T, et al. Molecular Cloning A Laboratory Manual. Second eidition. New York; Cold Spring Harbor Laboratory Press, 1989; 1.33-1.34, 1.38-1.41
12. Levine AL, Monand J, Finly CA, et al. The P53 tumor suppressor gene. Nature, 1991; 351 : 453