Density of spinal anaesthetic solutions of bupivacaine, levobupivacaine, and ropivacaine with and without dextrose

British Journal of Anaesthesia

Volumn 92, Issue 4, 2004, Pages 547-551

  McLeod, G A ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Anaesthetic solutions, density; Anaesthetic techniques, intrathecal; Anaesthetics local, bupivacaine; Anaesthetics local, levobupivacaine; Anaesthetics local, ropivacaine; Physics, baricity

Indexed keywords

BUPIVACAINE; ELECTROLYTE; GLUCOSE; LEVOBUPIVACAINE; LOCAL ANESTHETIC AGENT; ROPIVACAINE; AMIDE; DRUG DERIVATIVE;

ACCURACY; ARTICLE; CLINICAL STUDY; CLINICAL TRIAL; CONCENTRATION RESPONSE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; COVARIANCE; DENSITY; DOUBLE BLIND PROCEDURE; DRUG SOLUTION; HUMAN; HYPOBARISM; LINEAR SYSTEM; MEASUREMENT; METHODOLOGY; OSCILLATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SAMPLING; STATISTICAL ANALYSIS; TEMPERATURE MEASUREMENT; CHEMISTRY; NERVE BLOCK; SOLUTION AND SOLUBILITY; SPINAL ANESTHESIA; TEMPERATURE;

AMIDES; ANESTHESIA, SPINAL; ANESTHETICS, LOCAL; BUPIVACAINE; ELECTROLYTES; GLUCOSE; NERVE BLOCK; SOLUTIONS; TEMPERATURE;

EID: 1842611739     PISSN: 00070912     EISSN: None     Source Type: Journal    
DOI: 10.1093/bja/aeh094     Document Type: Article

References (15)

1. Greene NM. Distribution of local anesthetic solutions within the subarachnoid space. Anesth Analg 1985; 64: 715-30
2. Stienstra R, Gielen M, Kroon JW, Van Poorten F. The influence of temperature and speed of injection on the distribution of a solution containing bupivacaine and methylene blue in a spinal canal model. Reg Anesth 1990; 15: 6-11
3. Connolly C, Wildsmith JA. Intrathecal drug spread. Can J Anaesth 1998; 45: 289-92
4. Richardson MG, Wissler RN. Density of lumbar cerebrospinal fluid in pregnant and nonpregnant humans. Anesthesiology 1996; 85: 326-30
5. Lui AC, Polis TZ, Cicutti NJ. Densities of cerebrospinal fluid and spinal anaesthetic solutions in surgical patients at body temperature. Can J Anaesth 1998; 45: 297-303
6. Logan MR, McClure JH, Wildsmith JA. Plain bupivacaine: An unpredictable spinal anaesthetic agent. Br J Anaesth 1986; 58: 292-6
7. Sanderson P, Read J, Littlewood DG, McKeown D, Wildsmith JA. Interaction between baricity (glucose concentration) and other factors influencing intrathecal drug spread. Br J Anaesth 1994; 73: 744-6
8. Wahl A, Eberli FR, Thomson DA, Luginbuhl M. Coronary artery spasm and non-Q-wave myocardial infarction following intravenous ephedrine in two healthy women under spinal anaesthesia. Br J Anaesth 2002; 89: 519-23
9. Kooger Infante NE, Van Gessel E, Forster A, Gamulin Z. Extent of hyperbaric spinal anesthesia influences the duration of spinal block. Anesthesiology 2000; 92: 1319-23
10. Lee A, Ray D, Littlewood DG, Wildsmith JA. Effect of dextrose concentration on the intrathecal spread of amethocaine. Br J Anaesth 1988; 61: 135-8
11. -1. Br J Anaesth 2001; 86: 805-7
12. -1. Br J Anaesth 2001; 86: 241-4
13. Hare GM, Ngan JC. Density determination of local anaesthetic opioid mixtures for spinal anaesthesia. Can J Anaesth 1998; 45: 341-6
14. Hallworth SP, Fernando R, Stocks GM. Predicting the density of bupivacaine and bupivacaine-opioid combinations. Anesth Analg 2002; 94: 1621-4
15. Carpenter RL, Hogan QH, Liu SS, Crane B, Moore J. Lumbosacral cerebrospinal fluid volume is the primary determinant of sensory block extent and duration during spinal anesthesia. Anesthesiology 1998; 89: 24-9