2,3-Diarylpyran-4-ones: A new series of selective cyclooxygenase-2 inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 9, 2004, Pages 2195-2198

  Joo, Yung Hyup ^a   Kim, Jin Kwan ^a   Kang, Seon Hwa ^a   Noh, Min Soo ^a   Ha, Jun Yong ^a   Choi, Jin Kyu ^a   Lim, Kyung Min ^a   Chung, Shin ^a  

^a AmorePacific Corporation   (South Korea)

Author keywords

Benzopyran; Cyclooxygenase 2; Pyrone

Indexed keywords

4 PYRONE DERIVATIVE; CELECOXIB; CYCLOOXYGENASE 2 INHIBITOR; INDOMETACIN; KETONE DERIVATIVE; PROSTAGLANDIN SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ABSORPTION; DRUG ACTIVITY; DRUG BIOAVAILABILITY; DRUG HALF LIFE; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; IC 50; IN VITRO STUDY; MALE; NONHUMAN; PHYSICAL CHEMISTRY; RAT; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

ANIMALS; CYCLOOXYGENASE INHIBITORS; MALE; PYRANS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 1842639615     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.02.028     Document Type: Article

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