Application of Gene Expression Profiling for Validating Models of Human Breast Cancer

Toxicologic Pathology

Volumn 32, Issue SUPPL. 1, 2004, Pages 84-89

  Green, Jeffrey E ^a,b   Desai, Kartiki V ^a   Ye, Yumei ^a   Kavanaugh, Claudine ^a   Calvo, Alfonso ^a   Huh, Jung Im ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Animal models; Gene expression profiling; Mammary cancer; Microarray; Oncogenes; Transgenic mice

Indexed keywords

ANIMAL MODEL; ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; CANCER CLASSIFICATION; CANCER MODEL; CANCER RESEARCH; CANCER THERAPY; DNA MICROARRAY; EXPERIMENTAL MEDICINE; GENE EXPRESSION PROFILING; GENE IDENTIFICATION; GENETIC DIFFERENCE; GENETIC SIMILARITY; GENOMICS; HUMAN; NONHUMAN; ONCOGENE; PRECLINICAL TESTING; PRIORITY JOURNAL; SPECIES DIFFERENCE; TRANSGENIC MOUSE; VALIDATION PROCESS;

ANIMALS; BREAST NEOPLASMS; DISEASE MODELS, ANIMAL; FEMALE; FORECASTING; GENE EXPRESSION PROFILING; GENOMICS; HUMANS; MAMMARY NEOPLASMS, ANIMAL; MICE; MICE, TRANSGENIC; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; ONCOGENES; REPRODUCIBILITY OF RESULTS;

ANIMALIA; MUS MUSCULUS; RODENTIA;

EID: 1842563088     PISSN: 01926233     EISSN: None     Source Type: Journal    
DOI: 10.1080/01926230490424897     Document Type: Article

References (21)

1. Allred, D. C., Clark, G. M., Elledge, R., Fuqua, S. A., Brown, R. W., and Chambness, G. C. (1993). Association of p53 protein expression with tumor cell proliferation rate and clinical outcome in node-negative breast cancer. J Nat Cancer Inst 85, 200-6.
2. Band, V. (1998). The role of retinoblastoma and p53 tumor supressor pathways in human mammary epithelial cell immortilization. Inter J Oncol 12(3), 499-507.
3. Berns, E. M., Foekens, J. A., van Putten, W. L., van Staveren, I. L., Portengen, H., de Konig, W. C., and Klijn, J. G. (1992). Prognostic factors in human primary breast cancer: comparison of c-myc and HER2/neu amplification. J Steroid Biochem Mol Biol 43(1-3), 13-9.
4. Coles, C., Condie, A., Chetty, U., Steel, C. M., Evans, H. J., and Prosser, J. (1992). p53 mutations in breast cancer. Cancer Res 52, 5291-8.
5. Courtneidge, S. A. (1985). Activation of the pp60c-src kinase by middle T antigen binding or by dephosphorylation. Embo J 4(6), 1471-7.
6. Desai, K. V., Kavanaugh, C. J., Calvo, A., and Green, J. E. (2002). Chipping away at breast cancer: insights from microarray studies of human and mouse mammary cancer. Endocr Relat Cancer 9(4), 207-20.
7. Desai, K. V., Xiao, N., Wang, W., Gangi, L., Greene, J., Powell, J. I., Dickson, R., Furth, P., Hunter, K., Kucherlapati, R., Simon, R., Liu, E. T., and Green, J. E. (2002). Initiating oncogenic event determines gene-expression patterns of human breast cancer models. Proc Natl Acad Sci USA 99(10), 6967-72.
8. Guy, C. T., Cardiff, R. D., and Muller, W. J. (1992). Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease. Mol Cell Biol 12(3), 954-61.
9. Kavanaugh, C. J., Desai, K. V., Calvo, A., Brown, P. H., Couldrey, C., Lubet, R., and Green, J. E. (2002). Pre-clinical applications of transgenic mouse mammary cancer models. Transgenic Res 11(6), 617-33.
10. Li, M., Hu, J., Heermeier, K., Hennighausen, L., and Furth, P. A. (1996). Expression of a viral oncoprotein during mammary gland development alters cell fate and function: induction of p53-independent apoptosis is followed by impaired milk protein production in surviving cells. Cell Growth Differ 7, 3-11.
11. Liao, D. J., and Dickson, R. B. (2000). c-Myc in breast cancer. Endocr Relat Cancer 7(3), 143-64.
12. Liu, M., Von Lintig, F., Liyanage, M., Shibata, M. A., Jorcyk, C. L., Ried, T., Boss, G. R., and Green, J. E. (1998). Amplification of Ki-ras and elevation of MAP kinase activity during mammary tumor progression in C3(1)/SV40 Tag transgenic mice. Oncogene 17, 2403-11.
13. Ludlow, J. W. (1993). Interactions between SV40 large-tumor antigen and the growth suppressor proteins pRB and p53. FASEB J 7, 866-71.
14. Maroulakou, I. G., Anver, M., Garrett, L., and Green, J. E. (1994). Prostate and mammary adenocarcinoma in transgenic mice carrying a rat C3(1) simian virus 40 large tumor antigen fusion gene. Proc Natl Acad Sci USA 91, 11236-40.
15. Mietz, J. A., Unger, T., Huibregtse, J. M., and Howley, P. M. (1992). The transcriptional transactivation function of wild-type p53 is inhibited by SV40 large T-antigen and by HPV-16 E6 oncoprotein. EMBO J 11, 5013-20.
16. Muller, W. J., Sinn, E., Pattengale, P. K., Wallace, R., and Leder, P. (1988). Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene. Cell 54(1), 105-15.
17. Rochlitz, C. F., Scott, G. K., Dodson, J. M., Liu, E., Dollbaum, C., Smith, H. S., and Benz, C. C. (1989). Incidence of activating ras oncogene mutations associated with primary and metastatic human breast cancer. Cancer Res 49(2), 357-60.
18. Sinn, E., Muller, W., Pattengale, P., Tepler, I., Wallace, R., and Leder, P. (1987). Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: synergistic action of oncogenes in vivo. Cell 49(4), 465-75.
19. Sorlie, T., Perou, C. M., Tibshirani, R., Aas, T., Geisler, S., Johnsen, H., Hastie, T., Eisen, M. B., van de Rijn, M., Jeffrey, S. S., Thorsen, T., Quist, H., Matese, J. C., Brown, P. O., Botstein, D., Eystein Lonning, P., and Borresen-Dale, A. L. (2001). Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci USA 98(19), 10869-74.
20. Stewart, T. A., Pattengale, P. K., and Leder, P. (1984). Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes. Cell 38(3), 627-37.
21. Wang, D. Z., Hammond, V. E., Abud, H. E., Bertoncello, I., McAvoy, J. W., and Bowtell, D. D. (1997). Mutation in Sos1 dominantly enhances a weak allele of the EGFR, demonstrating a requirement for Sos1 in EGFR signaling and development. Genes Dev 11(3), 309-20.