Is the mitral valve passive flap theory overstated? An active valve is hypothesized

Medical Hypotheses

Volumn 62, Issue 4, 2004, Pages 605-611

  Williams, T H ^a   Jew, J Y ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACCURACY; ARTICLE; EVIDENCE BASED MEDICINE; HEART INNERVATION; HEART MUSCLE CELL; HEART MYXOMA; HYPOTHESIS; IN VITRO STUDY; LABORATORY; MITRAL VALVE; MITRAL VALVE PROLAPSE; MOTOR NERVE; MOVEMENT (PHYSIOLOGY); MUSCLE ATROPHY; NONHUMAN; PRIORITY JOURNAL; SENSORY NERVE; SMOOTH MUSCLE FIBER; THEORY; VALIDATION PROCESS;

ANIMALIA; PHOCIDAE;

EID: 1842557725     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mehy.2003.12.001     Document Type: Article

References (43)

1. Guyton AC, Hall JE. Textbook of medical physiology. 10th ed. Philadelphia: Saunders; 2000.
2. Priola DV, Fulton RL, Napolitano LM, Cooper T. Electrical activity of the canine mitral valve in situ. Am J Physiol 1969;216:238-43.
3. Little RC. Physiological basis for mitral valve function. In: Boudoulas H, Wooley CF, editors. Mitral valve prolapse and the mitral valve prolapse syndrome. Mount Kisco, NY: Futura Publishing Co., Inc.; 1988. p. 67-88.
4. Cabot RC. In: Facts on the heart. Philadelphia and London: W.B. Saunders; 1926. p. 290-5.
5. Edmunds Jr LH. Evolution of prosthetic heart valves. Am Heart J 2001;141:849-55.
6. Sapirstein JS, Smith PK. The "ideal" replacement heart valve. Am Heart J 2001;141:856-60.
7. Bloom W, Fawcett DW. Cardiac valves. In: Dreibelbis D, editor. A textbook of histology. Philadelphia: W.B. Saunders Company; 1986. p. 398-9.
8. De Biasi S, Vitellaro-Zuccarello L, Blum I. Histochemical and ultrastructural study on the innervation of human and porcine atrio-ventricular valves. Anat Embryol (Berl) 1984;169:159-65.
9. Filip DA, Radu A, Simionescu M. Interstitial cells of the heart valves possess characteristics similar to smooth muscle cells. Circ Res 1986;59:310-20.
10. Pelouch V, Dixon IMC, Golfman L, Beamish RE, Dhalla NS. Role of extracellular matrix proteins in heart function. Mol Cell Biochem 1993;129:101-20.
11. Shimizu M, Umeda K, Sugihara N, et al. Collagen remodelling in myocardia of patients with diabetes. J Clin Pathol 1993;46:32-6.
12. Shehadeh A, Regan TJ. Cardiac consequences of diabetes mellitus. Clin Cardiol 1995;18:301-5.
13. Riva E, Andreoni G, Bianchi R, et al. Changes in diastolic function and collagen content in normotensive and hypertensive rats with long-term streptozotocin-induced diabetes. Pharmacol Res 1998;37:233-40.
14. Jew JY, Fink CA, Williams TH. Tyrosine hydroxylase-and nitric oxide synthase-immunoreactive nerve fibers in mitral valve of young adult and aged Fischer 344 rats. J Auton Nerv Syst 1996;58:35-43.
15. Hope BT, Michael GJ, Knigge KM, Vincent SR. Neuronal NADPH diaphorase is a nitric oxide synthase. Proc Natl Acad Sci USA 1991;88:2811-4.
16. Williams TH. Mitral and tricuspid valve innervation. Br Heart J 1964;26:105-15.
17. Williams TH. Fast-conducting fibres in the mitral valve. Br Heart J 1964;26:554-7.
18. Smith RB. Intrinsic innervation of the atrioventricular and semilunar valves in various mammals. J Anat 1971;108: 115-21.
19. Hibbs RG, Ellison JP. The atrioventricular valves of the guinea-pig. II. An ultrastructural study. Am J Anat 1973;138:347-69.
20. Williams TH, Folan JC, Jew JY, Wang YF. Variations in atrioventricular valve innervation in four species of mammals. Am J Anat 1990;187:193-200.
21. Miller MR, Kasahara M. Studies on the nerve endings in the heart. Am J Anat 1964;115:217-34.
22. Kawano H, Kawai S, Okada R. Vagal innervation in the human atrioventricular valves. J Cardiol 1992;28:17-24 [discussion 25].
23. Kawano H, Kawai S, Shirai T, Okada R. Morphological study on vagal innervation in human atrioventricular valves using histochemical method. Jpn Circ J 1993;57: 753-9.
24. Ellison JP, Hibbs RG. The atrioventricular valves of the guinea-pig. I. A light microscopic study. Am J Anat 1973;138:331-45.
25. Jew JY, Williams TH, Fassbinder K, Zimmerman C. Do different neuronal populations occupy different structural/ functional domains in the rat mitral valve? FASEB J 1999 [Abstracts].
26. Klimaschewski L, Kummer W, Mayer B, et al. Nitric oxide synthase in cardiac nerve fibers and neurons of rat and guinea pig heart. Circ Res 1992;71:1533-7.
27. Marron K, Yacoub MH, Polak JM, et al. Innervation of human atrioventricular and arterial valves. Circulation 1996;94: 368-75.
28. Williams TH, Davisson R, Weiss R, Fassbinder K, Zimmerman C, Caldwell R. Effects of chemical lesioning on morphology and performance of rat mitral valves. FASEB J 1999 [Abstracts].
29. Mulholland DL, Gotlieb AI. Cell biology of valvular interstitial cells. Can J Cardiol 1996;12:231-6.
30. Wit AL, Fenoglio Jr JJ, Hordof AJ, Reemtsma K. Ultrastructure and transmembrane potentials of cardiac muscle in the human anterior mitral valve leaflet. Circulation 1979;59:1284-92.
31. Cooper T, Napolitano LM, Fitzgerald MJ, et al. Structural basis of cardiac valvar function. Arch Surg 1966;93:767-71.
32. Gross L, Kugel MA. Topographic anatomy and histology of the valves in the human heart. Am J Pathol 1931;7:445-74.
33. Fenoglio Jr J, Tuan due P. Ruptured chordae tendineae. An electron microscopic study. Hum Pathol 1972;3: 415-20.
34. Rozanski GJ, Jalife J. Automaticity in atrioventricular valve leaflets of rabbit heart. Am J Physiol 1986;250: H397-406.
35. Sonnenblick EH, Napolitano LM, Daggett WM, Cooper T. An intrinsic neuromuscular basis for mitral valve motion in the dog. Circ Res 1967;21:9-15.
36. Bassett AL, Fenoglio Jr JJ, Wit AL, Myerburg RJ, Gelband H. Electrophysiologic and ultrastructural characteristics of the canine tricuspid valve. Am J Physiol 1976;230: 1366-73.
37. Coghlan HC, Phares P, Cowley M, Copley D, James TN. Dysautonomia in mitral valve prolapse. Am J Med 1979;67:236-44.
38. Gaffney FA, Karlsson ES, Campbell W, et al. Autonomic dysfunction in women with mitral valve prolapse syndrome. Circulation 1979;59:894-901.
39. Gaffney FA, Bastian BC, Lane LB, et al. Abnormal cardiovascular regulation in the mitral valve prolapse syndrome. Am J Cardiol 1983;52:316-20.
40. Davies AO, Mares A, Pool JL, Taylor AA. Mitral valve prolapse with symptoms of β-adrenergic hypersensitivity. β2-Adrenergic receptor supercoupling with desensitization on isoproterenol exposure. Am J Med 1987;82: 193-201.
41. Kawano T, Oki T, Uchida T, et al. Innervation of the mitral valve in normal and prolapsed mitral valves. J Cardiol 1989;21:43-54.
42. Bell D, Acton R. Increased prevalence of mitral valve prolapse in IDDM. Diabetes Care 1996;19:672.
43. Goodkind M. Cardiac surgeon's heart valve map parallels human genome project. Stanford Report, October 25, 2000. p. 4.