The Prozone Phenomenon in Syphilis Testing

Southern Medical Journal

Volumn 97, Issue 4, 2004, Pages 327-328

  Geisler, William M ^a  

^a University of Alabama at Birmingham   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARDIOLIPIN; CD4 ANTIGEN; CHARCOAL;

ANTIBODY DETECTION; B LYMPHOCYTE; CELL COUNT; CEREBROSPINAL FLUID ANALYSIS; EDITORIAL; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOCCULATION; HIGH RISK POPULATION; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFECTION CONTROL; LABORATORY TEST; NEUROSYPHILIS; REAGIN TEST; SCREENING TEST; SEROLOGY; SEXUAL BEHAVIOR; SYPHILIS; VIRUS DETECTION; VIRUS TRANSMISSION;

FALSE NEGATIVE REACTIONS; HUMANS; SYPHILIS; SYPHILIS SERODIAGNOSIS;

EID: 1842680814     PISSN: 00384348     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.SMJ.0000092571.52330.13     Document Type: Editorial

References (7)

1. Centers for Disease Control and Prevention, Division of STD Prevention. Sexually Transmitted Disease Surveillance 2001 Supplement: Syphilis Surveillance Report. Atlanta, Centers for Disease Control and Prevention, Feb 2003. Available at http://www.cdc.gov/std/Syphilis2001/ 2001SyphSuppText.pdf. Accessed August 12, 2003.
2. Smith G, Holman RP. The prozone phenomenon with syphilis and HIV-1 co-infection. South Med J 2004;97:379-382.
3. el-Zaatari MM, Martens MG, Anderson GD. Incidence of the prozone phenomenon in syphilis serology. Obstet Gynecol 1994;84:609-612.
4. Jurado RL, Campbell J, Martin PD. Prozone phenomenon in secondary syphilis: has its time arrived? Arch Intern Med 1993; 153:2496-2498.
5. Uribe CS, Garcia FA. Neurosyphilis and the prozone effect [in Spanish]. Rev Neurol 1998;27:970-972.
6. Berkowitz K, Baxi L, Fox HE. False-negative syphilis screening: the prozone phenomenon, nonimmune hydrops, and diagnosis of syphilis during pregnancy. Am J Obstet Gynecol 1990;163:975-977.
7. Imrie A, Best S, Penny R, et al. False-negative ELISA result for HIV antibody due to an apparent prozone phenomenon. Med J Aust 1987; 147:42 (letter).