Inhibition of Transient K+ Current by Copper in Drosophila Neurons

Neurochemical Research

Volumn 29, Issue 4, 2004, Pages 785-789

  Alshuaib, Waleed B ^a   Mathew, Mini V ^a  

^a KUWAIT UNIVERSITY   (Kuwait)

Author keywords

Copper; Neurotoxic; Patch clamp; Potassium

Indexed keywords

4 AMINOPYRIDINE; COPPER; SODIUM CHLORIDE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DROSOPHILA; ELECTROPHYSIOLOGY; EMBRYO; NERVE CELL; NERVE CELL EXCITABILITY; NERVE CELL MEMBRANE POTENTIAL; NONHUMAN; PATCH CLAMP; POTASSIUM CURRENT; PRIORITY JOURNAL;

4-AMINOPYRIDINE; ANIMALS; COPPER; DROSOPHILA; NEURONS; POTASSIUM CHANNEL BLOCKERS;

ANIMALIA; INSECTA;

EID: 1842611828     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:NERE.0000018851.62617.36     Document Type: Article

References (21)

1. 2+ in rat brain regions. Can. J. Biochem. 51:87-92.
2. Ono, S., and Cherian, M. G. 1999. Regional distribution of metallothionein, zinc, and copper in the brain of different strains of rats. Biol. Trace Elem. Res. 69:151-159.
3. Friedman, B., and Price, J. L. 1984. Fiber systems in the olfactory bulb and cortex: A study in adult and developing rats, using the Timm method with the light and electron microscope. J. Comp. Neurol. 223:88-109.
4. Sato, M., Ohtomo, K., Daimon, T., Sugiyama, T., and Iijima, K. 1994. Localization of copper to afferent terminals in rat locus ceruleus, in contrast to mitochondrial copper in cerebellum. J. Histochem. Cytochem. 42:1585-1591.
5. Hartter, D. E., and Barnea, A. 1988. Evidence for release of copper in the brain: Depolarization-induced release of newly taken-up 67 copper. Synapse 2:412-415.
6. Kardos, J., Kovacs, I., Hajos, F., Kalman, M., and Simonyi, M. 1989. Nerve endings from rat brain tissue release copper upon depolarization: A possible role in regulating neuronal excitability. Neurosci. Lett. 103:139-144.
7. Schoppa, N. E., and Westbrook, G. L. 1999. Regulation of synaptic timing in the olfactory bulb by an A-type potassium current. Nat. Neurosci. 2:1106-1113.
8. Horning, M. S., and Trombley, P. O. 2001. Zinc and copper influence excitability of rat olfactory bulb neurons by multiple mechanisms. J. Neurophysiol. 86:1652-1660.
9. Pinnock, R. D., David, J. A., and Sattelle, D. B. 1988. Ionic events following GABA receptor activation in an identified insect motor neuron. Proc. R. Soc. Lond. B Biol. Sci. 232:457-470.
10. Ferreira, K. T. 1978. The effect of copper on frog skin: The role of sulphydryl groups. Biochim. Biophys. Acta 510:298-304.
11. Salvaterra, P. M., Boumias-Vardiabasis, N., Nair, T., Hou, G., and Lieu, C. 1987. In vitro neuronal differentiation of Drosophila embryo cells. J. Neurosci. 7:10-22.
12. Hamill, O. P., Marty, A., Neher, E., Sakman, B., and Sigworth, F. J. 1981. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflugers Arch. 391:85-100.
13. Corey, D. P., and Stevens, C. F. 1983. Science and technology of patch-recording electrodes. Pages 53-68, in Sakmann, B., and Neher, E. (eds.), Single-Channel Recording. Plenum, New York.
14. Alshuaib, W. B., and Byerly, L. 1996. Modulation of membrane currents by cyclic AMP in cleavage-arrested Drosophila neurons. J. Exp. Biol. 199:537-548.
15. Alshuaib, W. B., and Mathew, M. V. 1998. Potassium current in Drosophila neurons is increased by either dunce mutation or cyclic AMP. J. Neurosci. Res. 52:521-529.
16. Alshuaib, W. B., Hasan, S. M., Cherian, S. P., Mathew, M. V., Fahim, M. A., and Hasan, M. Y. 2001. Reduced potassium currents in old rat CA1 hippocampal neurons. J. Neurosci. Res. 63:176-184.
17. LeMasson, G., Marder, E., and Abbott, L. F. 1993. Activity-dependent regulation of conductances in model neurons. Science. 259:1915-1917.
18. Mayer, M. L., and Sugiyama, K. 1988. A modulatory action of divalent cations on transient outward current in cultured rat sensory neurons. J. Physiol. (Lond). 396:417-433.
19. Byerly, L., and Leung, H.-T. 1988. Ionic currents of Drosophila neurons in embryonic cultures. J. Neurosci. 8:4379-4393.
20. 3+. J. Neurophysiol. 71:1491-1497.
21. Sah, P., and McLachlan, E. M. 1992. Potassium currents contributing to action potential repolarization and the afterhyper-polarization in rat vagal motoneurons. J. Neurophysiol. 68:1834-1841.