Analysis of glomerular anionic charge status in children with IgA nephropathy using confocal laser scanning microscopy

Nephron - Clinical Practice

Volumn 96, Issue 3, 2004, Pages

  Sakagami, Yoshitsugu ^a   Nakajima, Mitsuru ^a   Takagawa, Ken ^a   Ueda, Taku ^a   Akazawa, Hideki ^a   Maruhashi, Yoshiyuki ^a   Shimoyama, Hironobu ^a   Kamitsuji, Hidekazu ^b   Yoshioka, Akira ^a  

^a NARA MEDICAL UNIVERSITY   (Japan)

^b NARA MEDICAL UNIVERSITY HOSPITAL   (Japan)

Author keywords

Childhood IgA nephropathy; Confocal laser scanning microscopy; Glomerular anionic charge

Indexed keywords

FLUORESCEIN ISOTHIOCYANATE; IMMUNOGLOBULIN A; POLYLYSINE; TRACER;

ADOLESCENT; ARTICLE; BASEMENT MEMBRANE; CHILD; CLINICAL ARTICLE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; FLUORESCENCE; GLOMERULUS CAPILLARY; HUMAN; HUMAN TISSUE; IMMUNOGLOBULIN A NEPHROPATHY; KIDNEY BIOPSY; MALE; METHYLATION; PH; PRIORITY JOURNAL; PROTEINURIA; SAPONIFICATION; STAINING; STATISTICAL ANALYSIS; URINALYSIS;

ADOLESCENT; ANIONS; ANTI-GLOMERULAR BASEMENT MEMBRANE DISEASE; BASEMENT MEMBRANE; BIOPSY; CAPILLARIES; CHILD; FEMALE; FLUORESCEIN-5-ISOTHIOCYANATE; FLUORESCENCE; GLOMERULONEPHRITIS, IGA; HUMANS; KIDNEY GLOMERULUS; MALE; MICROSCOPY, CONFOCAL; POLYLYSINE; PROTEINURIA; STAINING AND LABELING; STATISTICS, NONPARAMETRIC;

EID: 1842559578     PISSN: 16602110     EISSN: None     Source Type: Journal    
DOI: 10.1159/000076747     Document Type: Article

References (23)

1. Bartosik LP, Lajoie G, Sugar L, Cattran DC: Predicting progression in IgA nephropathy. Am J Kidney Dis 2001;38:728-735.
2. D'Amico G: Natural history of idiopathic IgA nephropathy: Role of clinical and histological prognostic factors. Am J Kidney Dis 2000;36:227-237.
3. Mera J, Uchida S, Nagase M: Clinicopathologic study on prognostic markers in IgA nephropathy. Nephron 2000;84:148-157.
4. Brenner BM, Hostetter TH, Humes HD: Molecular basis of proteinuria of glomerular origin. N Engl J Med 1978;298:826-833.
5. Rennke HG, Patel Y, Venkatachalam MA: Glomerular filtration of proteins: Clearance of anionic, neutral, and cationic horseradish peroxidase in the rat. Kidney Int 1978;13:278-288.
6. Carrie BJ, Salyer WR, Myers BD: Minimal change nephropathy: An electrochemical disorder of the glomerular membrane. Am J Med 1981;70:262-268.
7. Kitano Y, Yoshikawa N, Nakamura H: Glomerular anionic sites in minimal change nephrotic syndrome and focal segmental glomerulosclerosis. Clin Nephrol 1993;40:199-204.
8. Sakagami Y, Nakajima M, Ueda T, Akazawa H, Maruhashi Y, Shimoyama H, Takagawa K, Kamitsuji H, Yoshioka A: Analysis of glomerular anionic charge status in renal biopsy specimens of childhood minimal change nephrotic syndrome using confocal laser scanning microscopy. Jpn J Nephrol 2000;42:16-23.
9. Okada K, Kawakami K, Yano I, Funai M, Kagami S, Kuroda Y, Oite T: Ultrastructural alterations of glomerular anionic sites in IgA nephropathy. Clin Nephrol 1989;31:96-102.
10. Tomino Y, Yagame M, Eguchi K, Miyazaki M, Nomoto Y, Sakai H, Shirato I, Ito K: Detection of anionic sites and immunoglobulin A deposits in the glomerular capillary walls from patients with IgA nephropathy. J Clin Lab Anal 1989;3:101-107.
11. Wan LL, Hiromura K, Tsukada Y, Yano S, Naruse T: Quantitation of proteinuria in patients with IgA nephropathy and membranous nephropathy in early morning and spot urine specimens. Nephron 1996;72:369-370.
12. Andreoli SP, Yum MN, Bergstein JM: IgA nephropathy in children: Significance of glomerular basement membrane deposition of IgA. Am J Nephrol 1986;6:28-33.
13. Spicer SS: A correlative study of the histochemical properties of rodent acid mucopolysaccharides. J Histochem Cytochem 1960;8:18-35.
14. Thomaneck U, Vienken J, Waldschlager U, Diamantoglou M, Schutt W, Falkenhagen D, Klinkmann H: Detection of charges and their distribution on dialysis membranes with cationic/anionic dyes using confocal laser scanning microscopy. Int J Artif Organs 1991;14:686-690.
15. Pendland JC, Boucias DG: Physicochemical properties of cell surfaces from the different developmental stages of the entomopathogenic hyphomycete, Nomuraea rileyi. Mycologia 1991;83:264-272.
16. Tryggvason K, Wartiovaara J: Molecular basis of glomerular permselectivity. Curr Opin Nephrol Hypertens 2001;10:543-549.
17. Blouch K, Deen WM, Fauvel JP, Bialek J, Derby G, Myers BD: Molecular configuration and glomerular size selectivity in healthy and nephrotic humans. Am J Physiol 1997;273:430-437.
18. Myers BD, Guasch A: Mechanisms of proteinuria in nephrotic humans. Pediatr Nephrol 1994;8:107-112.
19. Goode NP, Shires M, Crellin DM, Davison AM: Detection of glomerular anionic sites in post-embedded ultra-thin sections using cationic colloidal gold. J Histochem Cytochem 1991;39:965-972.
20. Blau EB, Haas JE: Glomerular sialic acid and proteinuria in human renal disease. Lab Invest 1973;28:477-481.
21. Groffen AJ, Veerkamp JH, Monnens LA, van den Heuvel LP: Recent insights into the structure and functions of heparan sulfate proteoglycans in the human glomerular basement membrane. Nephrol Dial Transplant 1999;14:2119-2129.
22. 1-acid glycoprotein on aminonucleoside-induced minimal change nephrosis in rats. Nephron 1999;81:194-199.
23. Dekan G, Gabel C, Farquhar MG: Sulfate contributes to the negative charge of podocalyxin, the major sialoglycoprotein of the glomerular filtration slits. Proc Natl Acad Sci USA 1991;88:5398-5402.