Evaluation of the Protein Binding Ratio of Drugs by A Micro-Scale Ultracentrifugation Method

Journal of Pharmaceutical Sciences

Volumn 93, Issue 4, 2004, Pages 847-854

  Nakai, Daisuke ^a   Kumamoto, Kazuyo ^a   Sakikawa, Chisa ^a   Kosaka, Toshiyuki ^a   Tokui, Taro ^a  

^a DAIICHI SANKYO CO   (Japan)

Author keywords

ADME; Albumin; Alpha 1 acid glycoprotein; Distribution; Lipids lipoproteins; Protein binding

Indexed keywords

ALBUMIN; ALPHA 1 ANTITRYPSIN; ALPHA2 GLYCOPROTEIN; APOLIPOPROTEIN A1; APOLIPOPROTEIN E; CAFFEINE; DEXAMETHASONE; DIAZEPAM; DIGOXIN; DILTIAZEM; LIPID; LIPOPROTEIN; OROSOMUCOID; PHENYLBUTAZONE; PROBUCOL; PROPRANOLOL; VERAPAMIL; WARFARIN;

AMINO ACID SEQUENCE; ARTICLE; CONTAMINATION; CORRELATION FUNCTION; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG PROTEIN BINDING; ELECTROSPRAY; EQUILIBRIUM DIALYSIS; HUMAN; LIPOPHILICITY; LIQUID CHROMATOGRAPHY; MALE; NORMAL HUMAN; TANDEM MASS SPECTROMETRY; ULTRACENTRIFUGATION; ULTRAFILTRATION;

EID: 1842534877     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1002/jps.20012     Document Type: Article

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